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Tag Content
UUCD2 ID IUUC-Ggo-044903
UUCD1 version UUC-GoG-00061
Ensembl Protein ID ENSGGOP00000007292.2
UniProt Accession G3QWW8; G3QWW8_GORGO
Protein Name Uncharacterized protein
Gene Name CUL3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSGGOG00000007447.2 ENSGGOT00000007485.2 ENSGGOP00000007292.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 1.40e-228 761.0 15 644
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 2    lreavkkilrqesvkkeyeelytavynlclskvgaklYkklkevleefi.kqvkkkveesedeqlLktynreWekfreqlkvlrkifay 89
           l++a+++i+r++++  ++eely+++y+++l+k+g+klY+ l+ev++e++ ++v+++v +s ++++L+t+n++W++++++++++r+i++y
   Q: 15   LKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLiNKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMY 103
           799*********************************************99*************************************** PP
   S: 90   ldrtyvkkskkvsevrkLaldlwrkeived..ikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfleat 176
           +dr+yv++ ++v++v++L+l ++r+++v++  i+++l ++ll++i++eRkge+vdr  +++++++l+ L+l+ +++y+e+FEa+fle++
   Q: 104  MDRVYVQQ-NNVENVYNLGLIIFRDQVVRYgcIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMS 191
           ********.******************************************************************************** PP
   S: 177  qefyk.aesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesll....aelvallrdkktedlsrmyk 260
           +ef++ +es++fl+en+ + Y+kkvear+nee er++++l++ste+++++vve+eli+kh+++++    ++lv++l++ ktedl++myk
   Q: 192  AEFFQqMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVemenSGLVHMLKNGKTEDLGCMYK 280
           **997269*********************************************************99999******************* PP
   S: 261  LlsrvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaaksp 349
           L+srv+ngl++++++++s+++eqgka++++e + k+p++y++ ll+lk+++++++ e+Fnnd+ F ++++ +fe+f+n n     ++sp
   Q: 281  LFSRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLLESFNNDRLFKQTIAGDFEYFLNLN-----SRSP 364
           ********************************************************************************.....**** PP
   S: 350  EllAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMf 438
           E+l+ +iD++L+k++kglte+e+e++ldk++++f++++ekdvFe+yYk+hLa+RLl++ks+s+++E+++i+kLk+ecg++ftskLe+Mf
   Q: 365  EYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMF 453
           ***************************************************************************************** PP
   S: 439  qdlkvSedlnrqFkeekentees.esvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkael 526
           +d+++S++++++F+++ ++t  s  +v+l+v+vL++g+Wpt+s+t+k+++P+  ++++e+f++fYl khsgR+L++qh++g+a+l+a++
   Q: 454  RDMSISNTTMDEFRQHLQATGVSlGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATF 542
           *********************99889*************************************************************** PP
   S: 527  ......................kkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvssk..kqvlkkepeske 591
                                 +++k++lqVstfQm++L++fnn+ek+++ee++++t++pe+eL r+lqsL+++k  ++vl+kep+ske
   Q: 543  ygpvkkedgsevgvggaqvtgsNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKptQRVLTKEPKSKE 631
           **********999999998888888**************************************************************** PP
   S: 592  ieeedlfsvNqef 604
           ie++++f+vN++f
   Q: 632  IENGHIFTVNDQF 644
           ***********99 PP
   
Organism Gorilla gorilla
Protein Sequence
(Fasta)
MTMDEKYVNS IWDLLKNAIQ EIQRKNNSGL SFEELYRNAY TMVLHKHGEK LYTGLREVVT 60
EHLINKVRED VLNSLNNNFL QTLNQAWNDH QTAMVMIRDI LMYMDRVYVQ QNNVENVYNL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ggo-044903|E3,Cullin|Gorilla gorilla
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GACACCAAGA TGCGGATCCG GGCCTTTCCG GTGAGTCTCT CCTCGGCGTC CGGGACCCCG 60
GGGCTGGGGG CCGGGCCGAG AGCCGCACGC GAGGCCCGGG CTGAAGTCCC CCAACAGGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ggo-044903|E3,Cullin|Gorilla gorilla
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8
Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0070062--C:extracellular exosome
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005827--C:polar microtubule
GO:0004842--F:ubiquitin-protein transferase activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0016477--P:cell migration
GO:0048208--P:COPII vesicle coating
GO:0040016--P:embryonic cleavage
GO:0044346--P:fibroblast apoptotic process
GO:0007369--P:gastrulation
GO:0007229--P:integrin-mediated signaling pathway
GO:0072576--P:liver morphogenesis
GO:0007080--P:mitotic metaphase plate congression
GO:0035024--P:negative regulation of Rho protein signal transduction
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032467--P:positive regulation of cytokinesis
GO:0045842--P:positive regulation of mitotic metaphase/anaphase transition
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0017145--P:stem cell division
GO:0043149--P:stress fiber assembly
GO:0001831--P:trophectodermal cellular morphogenesis
GO:0071630--P:ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome
GO:0016055--P:Wnt signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000335 Aegilops tauschii 47.01 0.00e+00 680.00
IUUC-Aml-002278 Ailuropoda melanoleuca 99.07 0.00e+00 1509.00
IUUC-Atr-002616 Amborella trichopoda 53.15 0.00e+00 767.00
IUUC-Apl-004172 Anas platyrhynchos 99.46 0.00e+00 1511.00
IUUC-Aca-004309 Anolis carolinensis 99.46 0.00e+00 1512.00
IUUC-Aly-005566 Arabidopsis lyrata 52.27 0.00e+00 764.00
IUUC-Ath-007587 Arabidopsis thaliana 52.67 0.00e+00 768.00
IUUC-Ago-007795 Ashbya gossypii 25.17 2.00e-47 184.00
IUUC-Acl-008317 Aspergillus clavatus 36.83 7.00e-143 501.00
IUUC-Afl-008727 Aspergillus flavus 36.49 7.00e-143 501.00
IUUC-Afu-008879 Aspergillus fumigatus 37.91 6.00e-131 461.00
IUUC-Ani-009393 Aspergillus nidulans 35.94 2.00e-133 469.00
IUUC-Ang-009626 Aspergillus niger 36.40 3.00e-139 489.00
IUUC-Aor-010207 Aspergillus oryzae 36.49 1.00e-142 500.00
IUUC-Ate-010305 Aspergillus terreus 37.12 6.00e-139 488.00
IUUC-Ame-011805 Astyanax mexicanus 97.05 0.00e+00 1477.00
IUUC-Bgr-012098 Blumeria graminis 35.98 9.00e-120 424.00
IUUC-Bta-013445 Bos taurus 99.60 0.00e+00 1514.00
IUUC-Bci-013612 Botrytis cinerea 36.56 4.00e-137 482.00
IUUC-Bdi-014269 Brachypodium distachyon 53.35 0.00e+00 741.00
IUUC-Bol-015350 Brassica oleracea 52.81 0.00e+00 767.00
IUUC-Bra-016763 Brassica rapa 52.94 0.00e+00 769.00
IUUC-Cel-018641 Caenorhabditis elegans 48.62 0.00e+00 717.00
IUUC-Cja-019175 Callithrix jacchus 99.73 0.00e+00 1516.00
IUUC-Cfa-020905 Canis familiaris 99.60 0.00e+00 1513.00
IUUC-Cpo-021293 Cavia porcellus 99.46 0.00e+00 1511.00
IUUC-Cre-022776 Chlamydomonas reinhardtii 48.54 0.00e+00 692.00
IUUC-Csa-023800 Chlorocebus sabaeus 99.87 0.00e+00 1518.00
IUUC-Cho-024839 Choloepus hoffmanni 98.53 0.00e+00 1346.00
IUUC-Cin-025201 Ciona intestinalis 71.49 0.00e+00 996.00
IUUC-Csv-026107 Ciona savignyi 71.30 0.00e+00 1085.00
IUUC-Cgl-026630 Colletotrichum gloeosporioides 35.51 2.00e-123 436.00
IUUC-Cne-027048 Cryptococcus neoformans 34.76 7.00e-116 411.00
IUUC-Cme-027254 Cyanidioschyzon merolae 31.19 8.00e-87 315.00
IUUC-Dre-028488 Danio rerio 97.46 0.00e+00 1485.00
IUUC-Dno-029784 Dasypus novemcinctus 99.60 0.00e+00 1514.00
IUUC-Dor-030682 Dipodomys ordii 92.24 0.00e+00 1363.00
IUUC-Dse-031326 Dothistroma septosporum 35.70 3.00e-127 449.00
IUUC-Dme-032112 Drosophila melanogaster 69.40 0.00e+00 1071.00
IUUC-Ete-032347 Echinops telfairi 82.73 0.00e+00 1190.00
IUUC-Eca-033560 Equus caballus 99.46 0.00e+00 1513.00
IUUC-Eeu-034502 Erinaceus europaeus 97.50 0.00e+00 1336.00
IUUC-Fca-035544 Felis catus 99.60 0.00e+00 1513.00
IUUC-Fal-036751 Ficedula albicollis 99.60 0.00e+00 1513.00
IUUC-Fox-037857 Fusarium oxysporum 36.87 5.00e-136 478.00
IUUC-Fso-038163 Fusarium solani 36.71 1.00e-139 490.00
IUUC-Gmo-038830 Gadus morhua 97.59 0.00e+00 1493.00
IUUC-Ggr-039999 Gaeumannomyces graminis 33.73 2.00e-125 442.00
IUUC-Gga-040329 Gallus gallus 99.46 0.00e+00 1512.00
IUUC-Gac-041510 Gasterosteus aculeatus 96.81 0.00e+00 1479.00
IUUC-Gma-043659 Glycine max 53.01 0.00e+00 740.00
IUUC-Hsa-046000 Homo sapiens 99.87 0.00e+00 1518.00
IUUC-Hvu-047831 Hordeum vulgare 52.53 0.00e+00 697.00
IUUC-Itr-049067 Ictidomys tridecemlineatus 99.78 0.00e+00 939.00
IUUC-Kpa-049372 Komagataella pastoris 34.90 3.00e-114 405.00
IUUC-Lch-050458 Latimeria chalumnae 99.33 0.00e+00 1512.00
IUUC-Lpe-051396 Leersia perrieri 52.41 0.00e+00 749.00
IUUC-Loc-052186 Lepisosteus oculatus 98.80 0.00e+00 1507.00
IUUC-Lma-053030 Leptosphaeria maculans 38.50 2.00e-142 499.00
IUUC-Laf-053684 Loxodonta africana 99.60 0.00e+00 1513.00
IUUC-Mcc-055770 Macaca mulatta 99.87 0.00e+00 1518.00
IUUC-Meu-056852 Macropus eugenii 100.00 0.00e+00 763.00
IUUC-Mor-057273 Magnaporthe oryzae 34.59 8.00e-131 461.00
IUUC-Mpo-057403 Magnaporthe poae 33.85 2.00e-127 450.00
IUUC-Mtr-058317 Medicago truncatula 52.27 0.00e+00 747.00
IUUC-Mla-059055 Melampsora laricipopulina 37.61 6.00e-132 464.00
IUUC-Mga-060076 Meleagris gallopavo 97.86 0.00e+00 1480.00
IUUC-Mvi-060470 Microbotryum violaceum 33.60 3.00e-134 473.00
IUUC-Mmr-060976 Microcebus murinus 99.60 0.00e+00 1514.00
IUUC-Mdo-062741 Monodelphis domestica 99.60 0.00e+00 1514.00
IUUC-Mmu-063905 Mus musculus 99.33 0.00e+00 1508.00
IUUC-Mac-064718 Musa acuminata 51.41 0.00e+00 723.00
IUUC-Mpu-066356 Mustela putorius furo 99.60 0.00e+00 1513.00
IUUC-Mlu-067768 Myotis lucifugus 99.07 0.00e+00 1507.00
IUUC-Nfi-068285 Neosartorya fischeri 37.15 1.00e-144 507.00
IUUC-Ncr-068883 Neurospora crassa 36.49 7.00e-137 481.00
IUUC-Nle-069638 Nomascus leucogenys 99.87 0.00e+00 1518.00
IUUC-Opr-070333 Ochotona princeps 90.48 0.00e+00 1261.00
IUUC-Ont-071601 Oreochromis niloticus 97.99 0.00e+00 1529.00
IUUC-Oan-073281 Ornithorhynchus anatinus 99.36 0.00e+00 1294.00
IUUC-Ocu-074504 Oryctolagus cuniculus 99.60 0.00e+00 1513.00
IUUC-Oba-075332 Oryza barthii 52.84 0.00e+00 740.00
IUUC-Obr-076435 Oryza brachyantha 52.90 0.00e+00 708.00
IUUC-Ogl-077655 Oryza glaberrima 52.82 0.00e+00 750.00
IUUC-Ogu-078458 Oryza glumaepatula 52.84 0.00e+00 741.00
IUUC-Oin-079567 Oryza indica 52.68 0.00e+00 748.00
IUUC-Olo-080930 Oryza longistaminata 52.82 0.00e+00 751.00
IUUC-Ome-081353 Oryza meridionalis 52.82 0.00e+00 749.00
IUUC-Oni-082378 Oryza nivara 52.82 0.00e+00 750.00
IUUC-Opu-084055 Oryza punctata 52.82 0.00e+00 751.00
IUUC-Oru-084202 Oryza rufipogon 52.84 0.00e+00 741.00
IUUC-Osa-085290 Oryza sativa 52.82 0.00e+00 750.00
IUUC-Ola-087562 Oryzias latipes 97.72 0.00e+00 1493.00
IUUC-Olu-087866 Ostreococcus lucimarinus 37.74 5.00e-139 488.00
IUUC-Oga-088833 Otolemur garnettii 99.60 0.00e+00 1513.00
IUUC-Oar-089958 Ovis aries 99.60 0.00e+00 1513.00
IUUC-Ptr-091013 Pan troglodytes 99.87 0.00e+00 1518.00
IUUC-Pan-091796 Papio anubis 99.20 0.00e+00 1508.00
IUUC-Psi-093564 Pelodiscus sinensis 97.86 0.00e+00 1477.00
IUUC-Pno-094939 Phaeosphaeria nodorum 38.18 9.00e-138 484.00
IUUC-Ppa-095920 Physcomitrella patens 52.61 0.00e+00 759.00
IUUC-Pfo-097498 Poecilia formosa 93.47 0.00e+00 1474.00
IUUC-Pab-098164 Pongo abelii 99.87 0.00e+00 1518.00
IUUC-Pop-099497 Populus trichocarpa 53.88 0.00e+00 783.00
IUUC-Pca-100702 Procavia capensis 91.30 0.00e+00 1340.00
IUUC-Ppe-101271 Prunus persica 52.94 0.00e+00 740.00
IUUC-Pva-103129 Pteropus vampyrus 99.46 0.00e+00 1513.00
IUUC-Pgr-103684 Puccinia graminis 36.39 6.00e-109 388.00
IUUC-Ptt-103961 Puccinia triticina 36.57 3.00e-108 386.00
IUUC-Pte-104325 Pyrenophora teres 38.01 4.00e-134 472.00
IUUC-Pyt-104746 Pyrenophora triticirepentis 37.05 4.00e-132 465.00
IUUC-Rno-105935 Rattus norvegicus 99.46 0.00e+00 1510.00
IUUC-Sce-106354 Saccharomyces cerevisiae 26.75 2.00e-53 204.00
IUUC-Sha-106569 Sarcophilus harrisii 98.98 0.00e+00 1377.00
IUUC-Sja-107676 Schizosaccharomyces japonicus 38.70 4.00e-153 535.00
IUUC-Spo-108135 Schizosaccharomyces pombe 37.87 5.00e-136 478.00
IUUC-Smo-109555 Selaginella moellendorffii 53.28 0.00e+00 781.00
IUUC-Sit-110763 Setaria italica 53.75 0.00e+00 758.00
IUUC-Sly-111090 Solanum lycopersicum 52.41 0.00e+00 759.00
IUUC-Stu-112351 Solanum tuberosum 52.54 0.00e+00 762.00
IUUC-Sar-113144 Sorex araneus 99.45 0.00e+00 1110.00
IUUC-Sbi-114690 Sorghum bicolor 52.95 0.00e+00 757.00
IUUC-Sre-115005 Sporisorium reilianum 37.85 5.00e-133 468.00
IUUC-Ssc-116053 Sus scrofa 99.45 0.00e+00 1138.00
IUUC-Tgu-116523 Taeniopygia guttata 99.60 0.00e+00 1513.00
IUUC-Tru-118189 Takifugu rubripes 93.98 0.00e+00 1403.00
IUUC-Tsy-118962 Tarsius syrichta 93.41 0.00e+00 1381.00
IUUC-Tni-120614 Tetraodon nigroviridis 57.41 0.00e+00 867.00
IUUC-Tca-121282 Theobroma cacao 53.33 0.00e+00 764.00
IUUC-Tre-122201 Trichoderma reesei 35.71 3.00e-132 466.00
IUUC-Tvi-122321 Trichoderma virens 36.32 5.00e-133 468.00
IUUC-Tae-124292 Triticum aestivum 52.68 0.00e+00 736.00
IUUC-Tur-126800 Triticum urartu 52.55 0.00e+00 735.00
IUUC-Tme-127053 Tuber melanosporum 40.42 2.00e-155 543.00
IUUC-Tbe-127427 Tupaia belangeri 84.80 0.00e+00 1155.00
IUUC-Ttr-128662 Tursiops truncatus 97.86 0.00e+00 1472.00
IUUC-Uma-129597 Ustilago maydis 38.21 7.00e-132 464.00
IUUC-Vda-129726 Verticillium dahliae 35.22 2.00e-132 466.00
IUUC-Vpa-130809 Vicugna pacos 99.20 0.00e+00 736.00
IUUC-Vvi-131194 Vitis vinifera 52.93 0.00e+00 758.00
IUUC-Xtr-131887 Xenopus tropicalis 98.53 0.00e+00 1498.00
IUUC-Xma-133517 Xiphophorus maculatus 97.86 0.00e+00 1494.00
IUUC-Yli-134576 Yarrowia lipolytica 33.33 4.00e-111 395.00
IUUC-Zma-135030 Zea mays 53.35 0.00e+00 763.00
Created Date 25-Jun-2017

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