iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071844

Ensembl Protein ID

ENSONIP00000020588.1

UniProt Accession

I3KHJ3; I3KHJ3_ORENI

Genbank Protein ID

ENSONIP00000020588

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AERX01007414

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000016351.1	ENSONIT00000020606.1	ENSONIP00000020588.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.20e-47	158.1	260	309

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            +ly++ a + +eL +  Gd ++++   + + gWl+g  + +g+rG+fP+ Fv+
   Q: 260  VALYEFRAMEPGELDFDVGDRIRIV--GTLEDGWLEG--QVRGQRGIFPHRFVK 309
           69***********************..88899*****..7************97 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MEAGSVVRAV FEFLPSVSEE LPLFTGDVIE VLSVVDEFWL LGNKDGVTGQ FPSTFVEEVT 60
IPSTKPGDRL YVCINDFSSA EPGNLSLKRG DVVVGEAGGS VDLGEIWQRG CNVWGARGLF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTAGCTGA TTTCAGGAGT AAAAATATCA AAATGTGTTT AGCAAAATGT AAACTAATGG 60
GCTTCTGTAC TGAAACAGGC CCCAATGGTT ATCACGTATC TATTTATCTA TAACGTGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS00741--DH_1
PS50010--DH_2
PS50002--SH3

Pfam

PF03114--BAR
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0060271--P:cilium assembly
GO:0035556--P:intracellular signal transduction
GO:0001822--P:kidney development
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002128	Ailuropoda melanoleuca	60.66	0.00e+00	815.00
IUUC-Apl-003934	Anas platyrhynchos	63.13	0.00e+00	838.00
IUUC-Aca-005005	Anolis carolinensis	62.06	0.00e+00	852.00
IUUC-Ame-011361	Astyanax mexicanus	71.24	0.00e+00	1162.00
IUUC-Bta-013210	Bos taurus	56.28	0.00e+00	886.00
IUUC-Cel-018396	Caenorhabditis elegans	24.78	1.00e-29	126.00
IUUC-Cja-019104	Callithrix jacchus	59.43	0.00e+00	788.00
IUUC-Cfa-020960	Canis familiaris	56.37	0.00e+00	902.00
IUUC-Cpo-022440	Cavia porcellus	61.75	0.00e+00	836.00
IUUC-Csa-023391	Chlorocebus sabaeus	61.16	2.00e-106	381.00
IUUC-Cho-024795	Choloepus hoffmanni	46.79	0.00e+00	693.00
IUUC-Cin-025137	Ciona intestinalis	34.31	3.00e-29	121.00
IUUC-Dre-027932	Danio rerio	69.34	0.00e+00	1157.00
IUUC-Dno-029750	Dasypus novemcinctus	55.35	0.00e+00	907.00
IUUC-Dor-031109	Dipodomys ordii	61.31	0.00e+00	834.00
IUUC-Ete-032660	Echinops telfairi	56.45	0.00e+00	678.00
IUUC-Eca-033433	Equus caballus	56.24	0.00e+00	911.00
IUUC-Eeu-034929	Erinaceus europaeus	61.98	3.00e-125	443.00
IUUC-Fca-035859	Felis catus	56.30	0.00e+00	917.00
IUUC-Fal-036653	Ficedula albicollis	50.49	0.00e+00	898.00
IUUC-Gmo-038948	Gadus morhua	76.16	0.00e+00	1021.00
IUUC-Gga-040279	Gallus gallus	61.92	0.00e+00	806.00
IUUC-Gac-041641	Gasterosteus aculeatus	75.08	0.00e+00	1319.00
IUUC-Ggo-044900	Gorilla gorilla	28.95	1.00e-71	264.00
IUUC-Hsa-046063	Homo sapiens	62.16	0.00e+00	839.00
IUUC-Itr-049071	Ictidomys tridecemlineatus	55.14	0.00e+00	898.00
IUUC-Lch-049865	Latimeria chalumnae	56.91	0.00e+00	739.00
IUUC-Loc-051754	Lepisosteus oculatus	67.02	0.00e+00	1197.00
IUUC-Laf-054037	Loxodonta africana	56.27	0.00e+00	956.00
IUUC-Mcc-055002	Macaca mulatta	56.47	0.00e+00	922.00
IUUC-Meu-056420	Macropus eugenii	52.78	0.00e+00	755.00
IUUC-Mor-057139	Magnaporthe oryzae	25.43	5.00e-12	67.00
IUUC-Mga-059868	Meleagris gallopavo	63.08	0.00e+00	798.00
IUUC-Mmr-060767	Microcebus murinus	56.09	0.00e+00	931.00
IUUC-Mdo-061939	Monodelphis domestica	55.77	0.00e+00	876.00
IUUC-Mmu-063980	Mus musculus	53.43	0.00e+00	845.00
IUUC-Mpu-065913	Mustela putorius furo	56.36	0.00e+00	935.00
IUUC-Mlu-067340	Myotis lucifugus	54.74	0.00e+00	895.00
IUUC-Nle-069343	Nomascus leucogenys	62.02	0.00e+00	837.00
IUUC-Opr-070694	Ochotona princeps	56.62	0.00e+00	934.00
IUUC-Oan-073605	Ornithorhynchus anatinus	65.67	2.00e-23	103.00
IUUC-Ocu-074406	Oryctolagus cuniculus	56.03	0.00e+00	936.00
IUUC-Ola-087343	Oryzias latipes	68.33	0.00e+00	822.00
IUUC-Oga-088847	Otolemur garnettii	56.43	0.00e+00	917.00
IUUC-Oar-089817	Ovis aries	59.89	0.00e+00	789.00
IUUC-Ptr-090508	Pan troglodytes	28.95	1.00e-71	264.00
IUUC-Pan-092104	Papio anubis	61.89	0.00e+00	833.00
IUUC-Psi-094045	Pelodiscus sinensis	63.49	2.00e-63	237.00
IUUC-Pma-094663	Petromyzon marinus	46.01	2.00e-139	490.00
IUUC-Pfo-096714	Poecilia formosa	71.31	0.00e+00	1273.00
IUUC-Pab-097918	Pongo abelii	61.89	0.00e+00	836.00
IUUC-Pca-101096	Procavia capensis	52.09	7.00e-124	439.00
IUUC-Pva-102490	Pteropus vampyrus	57.00	0.00e+00	942.00
IUUC-Rno-105908	Rattus norvegicus	53.48	0.00e+00	865.00
IUUC-Sha-107509	Sarcophilus harrisii	55.43	0.00e+00	915.00
IUUC-Ssc-115250	Sus scrofa	55.84	0.00e+00	882.00
IUUC-Tru-118279	Takifugu rubripes	72.04	0.00e+00	1291.00
IUUC-Tni-120459	Tetraodon nigroviridis	79.97	0.00e+00	964.00
IUUC-Tbe-127753	Tupaia belangeri	39.11	1.00e-93	338.00
IUUC-Ttr-129096	Tursiops truncatus	56.09	0.00e+00	907.00
IUUC-Vpa-130643	Vicugna pacos	58.81	0.00e+00	702.00
IUUC-Xtr-131979	Xenopus tropicalis	58.46	0.00e+00	1028.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence