iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000007932.5	ENSBTAT00000056914.1	ENSBTAP00000051020.1
ENSBTAG00000007932.5	ENSBTAT00000037322.3	ENSBTAP00000037156.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.30e-15	57.2	80	135

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            v +lydy+a + ++L+++kGd++ v+   e++++W+++ + ++ k+G +P+n+v++++
   Q: 80   IVVALYDYDAIHHEDLSFQKGDQMVVL---EESGEWWRARSLATRKEGYIPSNYVARVN 135
           689************************...99*************************97 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

LGGRSSCEDP GCPPEEERAP RMGCVKSKFL RNGGKVSKTE PNTNPHSPLY VPDPTSSGKR 60
WPDSSNGNPP GSTEGSEDII VVALYDYDAI HHEDLSFQKG DQMVVLEESG EWWRARSLAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGGGACG CACCGCCGAG GCCTAGGGGC GAGTGGAAGG GGACGCGGAC AGTCCAGCGC 60
CAGAGGGCTC CCTCCCCTAA AGACGCACGG CACCGAAGCC CCTCGGAGCG CATCCCCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005654--C:nucleoplasm
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001284	Ailuropoda melanoleuca	91.44	0.00e+00	1003.00
IUUC-Apl-003285	Anas platyrhynchos	78.52	0.00e+00	814.00
IUUC-Aca-004724	Anolis carolinensis	77.73	0.00e+00	793.00
IUUC-Ame-011954	Astyanax mexicanus	75.89	0.00e+00	773.00
IUUC-Cja-019817	Callithrix jacchus	90.51	0.00e+00	940.00
IUUC-Cfa-020511	Canis familiaris	93.32	0.00e+00	1028.00
IUUC-Cpo-022538	Cavia porcellus	91.49	0.00e+00	956.00
IUUC-Csa-024143	Chlorocebus sabaeus	91.68	0.00e+00	961.00
IUUC-Dre-028157	Danio rerio	76.63	0.00e+00	794.00
IUUC-Dno-029761	Dasypus novemcinctus	91.07	0.00e+00	957.00
IUUC-Eca-034090	Equus caballus	92.18	0.00e+00	1013.00
IUUC-Fca-035937	Felis catus	88.55	0.00e+00	949.00
IUUC-Fal-036624	Ficedula albicollis	77.76	0.00e+00	804.00
IUUC-Gmo-039009	Gadus morhua	72.67	0.00e+00	760.00
IUUC-Gga-040296	Gallus gallus	75.35	0.00e+00	782.00
IUUC-Gac-042362	Gasterosteus aculeatus	73.77	0.00e+00	775.00
IUUC-Ggo-044570	Gorilla gorilla	91.06	0.00e+00	988.00
IUUC-Hsa-046378	Homo sapiens	91.25	0.00e+00	999.00
IUUC-Itr-048695	Ictidomys tridecemlineatus	87.81	0.00e+00	947.00
IUUC-Loc-052904	Lepisosteus oculatus	78.35	0.00e+00	823.00
IUUC-Laf-053654	Loxodonta africana	90.87	0.00e+00	956.00
IUUC-Mcc-055317	Macaca mulatta	91.67	0.00e+00	966.00
IUUC-Mga-060194	Meleagris gallopavo	80.62	0.00e+00	764.00
IUUC-Mmr-061510	Microcebus murinus	89.88	0.00e+00	951.00
IUUC-Mdo-062035	Monodelphis domestica	84.95	0.00e+00	900.00
IUUC-Mmu-064037	Mus musculus	90.08	0.00e+00	996.00
IUUC-Mpu-066874	Mustela putorius furo	92.66	0.00e+00	981.00
IUUC-Mlu-068202	Myotis lucifugus	89.68	0.00e+00	922.00
IUUC-Nle-069222	Nomascus leucogenys	91.27	0.00e+00	953.00
IUUC-Opr-070705	Ochotona princeps	87.29	0.00e+00	965.00
IUUC-Ont-072347	Oreochromis niloticus	82.29	0.00e+00	764.00
IUUC-Ocu-074490	Oryctolagus cuniculus	88.27	0.00e+00	932.00
IUUC-Ola-086521	Oryzias latipes	80.49	0.00e+00	771.00
IUUC-Oga-088153	Otolemur garnettii	90.89	0.00e+00	960.00
IUUC-Oar-090184	Ovis aries	96.72	0.00e+00	1040.00
IUUC-Ptr-090505	Pan troglodytes	87.45	0.00e+00	937.00
IUUC-Pan-092260	Papio anubis	91.87	0.00e+00	966.00
IUUC-Pma-094311	Petromyzon marinus	69.94	0.00e+00	740.00
IUUC-Pfo-096566	Poecilia formosa	75.54	0.00e+00	795.00
IUUC-Pva-103021	Pteropus vampyrus	93.65	0.00e+00	988.00
IUUC-Rno-105309	Rattus norvegicus	90.26	0.00e+00	955.00
IUUC-Sha-107099	Sarcophilus harrisii	84.25	0.00e+00	897.00
IUUC-Tgu-116912	Taeniopygia guttata	78.11	0.00e+00	802.00
IUUC-Tru-118449	Takifugu rubripes	81.35	0.00e+00	762.00
IUUC-Tae-123706	Triticum aestivum	31.40	3.00e-22	100.00
IUUC-Tur-126022	Triticum urartu	31.40	3.00e-22	100.00
IUUC-Tbe-128144	Tupaia belangeri	87.11	0.00e+00	803.00
IUUC-Xma-133902	Xiphophorus maculatus	76.04	0.00e+00	798.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence