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Tag Content
UUCD2 ID IUUC-Dre-028215
UUCD1 version UUC-DaR-01305
Ensembl Protein ID ENSDARP00000024623.7
UniProt Accession Q7ZUV2; KTNB1_DANRE
Genbank Protein ID AAH47819.1
Protein Name Katanin p80 WD40 repeat-containing subunit B1; p80 katanin
Genbank Nucleotide ID BC047819
Gene Name katnb1; zgc:56071
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000005456.10 ENSDART00000014632.9 ENSDARP00000024623.7
ENSDARG00000005456.10 ENSDART00000174099.1 ENSDARP00000143087.1
ENSDARG00000005456.10 ENSDART00000130282.1 ENSDARP00000110726.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.10e-44 147.9 145 177
UBD/Beta-Prp 1.90e-70 238.3 14 176
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHt  v+claf +d + l+s+sdD t+k+WDl 
   Q: 145  GHTQAVRCLAFsPDgKWLASASDDSTVKLWDLI 177
           8***********999****************85 PP
   

   UBD/Beta-Prp
   S: 88   htlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl 175
           + + +h+++v sl + + sg  l++G++d  +++w +++  c+   l+gh+++v c+++++++  +v+Gsl + +rlWdl+ +k+lrtl
   Q: 14   QEIVAHSSNVSSLVLGKsSGRLLATGGEDCRVNIWAVSKPNCIM-SLTGHTSAVGCIQFNSSEERVVAGSLSGSLRLWDLEAAKILRTL 101
           44558************677************************.******************************************** PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
            g h+ s+ sl+f++ g++l+sgs d+ +klwd++++ cv +++ght+ v++++fsp++++l+s+s+D ++++Wdl
   Q: 102  MG-HKASISSLDFHPMGEYLASGSVDSNIKLWDVRRKGCVFRYKGHTQAVRCLAFSPDGKWLASASDDSTVKLWDL 176
           *9.***********************************************************************96 PP
   
Organism Danio rerio
Functional Description
(View)

Functional Description


     Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
 Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
Protein Sequence
(Fasta)
MALTNTTITS WKLQEIVAHS SNVSSLVLGK SSGRLLATGG EDCRVNIWAV SKPNCIMSLT 60
GHTSAVGCIQ FNSSEERVVA GSLSGSLRLW DLEAAKILRT LMGHKASISS LDFHPMGEYL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028215|E3,WD_repeat;UBD,Beta-Prp|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GATGTGTTGA AGGTTGCTGC AGTTGCATAG AGACAGACAT GTAATGCGCA TGCCCACTCT 60
GAATGCGCGC ACTCGGATCT TTTTTCGTCC TAGCCTAACT AATCTTTTTC TCATTGGTGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028215|E3,WD_repeat;UBD,Beta-Prp|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF13925--Katanin_con80
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0000922--C:spindle pole
GO:0007420--P:brain development
GO:0051301--P:cell division
GO:0051013--P:microtubule severing
GO:0030901--P:midbrain development
GO:0007067--P:mitotic nuclear division
KEGG dre:406291
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000954 Aegilops tauschii 45.69 1.00e-84 308.00
IUUC-Aml-002187 Ailuropoda melanoleuca 60.88 0.00e+00 787.00
IUUC-Atr-002899 Amborella trichopoda 53.77 4.00e-101 362.00
IUUC-Apl-003305 Anas platyrhynchos 62.08 0.00e+00 828.00
IUUC-Aca-004635 Anolis carolinensis 61.79 0.00e+00 775.00
IUUC-Aly-005711 Arabidopsis lyrata 51.83 3.00e-101 363.00
IUUC-Ath-007606 Arabidopsis thaliana 51.83 3.00e-101 363.00
IUUC-Ame-010870 Astyanax mexicanus 71.84 2.00e-135 475.00
IUUC-Bta-012527 Bos taurus 62.32 0.00e+00 825.00
IUUC-Bdi-014652 Brachypodium distachyon 52.96 5.00e-103 369.00
IUUC-Bol-015242 Brassica oleracea 49.84 1.00e-98 354.00
IUUC-Bra-017390 Brassica rapa 51.13 5.00e-99 355.00
IUUC-Cja-019706 Callithrix jacchus 60.92 0.00e+00 777.00
IUUC-Cfa-020139 Canis familiaris 51.94 4.00e-132 465.00
IUUC-Cpo-021710 Cavia porcellus 60.86 0.00e+00 807.00
IUUC-Cre-022746 Chlamydomonas reinhardtii 37.67 1.00e-61 231.00
IUUC-Csa-023546 Chlorocebus sabaeus 61.58 0.00e+00 759.00
IUUC-Cin-025156 Ciona intestinalis 38.84 1.00e-144 506.00
IUUC-Csv-025962 Ciona savignyi 48.26 4.00e-85 307.00
IUUC-Dno-029314 Dasypus novemcinctus 60.00 0.00e+00 786.00
IUUC-Dor-030482 Dipodomys ordii 61.00 0.00e+00 829.00
IUUC-Dme-032188 Drosophila melanogaster 40.45 5.00e-64 239.00
IUUC-Eca-034143 Equus caballus 61.49 0.00e+00 803.00
IUUC-Fca-035924 Felis catus 60.06 0.00e+00 800.00
IUUC-Fal-037387 Ficedula albicollis 61.06 0.00e+00 826.00
IUUC-Gmo-038692 Gadus morhua 67.63 7.00e-160 557.00
IUUC-Gga-040597 Gallus gallus 61.06 0.00e+00 837.00
IUUC-Gac-042004 Gasterosteus aculeatus 72.29 2.00e-179 622.00
IUUC-Gma-044134 Glycine max 52.49 3.00e-99 356.00
IUUC-Ggo-044761 Gorilla gorilla 61.44 0.00e+00 784.00
IUUC-Hsa-045698 Homo sapiens 60.66 0.00e+00 796.00
IUUC-Hvu-047649 Hordeum vulgare 50.47 8.00e-103 368.00
IUUC-Itr-048697 Ictidomys tridecemlineatus 62.12 0.00e+00 797.00
IUUC-Lch-049674 Latimeria chalumnae 64.80 0.00e+00 904.00
IUUC-Lpe-051554 Leersia perrieri 52.96 2.00e-104 374.00
IUUC-Loc-052623 Lepisosteus oculatus 73.60 0.00e+00 987.00
IUUC-Laf-054587 Loxodonta africana 61.58 0.00e+00 825.00
IUUC-Mcc-055851 Macaca mulatta 61.44 0.00e+00 784.00
IUUC-Meu-056704 Macropus eugenii 62.89 0.00e+00 870.00
IUUC-Mtr-058053 Medicago truncatula 52.49 2.00e-103 370.00
IUUC-Mga-059608 Meleagris gallopavo 61.16 0.00e+00 830.00
IUUC-Mmr-061154 Microcebus murinus 62.39 0.00e+00 799.00
IUUC-Mdo-062365 Monodelphis domestica 60.34 0.00e+00 818.00
IUUC-Mmu-063754 Mus musculus 61.03 0.00e+00 808.00
IUUC-Mac-064667 Musa acuminata 53.40 8.00e-101 360.00
IUUC-Mpu-066245 Mustela putorius furo 67.91 1.00e-156 546.00
IUUC-Mlu-067692 Myotis lucifugus 62.21 0.00e+00 805.00
IUUC-Nle-070051 Nomascus leucogenys 62.01 0.00e+00 781.00
IUUC-Opr-070855 Ochotona princeps 62.73 0.00e+00 815.00
IUUC-Ont-071883 Oreochromis niloticus 67.04 0.00e+00 919.00
IUUC-Oan-073293 Ornithorhynchus anatinus 61.98 0.00e+00 770.00
IUUC-Ocu-074644 Oryctolagus cuniculus 60.74 0.00e+00 815.00
IUUC-Oba-075448 Oryza barthii 51.97 2.00e-103 370.00
IUUC-Obr-076385 Oryza brachyantha 52.30 8.00e-104 371.00
IUUC-Ogl-077427 Oryza glaberrima 51.97 2.00e-103 370.00
IUUC-Ogu-078062 Oryza glumaepatula 47.62 2.00e-93 337.00
IUUC-Oin-079811 Oryza indica 52.22 1.00e-100 361.00
IUUC-Olo-080245 Oryza longistaminata 52.22 1.00e-100 361.00
IUUC-Ome-081239 Oryza meridionalis 52.38 2.00e-100 360.00
IUUC-Oni-082640 Oryza nivara 51.97 2.00e-103 370.00
IUUC-Opu-083748 Oryza punctata 52.30 7.00e-104 372.00
IUUC-Oru-084609 Oryza rufipogon 51.97 2.00e-103 370.00
IUUC-Osa-085801 Oryza sativa 47.46 1.00e-93 338.00
IUUC-Ola-087483 Oryzias latipes 60.90 0.00e+00 715.00
IUUC-Oga-087964 Otolemur garnettii 61.66 0.00e+00 815.00
IUUC-Oar-089483 Ovis aries 61.26 0.00e+00 792.00
IUUC-Ptr-091387 Pan troglodytes 60.66 0.00e+00 796.00
IUUC-Pan-092623 Papio anubis 61.44 0.00e+00 784.00
IUUC-Psi-093830 Pelodiscus sinensis 59.91 0.00e+00 824.00
IUUC-Pma-094135 Petromyzon marinus 36.58 1.00e-33 136.00
IUUC-Ppa-095379 Physcomitrella patens 52.68 9.00e-96 345.00
IUUC-Pfo-096755 Poecilia formosa 66.19 0.00e+00 922.00
IUUC-Pab-097564 Pongo abelii 59.39 0.00e+00 675.00
IUUC-Pop-099149 Populus trichocarpa 52.82 4.00e-103 369.00
IUUC-Pca-100357 Procavia capensis 77.14 5.00e-99 355.00
IUUC-Ppe-101237 Prunus persica 51.41 8.00e-104 371.00
IUUC-Pva-102397 Pteropus vampyrus 59.05 0.00e+00 751.00
IUUC-Rno-105349 Rattus norvegicus 62.61 0.00e+00 826.00
IUUC-Smo-109379 Selaginella moellendorffii 48.66 1.00e-100 360.00
IUUC-Sit-110360 Setaria italica 52.63 7.00e-104 372.00
IUUC-Sly-111307 Solanum lycopersicum 52.82 9.00e-98 351.00
IUUC-Stu-112462 Solanum tuberosum 52.56 6.00e-95 341.00
IUUC-Sar-112953 Sorex araneus 60.96 2.00e-79 290.00
IUUC-Sbi-114389 Sorghum bicolor 48.14 1.00e-94 341.00
IUUC-Ssc-115949 Sus scrofa 59.13 5.00e-168 584.00
IUUC-Tgu-117461 Taeniopygia guttata 60.57 0.00e+00 850.00
IUUC-Tru-117865 Takifugu rubripes 66.05 0.00e+00 924.00
IUUC-Tsy-119036 Tarsius syrichta 73.23 2.00e-51 196.00
IUUC-Tni-120903 Tetraodon nigroviridis 63.79 0.00e+00 872.00
IUUC-Tca-121185 Theobroma cacao 51.83 1.00e-100 362.00
IUUC-Tae-125307 Triticum aestivum 51.10 9.00e-104 371.00
IUUC-Tur-126181 Triticum urartu 46.78 9.00e-92 332.00
IUUC-Tbe-127518 Tupaia belangeri 67.50 2.00e-78 286.00
IUUC-Ttr-128172 Tursiops truncatus 61.21 0.00e+00 796.00
IUUC-Vvi-131489 Vitis vinifera 53.82 3.00e-104 373.00
IUUC-Xtr-132915 Xenopus tropicalis 60.63 0.00e+00 828.00
IUUC-Xma-134133 Xiphophorus maculatus 65.76 0.00e+00 910.00
Created Date 25-Jun-2017

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