iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096587

Ensembl Protein ID

ENSPFOP00000008810.2

UniProt Accession

A0A087XSQ7; A0A087XSQ7_POEFO

Genbank Protein ID

ENSPFOP00000008810

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

AYCK01010605

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000008606.2	ENSPFOT00000008822.2	ENSPFOP00000008810.2
ENSPFOG00000008606.2	ENSPFOT00000023229.1	ENSPFOP00000023350.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.10e-34	114.6	183	224
UBD/Beta-Prp	6.00e-73	246.2	13	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD ++k+WD+   +++++
   Q: 183  GHEKGVNCIDYysgGDkPYLISGADDRQVKIWDYQNKTCVQT 224
           8*********9999778****************999988875 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++++ +tg++D+ i+v++++t + vh +++h+d+
   Q: 13   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRASKFVARKNWVITGADDMQIRVFNYNTLERVHMFEAHSDY 101
           678999*********************************************************************************** PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +++++++p++ ++++ s+d  i++wd+e+++  +++++gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++ v+
   Q: 102  IRCIAVHPTQPYILTSSDDMLIKLWDWEKKWTCSQVFEGHTHYVMQIVINPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVN 189
           ******************************99999**********************************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++ s g  ++l+sg++d++vk+wd+q+++cv+tl+gh +nv++v f+p+  ++++gs+Dg++riW + +  l +tl++  ++v++v+
   Q: 190  CIDYYSGGdkPYLISGADDRQVKIWDYQNKTCVQTLEGHAQNVSCVSFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVC 278
           ***8887777******************************************************************************* PP
   S: 272  vlsfgdnvlvlg 283
           +l+ ++nv +  
   Q: 279  GLRGSNNVALGY 290
           *99999987433 PP

Organism

Poecilia formosa

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLDIKRR LTARSDRVKS VDLHPTEPWM LASLYNGSVC VWNHETQTLV KTFEVCDLPV 60
RASKFVARKN WVITGADDMQ IRVFNYNTLE RVHMFEAHSD YIRCIAVHPT QPYILTSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCGTCATTT AAAAACCCAA CATGTCACGT CACCATTTAC AGAACACGAT TCTCGCGAGA 60
TTTTCTTCCA GGAAGTTCCA CGTCAGTGTC CAATGCACTG CTCACTGTAA TAGAACCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0030903--P:notochord development
GO:0061053--P:somite development
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	53.04	0.00e+00	934.00
IUUC-Aml-002154	Ailuropoda melanoleuca	85.86	0.00e+00	1672.00
IUUC-Atr-003090	Amborella trichopoda	58.50	0.00e+00	1066.00
IUUC-Apl-003976	Anas platyrhynchos	90.73	0.00e+00	1691.00
IUUC-Aca-004301	Anolis carolinensis	93.38	0.00e+00	1675.00
IUUC-Aly-006508	Arabidopsis lyrata	60.87	0.00e+00	1090.00
IUUC-Ath-007630	Arabidopsis thaliana	61.62	0.00e+00	1108.00
IUUC-Ago-007914	Ashbya gossypii	46.49	0.00e+00	754.00
IUUC-Acl-008237	Aspergillus clavatus	56.51	0.00e+00	964.00
IUUC-Afl-008535	Aspergillus flavus	56.17	0.00e+00	912.00
IUUC-Afu-008845	Aspergillus fumigatus	54.99	0.00e+00	937.00
IUUC-Ani-009135	Aspergillus nidulans	56.23	0.00e+00	914.00
IUUC-Ang-009654	Aspergillus niger	55.89	0.00e+00	857.00
IUUC-Aor-009939	Aspergillus oryzae	53.69	0.00e+00	968.00
IUUC-Ate-010355	Aspergillus terreus	54.81	0.00e+00	917.00
IUUC-Ame-010922	Astyanax mexicanus	86.72	0.00e+00	1551.00
IUUC-Bgr-012249	Blumeria graminis	54.01	0.00e+00	922.00
IUUC-Bta-013579	Bos taurus	94.95	0.00e+00	1440.00
IUUC-Bci-013866	Botrytis cinerea	55.19	0.00e+00	922.00
IUUC-Bdi-015046	Brachypodium distachyon	62.42	0.00e+00	1101.00
IUUC-Bol-015731	Brassica oleracea	60.82	0.00e+00	1107.00
IUUC-Bra-016617	Brassica rapa	60.88	0.00e+00	1077.00
IUUC-Cel-018387	Caenorhabditis elegans	64.89	0.00e+00	1176.00
IUUC-Cja-019145	Callithrix jacchus	86.09	0.00e+00	1671.00
IUUC-Cfa-020564	Canis familiaris	93.02	0.00e+00	1670.00
IUUC-Cpo-022201	Cavia porcellus	92.89	0.00e+00	1668.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	59.32	0.00e+00	988.00
IUUC-Csa-023383	Chlorocebus sabaeus	93.83	0.00e+00	1145.00
IUUC-Cho-024454	Choloepus hoffmanni	88.16	0.00e+00	1364.00
IUUC-Cin-025681	Ciona intestinalis	78.08	0.00e+00	1368.00
IUUC-Csv-026012	Ciona savignyi	77.07	0.00e+00	1342.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	52.37	0.00e+00	841.00
IUUC-Cne-026986	Cryptococcus neoformans	50.72	0.00e+00	907.00
IUUC-Cme-027219	Cyanidioschyzon merolae	47.81	0.00e+00	853.00
IUUC-Dre-027846	Danio rerio	95.10	0.00e+00	1725.00
IUUC-Dor-030462	Dipodomys ordii	88.87	0.00e+00	1238.00
IUUC-Dse-031268	Dothistroma septosporum	54.96	0.00e+00	951.00
IUUC-Dme-031791	Drosophila melanogaster	72.27	0.00e+00	1268.00
IUUC-Ete-033166	Echinops telfairi	84.77	0.00e+00	986.00
IUUC-Eca-034180	Equus caballus	90.77	0.00e+00	1615.00
IUUC-Eeu-035086	Erinaceus europaeus	78.85	0.00e+00	793.00
IUUC-Fca-036265	Felis catus	85.67	0.00e+00	1673.00
IUUC-Fal-037202	Ficedula albicollis	92.11	0.00e+00	1633.00
IUUC-Fox-037711	Fusarium oxysporum	55.91	0.00e+00	878.00
IUUC-Fso-038268	Fusarium solani	55.64	0.00e+00	879.00
IUUC-Gmo-039046	Gadus morhua	96.09	0.00e+00	1716.00
IUUC-Ggr-039863	Gaeumannomyces graminis	55.24	0.00e+00	898.00
IUUC-Gga-041112	Gallus gallus	90.63	0.00e+00	1693.00
IUUC-Gac-041733	Gasterosteus aculeatus	96.96	0.00e+00	1713.00
IUUC-Gma-042910	Glycine max	62.15	0.00e+00	1114.00
IUUC-Ggo-044984	Gorilla gorilla	85.88	0.00e+00	1664.00
IUUC-Hsa-046698	Homo sapiens	85.88	0.00e+00	1665.00
IUUC-Hvu-047669	Hordeum vulgare	70.34	1.00e-167	582.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	93.13	0.00e+00	1667.00
IUUC-Kpa-049265	Komagataella pastoris	49.44	0.00e+00	867.00
IUUC-Lch-050473	Latimeria chalumnae	87.25	0.00e+00	1702.00
IUUC-Lpe-051579	Leersia perrieri	60.99	0.00e+00	1089.00
IUUC-Loc-052675	Lepisosteus oculatus	94.94	0.00e+00	1712.00
IUUC-Lma-053218	Leptosphaeria maculans	55.09	0.00e+00	924.00
IUUC-Laf-053757	Loxodonta africana	85.79	0.00e+00	1660.00
IUUC-Mcc-054859	Macaca mulatta	86.09	0.00e+00	1670.00
IUUC-Meu-056174	Macropus eugenii	89.74	0.00e+00	709.00
IUUC-Mor-057264	Magnaporthe oryzae	55.47	0.00e+00	883.00
IUUC-Mpo-057538	Magnaporthe poae	55.49	0.00e+00	912.00
IUUC-Mtr-058310	Medicago truncatula	62.27	0.00e+00	1124.00
IUUC-Mla-058937	Melampsora laricipopulina	53.33	0.00e+00	903.00
IUUC-Mga-059875	Meleagris gallopavo	90.43	0.00e+00	1687.00
IUUC-Mvi-060240	Microbotryum violaceum	50.81	0.00e+00	906.00
IUUC-Mmr-061261	Microcebus murinus	86.20	0.00e+00	1673.00
IUUC-Mdo-062076	Monodelphis domestica	90.12	0.00e+00	1688.00
IUUC-Mmu-063324	Mus musculus	91.16	0.00e+00	1669.00
IUUC-Mac-064636	Musa acuminata	59.10	0.00e+00	1083.00
IUUC-Mpu-065961	Mustela putorius furo	92.90	0.00e+00	1667.00
IUUC-Mlu-067059	Myotis lucifugus	92.31	0.00e+00	1615.00
IUUC-Nfi-068277	Neosartorya fischeri	54.70	0.00e+00	926.00
IUUC-Ncr-068659	Neurospora crassa	53.07	0.00e+00	912.00
IUUC-Nle-069034	Nomascus leucogenys	85.99	0.00e+00	1670.00
IUUC-Opr-070334	Ochotona princeps	94.42	0.00e+00	1477.00
IUUC-Ont-071563	Oreochromis niloticus	91.73	0.00e+00	1768.00
IUUC-Oan-073416	Ornithorhynchus anatinus	93.15	0.00e+00	1602.00
IUUC-Ocu-074522	Oryctolagus cuniculus	85.99	0.00e+00	1665.00
IUUC-Oba-075760	Oryza barthii	60.74	0.00e+00	1073.00
IUUC-Obr-076163	Oryza brachyantha	62.59	0.00e+00	1098.00
IUUC-Ogl-077450	Oryza glaberrima	61.98	0.00e+00	1100.00
IUUC-Ogu-078994	Oryza glumaepatula	60.74	0.00e+00	1071.00
IUUC-Oin-079856	Oryza indica	60.39	0.00e+00	1073.00
IUUC-Olo-080731	Oryza longistaminata	58.84	0.00e+00	1059.00
IUUC-Ome-081762	Oryza meridionalis	56.37	0.00e+00	995.00
IUUC-Oni-082324	Oryza nivara	60.74	0.00e+00	1073.00
IUUC-Opu-083400	Oryza punctata	58.32	0.00e+00	1059.00
IUUC-Oru-084829	Oryza rufipogon	60.74	0.00e+00	1073.00
IUUC-Osa-086026	Oryza sativa	61.98	0.00e+00	1103.00
IUUC-Ola-087245	Oryzias latipes	93.35	0.00e+00	1796.00
IUUC-Olu-087655	Ostreococcus lucimarinus	59.73	0.00e+00	1051.00
IUUC-Oga-088163	Otolemur garnettii	87.26	0.00e+00	1597.00
IUUC-Oar-089842	Ovis aries	92.90	0.00e+00	1669.00
IUUC-Ptr-090501	Pan troglodytes	85.99	0.00e+00	1667.00
IUUC-Pan-092011	Papio anubis	86.20	0.00e+00	1672.00
IUUC-Psi-093308	Pelodiscus sinensis	93.76	0.00e+00	1688.00
IUUC-Pma-094695	Petromyzon marinus	80.89	0.00e+00	1441.00
IUUC-Pno-094785	Phaeosphaeria nodorum	62.07	3.00e-111	395.00
IUUC-Ppa-095911	Physcomitrella patens	61.25	0.00e+00	1121.00
IUUC-Pab-097926	Pongo abelii	84.07	0.00e+00	1579.00
IUUC-Pop-099634	Populus trichocarpa	61.91	0.00e+00	1105.00
IUUC-Pca-100965	Procavia capensis	91.23	0.00e+00	1624.00
IUUC-Ppe-101470	Prunus persica	61.67	0.00e+00	1110.00
IUUC-Pva-102451	Pteropus vampyrus	88.12	0.00e+00	1230.00
IUUC-Pgr-103453	Puccinia graminis	52.96	0.00e+00	918.00
IUUC-Ptt-103868	Puccinia triticina	53.06	0.00e+00	913.00
IUUC-Pte-104274	Pyrenophora teres	55.89	0.00e+00	956.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	55.24	0.00e+00	904.00
IUUC-Rno-105979	Rattus norvegicus	80.73	0.00e+00	1224.00
IUUC-Sce-106269	Saccharomyces cerevisiae	47.04	0.00e+00	780.00
IUUC-Sha-106905	Sarcophilus harrisii	90.99	0.00e+00	1683.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	47.47	0.00e+00	828.00
IUUC-Spo-108299	Schizosaccharomyces pombe	46.27	0.00e+00	822.00
IUUC-Smo-108695	Selaginella moellendorffii	61.98	0.00e+00	1078.00
IUUC-Sit-110239	Setaria italica	60.60	0.00e+00	1103.00
IUUC-Sly-111525	Solanum lycopersicum	61.07	0.00e+00	1114.00
IUUC-Stu-112906	Solanum tuberosum	59.72	0.00e+00	989.00
IUUC-Sar-113472	Sorex araneus	87.06	0.00e+00	1121.00
IUUC-Sbi-114052	Sorghum bicolor	62.92	0.00e+00	1115.00
IUUC-Sre-115040	Sporisorium reilianum	51.56	0.00e+00	911.00
IUUC-Ssc-115593	Sus scrofa	86.09	0.00e+00	1673.00
IUUC-Tgu-117239	Taeniopygia guttata	92.14	0.00e+00	1687.00
IUUC-Tru-118025	Takifugu rubripes	96.61	0.00e+00	1741.00
IUUC-Tsy-118824	Tarsius syrichta	86.46	0.00e+00	1132.00
IUUC-Tni-120142	Tetraodon nigroviridis	97.40	0.00e+00	1741.00
IUUC-Tca-121613	Theobroma cacao	61.55	0.00e+00	1108.00
IUUC-Tre-122072	Trichoderma reesei	55.24	0.00e+00	927.00
IUUC-Tvi-122546	Trichoderma virens	54.74	0.00e+00	913.00
IUUC-Tae-125292	Triticum aestivum	61.53	0.00e+00	1092.00
IUUC-Tur-126283	Triticum urartu	53.90	0.00e+00	933.00
IUUC-Tme-127041	Tuber melanosporum	55.76	0.00e+00	973.00
IUUC-Tbe-127770	Tupaia belangeri	88.70	0.00e+00	1236.00
IUUC-Ttr-129294	Tursiops truncatus	86.09	0.00e+00	1671.00
IUUC-Uma-129351	Ustilago maydis	50.67	0.00e+00	901.00
IUUC-Vda-129716	Verticillium dahliae	55.36	0.00e+00	948.00
IUUC-Vpa-130037	Vicugna pacos	75.30	0.00e+00	828.00
IUUC-Vvi-131689	Vitis vinifera	62.45	0.00e+00	1103.00
IUUC-Xtr-132633	Xenopus tropicalis	89.93	0.00e+00	1669.00
IUUC-Xma-133347	Xiphophorus maculatus	97.64	0.00e+00	1876.00
IUUC-Yli-134455	Yarrowia lipolytica	50.76	0.00e+00	842.00
IUUC-Zma-135706	Zea mays	60.44	0.00e+00	1115.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence