iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044775

UUCD1 version

UUC-GoG-00472

Ensembl Protein ID

ENSGGOP00000011596.2

UniProt Accession

G3R892; G3R892_GORGO

Protein Name

Uncharacterized protein

Gene Name

AMBRA1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000011880.2	ENSGGOT00000022614.1	ENSGGOP00000022187.1
ENSGGOG00000011880.2	ENSGGOT00000011931.2	ENSGGOP00000011596.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.50e-08	32.5	93	126

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd..tllvsGsdDgtikvWDlr 31
           gH    +c+ f ++  +l++sG+ Dg +++WDl+
   Q: 93   GHRRTPWCVTFhPTisGLIASGCLDGEVRIWDLH 126
           6777779*****76779***************97 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MKVVPEKNAV RILWGRERGA RAMGAQRLLQ ELVEDKTRWM KWEGKRVELP DSPRSTFLLA 60
FSPDRTLLAS THVNHNIYIT EVKTGKCVHS LIGHRRTPWC VTFHPTISGL IASGCLDGEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGGGATTAA TGAAGAGCCA CCAGACTATC TTTATGGAGA ATCTAGATTG GGAAGTTAAG 60
CTAAGAATGT GCATTTTTGA AAAAGTTTTT ATGGTAGAAG AGAATGTATA TCAGAGGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005930--C:axoneme
GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0045335--C:phagocytic vesicle
GO:0006914--P:autophagy
GO:0008285--P:negative regulation of cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0021915--P:neural tube development
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:2000785--P:regulation of autophagosome assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001917	Ailuropoda melanoleuca	97.33	1.00e-169	590.00
IUUC-Atr-002557	Amborella trichopoda	37.74	3.00e-30	127.00
IUUC-Apl-004186	Anas platyrhynchos	82.64	0.00e+00	916.00
IUUC-Aca-004419	Anolis carolinensis	84.49	0.00e+00	991.00
IUUC-Aly-006308	Arabidopsis lyrata	37.85	1.00e-28	121.00
IUUC-Ath-007656	Arabidopsis thaliana	36.92	4.00e-28	120.00
IUUC-Ame-011354	Astyanax mexicanus	70.77	0.00e+00	765.00
IUUC-Bta-012455	Bos taurus	93.60	0.00e+00	1041.00
IUUC-Bdi-014580	Brachypodium distachyon	42.33	4.00e-30	126.00
IUUC-Bol-016094	Brassica oleracea	40.22	1.00e-28	121.00
IUUC-Bra-017308	Brassica rapa	40.76	1.00e-29	125.00
IUUC-Cja-019073	Callithrix jacchus	94.78	0.00e+00	1185.00
IUUC-Cfa-020994	Canis familiaris	97.80	0.00e+00	1106.00
IUUC-Cpo-022101	Cavia porcellus	91.60	0.00e+00	995.00
IUUC-Csa-023273	Chlorocebus sabaeus	98.98	0.00e+00	1121.00
IUUC-Cin-025567	Ciona intestinalis	54.64	7.00e-56	211.00
IUUC-Csv-026005	Ciona savignyi	51.26	5.00e-56	210.00
IUUC-Dre-028282	Danio rerio	70.11	0.00e+00	745.00
IUUC-Dno-029948	Dasypus novemcinctus	94.63	0.00e+00	1018.00
IUUC-Dor-030568	Dipodomys ordii	95.58	5.00e-163	568.00
IUUC-Ete-032864	Echinops telfairi	83.01	0.00e+00	729.00
IUUC-Eca-034392	Equus caballus	97.97	0.00e+00	1114.00
IUUC-Eeu-034440	Erinaceus europaeus	96.74	6.00e-167	581.00
IUUC-Fca-035359	Felis catus	89.20	0.00e+00	953.00
IUUC-Fal-037483	Ficedula albicollis	84.11	0.00e+00	964.00
IUUC-Gmo-039343	Gadus morhua	78.74	0.00e+00	758.00
IUUC-Gga-040787	Gallus gallus	92.58	1.00e-145	510.00
IUUC-Gac-041321	Gasterosteus aculeatus	80.89	0.00e+00	786.00
IUUC-Gma-044022	Glycine max	36.63	3.00e-29	123.00
IUUC-Hsa-045708	Homo sapiens	99.66	0.00e+00	1109.00
IUUC-Hvu-047536	Hordeum vulgare	41.57	1.00e-29	124.00
IUUC-Itr-048376	Ictidomys tridecemlineatus	96.86	2.00e-174	605.00
IUUC-Lch-050255	Latimeria chalumnae	85.96	0.00e+00	824.00
IUUC-Lpe-050684	Leersia perrieri	41.76	2.00e-30	127.00
IUUC-Loc-052881	Lepisosteus oculatus	77.32	0.00e+00	796.00
IUUC-Laf-053342	Loxodonta africana	95.37	0.00e+00	1077.00
IUUC-Mcc-055848	Macaca mulatta	98.09	0.00e+00	1047.00
IUUC-Meu-056320	Macropus eugenii	92.51	6.00e-149	521.00
IUUC-Mtr-058685	Medicago truncatula	39.68	3.00e-29	123.00
IUUC-Mga-059401	Meleagris gallopavo	96.74	0.00e+00	663.00
IUUC-Mmr-061037	Microcebus murinus	96.81	0.00e+00	1019.00
IUUC-Mdo-062484	Monodelphis domestica	69.38	0.00e+00	709.00
IUUC-Mmu-064090	Mus musculus	93.96	0.00e+00	1018.00
IUUC-Mac-065675	Musa acuminata	34.89	2.00e-29	124.00
IUUC-Mpu-066165	Mustela putorius furo	97.46	0.00e+00	1104.00
IUUC-Mlu-068038	Myotis lucifugus	92.63	0.00e+00	1062.00
IUUC-Nle-069361	Nomascus leucogenys	98.42	0.00e+00	763.00
IUUC-Opr-070360	Ochotona princeps	93.45	0.00e+00	875.00
IUUC-Ont-071277	Oreochromis niloticus	79.58	0.00e+00	780.00
IUUC-Oan-073623	Ornithorhynchus anatinus	80.43	0.00e+00	890.00
IUUC-Ocu-074600	Oryctolagus cuniculus	97.29	0.00e+00	1103.00
IUUC-Oba-075024	Oryza barthii	38.19	4.00e-32	133.00
IUUC-Obr-076172	Oryza brachyantha	34.71	1.00e-32	135.00
IUUC-Ogl-077411	Oryza glaberrima	38.19	7.00e-32	132.00
IUUC-Ogu-078025	Oryza glumaepatula	38.19	7.00e-32	133.00
IUUC-Oni-082463	Oryza nivara	38.19	5.00e-32	133.00
IUUC-Opu-084041	Oryza punctata	38.19	1.00e-31	131.00
IUUC-Oru-085075	Oryza rufipogon	38.19	2.00e-31	131.00
IUUC-Osa-085781	Oryza sativa	38.19	6.00e-32	132.00
IUUC-Ola-086729	Oryzias latipes	79.80	0.00e+00	785.00
IUUC-Olu-087735	Ostreococcus lucimarinus	40.32	7.00e-24	105.00
IUUC-Oga-089113	Otolemur garnettii	95.81	0.00e+00	998.00
IUUC-Oar-090171	Ovis aries	97.74	0.00e+00	907.00
IUUC-Ptr-090970	Pan troglodytes	99.83	0.00e+00	1111.00
IUUC-Pan-092778	Papio anubis	98.98	0.00e+00	1120.00
IUUC-Psi-093571	Pelodiscus sinensis	85.36	0.00e+00	991.00
IUUC-Pma-094563	Petromyzon marinus	74.58	2.00e-106	378.00
IUUC-Ppa-095832	Physcomitrella patens	36.70	1.00e-30	128.00
IUUC-Pfo-097365	Poecilia formosa	80.09	0.00e+00	696.00
IUUC-Pab-098647	Pongo abelii	99.23	0.00e+00	964.00
IUUC-Pop-099742	Populus trichocarpa	40.32	1.00e-29	124.00
IUUC-Pca-101035	Procavia capensis	79.50	8.00e-162	564.00
IUUC-Ppe-101411	Prunus persica	37.56	2.00e-29	124.00
IUUC-Pva-103187	Pteropus vampyrus	98.54	0.00e+00	702.00
IUUC-Rno-105701	Rattus norvegicus	94.63	0.00e+00	1010.00
IUUC-Sha-107612	Sarcophilus harrisii	86.45	0.00e+00	971.00
IUUC-Smo-108871	Selaginella moellendorffii	39.08	6.00e-27	115.00
IUUC-Sit-110786	Setaria italica	38.12	2.00e-32	134.00
IUUC-Sly-110859	Solanum lycopersicum	38.10	7.00e-32	132.00
IUUC-Stu-112031	Solanum tuberosum	38.57	6.00e-32	132.00
IUUC-Sar-113242	Sorex araneus	78.68	3.00e-173	602.00
IUUC-Ssc-116094	Sus scrofa	95.31	0.00e+00	1024.00
IUUC-Tru-118308	Takifugu rubripes	78.26	0.00e+00	737.00
IUUC-Tsy-119552	Tarsius syrichta	99.66	1.00e-174	607.00
IUUC-Tca-121616	Theobroma cacao	38.10	1.00e-30	128.00
IUUC-Tae-123681	Triticum aestivum	42.17	3.00e-30	125.00
IUUC-Tur-126480	Triticum urartu	42.17	2.00e-30	127.00
IUUC-Tbe-127902	Tupaia belangeri	83.40	0.00e+00	666.00
IUUC-Ttr-129278	Tursiops truncatus	98.02	0.00e+00	698.00
IUUC-Vpa-130741	Vicugna pacos	90.37	0.00e+00	839.00
IUUC-Vvi-131437	Vitis vinifera	40.30	2.00e-29	124.00
IUUC-Xtr-132247	Xenopus tropicalis	62.50	4.00e-157	549.00
IUUC-Xma-134277	Xiphophorus maculatus	78.91	0.00e+00	800.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence