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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Ath-007290
UUCD1 version UUC-ArT-01662
Ensembl Protein ID AT5G23540.1
UniProt Accession Q9LT08; Q0WQQ6; Q8LD11; PSDE_ARATH
Genbank Protein ID AAP86670.1; AAP86671.1; AAP86672.1; BAA97246.1; AED93181.1; AAL49768.1; AAM14268.1; BAF00543.1; AAM64349.1
Protein Name 26S proteasome non-ATPase regulatory subunit 14 homolog; 26S proteasome regulatory subunit RPN11
Genbank Nucleotide ID AY230843; AY230844; AY230845; AB025633; CP002688; AY070073; AY091329; AK228634; AY086277
Gene Name RPN11; At5g23540; MQM1.19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT5G23540 AT5G23540.1 AT5G23540.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
Protein-protein Interaction
PINAHINTMentha
Post-translational Modifications (PTMs)
dbPPTdbPTM
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/JAMM 8.90e-08 32.8 112 125
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/JAMM
   S: 1    HSHPgftcwlSsVD 14
           HSHPgf+cwlS+VD
   Q: 112  HSHPGFGCWLSGVD 125
           *************9 PP
   
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description


     Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear (By similarity).
 Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear (By similarity).
Protein Sequence
(Fasta)
MERLQRIFGA GGGLGHASPD SPTLDTSEQV YISSLALLKM LKHGRAGVPM EVMGLMLGEF 60
VDEYTVRVVD VFAMPQSGTG VSVEAVDHVF QTNMLDMLKQ TGRPEMVVGW YHSHPGFGCW 120
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Protein Fasta Sequence


>IUUC-Ath-007290|DUB,JAMM|Arabidopsis thaliana
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Nucleotide Sequence
(Fasta)
CCTAATCGAG TAATTCGATC CATCTTCGTC TGTCTTGTTA ACAAAGAAAA CTGAGAAAGG 60
TTTTCTTATA AGATCCCATT CTTGTAGCAA AAACCCAGAA GAACAAACTT TCGAAGAAGA 120
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Nucleotide Fasta Sequence


>IUUC-Ath-007290|DUB,JAMM|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0482--Metalloprotease
KW-0645--Protease
KW-0647--Proteasome
KW-1185--Reference proteome
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
Interpro

IPR000555--JAMM/MPN+_dom
IPR024969--Rpn11/EIF3F_C
Pfam

PF01398--JAB
PF13012--MitMem_reg
SMART

SM00232--JAB_MPN
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000502--C:proteasome complex
GO:0046872--F:metal ion binding
GO:0008237--F:metallopeptidase activity
GO:0030163--P:protein catabolic process
GO:0009651--P:response to salt stress
KEGG ath:AT5G23540
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000544 Aegilops tauschii 92.21 1.00e-159 555.00
IUUC-Aml-001416 Ailuropoda melanoleuca 82.35 2.00e-144 504.00
IUUC-Atr-002629 Amborella trichopoda 93.83 8.00e-158 548.00
IUUC-Apl-004046 Anas platyrhynchos 81.48 1.00e-145 508.00
IUUC-Aca-005228 Anolis carolinensis 82.35 1.00e-144 504.00
IUUC-Aly-005457 Arabidopsis lyrata 99.68 5.00e-173 598.00
IUUC-Ago-007866 Ashbya gossypii 62.26 2.00e-109 388.00
IUUC-Acl-008338 Aspergillus clavatus 70.98 2.00e-106 377.00
IUUC-Afl-008431 Aspergillus flavus 73.08 1.00e-121 428.00
IUUC-Afu-008909 Aspergillus fumigatus 72.38 1.00e-115 408.00
IUUC-Ani-009174 Aspergillus nidulans 68.61 2.00e-121 427.00
IUUC-Ang-009854 Aspergillus niger 69.38 5.00e-122 429.00
IUUC-Aor-009942 Aspergillus oryzae 73.08 3.00e-121 427.00
IUUC-Ate-010377 Aspergillus terreus 69.58 2.00e-121 428.00
IUUC-Ame-011628 Astyanax mexicanus 82.76 5.00e-131 459.00
IUUC-Bgr-012263 Blumeria graminis 67.42 2.00e-111 394.00
IUUC-Bta-012375 Bos taurus 82.35 2.00e-144 504.00
IUUC-Bci-013850 Botrytis cinerea 72.73 3.00e-112 397.00
IUUC-Bdi-014488 Brachypodium distachyon 93.83 6.00e-157 545.00
IUUC-Bol-016172 Brassica oleracea 100.00 6.00e-174 602.00
IUUC-Bra-017926 Brassica rapa 100.00 6.00e-174 602.00
IUUC-Cel-018247 Caenorhabditis elegans 71.72 9.00e-125 438.00
IUUC-Cja-019210 Callithrix jacchus 80.67 3.00e-145 506.00
IUUC-Cfa-020926 Canis familiaris 81.31 3.00e-141 493.00
IUUC-Cpo-021572 Cavia porcellus 82.35 2.00e-144 504.00
IUUC-Cre-022925 Chlamydomonas reinhardtii 80.28 2.00e-134 470.00
IUUC-Csa-023496 Chlorocebus sabaeus 82.35 2.00e-144 504.00
IUUC-Cho-024525 Choloepus hoffmanni 76.69 3.00e-133 467.00
IUUC-Cin-025492 Ciona intestinalis 80.07 2.00e-142 498.00
IUUC-Cgl-026493 Colletotrichum gloeosporioides 69.40 6.00e-101 359.00
IUUC-Cne-026785 Cryptococcus neoformans 68.84 7.00e-118 416.00
IUUC-Cme-027105 Cyanidioschyzon merolae 60.58 2.00e-104 371.00
IUUC-Dre-028788 Danio rerio 82.35 2.00e-144 504.00
IUUC-Dno-029058 Dasypus novemcinctus 78.32 1.00e-145 508.00
IUUC-Dor-031015 Dipodomys ordii 74.74 5.00e-126 442.00
IUUC-Dse-031242 Dothistroma septosporum 72.98 9.00e-123 432.00
IUUC-Dme-031668 Drosophila melanogaster 76.77 1.00e-144 504.00
IUUC-Ete-033146 Echinops telfairi 74.44 1.00e-116 411.00
IUUC-Eca-033734 Equus caballus 82.35 2.00e-144 504.00
IUUC-Eeu-035168 Erinaceus europaeus 63.03 2.00e-81 294.00
IUUC-Fca-036426 Felis catus 82.35 2.00e-144 504.00
IUUC-Fal-036954 Ficedula albicollis 82.35 1.00e-144 504.00
IUUC-Fox-037838 Fusarium oxysporum 70.34 2.00e-120 424.00
IUUC-Fso-038374 Fusarium solani 71.53 4.00e-119 420.00
IUUC-Gmo-038918 Gadus morhua 82.35 2.00e-144 503.00
IUUC-Ggr-039954 Gaeumannomyces graminis 68.73 2.00e-122 431.00
IUUC-Gga-040377 Gallus gallus 82.35 1.00e-144 504.00
IUUC-Gac-042386 Gasterosteus aculeatus 79.61 2.00e-147 513.00
IUUC-Gma-042811 Glycine max 95.15 3.00e-162 563.00
IUUC-Ggo-044916 Gorilla gorilla 82.35 2.00e-144 504.00
IUUC-Hsa-045865 Homo sapiens 82.35 2.00e-144 504.00
IUUC-Hvu-047188 Hordeum vulgare 91.88 2.00e-160 557.00
IUUC-Itr-048154 Ictidomys tridecemlineatus 86.67 2.00e-91 326.00
IUUC-Kpa-049128 Komagataella pastoris 72.62 4.00e-113 400.00
IUUC-Lch-050167 Latimeria chalumnae 75.00 3.00e-134 470.00
IUUC-Lpe-050688 Leersia perrieri 93.18 2.00e-160 558.00
IUUC-Loc-052888 Lepisosteus oculatus 82.35 1.00e-144 504.00
IUUC-Lma-052962 Leptosphaeria maculans 67.86 4.00e-120 423.00
IUUC-Laf-053949 Loxodonta africana 82.35 2.00e-144 504.00
IUUC-Mcc-055279 Macaca mulatta 81.05 2.00e-140 491.00
IUUC-Meu-055956 Macropus eugenii 74.39 1.00e-126 444.00
IUUC-Mor-057166 Magnaporthe oryzae 69.16 3.00e-113 400.00
IUUC-Mpo-057344 Magnaporthe poae 68.40 2.00e-122 431.00
IUUC-Mtr-057857 Medicago truncatula 95.47 2.00e-163 566.00
IUUC-Mla-058938 Melampsora laricipopulina 74.75 2.00e-134 470.00
IUUC-Mga-060093 Meleagris gallopavo 82.35 1.00e-144 504.00
IUUC-Mvi-060565 Microbotryum violaceum 73.94 3.00e-127 446.00
IUUC-Mmr-060899 Microcebus murinus 82.44 5.00e-140 489.00
IUUC-Mdo-062175 Monodelphis domestica 82.35 7.00e-145 505.00
IUUC-Mmu-063416 Mus musculus 82.35 2.00e-144 504.00
IUUC-Mac-064901 Musa acuminata 93.18 3.00e-162 563.00
IUUC-Mpu-065946 Mustela putorius furo 82.35 2.00e-144 504.00
IUUC-Mlu-067835 Myotis lucifugus 79.87 6.00e-145 505.00
IUUC-Nfi-068279 Neosartorya fischeri 72.38 1.00e-115 408.00
IUUC-Ncr-068821 Neurospora crassa 72.60 4.00e-112 397.00
IUUC-Nle-069212 Nomascus leucogenys 82.35 2.00e-144 504.00
IUUC-Opr-070928 Ochotona princeps 53.69 7.00e-67 246.00
IUUC-Ont-072135 Oreochromis niloticus 82.35 1.00e-144 504.00
IUUC-Oan-072755 Ornithorhynchus anatinus 82.35 7.00e-145 505.00
IUUC-Ocu-074433 Oryctolagus cuniculus 82.95 3.00e-133 466.00
IUUC-Oba-075351 Oryza barthii 93.18 2.00e-155 541.00
IUUC-Obr-076756 Oryza brachyantha 93.18 2.00e-160 556.00
IUUC-Ogl-077831 Oryza glaberrima 93.18 2.00e-155 541.00
IUUC-Ogu-078028 Oryza glumaepatula 93.18 2.00e-155 541.00
IUUC-Oin-080184 Oryza indica 92.86 1.00e-159 554.00
IUUC-Olo-080580 Oryza longistaminata 95.73 2.00e-150 524.00
IUUC-Ome-081739 Oryza meridionalis 90.54 2.00e-153 534.00
IUUC-Oni-082861 Oryza nivara 93.18 2.00e-155 541.00
IUUC-Opu-083352 Oryza punctata 93.18 2.00e-155 541.00
IUUC-Oru-084210 Oryza rufipogon 93.18 2.00e-155 541.00
IUUC-Osa-086114 Oryza sativa 93.18 2.00e-155 541.00
IUUC-Ola-087317 Oryzias latipes 82.35 1.00e-144 504.00
IUUC-Olu-087889 Ostreococcus lucimarinus 78.55 5.00e-136 476.00
IUUC-Oga-088032 Otolemur garnettii 81.42 4.00e-145 506.00
IUUC-Oar-090237 Ovis aries 82.35 1.00e-144 504.00
IUUC-Ptr-090881 Pan troglodytes 82.35 2.00e-144 504.00
IUUC-Pan-092658 Papio anubis 80.87 9.00e-145 505.00
IUUC-Psi-093672 Pelodiscus sinensis 82.35 7.00e-145 505.00
IUUC-Pma-094213 Petromyzon marinus 83.74 2.00e-147 513.00
IUUC-Pno-095038 Phaeosphaeria nodorum 67.86 6.00e-120 422.00
IUUC-Ppa-095637 Physcomitrella patens 91.50 7.00e-154 535.00
IUUC-Pfo-096322 Poecilia formosa 82.35 1.00e-144 504.00
IUUC-Pab-098484 Pongo abelii 82.35 2.00e-144 504.00
IUUC-Pop-099564 Populus trichocarpa 95.79 1.00e-163 567.00
IUUC-Pca-100785 Procavia capensis 75.85 1.00e-117 415.00
IUUC-Ppe-101727 Prunus persica 93.85 9.00e-160 555.00
IUUC-Pva-102569 Pteropus vampyrus 81.36 5.00e-145 506.00
IUUC-Pgr-103351 Puccinia graminis 75.08 3.00e-134 470.00
IUUC-Ptt-103763 Puccinia triticina 70.10 2.00e-120 424.00
IUUC-Pte-104088 Pyrenophora teres 67.86 2.00e-119 421.00
IUUC-Pyt-104597 Pyrenophora triticirepentis 70.94 1.00e-110 392.00
IUUC-Rno-105115 Rattus norvegicus 82.35 2.00e-144 504.00
IUUC-Sce-106353 Saccharomyces cerevisiae 63.64 9.00e-108 382.00
IUUC-Sha-107476 Sarcophilus harrisii 82.35 7.00e-145 505.00
IUUC-Sja-107807 Schizosaccharomyces japonicus 70.78 3.00e-127 447.00
IUUC-Spo-108255 Schizosaccharomyces pombe 70.87 2.00e-118 417.00
IUUC-Ssl-108392 Sclerotinia sclerotiorum 71.53 4.00e-112 397.00
IUUC-Smo-108824 Selaginella moellendorffii 87.82 8.00e-162 561.00
IUUC-Sit-110287 Setaria italica 93.18 2.00e-160 556.00
IUUC-Sly-111656 Solanum lycopersicum 93.20 3.00e-160 556.00
IUUC-Stu-112827 Solanum tuberosum 94.17 2.00e-161 560.00
IUUC-Sar-112979 Sorex araneus 70.71 2.00e-120 424.00
IUUC-Sbi-113841 Sorghum bicolor 93.18 2.00e-160 556.00
IUUC-Sre-114930 Sporisorium reilianum 77.06 3.00e-130 457.00
IUUC-Ssc-116058 Sus scrofa 82.35 1.00e-144 504.00
IUUC-Tgu-116499 Taeniopygia guttata 82.35 1.00e-144 504.00
IUUC-Tru-117576 Takifugu rubripes 82.35 1.00e-144 504.00
IUUC-Tsy-119371 Tarsius syrichta 73.65 6.00e-126 442.00
IUUC-Tni-120868 Tetraodon nigroviridis 82.01 2.00e-142 497.00
IUUC-Tca-121292 Theobroma cacao 95.47 2.00e-163 567.00
IUUC-Tre-122183 Trichoderma reesei 73.31 6.00e-117 412.00
IUUC-Tvi-122566 Trichoderma virens 71.53 7.00e-117 412.00
IUUC-Tae-125156 Triticum aestivum 92.21 3.00e-160 556.00
IUUC-Tur-126034 Triticum urartu 95.37 3.00e-150 523.00
IUUC-Tme-126903 Tuber melanosporum 71.10 5.00e-128 449.00
IUUC-Tbe-127525 Tupaia belangeri 74.72 3.00e-119 420.00
IUUC-Ttr-129072 Tursiops truncatus 82.35 2.00e-144 504.00
IUUC-Uma-129471 Ustilago maydis 77.06 8.00e-131 458.00
IUUC-Vda-129956 Verticillium dahliae 71.89 3.00e-110 390.00
IUUC-Vpa-130490 Vicugna pacos 82.35 2.00e-144 504.00
IUUC-Vvi-131302 Vitis vinifera 95.47 4.00e-163 566.00
IUUC-Xtr-132059 Xenopus tropicalis 82.35 8.00e-145 505.00
IUUC-Xma-133101 Xiphophorus maculatus 82.35 1.00e-144 504.00
IUUC-Yli-134638 Yarrowia lipolytica 70.57 1.00e-119 421.00
IUUC-Zma-135910 Zea mays 93.18 2.00e-160 556.00
Created Date 25-Jun-2017

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