iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092448

Ensembl Protein ID

ENSPANP00000006336.1

UniProt Accession

A0A096N1Z5; A0A096N1Z5_PAPAN

Genbank Protein ID

ENSPANP00000006336

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01033128

Gene Name

TRIM33

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000016076.1	ENSPANT00000027924.1	ENSPANP00000006336.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	3.20e-09	36.9	881	926
E3 activity/RING/RING	3.50e-06	27.5	125	185

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C+vC++gg+    l++CekC ++fH +C+ ++   ++p+ + wiC+ Cr+
   Q: 881  DWCAVCQNGGD----LLCCEKCPKVFHLTCHVPT-LLSFPSGD-WICTFCRD 926
           79*********....*******************.*******7.******85 PP

E3 activity/RING/RING

   S: 1    CaiCledf....kdgplvlpCgHvfhadCl...qkw........pglknssskefrCPlCr 46
           Ca+C++++    + +p++lpC H f++ Cl   ++          +   ++ + +rCP+Cr
   Q: 125  CAVCQQSLqsrrEAEPKLLPCLHSFCLRCLpepERQlsvpipggSNGDIQQVGVIRCPVCR 185
           ******999888556***************88844468888666555556667779****8 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MAENKGGGEA ESGGGGSGSA PVTAGAAGPA AQEAEPPLTA VLVEEEEEEG GRAGAEGGAA 60
GPDDGGVAAA SSGSAQAASS PAASVGPAVP GGAVSTPAPA PASAPAPGPS AGPPPGPPAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAAA ACAAAGGCGG TGGCGAGGCT GAGAGCGGCG GCGGGGGCAG CGGCAGCGCG 60
CCGGTAACTG CTGGGGCCGC CGGGCCCGCG GCGCAGGAGG CGGAGCCGCC TCTCACCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR019786--Zinc_finger_PHD-type_CS
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR00503--BROMODOMAIN

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD
SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0030514--P:negative regulation of BMP signaling pathway
GO:0016567--P:protein ubiquitination
GO:0017015--P:regulation of transforming growth factor beta receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002364	Ailuropoda melanoleuca	95.84	0.00e+00	1741.00
IUUC-Apl-003894	Anas platyrhynchos	93.49	0.00e+00	1620.00
IUUC-Aca-004658	Anolis carolinensis	91.56	0.00e+00	1580.00
IUUC-Ame-011619	Astyanax mexicanus	61.05	0.00e+00	1060.00
IUUC-Bta-013341	Bos taurus	95.13	0.00e+00	1703.00
IUUC-Cja-018733	Callithrix jacchus	96.92	0.00e+00	1771.00
IUUC-Cfa-020725	Canis familiaris	96.68	0.00e+00	1716.00
IUUC-Cpo-021833	Cavia porcellus	97.02	0.00e+00	1736.00
IUUC-Csa-023040	Chlorocebus sabaeus	97.52	0.00e+00	1719.00
IUUC-Cho-024934	Choloepus hoffmanni	93.59	0.00e+00	1623.00
IUUC-Cin-025200	Ciona intestinalis	31.97	1.00e-45	178.00
IUUC-Csv-026278	Ciona savignyi	47.25	4.00e-20	91.30
IUUC-Dre-027797	Danio rerio	72.61	3.00e-172	599.00
IUUC-Dno-028955	Dasypus novemcinctus	95.93	0.00e+00	1799.00
IUUC-Dme-032143	Drosophila melanogaster	31.98	3.00e-45	177.00
IUUC-Ete-032728	Echinops telfairi	96.06	0.00e+00	928.00
IUUC-Eca-033573	Equus caballus	95.64	0.00e+00	1717.00
IUUC-Eeu-035138	Erinaceus europaeus	82.19	0.00e+00	823.00
IUUC-Fca-035776	Felis catus	96.53	0.00e+00	1627.00
IUUC-Fal-037583	Ficedula albicollis	92.49	0.00e+00	1641.00
IUUC-Gmo-039353	Gadus morhua	63.14	0.00e+00	667.00
IUUC-Gga-040874	Gallus gallus	93.81	0.00e+00	1722.00
IUUC-Gac-041689	Gasterosteus aculeatus	56.37	0.00e+00	1112.00
IUUC-Ggo-045151	Gorilla gorilla	96.51	0.00e+00	1331.00
IUUC-Hsa-046169	Homo sapiens	97.32	0.00e+00	1715.00
IUUC-Itr-048377	Ictidomys tridecemlineatus	98.18	0.00e+00	753.00
IUUC-Lch-050411	Latimeria chalumnae	83.62	0.00e+00	1389.00
IUUC-Loc-051992	Lepisosteus oculatus	73.37	0.00e+00	1303.00
IUUC-Laf-054552	Loxodonta africana	95.91	0.00e+00	1650.00
IUUC-Mcc-055744	Macaca mulatta	97.42	0.00e+00	1717.00
IUUC-Meu-056647	Macropus eugenii	99.15	0.00e+00	707.00
IUUC-Mga-059589	Meleagris gallopavo	93.69	0.00e+00	974.00
IUUC-Mmr-060727	Microcebus murinus	97.11	0.00e+00	1747.00
IUUC-Mdo-063029	Monodelphis domestica	94.64	0.00e+00	1749.00
IUUC-Mmu-064033	Mus musculus	94.84	0.00e+00	1758.00
IUUC-Mpu-066679	Mustela putorius furo	96.23	0.00e+00	1732.00
IUUC-Mlu-067286	Myotis lucifugus	95.48	0.00e+00	1628.00
IUUC-Nle-069156	Nomascus leucogenys	97.02	0.00e+00	1709.00
IUUC-Opr-070309	Ochotona princeps	87.35	0.00e+00	1278.00
IUUC-Ont-071586	Oreochromis niloticus	55.77	0.00e+00	1053.00
IUUC-Oan-073205	Ornithorhynchus anatinus	96.44	0.00e+00	1470.00
IUUC-Ocu-074667	Oryctolagus cuniculus	93.48	0.00e+00	1616.00
IUUC-Ola-086481	Oryzias latipes	67.23	5.00e-165	575.00
IUUC-Oga-089101	Otolemur garnettii	95.93	0.00e+00	1731.00
IUUC-Oar-090167	Ovis aries	95.83	0.00e+00	1743.00
IUUC-Ptr-090901	Pan troglodytes	97.42	0.00e+00	1717.00
IUUC-Psi-093657	Pelodiscus sinensis	93.89	0.00e+00	1503.00
IUUC-Pma-094506	Petromyzon marinus	65.91	1.00e-50	191.00
IUUC-Pfo-097104	Poecilia formosa	69.15	5.00e-160	558.00
IUUC-Pab-097704	Pongo abelii	97.32	0.00e+00	1753.00
IUUC-Pca-101001	Procavia capensis	84.47	0.00e+00	650.00
IUUC-Pva-102733	Pteropus vampyrus	91.58	0.00e+00	1562.00
IUUC-Rno-105512	Rattus norvegicus	95.53	0.00e+00	1751.00
IUUC-Sha-107423	Sarcophilus harrisii	93.53	0.00e+00	1625.00
IUUC-Sar-113181	Sorex araneus	86.32	1.00e-143	504.00
IUUC-Ssc-116330	Sus scrofa	91.19	0.00e+00	1523.00
IUUC-Tgu-117388	Taeniopygia guttata	77.39	0.00e+00	1271.00
IUUC-Tru-118728	Takifugu rubripes	57.67	0.00e+00	991.00
IUUC-Tsy-119053	Tarsius syrichta	94.92	0.00e+00	1046.00
IUUC-Tni-120279	Tetraodon nigroviridis	47.41	9.00e-167	580.00
IUUC-Tbe-127573	Tupaia belangeri	90.21	0.00e+00	842.00
IUUC-Ttr-128594	Tursiops truncatus	96.03	0.00e+00	1738.00
IUUC-Vpa-130619	Vicugna pacos	89.76	0.00e+00	1092.00
IUUC-Xtr-132837	Xenopus tropicalis	86.21	0.00e+00	1509.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence