iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-000936

Ensembl Protein ID

EMT26052

UniProt Accession

M8CFV2; M8CFV2_AEGTA

Genbank Protein ID

EMT26052.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

KD514045

Gene Name

F775_11663

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_11663	EMT26052	EMT26052

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	3.70e-73	247.6	2	321

Active Site

Position(s)	Description	Evidence
82	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
157	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAllsv 107
           +w+++esdPg+ft+l+++  vk++ qveelysLd ++l+++ +pv+gl++lFk+ +  + +r          vv  d   ++ffa qvi N+Cat+A+ls 
   Q: 2    SWCTIESDPGVFTELIQEMQVKGV-QVEELYSLDVDSLSQL-QPVYGLIFLFKWMPGGNDERP---------VV-SDPNPNLFFARQVITNACATQAILSI 90
           7***********************.****************.9*************9999993.........33.56678********************* PP
   S: 108  llncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglkpfPldlgkk.. 206
           l n  +   d+G++ls+lke+t a+ p++k+la++n++ ++++hns+ar+e++ ++e++++++   ++e++hf+sy++ +g lyeldglk+ P+ lg+   
   Q: 91   LMNRPEI--DIGPELSNLKEFTGAFAPDMKGLAINNSDSIRAAHNSFARPEPFVSDEQKAATK---DDEVYHFISYIPFEGVLYELDGLKEGPISLGQYpg 186
           ***9998..***********************************************9997665...9******************************9976 PP
   S: 207  .keteelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkid..................keLlkLlkdieseeekieaqlddekekrk 288
             e+  + + ++ v+   eri+ +++ eirfnl+ai ++r+ ++t+ l+ l+                    + L + l ++    e   ++++ e+ek +
   Q: 187  gPEDLGWLQMVQPVI--QERIERYSQSEIRFNLMAIIKNRKDVYTAELKELEKKreqilqelsseataaaekEPLNSALAEVAVAGEAVGEKIAMEEEKFR 285
           678889*********..******************************988877799***************76699************************* PP
   S: 289  kfkiddirRtenydeficifikdlaregilrklvee 324
           k+k ++ rR++ny  f++ ++k la++++l  lve+
   Q: 286  KWKTENVRRKHNYIPFLFNLLKALAEKKQLTPLVEK 321
           **********************************98 PP

Organism

Aegilops tauschii

Protein Sequence
(Fasta)

MSWCTIESDP GVFTELIQEM QVKGVQVEEL YSLDVDSLSQ LQPVYGLIFL FKWMPGGNDE 60
RPVVSDPNPN LFFARQVITN ACATQAILSI LMNRPEIDIG PELSNLKEFT GAFAPDMKGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGTGGT GCACCATCGA GTCTGATCCC GGTAAGCGCA ACGTCTCACC AGAAAATTTA 60
CCCTGCTTTT CTTACCTAGA TTAGCTGTAT GTGCTCGGAT TACATGCTTC GCTAGCTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0378--Hydrolase
KW-0645--Protease
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ats:F775_11663

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001866	Ailuropoda melanoleuca	47.69	2.00e-83	301.00
IUUC-Atr-002966	Amborella trichopoda	69.97	2.00e-131	461.00
IUUC-Apl-003306	Anas platyrhynchos	43.10	1.00e-76	279.00
IUUC-Aca-004763	Anolis carolinensis	46.77	2.00e-81	295.00
IUUC-Aly-005581	Arabidopsis lyrata	73.39	1.00e-128	451.00
IUUC-Ath-007283	Arabidopsis thaliana	74.92	5.00e-134	469.00
IUUC-Ago-007999	Ashbya gossypii	35.63	5.00e-34	137.00
IUUC-Acl-008231	Aspergillus clavatus	48.74	2.00e-58	218.00
IUUC-Afl-008557	Aspergillus flavus	40.31	5.00e-57	213.00
IUUC-Afu-008988	Aspergillus fumigatus	49.80	8.00e-61	226.00
IUUC-Ani-009420	Aspergillus nidulans	41.19	1.00e-59	222.00
IUUC-Ang-009859	Aspergillus niger	42.21	4.00e-56	211.00
IUUC-Aor-010145	Aspergillus oryzae	40.31	5.00e-57	213.00
IUUC-Ate-010347	Aspergillus terreus	45.28	8.00e-56	209.00
IUUC-Ame-010791	Astyanax mexicanus	46.25	7.00e-84	303.00
IUUC-Bgr-012298	Blumeria graminis	39.57	4.00e-54	204.00
IUUC-Bta-013251	Bos taurus	48.14	9.00e-83	299.00
IUUC-Bci-013786	Botrytis cinerea	39.52	3.00e-59	221.00
IUUC-Bdi-014132	Brachypodium distachyon	89.79	4.00e-166	576.00
IUUC-Bol-015611	Brassica oleracea	74.39	4.00e-137	479.00
IUUC-Bra-017769	Brassica rapa	74.39	2.00e-136	477.00
IUUC-Cel-018604	Caenorhabditis elegans	41.85	6.00e-69	253.00
IUUC-Cja-019768	Callithrix jacchus	44.23	4.00e-78	284.00
IUUC-Cfa-020207	Canis familiaris	47.69	2.00e-83	301.00
IUUC-Cpo-021925	Cavia porcellus	45.85	2.00e-79	288.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	52.74	4.00e-84	303.00
IUUC-Csa-023958	Chlorocebus sabaeus	48.14	1.00e-82	299.00
IUUC-Cho-024928	Choloepus hoffmanni	52.70	1.00e-16	79.30
IUUC-Cin-025771	Ciona intestinalis	41.34	9.00e-69	253.00
IUUC-Csv-026149	Ciona savignyi	42.60	3.00e-71	261.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	35.22	2.00e-47	182.00
IUUC-Cne-026955	Cryptococcus neoformans	33.73	1.00e-48	186.00
IUUC-Cme-027104	Cyanidioschyzon merolae	30.99	8.00e-47	180.00
IUUC-Dre-027409	Danio rerio	46.25	7.00e-83	299.00
IUUC-Dno-028921	Dasypus novemcinctus	47.69	4.00e-83	300.00
IUUC-Dor-030891	Dipodomys ordii	38.46	1.00e-40	160.00
IUUC-Dse-031170	Dothistroma septosporum	41.77	9.00e-63	233.00
IUUC-Dme-031677	Drosophila melanogaster	48.47	6.00e-82	296.00
IUUC-Ete-032646	Echinops telfairi	43.44	3.00e-43	169.00
IUUC-Eca-033776	Equus caballus	46.75	7.00e-75	273.00
IUUC-Eeu-035305	Erinaceus europaeus	43.41	1.00e-36	146.00
IUUC-Fca-035846	Felis catus	44.03	7.00e-79	286.00
IUUC-Fal-037597	Ficedula albicollis	46.20	5.00e-71	260.00
IUUC-Fox-037670	Fusarium oxysporum	47.16	4.00e-50	191.00
IUUC-Fso-038243	Fusarium solani	46.96	8.00e-50	189.00
IUUC-Gmo-038499	Gadus morhua	44.00	7.00e-74	270.00
IUUC-Ggr-039975	Gaeumannomyces graminis	42.80	4.00e-51	194.00
IUUC-Gga-040904	Gallus gallus	47.59	1.00e-84	305.00
IUUC-Gac-042058	Gasterosteus aculeatus	46.77	8.00e-82	296.00
IUUC-Gma-043030	Glycine max	74.62	7.00e-142	495.00
IUUC-Ggo-044699	Gorilla gorilla	44.51	7.00e-71	259.00
IUUC-Hsa-046227	Homo sapiens	48.32	6.00e-84	303.00
IUUC-Hvu-047359	Hordeum vulgare	97.24	0.00e+00	628.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	43.82	2.00e-78	285.00
IUUC-Lch-049829	Latimeria chalumnae	47.69	6.00e-83	300.00
IUUC-Lpe-050899	Leersia perrieri	85.94	8.00e-146	508.00
IUUC-Loc-052264	Lepisosteus oculatus	46.32	3.00e-80	291.00
IUUC-Lma-053110	Leptosphaeria maculans	50.87	2.00e-52	199.00
IUUC-Laf-053639	Loxodonta africana	47.69	2.00e-83	301.00
IUUC-Mcc-055506	Macaca mulatta	48.14	1.00e-82	299.00
IUUC-Meu-056267	Macropus eugenii	43.13	7.00e-51	194.00
IUUC-Mor-057001	Magnaporthe oryzae	45.31	2.00e-52	198.00
IUUC-Mpo-057608	Magnaporthe poae	43.41	3.00e-36	144.00
IUUC-Mtr-057731	Medicago truncatula	74.32	1.00e-138	484.00
IUUC-Mla-059016	Melampsora laricipopulina	47.24	3.00e-47	180.00
IUUC-Mga-060178	Meleagris gallopavo	46.01	3.00e-76	277.00
IUUC-Mvi-060353	Microbotryum violaceum	38.72	3.00e-57	214.00
IUUC-Mmr-060738	Microcebus murinus	48.62	4.00e-84	303.00
IUUC-Mdo-062266	Monodelphis domestica	51.44	2.00e-57	214.00
IUUC-Mmu-063619	Mus musculus	48.00	1.00e-83	302.00
IUUC-Mac-065301	Musa acuminata	74.77	2.00e-144	504.00
IUUC-Mpu-066058	Mustela putorius furo	47.69	2.00e-83	301.00
IUUC-Mlu-067292	Myotis lucifugus	48.15	5.00e-84	303.00
IUUC-Nfi-068275	Neosartorya fischeri	39.88	1.00e-60	226.00
IUUC-Ncr-068713	Neurospora crassa	39.27	6.00e-58	216.00
IUUC-Nle-069013	Nomascus leucogenys	48.45	2.00e-83	301.00
IUUC-Opr-070628	Ochotona princeps	42.17	2.00e-72	265.00
IUUC-Ont-072688	Oreochromis niloticus	45.87	5.00e-80	290.00
IUUC-Oan-073004	Ornithorhynchus anatinus	49.55	7.00e-60	223.00
IUUC-Ocu-074303	Oryctolagus cuniculus	47.69	4.00e-83	301.00
IUUC-Oba-075002	Oryza barthii	83.18	3.00e-154	536.00
IUUC-Obr-076392	Oryza brachyantha	83.75	3.00e-148	516.00
IUUC-Ogl-077271	Oryza glaberrima	83.18	3.00e-154	536.00
IUUC-Ogu-078493	Oryza glumaepatula	83.48	3.00e-155	540.00
IUUC-Oin-080084	Oryza indica	83.48	3.00e-155	540.00
IUUC-Olo-080803	Oryza longistaminata	83.18	7.00e-155	538.00
IUUC-Ome-081146	Oryza meridionalis	82.58	1.00e-153	535.00
IUUC-Oni-082146	Oryza nivara	83.48	3.00e-155	540.00
IUUC-Opu-083633	Oryza punctata	82.81	2.00e-148	517.00
IUUC-Oru-084789	Oryza rufipogon	83.48	3.00e-155	540.00
IUUC-Osa-086196	Oryza sativa	83.48	3.00e-155	540.00
IUUC-Ola-087126	Oryzias latipes	46.77	2.00e-80	291.00
IUUC-Olu-087665	Ostreococcus lucimarinus	46.20	4.00e-73	267.00
IUUC-Oga-089140	Otolemur garnettii	44.92	2.00e-79	288.00
IUUC-Oar-090296	Ovis aries	47.84	1.00e-82	298.00
IUUC-Ptr-090566	Pan troglodytes	48.32	6.00e-84	303.00
IUUC-Pan-092052	Papio anubis	48.14	1.00e-82	299.00
IUUC-Psi-093723	Pelodiscus sinensis	47.52	5.00e-74	270.00
IUUC-Pma-094568	Petromyzon marinus	41.53	6.00e-62	230.00
IUUC-Pno-095120	Phaeosphaeria nodorum	48.93	5.00e-53	200.00
IUUC-Ppa-095761	Physcomitrella patens	68.62	1.00e-131	461.00
IUUC-Pfo-096210	Poecilia formosa	46.77	1.00e-81	295.00
IUUC-Pab-098463	Pongo abelii	48.32	1.00e-83	302.00
IUUC-Pop-099109	Populus trichocarpa	73.00	1.00e-140	491.00
IUUC-Pca-100108	Procavia capensis	50.62	5.00e-66	243.00
IUUC-Ppe-101176	Prunus persica	76.90	7.00e-142	495.00
IUUC-Pva-102629	Pteropus vampyrus	48.48	5.00e-68	250.00
IUUC-Pgr-103419	Puccinia graminis	48.95	7.00e-59	219.00
IUUC-Pte-104207	Pyrenophora teres	52.12	9.00e-39	151.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	41.38	2.00e-58	218.00
IUUC-Rno-105579	Rattus norvegicus	41.35	1.00e-70	259.00
IUUC-Sha-106894	Sarcophilus harrisii	46.37	4.00e-70	257.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	43.53	4.00e-65	240.00
IUUC-Spo-108371	Schizosaccharomyces pombe	44.83	3.00e-69	254.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	36.39	1.00e-46	179.00
IUUC-Smo-109396	Selaginella moellendorffii	68.90	3.00e-124	437.00
IUUC-Sit-110630	Setaria italica	81.96	3.00e-151	526.00
IUUC-Sly-110972	Solanum lycopersicum	74.19	4.00e-136	476.00
IUUC-Stu-112185	Solanum tuberosum	75.38	6.00e-148	515.00
IUUC-Sar-113294	Sorex araneus	41.11	1.00e-70	259.00
IUUC-Sbi-113951	Sorghum bicolor	82.57	2.00e-150	524.00
IUUC-Ssc-115501	Sus scrofa	46.20	7.00e-77	279.00
IUUC-Tgu-117152	Taeniopygia guttata	46.20	5.00e-71	260.00
IUUC-Tru-118388	Takifugu rubripes	45.85	5.00e-81	293.00
IUUC-Tsy-119109	Tarsius syrichta	48.32	9.00e-84	302.00
IUUC-Tni-120048	Tetraodon nigroviridis	45.85	5.00e-81	293.00
IUUC-Tca-121750	Theobroma cacao	74.70	1.00e-146	511.00
IUUC-Tre-122130	Trichoderma reesei	37.90	2.00e-54	204.00
IUUC-Tvi-122284	Trichoderma virens	37.66	3.00e-50	191.00
IUUC-Tae-124082	Triticum aestivum	98.16	0.00e+00	638.00
IUUC-Tme-127187	Tuber melanosporum	41.61	2.00e-65	241.00
IUUC-Tbe-127619	Tupaia belangeri	41.56	3.00e-56	211.00
IUUC-Ttr-128867	Tursiops truncatus	44.53	4.00e-55	207.00
IUUC-Vda-129912	Verticillium dahliae	39.14	6.00e-56	210.00
IUUC-Vpa-130552	Vicugna pacos	51.69	2.00e-57	215.00
IUUC-Vvi-130881	Vitis vinifera	75.08	2.00e-140	491.00
IUUC-Xtr-131934	Xenopus tropicalis	47.73	5.00e-86	310.00
IUUC-Xma-133312	Xiphophorus maculatus	46.77	1.00e-81	295.00
IUUC-Yli-134487	Yarrowia lipolytica	43.40	1.00e-51	196.00
IUUC-Zma-135639	Zea mays	70.43	5.00e-136	476.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence