iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aly-006207

Ensembl Protein ID

scaffold_502978.1

UniProt Accession

D7LVZ4; D7LVZ4_ARALL

Genbank Protein ID

EFH52713.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

GL348717

Gene Name

SINAT2; ARALYDRAFT_907274

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
scaffold_502978.1	scaffold_502978.1	scaffold_502978.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	36.10	6.00e-38	154.00	IUUC-Dme-031755
E3 activity/RING/RING	33.94	3.00e-40	163.00	IUUC-Hsa-046357
E3 activity/RING/RING	33.94	2.00e-40	163.00	IUUC-Mmu-064129

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Arabidopsis lyrata

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MAPGGSALKE VMESNSTGMD YEVKTAKVEV NNNNKPTKPG SAGIGKYGIH SNNGVYELLE 60
CPVCTNLMYP PIHQCPNGHT LCSNCKVRVQ NTCPTCRYEL GNIRCLALEK VAESLEVPCR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGAATTAGGG ATTTGGGCTC GCCATGGCTC CTGGAGGCAG TGCTTTGAAA GAAGTCATGG 60
AATCTAATTC AACGGGAATG GATTACGAGG TTAAAACGGC AAAAGTGGAA GTTAATAATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

aly:ARALYDRAFT_907274

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000061	Aegilops tauschii	68.05	2.00e-128	451.00
IUUC-Aml-001186	Ailuropoda melanoleuca	33.94	6.00e-42	163.00
IUUC-Aca-005014	Anolis carolinensis	33.94	9.00e-42	162.00
IUUC-Ath-007049	Arabidopsis thaliana	99.03	0.00e+00	643.00
IUUC-Bta-012887	Bos taurus	33.94	7.00e-42	163.00
IUUC-Bol-016263	Brassica oleracea	95.79	0.00e+00	625.00
IUUC-Bra-016847	Brassica rapa	83.17	2.00e-158	550.00
IUUC-Cja-019796	Callithrix jacchus	33.94	9.00e-42	162.00
IUUC-Cfa-020642	Canis familiaris	33.94	4.00e-42	164.00
IUUC-Cpo-022348	Cavia porcellus	33.94	9.00e-42	162.00
IUUC-Csa-023974	Chlorocebus sabaeus	33.94	9.00e-42	163.00
IUUC-Dno-029764	Dasypus novemcinctus	33.79	4.00e-42	164.00
IUUC-Dme-031755	Drosophila melanogaster	36.10	3.00e-39	154.00
IUUC-Ete-032423	Echinops telfairi	33.94	1.00e-41	162.00
IUUC-Eeu-035314	Erinaceus europaeus	33.10	8.00e-42	163.00
IUUC-Fca-035362	Felis catus	33.94	6.00e-42	163.00
IUUC-Fal-037487	Ficedula albicollis	33.94	7.00e-42	163.00
IUUC-Ggo-045444	Gorilla gorilla	33.94	9.00e-42	163.00
IUUC-Hsa-046357	Homo sapiens	33.94	9.00e-42	163.00
IUUC-Hvu-047574	Hordeum vulgare	68.05	1.00e-128	451.00
IUUC-Itr-048046	Ictidomys tridecemlineatus	33.94	9.00e-42	162.00
IUUC-Lpe-050879	Leersia perrieri	68.81	3.00e-128	450.00
IUUC-Loc-052191	Lepisosteus oculatus	33.94	7.00e-42	163.00
IUUC-Mcc-054640	Macaca mulatta	33.94	9.00e-42	163.00
IUUC-Mtr-057852	Medicago truncatula	77.42	4.00e-147	513.00
IUUC-Mga-059503	Meleagris gallopavo	33.69	9.00e-42	163.00
IUUC-Mmr-060794	Microcebus murinus	33.94	9.00e-42	162.00
IUUC-Mmu-064129	Mus musculus	33.94	6.00e-42	163.00
IUUC-Mpu-066488	Mustela putorius furo	33.94	7.00e-42	163.00
IUUC-Mlu-067207	Myotis lucifugus	34.06	4.00e-42	164.00
IUUC-Nle-069706	Nomascus leucogenys	33.10	8.00e-42	163.00
IUUC-Ocu-074876	Oryctolagus cuniculus	33.94	1.00e-41	162.00
IUUC-Oba-075454	Oryza barthii	68.81	7.00e-128	449.00
IUUC-Ogl-077712	Oryza glaberrima	68.81	7.00e-128	449.00
IUUC-Ogu-078910	Oryza glumaepatula	68.81	8.00e-128	449.00
IUUC-Oin-079749	Oryza indica	68.81	7.00e-128	449.00
IUUC-Ome-081318	Oryza meridionalis	69.13	8.00e-128	449.00
IUUC-Oni-083109	Oryza nivara	68.81	7.00e-128	449.00
IUUC-Opu-084065	Oryza punctata	68.81	2.00e-127	447.00
IUUC-Oru-084785	Oryza rufipogon	68.81	7.00e-128	449.00
IUUC-Osa-085610	Oryza sativa	68.81	7.00e-128	449.00
IUUC-Oga-088399	Otolemur garnettii	33.94	9.00e-42	162.00
IUUC-Oar-089323	Ovis aries	33.94	7.00e-42	163.00
IUUC-Ptr-090692	Pan troglodytes	33.94	1.00e-41	162.00
IUUC-Pan-092012	Papio anubis	33.94	9.00e-42	163.00
IUUC-Psi-093687	Pelodiscus sinensis	33.94	7.00e-42	163.00
IUUC-Ppa-095212	Physcomitrella patens	85.27	4.00e-136	476.00
IUUC-Pab-097555	Pongo abelii	33.94	9.00e-42	163.00
IUUC-Pop-099563	Populus trichocarpa	68.91	3.00e-133	466.00
IUUC-Ppe-101760	Prunus persica	73.79	2.00e-138	484.00
IUUC-Rno-104866	Rattus norvegicus	33.94	6.00e-42	163.00
IUUC-Sha-106547	Sarcophilus harrisii	33.94	8.00e-42	163.00
IUUC-Smo-109412	Selaginella moellendorffii	74.68	7.00e-140	489.00
IUUC-Sly-111117	Solanum lycopersicum	72.82	1.00e-136	478.00
IUUC-Stu-112714	Solanum tuberosum	70.97	1.00e-134	471.00
IUUC-Tae-123647	Triticum aestivum	68.05	2.00e-128	451.00
IUUC-Ttr-129166	Tursiops truncatus	35.42	2.00e-39	155.00
IUUC-Vvi-131233	Vitis vinifera	81.82	8.00e-153	531.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence