iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067641

Ensembl Protein ID

ENSMLUP00000010640.2

UniProt Accession

G1PIU0; G1PIU0_MYOLU

Genbank Protein ID

ENSMLUP00000010640

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02007658

Gene Name

WDFY3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000011620.2	ENSMLUT00000011682.2	ENSMLUP00000010640.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-11	43.9	3125	3156

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtc..laf.sdtllvsGsdDgtikvWDl 30
           gHtd vtc   +f   +++vsGs+D t+ +WDl
   Q: 3125 GHTDTVTCatASFaY-HIIVSGSRDRTCIIWDL 3156
           8*******5424642.79**************8 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MNMVKRIMGR PRQEECSPQD NALGLMHLRR LFTELCHPPR HMTQKEQEEK LYMMLPVFNR 60
VFGNAPPNTM TEKFSDLLQF TTQVSRLMVT EIRRRASNKS TEAASRAIVQ FLEINQSEEA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAACATGG TGAAGAGGAT CATGGGGCGC CCAAGGCAGG AGGAGTGCAG CCCGCAGGAC 60
AACGCCTTGG GACTGATGCA CCTCCGCCGG CTCTTCACTG AGTTGTGCCA TCCTCCTCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000409--BEACH_dom
IPR013320--ConA-like_dom
IPR031570--DUF4704
IPR023362--PH-BEACH_dom
IPR011993--PH_dom-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50197--BEACH
PS51783--PH_BEACH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS50178--ZF_FYVE

Pfam

PF02138--Beach
PF15787--DUF4704
PF01363--FYVE
PF14844--PH_BEACH
PF00400--WD40

SMART

SM01026--Beach
SM00064--FYVE
SM00320--WD40

Gene Ontology

GO:0034274--C:Atg12-Atg5-Atg16 complex
GO:0005829--C:cytosol
GO:0097635--C:extrinsic component of autophagosome membrane
GO:0016234--C:inclusion body
GO:0005635--C:nuclear envelope
GO:0005730--C:nucleolus
GO:0005886--C:plasma membrane
GO:0016605--C:PML body
GO:0005545--F:1-phosphatidylinositol binding
GO:0003831--F:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
GO:0046872--F:metal ion binding
GO:0035973--P:aggrephagy

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000317	Aegilops tauschii	33.09	6.00e-176	613.00
IUUC-Aml-002094	Ailuropoda melanoleuca	97.48	0.00e+00	6913.00
IUUC-Atr-002879	Amborella trichopoda	37.54	3.00e-174	607.00
IUUC-Apl-003581	Anas platyrhynchos	91.29	0.00e+00	4992.00
IUUC-Aca-005386	Anolis carolinensis	91.02	0.00e+00	6544.00
IUUC-Aly-006119	Arabidopsis lyrata	34.08	2.00e-178	621.00
IUUC-Ath-007645	Arabidopsis thaliana	46.10	6.00e-169	590.00
IUUC-Afu-009064	Aspergillus fumigatus	35.22	3.00e-165	577.00
IUUC-Ani-009310	Aspergillus nidulans	35.95	8.00e-159	556.00
IUUC-Aor-010079	Aspergillus oryzae	36.09	1.00e-164	575.00
IUUC-Ame-011607	Astyanax mexicanus	81.66	0.00e+00	5651.00
IUUC-Bta-012997	Bos taurus	96.97	0.00e+00	6812.00
IUUC-Bci-013784	Botrytis cinerea	40.42	1.00e-160	561.00
IUUC-Bdi-015031	Brachypodium distachyon	33.66	1.00e-174	608.00
IUUC-Bol-016599	Brassica oleracea	47.04	1.00e-162	568.00
IUUC-Bra-017709	Brassica rapa	46.88	2.00e-162	568.00
IUUC-Cja-019272	Callithrix jacchus	96.89	0.00e+00	6857.00
IUUC-Cfa-020073	Canis familiaris	97.22	0.00e+00	6858.00
IUUC-Cpo-021455	Cavia porcellus	95.05	0.00e+00	6724.00
IUUC-Csa-023097	Chlorocebus sabaeus	96.05	0.00e+00	6847.00
IUUC-Cgl-026670	Colletotrichum gloeosporioides	34.62	5.00e-142	500.00
IUUC-Dre-027703	Danio rerio	83.54	0.00e+00	5896.00
IUUC-Dno-029515	Dasypus novemcinctus	98.52	0.00e+00	963.00
IUUC-Dor-030567	Dipodomys ordii	86.35	0.00e+00	2089.00
IUUC-Dme-031959	Drosophila melanogaster	47.30	0.00e+00	2768.00
IUUC-Ete-032373	Echinops telfairi	87.59	0.00e+00	3600.00
IUUC-Eca-033575	Equus caballus	97.22	0.00e+00	6907.00
IUUC-Eeu-034853	Erinaceus europaeus	85.59	0.00e+00	2230.00
IUUC-Fca-036304	Felis catus	97.45	0.00e+00	6860.00
IUUC-Fal-037019	Ficedula albicollis	92.27	0.00e+00	6596.00
IUUC-Fox-038015	Fusarium oxysporum	33.73	5.00e-150	525.00
IUUC-Fso-038249	Fusarium solani	29.96	1.00e-147	518.00
IUUC-Gmo-039503	Gadus morhua	78.64	0.00e+00	5588.00
IUUC-Ggr-039900	Gaeumannomyces graminis	39.45	1.00e-149	525.00
IUUC-Gga-041220	Gallus gallus	32.86	0.00e+00	1113.00
IUUC-Gac-041618	Gasterosteus aculeatus	81.42	0.00e+00	5783.00
IUUC-Gma-043242	Glycine max	34.07	3.00e-176	614.00
IUUC-Ggo-044679	Gorilla gorilla	94.49	0.00e+00	6665.00
IUUC-Hsa-046586	Homo sapiens	97.22	0.00e+00	6900.00
IUUC-Hvu-047814	Hordeum vulgare	33.76	1.00e-177	619.00
IUUC-Itr-048396	Ictidomys tridecemlineatus	96.07	0.00e+00	5635.00
IUUC-Lpe-050828	Leersia perrieri	34.35	2.00e-179	624.00
IUUC-Loc-052434	Lepisosteus oculatus	86.48	0.00e+00	6162.00
IUUC-Lma-053017	Leptosphaeria maculans	28.79	4.00e-134	473.00
IUUC-Laf-054408	Loxodonta africana	96.40	0.00e+00	6855.00
IUUC-Mcc-055652	Macaca mulatta	97.03	0.00e+00	6898.00
IUUC-Meu-056743	Macropus eugenii	79.96	0.00e+00	2791.00
IUUC-Mor-057120	Magnaporthe oryzae	34.84	4.00e-160	560.00
IUUC-Mtr-058732	Medicago truncatula	37.90	2.00e-177	618.00
IUUC-Mla-058974	Melampsora laricipopulina	32.95	1.00e-138	489.00
IUUC-Mvi-060546	Microbotryum violaceum	30.74	8.00e-158	552.00
IUUC-Mmr-061760	Microcebus murinus	90.97	0.00e+00	6327.00
IUUC-Mdo-062645	Monodelphis domestica	94.11	0.00e+00	6665.00
IUUC-Mmu-063588	Mus musculus	95.61	0.00e+00	6875.00
IUUC-Mac-064551	Musa acuminata	38.30	6.00e-172	599.00
IUUC-Mpu-066073	Mustela putorius furo	97.42	0.00e+00	6860.00
IUUC-Nfi-068471	Neosartorya fischeri	36.91	2.00e-165	578.00
IUUC-Nle-070009	Nomascus leucogenys	96.88	0.00e+00	6870.00
IUUC-Opr-070689	Ochotona princeps	92.71	0.00e+00	5892.00
IUUC-Ont-071427	Oreochromis niloticus	82.51	0.00e+00	5785.00
IUUC-Oan-073118	Ornithorhynchus anatinus	86.97	0.00e+00	6083.00
IUUC-Ocu-074702	Oryctolagus cuniculus	97.11	0.00e+00	6918.00
IUUC-Oba-075831	Oryza barthii	33.80	1.00e-177	619.00
IUUC-Obr-076728	Oryza brachyantha	33.95	8.00e-177	616.00
IUUC-Ogl-077922	Oryza glaberrima	33.80	2.00e-177	618.00
IUUC-Ogu-079001	Oryza glumaepatula	33.39	2.00e-173	604.00
IUUC-Oin-079929	Oryza indica	37.00	2.00e-164	573.00
IUUC-Olo-080662	Oryza longistaminata	33.96	1.00e-177	619.00
IUUC-Ome-081733	Oryza meridionalis	33.96	3.00e-178	620.00
IUUC-Oni-082641	Oryza nivara	33.88	2.00e-177	617.00
IUUC-Opu-083564	Oryza punctata	34.40	2.00e-178	621.00
IUUC-Oru-084403	Oryza rufipogon	33.88	5.00e-177	617.00
IUUC-Osa-085957	Oryza sativa	36.21	5.00e-46	178.00
IUUC-Ola-086856	Oryzias latipes	79.37	0.00e+00	5612.00
IUUC-Oga-088908	Otolemur garnettii	97.06	0.00e+00	3069.00
IUUC-Oar-089625	Ovis aries	96.10	0.00e+00	6737.00
IUUC-Ptr-091209	Pan troglodytes	97.11	0.00e+00	6896.00
IUUC-Pan-092751	Papio anubis	96.83	0.00e+00	6878.00
IUUC-Psi-092951	Pelodiscus sinensis	92.32	0.00e+00	6647.00
IUUC-Ppa-095361	Physcomitrella patens	35.27	0.00e+00	633.00
IUUC-Pfo-097102	Poecilia formosa	80.80	0.00e+00	5741.00
IUUC-Pab-098485	Pongo abelii	96.29	0.00e+00	6843.00
IUUC-Pop-099807	Populus trichocarpa	37.32	4.00e-180	627.00
IUUC-Pca-100146	Procavia capensis	90.20	0.00e+00	1474.00
IUUC-Ppe-101277	Prunus persica	37.69	0.00e+00	637.00
IUUC-Pva-102502	Pteropus vampyrus	87.44	0.00e+00	3254.00
IUUC-Ptt-103873	Puccinia triticina	40.35	1.00e-92	336.00
IUUC-Rno-105592	Rattus norvegicus	94.34	0.00e+00	6777.00
IUUC-Sha-106751	Sarcophilus harrisii	83.21	0.00e+00	5816.00
IUUC-Sja-107759	Schizosaccharomyces japonicus	39.31	8.00e-151	529.00
IUUC-Spo-108108	Schizosaccharomyces pombe	40.16	2.00e-154	541.00
IUUC-Ssl-108524	Sclerotinia sclerotiorum	37.40	2.00e-161	563.00
IUUC-Smo-109485	Selaginella moellendorffii	33.19	0.00e+00	650.00
IUUC-Sit-110811	Setaria italica	41.96	4.00e-173	603.00
IUUC-Sly-110936	Solanum lycopersicum	35.62	4.00e-179	624.00
IUUC-Sar-113013	Sorex araneus	81.71	0.00e+00	1390.00
IUUC-Sbi-114421	Sorghum bicolor	42.72	4.00e-174	607.00
IUUC-Sre-115137	Sporisorium reilianum	32.31	1.00e-132	468.00
IUUC-Ssc-116100	Sus scrofa	96.52	0.00e+00	6868.00
IUUC-Tgu-117182	Taeniopygia guttata	91.88	0.00e+00	6559.00
IUUC-Tru-117859	Takifugu rubripes	81.96	0.00e+00	5705.00
IUUC-Tsy-119315	Tarsius syrichta	96.68	0.00e+00	4279.00
IUUC-Tni-120784	Tetraodon nigroviridis	80.92	0.00e+00	5622.00
IUUC-Tca-121423	Theobroma cacao	37.78	1.00e-175	612.00
IUUC-Tre-121988	Trichoderma reesei	36.47	8.00e-156	546.00
IUUC-Tvi-122476	Trichoderma virens	36.35	3.00e-157	550.00
IUUC-Tur-126221	Triticum urartu	33.47	9.00e-177	616.00
IUUC-Tme-126944	Tuber melanosporum	40.24	4.00e-156	546.00
IUUC-Tbe-127827	Tupaia belangeri	90.51	0.00e+00	2749.00
IUUC-Ttr-128368	Tursiops truncatus	97.08	0.00e+00	6910.00
IUUC-Vda-129813	Verticillium dahliae	40.11	4.00e-150	527.00
IUUC-Vpa-130252	Vicugna pacos	96.89	0.00e+00	4410.00
IUUC-Vvi-131663	Vitis vinifera	38.39	1.00e-177	619.00
IUUC-Xtr-132689	Xenopus tropicalis	86.83	0.00e+00	6311.00
IUUC-Xma-133273	Xiphophorus maculatus	82.57	0.00e+00	4823.00
IUUC-Zma-135580	Zea mays	43.28	8.00e-173	603.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence