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Tag Content
UUCD2 ID IUUC-Oan-073281
UUCD1 version UUC-OrA-00651
Ensembl Protein ID ENSOANP00000019579.2
UniProt Accession F7F881; F7F881_ORNAN
Protein Name Uncharacterized protein
Gene Name CUL3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOANG00000012372.3 ENSOANT00000019582.3 ENSOANP00000019579.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 4.70e-198 660.0 1 539
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 91   drtyvkkskkvsevrkLaldlwrkeived..ikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfleatq 177
           dr+yv++ ++v++v++L+l ++r+++v++  i+++l ++ll++i++eRkge+vdr  +++++++l+ L+l+ +++y+e+FEa+fle+++
   Q: 1    DRVYVQQ-NNVENVYNLGLIIFRDQVVRYgcIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSA 88
           799****.********************************************************************************* PP
   S: 178  efykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesll....aelvallrdkktedlsrmykLl 262
           ef+++es++fl+en+ + Y+kkvear+nee er++++l++ste+++++vve+eli+kh+++++    ++lv++l++ ktedl++mykL+
   Q: 89   EFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVemenSGLVHMLKNGKTEDLACMYKLF 177
           ***************************************************************99999********************* PP
   S: 263  srvlngleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaakspEl 351
           srv+ngl++++++++s+++eqgka++++e + k+p++y++ ll+lk++++++++e+Fnnd+ F ++++ +fe+f+n n     ++spE+
   Q: 178  SRVPNGLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLN-----SRSPEY 261
           ******************************************************************************.....****** PP
   S: 352  lAryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfqd 440
           l+ +iD++L+k++kglte+e+e++ldk++++f++++ekdvFe+yYk+hLa+RLl++ks+s+++E+++i+kLk+ecg++ftskLe+Mf+d
   Q: 262  LSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRD 350
           ***************************************************************************************** PP
   S: 441  lkvSedlnrqFkeekentees.esvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkael.. 526
           +++S++++++F+++ ++t  s  +v+l+v+vL++g+Wpt+s+t+k+++P+  ++++e+f++fYl khsgR+L++qh++g+a+l+a++  
   Q: 351  MSISNTTMDEFRQHLQSTGVSlGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFyg 439
           *******************99889***************************************************************** PP
   S: 527  ....................kkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvssk..kqvlkkepeskeie 593
                               +++k++lqVstfQm++L++fnn+ek+++ee++++t++pe+eL r+lqsL+++k  ++vl+kep+skeie
   Q: 440  pvkkedgsevgvggaqvtgsNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKptQRVLTKEPKSKEIE 528
           ********999999998888888****************************************************************** PP
   S: 594  eedlfsvNqef 604
           ++++f+vN++f
   Q: 529  NGHIFTVNDQF 539
           *********99 PP
   
Organism Ornithorhynchus anatinus
Protein Sequence
(Fasta)
DRVYVQQNNV ENVYNLGLII FRDQVVRYGC IRDHLRQTLL DMIARERKGE VVDRGAIRNA 60
CQMLMILGLE GRSVYEEDFE APFLEMSAEF FQMESQKFLA ENSASVYIKK VEARINEEIE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oan-073281|E3,Cullin|Ornithorhynchus anatinus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAAAATATAA GGATGCATAT TTATGTGTAT TTTCTTTTTC GATTGTAGGA CCGAGTATAT 60
GTACAACAAA ATAACGTGGA GAATGTCTAC AATTTGGGAT TAATAATTTT TCGAGATCAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oan-073281|E3,Cullin|Ornithorhynchus anatinus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8
Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0070062--C:extracellular exosome
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005827--C:polar microtubule
GO:0031625--F:ubiquitin protein ligase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0016477--P:cell migration
GO:0000902--P:cell morphogenesis
GO:0048208--P:COPII vesicle coating
GO:0040016--P:embryonic cleavage
GO:0044346--P:fibroblast apoptotic process
GO:0007369--P:gastrulation
GO:0007229--P:integrin-mediated signaling pathway
GO:0072576--P:liver morphogenesis
GO:0007080--P:mitotic metaphase plate congression
GO:0035024--P:negative regulation of Rho protein signal transduction
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032467--P:positive regulation of cytokinesis
GO:0045842--P:positive regulation of mitotic metaphase/anaphase transition
GO:0006513--P:protein monoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0017145--P:stem cell division
GO:0043149--P:stress fiber assembly
GO:0071630--P:ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome
GO:0016055--P:Wnt signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000335 Aegilops tauschii 50.54 2.00e-179 621.00
IUUC-Aml-002278 Ailuropoda melanoleuca 99.21 0.00e+00 1298.00
IUUC-Atr-002616 Amborella trichopoda 52.80 0.00e+00 663.00
IUUC-Apl-004172 Anas platyrhynchos 99.84 0.00e+00 1303.00
IUUC-Aca-004309 Anolis carolinensis 99.84 0.00e+00 1303.00
IUUC-Aly-005566 Arabidopsis lyrata 52.26 0.00e+00 658.00
IUUC-Ath-007587 Arabidopsis thaliana 52.72 0.00e+00 663.00
IUUC-Acl-008317 Aspergillus clavatus 36.86 5.00e-122 431.00
IUUC-Afl-008727 Aspergillus flavus 36.87 1.00e-123 436.00
IUUC-Afu-008879 Aspergillus fumigatus 37.09 7.00e-123 434.00
IUUC-Ani-009393 Aspergillus nidulans 36.39 1.00e-116 413.00
IUUC-Ang-009626 Aspergillus niger 37.34 4.00e-123 434.00
IUUC-Aor-010207 Aspergillus oryzae 36.87 3.00e-123 435.00
IUUC-Ate-010305 Aspergillus terreus 37.63 7.00e-120 424.00
IUUC-Ame-011805 Astyanax mexicanus 97.61 0.00e+00 1274.00
IUUC-Bgr-012098 Blumeria graminis 35.56 3.00e-100 358.00
IUUC-Bta-013445 Bos taurus 99.84 0.00e+00 1302.00
IUUC-Bci-013612 Botrytis cinerea 36.67 5.00e-118 417.00
IUUC-Bdi-014269 Brachypodium distachyon 53.34 0.00e+00 639.00
IUUC-Bol-015350 Brassica oleracea 52.72 0.00e+00 661.00
IUUC-Bra-016763 Brassica rapa 52.88 0.00e+00 664.00
IUUC-Cel-018641 Caenorhabditis elegans 45.81 5.00e-165 574.00
IUUC-Cja-019175 Callithrix jacchus 99.68 0.00e+00 1300.00
IUUC-Cfa-020905 Canis familiaris 99.84 0.00e+00 1304.00
IUUC-Cpo-021293 Cavia porcellus 99.68 0.00e+00 1301.00
IUUC-Cre-022776 Chlamydomonas reinhardtii 48.53 3.00e-170 591.00
IUUC-Csa-023800 Chlorocebus sabaeus 99.52 0.00e+00 1298.00
IUUC-Cho-024839 Choloepus hoffmanni 98.72 0.00e+00 1272.00
IUUC-Cin-025201 Ciona intestinalis 69.11 0.00e+00 816.00
IUUC-Csv-026107 Ciona savignyi 69.41 0.00e+00 911.00
IUUC-Cgl-026630 Colletotrichum gloeosporioides 35.83 9.00e-106 377.00
IUUC-Cne-027048 Cryptococcus neoformans 35.26 8.00e-98 350.00
IUUC-Cme-027254 Cyanidioschyzon merolae 30.21 3.00e-70 259.00
IUUC-Dre-028488 Danio rerio 97.77 0.00e+00 1278.00
IUUC-Dno-029784 Dasypus novemcinctus 99.84 0.00e+00 1303.00
IUUC-Dor-030682 Dipodomys ordii 91.07 0.00e+00 1149.00
IUUC-Dse-031326 Dothistroma septosporum 35.41 1.00e-105 377.00
IUUC-Dme-032112 Drosophila melanogaster 68.36 0.00e+00 908.00
IUUC-Ete-032347 Echinops telfairi 85.49 0.00e+00 1071.00
IUUC-Eca-033560 Equus caballus 99.68 0.00e+00 1303.00
IUUC-Eeu-034502 Erinaceus europaeus 97.61 0.00e+00 1263.00
IUUC-Fca-035544 Felis catus 99.84 0.00e+00 1303.00
IUUC-Fal-036751 Ficedula albicollis 99.84 0.00e+00 1303.00
IUUC-Fox-037857 Fusarium oxysporum 36.57 2.00e-115 409.00
IUUC-Fso-038163 Fusarium solani 36.51 3.00e-119 422.00
IUUC-Gmo-039270 Gadus morhua 96.99 0.00e+00 1279.00
IUUC-Ggr-039999 Gaeumannomyces graminis 34.34 4.00e-108 385.00
IUUC-Gga-040329 Gallus gallus 100.00 0.00e+00 1303.00
IUUC-Gac-041510 Gasterosteus aculeatus 96.99 0.00e+00 1278.00
IUUC-Gma-043182 Glycine max 52.46 0.00e+00 630.00
IUUC-Ggo-044903 Gorilla gorilla 99.36 0.00e+00 1294.00
IUUC-Hsa-046000 Homo sapiens 99.52 0.00e+00 1298.00
IUUC-Hvu-047831 Hordeum vulgare 52.72 0.00e+00 637.00
IUUC-Itr-049067 Ictidomys tridecemlineatus 99.78 0.00e+00 939.00
IUUC-Kpa-049372 Komagataella pastoris 34.28 6.00e-94 338.00
IUUC-Lch-050458 Latimeria chalumnae 99.36 0.00e+00 1298.00
IUUC-Lpe-051396 Leersia perrieri 52.88 0.00e+00 655.00
IUUC-Loc-052186 Lepisosteus oculatus 99.36 0.00e+00 1301.00
IUUC-Lma-053030 Leptosphaeria maculans 39.17 7.00e-123 434.00
IUUC-Laf-053684 Loxodonta africana 99.84 0.00e+00 1303.00
IUUC-Mcc-055770 Macaca mulatta 99.52 0.00e+00 1298.00
IUUC-Meu-056852 Macropus eugenii 99.73 0.00e+00 761.00
IUUC-Mor-057273 Magnaporthe oryzae 34.99 2.00e-112 399.00
IUUC-Mpo-057403 Magnaporthe poae 34.34 4.00e-110 391.00
IUUC-Mtr-058317 Medicago truncatula 51.87 0.00e+00 637.00
IUUC-Mla-059055 Melampsora laricipopulina 36.76 2.00e-110 392.00
IUUC-Mga-060076 Meleagris gallopavo 98.09 0.00e+00 1273.00
IUUC-Mvi-060470 Microbotryum violaceum 33.38 2.00e-115 409.00
IUUC-Mmr-060976 Microcebus murinus 99.84 0.00e+00 1302.00
IUUC-Mdo-062741 Monodelphis domestica 99.84 0.00e+00 1302.00
IUUC-Mmu-063905 Mus musculus 99.52 0.00e+00 1298.00
IUUC-Mac-064718 Musa acuminata 51.32 4.00e-180 624.00
IUUC-Mpu-066356 Mustela putorius furo 99.84 0.00e+00 1303.00
IUUC-Mlu-067768 Myotis lucifugus 99.21 0.00e+00 1297.00
IUUC-Nfi-068285 Neosartorya fischeri 37.38 9.00e-124 437.00
IUUC-Ncr-068883 Neurospora crassa 37.71 1.00e-120 427.00
IUUC-Nle-069638 Nomascus leucogenys 99.52 0.00e+00 1298.00
IUUC-Opr-070333 Ochotona princeps 89.21 0.00e+00 1065.00
IUUC-Ont-071601 Oreochromis niloticus 98.29 0.00e+00 1322.00
IUUC-Ocu-074504 Oryctolagus cuniculus 99.84 0.00e+00 1303.00
IUUC-Oba-075332 Oryza barthii 53.22 0.00e+00 645.00
IUUC-Obr-076435 Oryza brachyantha 53.50 0.00e+00 657.00
IUUC-Ogl-077655 Oryza glaberrima 53.19 0.00e+00 655.00
IUUC-Ogu-078458 Oryza glumaepatula 53.22 0.00e+00 646.00
IUUC-Oin-079567 Oryza indica 53.19 0.00e+00 655.00
IUUC-Olo-080930 Oryza longistaminata 53.19 0.00e+00 655.00
IUUC-Ome-081353 Oryza meridionalis 53.19 0.00e+00 654.00
IUUC-Oni-082378 Oryza nivara 53.19 0.00e+00 655.00
IUUC-Opu-084055 Oryza punctata 53.19 0.00e+00 656.00
IUUC-Oru-084202 Oryza rufipogon 53.22 0.00e+00 645.00
IUUC-Osa-085290 Oryza sativa 53.19 0.00e+00 655.00
IUUC-Ola-087562 Oryzias latipes 97.93 0.00e+00 1284.00
IUUC-Olu-087866 Ostreococcus lucimarinus 38.45 6.00e-125 441.00
IUUC-Oga-088833 Otolemur garnettii 99.84 0.00e+00 1303.00
IUUC-Oar-089958 Ovis aries 99.84 0.00e+00 1303.00
IUUC-Ptr-091013 Pan troglodytes 99.52 0.00e+00 1298.00
IUUC-Pan-091796 Papio anubis 98.73 0.00e+00 1288.00
IUUC-Psi-093564 Pelodiscus sinensis 97.77 0.00e+00 1267.00
IUUC-Pno-094939 Phaeosphaeria nodorum 39.10 7.00e-123 434.00
IUUC-Ppa-095920 Physcomitrella patens 52.49 0.00e+00 658.00
IUUC-Pfo-097498 Poecilia formosa 92.89 0.00e+00 1268.00
IUUC-Pab-098164 Pongo abelii 99.52 0.00e+00 1298.00
IUUC-Pop-099497 Populus trichocarpa 53.50 0.00e+00 671.00
IUUC-Pca-100702 Procavia capensis 89.79 0.00e+00 1130.00
IUUC-Ppe-101971 Prunus persica 52.33 0.00e+00 629.00
IUUC-Pva-103129 Pteropus vampyrus 99.68 0.00e+00 1303.00
IUUC-Pgr-103684 Puccinia graminis 36.23 2.00e-102 366.00
IUUC-Ptt-103961 Puccinia triticina 36.41 8.00e-102 364.00
IUUC-Pte-104325 Pyrenophora teres 38.18 1.00e-113 403.00
IUUC-Pyt-104746 Pyrenophora triticirepentis 37.04 1.00e-111 397.00
IUUC-Rno-105935 Rattus norvegicus 99.68 0.00e+00 1301.00
IUUC-Sha-106569 Sarcophilus harrisii 99.68 0.00e+00 1300.00
IUUC-Sja-107676 Schizosaccharomyces japonicus 38.65 2.00e-129 456.00
IUUC-Spo-108135 Schizosaccharomyces pombe 38.53 2.00e-117 416.00
IUUC-Smo-109555 Selaginella moellendorffii 53.27 0.00e+00 679.00
IUUC-Sit-110763 Setaria italica 53.97 0.00e+00 654.00
IUUC-Sly-111090 Solanum lycopersicum 52.26 0.00e+00 655.00
IUUC-Stu-112351 Solanum tuberosum 52.41 0.00e+00 655.00
IUUC-Sar-113144 Sorex araneus 99.77 0.00e+00 900.00
IUUC-Sbi-114690 Sorghum bicolor 53.03 0.00e+00 657.00
IUUC-Sre-115005 Sporisorium reilianum 38.61 2.00e-130 459.00
IUUC-Ssc-116053 Sus scrofa 99.64 0.00e+00 1140.00
IUUC-Tgu-116523 Taeniopygia guttata 99.84 0.00e+00 1303.00
IUUC-Tru-118189 Takifugu rubripes 93.14 0.00e+00 1192.00
IUUC-Tsy-118962 Tarsius syrichta 92.31 0.00e+00 1170.00
IUUC-Tni-120614 Tetraodon nigroviridis 60.40 0.00e+00 784.00
IUUC-Tca-121282 Theobroma cacao 52.80 0.00e+00 655.00
IUUC-Tre-122201 Trichoderma reesei 35.55 3.00e-113 402.00
IUUC-Tvi-122321 Trichoderma virens 36.31 6.00e-114 404.00
IUUC-Tae-124292 Triticum aestivum 52.72 0.00e+00 637.00
IUUC-Tur-126800 Triticum urartu 52.57 0.00e+00 635.00
IUUC-Tme-127053 Tuber melanosporum 39.82 3.00e-131 461.00
IUUC-Tbe-127427 Tupaia belangeri 88.53 0.00e+00 1041.00
IUUC-Ttr-128662 Tursiops truncatus 97.61 0.00e+00 1263.00
IUUC-Uma-129597 Ustilago maydis 38.97 1.00e-129 457.00
IUUC-Vda-129726 Verticillium dahliae 35.54 8.00e-114 404.00
IUUC-Vpa-130809 Vicugna pacos 99.03 0.00e+00 646.00
IUUC-Vvi-131194 Vitis vinifera 52.72 0.00e+00 656.00
IUUC-Xtr-131887 Xenopus tropicalis 98.73 0.00e+00 1288.00
IUUC-Xma-133517 Xiphophorus maculatus 98.09 0.00e+00 1288.00
IUUC-Yli-134576 Yarrowia lipolytica 33.09 1.00e-90 327.00
IUUC-Zma-135030 Zea mays 53.50 0.00e+00 663.00
Created Date 25-Jun-2017

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