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Basic Information Integrated Annotations

Tag Content
UUCD2 ID IUUC-Sce-106197
Ensembl Protein ID YAL041W
UniProt Accession P11433; D6VPH5; CDC24_YEAST
Genbank Protein ID AAA82871.1; AAC04990.1; DAA06945.1
Protein Name Cell division control protein 24; Calcium regulatory protein
Genbank Nucleotide ID M16809; U12980; BK006935
Gene Name CDC24; CLS4; YAL041W
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YAL041W YAL041W YAL041W
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Protein 3D Structure
PDBMMDB
Post-translational Modifications (PTMs)
dbPAFdbPTMPHOSIDABioGRID
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
ULD/UDP/UFD/PB1 PB1 17726178
Classification
Family E-value Score Start End
ULD/UDP/UFD/PB1 6.90e-24 82.3 762 854
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   ULD/UDP/UFD/PB1

   S: 2    vrvkvsykgeirs......faldlekpgkfedLlkavrt...ltelkn..sevalkYeDedGDlvtlksDedldkavslla.skksllrlliq 82
    + +++sy++++++ f+l +ek+++f+dL++a+++ +t+++n + +++kY+DedGD+v+l sDed+++a+++la +++++l+++++
   Q: 762 ILFRISYNNNSNNtssseiFTLLVEKVWNFDDLIMAINSkisNTHNNNisPITKIKYQDEDGDFVVLGSDEDWNVAKEMLAeNNEKFLNIRLY 854
    89***************************************999****999***************************************986 PP
   

Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description



     Promotes the exchange of CDC42-bound GDP by GTP. Controls the polarity of calmodulin, and the calcium regulatory process of bud emergence. CDC24 may be involved in the initial selection and organization of the budding site.
Promotes the exchange of CDC42-bound GDP by GTP. Controls the polarity of calmodulin, and the calcium regulatory process of bud emergence. CDC24 may be involved in the initial selection and organization of the budding site.
Protein Sequence
(Fasta)
MAIQTRFASG TSLSDLKPKP SATSISIPMQ NVMNKPVTEQ DSLFHICANI RKRLEVLPQL 60
KPFLQLAYQS SEVLSERQSL LLSQKQHQEL LKSNGANRDS SDLAPTLRSS SISTATSLMS 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Sce-106197|ULD,PB1|Saccharomyces cerevisiae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGCGATCC AAACCCGTTT TGCCTCGGGC ACATCTTTAT CCGATTTGAA ACCAAAACCA 60
AGTGCAACTT CCATCTCCAT ACCCATGCAA AATGTCATGA ACAAGCCTGT CACGGAACAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Sce-106197|ULD,PB1|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR010481--Cdc24/Scd1_N
IPR033511--Cdc24/Scd1_PH_dom
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR000270--PB1_dom
IPR011993--PH_dom-like
IPR001849--PH_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS51745--PB1
PS50003--PH_DOMAIN

Pfam

PF06395--CDC24
PF00564--PB1
PF00621--RhoGEF

SMART

SM00033--CH
SM00666--PB1
SM00233--PH
SM00325--RhoGEF

Gene Ontology

GO:0005935--C:cellular bud neck
GO:0005934--C:cellular bud tip
GO:0005737--C:cytoplasm
GO:0000131--C:incipient cellular bud site
GO:0043332--C:mating projection tip
GO:0005634--C:nucleus
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0000282--P:cellular bud site selection
GO:0072697--P:protein localization to cell cortex
GO:0007096--P:regulation of exit from mitosis
GO:0035023--P:regulation of Rho protein signal transduction
GO:0031106--P:septin ring organization
GO:0007264--P:small GTPase mediated signal transduction

KEGG sce:YAL041W
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002073 Ailuropoda melanoleuca 27.55 2.00e-23 102.00
IUUC-Apl-004117 Anas platyrhynchos 31.08 2.00e-20 91.70
IUUC-Aca-004793 Anolis carolinensis 28.46 5.00e-21 95.10
IUUC-Aly-006318 Arabidopsis lyrata 28.12 8.00e-03 33.50
IUUC-Ath-007468 Arabidopsis thaliana 29.69 2.00e-03 35.00
IUUC-Ago-008003 Ashbya gossypii 61.46 1.00e-173 601.00
IUUC-Acl-008142 Aspergillus clavatus 26.17 7.00e-41 160.00
IUUC-Afl-008481 Aspergillus flavus 26.04 1.00e-38 153.00
IUUC-Afu-009099 Aspergillus fumigatus 26.68 3.00e-42 165.00
IUUC-Ani-009276 Aspergillus nidulans 27.08 3.00e-40 158.00
IUUC-Ang-009549 Aspergillus niger 26.30 3.00e-42 165.00
IUUC-Aor-010216 Aspergillus oryzae 26.04 1.00e-38 153.00
IUUC-Ate-010338 Aspergillus terreus 26.70 4.00e-41 161.00
IUUC-Ame-010682 Astyanax mexicanus 26.77 9.00e-20 90.90
IUUC-Bgr-012058 Blumeria graminis 26.05 2.00e-38 152.00
IUUC-Bta-012674 Bos taurus 31.11 2.00e-17 83.60
IUUC-Bci-013634 Botrytis cinerea 27.44 3.00e-43 168.00
IUUC-Cel-018578 Caenorhabditis elegans 20.48 2.00e-10 59.70
IUUC-Cja-019555 Callithrix jacchus 27.37 7.00e-21 93.20
IUUC-Cfa-020578 Canis familiaris 26.83 1.00e-22 100.00
IUUC-Cpo-021726 Cavia porcellus 29.02 2.00e-15 76.60
IUUC-Cre-023018 Chlamydomonas reinhardtii 25.32 4.80e-02 30.80
IUUC-Csa-023331 Chlorocebus sabaeus 26.61 4.00e-20 91.30
IUUC-Cho-025069 Choloepus hoffmanni 26.67 1.00e-17 84.30
IUUC-Cin-025453 Ciona intestinalis 28.92 2.00e-19 89.00
IUUC-Csv-025922 Ciona savignyi 28.86 3.00e-19 88.20
IUUC-Cgl-026579 Colletotrichum gloeosporioides 31.08 8.00e-38 150.00
IUUC-Cne-027023 Cryptococcus neoformans 25.68 9.00e-34 137.00
IUUC-Cme-027247 Cyanidioschyzon merolae 25.81 2.00e-07 48.90
IUUC-Dre-028197 Danio rerio 31.34 3.00e-21 97.10
IUUC-Dno-029679 Dasypus novemcinctus 27.90 3.00e-23 102.00
IUUC-Dor-030739 Dipodomys ordii 27.17 2.00e-22 98.20
IUUC-Dse-031545 Dothistroma septosporum 30.56 7.00e-44 170.00
IUUC-Dme-031672 Drosophila melanogaster 29.67 1.00e-17 83.20
IUUC-Ete-032545 Echinops telfairi 26.09 7.00e-18 85.10
IUUC-Eca-034299 Equus caballus 30.60 1.00e-22 99.80
IUUC-Eeu-034720 Erinaceus europaeus 27.34 1.00e-18 87.80
IUUC-Fca-036416 Felis catus 28.48 3.00e-23 101.00
IUUC-Fal-037035 Ficedula albicollis 28.03 8.00e-20 91.30
IUUC-Fox-037710 Fusarium oxysporum 27.85 4.00e-39 154.00
IUUC-Fso-038080 Fusarium solani 29.63 2.00e-45 176.00
IUUC-Gmo-039587 Gadus morhua 32.11 2.00e-21 94.70
IUUC-Ggr-039728 Gaeumannomyces graminis 30.11 6.00e-34 137.00
IUUC-Gga-040841 Gallus gallus 30.23 1.00e-19 89.70
IUUC-Gac-042498 Gasterosteus aculeatus 32.85 7.00e-21 93.20
IUUC-Gma-043954 Glycine max 24.29 1.00e-03 36.60
IUUC-Ggo-044700 Gorilla gorilla 27.34 2.00e-19 90.50
IUUC-Hsa-045681 Homo sapiens 25.96 5.00e-21 94.70
IUUC-Itr-048380 Ictidomys tridecemlineatus 27.45 8.00e-23 99.80
IUUC-Kpa-049278 Komagataella pastoris 38.19 1.00e-93 335.00
IUUC-Lch-049639 Latimeria chalumnae 31.60 3.00e-22 97.80
IUUC-Lpe-050724 Leersia perrieri 31.75 2.10e-01 26.90
IUUC-Loc-051994 Lepisosteus oculatus 32.11 2.00e-21 95.10
IUUC-Lma-052955 Leptosphaeria maculans 30.42 4.00e-43 168.00
IUUC-Laf-054307 Loxodonta africana 26.29 5.00e-21 94.00
IUUC-Mcc-055305 Macaca mulatta 25.69 5.00e-21 93.20
IUUC-Meu-056376 Macropus eugenii 27.46 3.00e-19 88.20
IUUC-Mor-057139 Magnaporthe oryzae 31.51 8.00e-38 150.00
IUUC-Mpo-057433 Magnaporthe poae 30.46 1.00e-31 129.00
IUUC-Mtr-058322 Medicago truncatula 27.14 3.00e-04 39.30
IUUC-Mla-059044 Melampsora laricipopulina 31.45 7.00e-45 174.00
IUUC-Mga-059644 Meleagris gallopavo 28.79 3.00e-20 92.40
IUUC-Mvi-060486 Microbotryum violaceum 33.51 8.00e-59 220.00
IUUC-Mmr-061664 Microcebus murinus 26.29 2.00e-21 96.70
IUUC-Mdo-062404 Monodelphis domestica 29.46 4.00e-20 92.40
IUUC-Mmu-063143 Mus musculus 28.96 3.00e-20 92.80
IUUC-Mpu-066851 Mustela putorius furo 27.64 5.00e-24 105.00
IUUC-Mlu-066956 Myotis lucifugus 27.17 3.00e-22 99.00
IUUC-Nfi-068331 Neosartorya fischeri 27.20 3.00e-43 168.00
IUUC-Ncr-068819 Neurospora crassa 28.53 6.00e-35 140.00
IUUC-Nle-069174 Nomascus leucogenys 27.91 1.00e-20 91.70
IUUC-Opr-070209 Ochotona princeps 29.92 2.00e-21 95.50
IUUC-Ont-072091 Oreochromis niloticus 28.29 5.00e-20 91.30
IUUC-Oan-073722 Ornithorhynchus anatinus 26.93 5.00e-22 97.10
IUUC-Ocu-074885 Oryctolagus cuniculus 26.83 1.00e-21 97.10
IUUC-Ola-087155 Oryzias latipes 27.34 3.00e-21 95.90
IUUC-Oga-088758 Otolemur garnettii 30.30 8.00e-21 94.40
IUUC-Oar-090384 Ovis aries 30.22 5.00e-13 68.90
IUUC-Ptr-091555 Pan troglodytes 25.96 5.00e-21 94.00
IUUC-Pan-092037 Papio anubis 25.21 1.00e-20 94.00
IUUC-Psi-093865 Pelodiscus sinensis 30.25 2.00e-20 92.80
IUUC-Pma-094503 Petromyzon marinus 29.13 5.00e-15 74.70
IUUC-Pno-095127 Phaeosphaeria nodorum 29.52 2.00e-36 145.00
IUUC-Ppa-095579 Physcomitrella patens 30.00 5.00e-03 35.40
IUUC-Pfo-096918 Poecilia formosa 26.24 5.00e-21 95.50
IUUC-Pab-097910 Pongo abelii 25.68 3.00e-20 92.80
IUUC-Pca-100891 Procavia capensis 27.73 2.00e-19 90.10
IUUC-Ppe-101831 Prunus persica 33.33 8.00e-03 33.50
IUUC-Pva-102967 Pteropus vampyrus 27.05 7.00e-21 93.60
IUUC-Pgr-103400 Puccinia graminis 31.30 7.00e-50 190.00
IUUC-Ptt-103822 Puccinia triticina 27.66 3.00e-28 118.00
IUUC-Pte-104293 Pyrenophora teres 31.15 1.00e-43 169.00
IUUC-Pyt-104722 Pyrenophora triticirepentis 31.22 4.00e-43 167.00
IUUC-Rno-105479 Rattus norvegicus 26.98 3.00e-21 96.30
IUUC-Sha-107592 Sarcophilus harrisii 29.24 1.00e-21 97.10
IUUC-Sja-107728 Schizosaccharomyces japonicus 31.71 2.00e-45 175.00
IUUC-Spo-108284 Schizosaccharomyces pombe 33.07 3.00e-52 198.00
IUUC-Ssl-108541 Sclerotinia sclerotiorum 28.80 4.00e-43 168.00
IUUC-Sit-110315 Setaria italica 32.22 1.00e-03 36.20
IUUC-Sly-111227 Solanum lycopersicum 37.70 2.00e-03 35.40
IUUC-Stu-112269 Solanum tuberosum 37.70 1.00e-03 35.80
IUUC-Sar-113369 Sorex araneus 28.71 2.00e-17 81.60
IUUC-Sre-115126 Sporisorium reilianum 34.13 3.00e-64 238.00
IUUC-Ssc-115967 Sus scrofa 29.46 8.00e-14 71.20
IUUC-Tgu-117088 Taeniopygia guttata 30.23 1.00e-19 89.70
IUUC-Tru-118716 Takifugu rubripes 26.39 2.00e-21 97.10
IUUC-Tsy-118846 Tarsius syrichta 27.76 5.00e-19 86.70
IUUC-Tni-120887 Tetraodon nigroviridis 26.52 4.00e-20 92.40
IUUC-Tca-121171 Theobroma cacao 32.81 4.00e-03 34.30
IUUC-Tre-121935 Trichoderma reesei 30.13 5.00e-48 184.00
IUUC-Tvi-122300 Trichoderma virens 29.40 2.00e-47 182.00
IUUC-Tme-127216 Tuber melanosporum 32.66 3.00e-56 211.00
IUUC-Tbe-127248 Tupaia belangeri 27.73 1.00e-19 90.50
IUUC-Ttr-128429 Tursiops truncatus 29.78 1.00e-14 73.90
IUUC-Uma-129594 Ustilago maydis 33.87 2.00e-64 238.00
IUUC-Vda-129831 Verticillium dahliae 30.23 3.00e-33 135.00
IUUC-Vpa-130750 Vicugna pacos 28.18 7.00e-17 81.60
IUUC-Xtr-132676 Xenopus tropicalis 32.85 8.00e-20 89.70
IUUC-Xma-133871 Xiphophorus maculatus 26.24 4.00e-21 95.50
IUUC-Yli-134423 Yarrowia lipolytica 37.01 1.00e-73 269.00
IUUC-Zma-135022 Zea mays 31.91 9.20e-02 28.10
Created Date 25-Jun-2017

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