iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ncr-068713

Ensembl Protein ID

EAA32244

UniProt Accession

Q1K7Z3; Q1K7Z3_NEUCR

Genbank Protein ID

EAA32244.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

CM002240

Gene Name

NCU03704

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
NCU03704	EAA32244	EAA32244

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	1.90e-60	204.0	4	244

Active Site

Position(s)	Description	Evidence
91	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
178	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAllsv 107
           +w ++esd+g+ft+l+ ++gvk++ q+eel sL+p+ l+++ +pv+g+++lFk+  ++  + + + + +   + d+d+ + +ffa+q+i+N+C+t+Allsv
   Q: 4    GWNTIESDAGVFTDLLTNLGVKGV-QFEELLSLEPDALAQL-HPVYGVIFLFKYPTNEPYRGTDKPL-D--GTFDYDASERLFFAHQTIQNACGTQALLSV 99
           8***********************.****************.***********86655555544433.4..799*************************** PP
   S: 108  llnc.........edklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglkpf 199
           lln          + + +d+G++l  ++++t a  +e +++al+n++ ++ +hns+ar+ ++  ++++  d+   + +afhf++y +i+g lyeldgl+p+
   Q: 100  LLNKadpsvsqegDAGYIDIGDKLRDFRDFTIALPAEIRGEALSNSELIRDTHNSFARSSPFIDETQRRPDE--EEGDAFHFIAYSPIGGTLYELDGLQPA 198
           ****9***9998555559********************************************9998876664..589************************ PP
   S: 200  Pldlgkkketeelkdklkvvraflerikllesdeirfnllaivadrrvi 248
           P+ +g+++ +e++ +k+  v     ri  +++ eirfnlla+  d r+ 
   Q: 199  PISHGACT-QEDFPQKVMDVL--QRRIARYDASEIRFNLLAMIRDLRIR 244
           ******65.677778877777..7********************98873 PP

Organism

Neurospora crassa

Protein Sequence
(Fasta)

MSGGWNTIES DAGVFTDLLT NLGVKGVQFE ELLSLEPDAL AQLHPVYGVI FLFKYPTNEP 60
YRGTDKPLDG TFDYDASERL FFAHQTIQNA CGTQALLSVL LNKADPSVSQ EGDAGYIDIG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGAGCTGCA TCATCGCATT GAACATTCGC CGTAACGTTT GCAGTTGTAG CTTGTTGCCG 60
TACGGAGTTG GAACGATTGA TATTATTTCT GTGTTCAGCA GCATCTATGT CCGCCAGCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0034399--C:nuclear periphery
GO:0031595--C:nuclear proteasome complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ncr:NCU03704

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	39.27	3.00e-58	216.00
IUUC-Aml-001866	Ailuropoda melanoleuca	38.80	3.00e-58	217.00
IUUC-Atr-002966	Amborella trichopoda	37.57	3.00e-51	193.00
IUUC-Apl-003306	Anas platyrhynchos	36.20	3.00e-51	193.00
IUUC-Aca-004763	Anolis carolinensis	38.80	5.00e-58	216.00
IUUC-Aly-005581	Arabidopsis lyrata	40.00	1.00e-53	201.00
IUUC-Ath-007283	Arabidopsis thaliana	39.09	7.00e-55	205.00
IUUC-Ago-007999	Ashbya gossypii	38.36	7.00e-44	169.00
IUUC-Acl-008231	Aspergillus clavatus	59.49	1.00e-102	364.00
IUUC-Afl-008557	Aspergillus flavus	61.09	4.00e-105	372.00
IUUC-Afu-008988	Aspergillus fumigatus	59.37	1.00e-102	364.00
IUUC-Ani-009420	Aspergillus nidulans	60.00	8.00e-102	361.00
IUUC-Ang-009859	Aspergillus niger	59.55	3.00e-94	336.00
IUUC-Aor-010145	Aspergillus oryzae	61.09	4.00e-105	372.00
IUUC-Ate-010347	Aspergillus terreus	56.84	3.00e-95	339.00
IUUC-Ame-010791	Astyanax mexicanus	38.36	8.00e-58	215.00
IUUC-Bgr-012298	Blumeria graminis	59.81	3.00e-106	376.00
IUUC-Bta-013251	Bos taurus	38.92	2.00e-57	214.00
IUUC-Bci-013786	Botrytis cinerea	67.07	3.00e-127	446.00
IUUC-Bdi-014132	Brachypodium distachyon	44.70	5.00e-54	202.00
IUUC-Bol-015611	Brassica oleracea	39.82	2.00e-54	204.00
IUUC-Bra-017769	Brassica rapa	39.21	3.00e-54	203.00
IUUC-Cel-018604	Caenorhabditis elegans	38.41	4.00e-52	196.00
IUUC-Cja-019768	Callithrix jacchus	35.76	5.00e-53	199.00
IUUC-Cfa-020207	Canis familiaris	38.80	3.00e-58	217.00
IUUC-Cpo-021925	Cavia porcellus	36.91	1.00e-52	197.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	48.72	9.00e-56	208.00
IUUC-Csa-023958	Chlorocebus sabaeus	39.17	6.00e-58	216.00
IUUC-Cho-024928	Choloepus hoffmanni	39.08	6.00e-10	56.20
IUUC-Cin-025771	Ciona intestinalis	37.46	3.00e-52	196.00
IUUC-Csv-026149	Ciona savignyi	36.14	1.00e-51	194.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	57.99	2.00e-102	363.00
IUUC-Cne-026955	Cryptococcus neoformans	34.43	2.00e-48	184.00
IUUC-Cme-027104	Cyanidioschyzon merolae	34.37	3.00e-45	173.00
IUUC-Dre-027409	Danio rerio	38.68	6.00e-58	215.00
IUUC-Dno-028921	Dasypus novemcinctus	38.49	1.00e-57	214.00
IUUC-Dor-030891	Dipodomys ordii	32.42	8.00e-29	120.00
IUUC-Dse-031170	Dothistroma septosporum	59.82	1.00e-107	380.00
IUUC-Dme-031677	Drosophila melanogaster	37.34	9.00e-49	185.00
IUUC-Ete-032646	Echinops telfairi	37.21	7.00e-29	120.00
IUUC-Eca-033776	Equus caballus	38.18	2.00e-51	194.00
IUUC-Eeu-035305	Erinaceus europaeus	36.18	8.00e-30	122.00
IUUC-Fca-035846	Felis catus	35.86	8.00e-54	202.00
IUUC-Fal-037597	Ficedula albicollis	38.51	3.00e-51	193.00
IUUC-Fox-037670	Fusarium oxysporum	69.81	8.00e-113	397.00
IUUC-Fso-038243	Fusarium solani	68.34	1.00e-111	394.00
IUUC-Gmo-038499	Gadus morhua	36.48	1.00e-50	191.00
IUUC-Ggr-039975	Gaeumannomyces graminis	69.03	6.00e-117	411.00
IUUC-Gga-040904	Gallus gallus	39.12	2.00e-59	220.00
IUUC-Gac-042058	Gasterosteus aculeatus	38.68	3.00e-57	213.00
IUUC-Gma-043030	Glycine max	40.18	5.00e-56	209.00
IUUC-Ggo-044699	Gorilla gorilla	42.54	9.00e-56	208.00
IUUC-Hsa-046227	Homo sapiens	39.12	1.00e-58	218.00
IUUC-Hvu-047359	Hordeum vulgare	38.97	1.00e-57	214.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	35.73	2.00e-53	201.00
IUUC-Lch-049829	Latimeria chalumnae	38.80	2.00e-59	220.00
IUUC-Lpe-050899	Leersia perrieri	39.14	6.00e-57	212.00
IUUC-Loc-052264	Lepisosteus oculatus	37.62	5.00e-56	209.00
IUUC-Lma-053110	Leptosphaeria maculans	64.90	3.00e-100	356.00
IUUC-Laf-053639	Loxodonta africana	38.80	3.00e-58	217.00
IUUC-Mcc-055506	Macaca mulatta	39.49	5.00e-58	216.00
IUUC-Meu-056267	Macropus eugenii	37.07	2.00e-36	145.00
IUUC-Mor-057001	Magnaporthe oryzae	67.06	3.00e-113	399.00
IUUC-Mpo-057608	Magnaporthe poae	74.05	1.00e-71	260.00
IUUC-Mtr-057731	Medicago truncatula	38.69	8.00e-59	218.00
IUUC-Mla-059016	Melampsora laricipopulina	42.99	9.00e-43	164.00
IUUC-Mga-060178	Meleagris gallopavo	38.51	1.00e-52	197.00
IUUC-Mvi-060353	Microbotryum violaceum	36.05	2.00e-54	204.00
IUUC-Mmr-060738	Microcebus murinus	38.49	6.00e-58	215.00
IUUC-Mdo-062266	Monodelphis domestica	44.84	9.00e-49	184.00
IUUC-Mmu-063619	Mus musculus	39.62	4.00e-59	219.00
IUUC-Mac-065301	Musa acuminata	42.63	9.00e-62	228.00
IUUC-Mpu-066058	Mustela putorius furo	38.80	2.00e-58	217.00
IUUC-Mlu-067292	Myotis lucifugus	39.24	2.00e-58	217.00
IUUC-Nfi-068275	Neosartorya fischeri	60.00	5.00e-111	392.00
IUUC-Nle-069013	Nomascus leucogenys	39.05	1.00e-57	214.00
IUUC-Opr-070628	Ochotona princeps	34.21	9.00e-50	188.00
IUUC-Ont-072688	Oreochromis niloticus	38.49	4.00e-58	216.00
IUUC-Oan-073004	Ornithorhynchus anatinus	41.87	4.00e-49	186.00
IUUC-Ocu-074303	Oryctolagus cuniculus	38.92	1.00e-57	215.00
IUUC-Oba-075002	Oryza barthii	37.46	4.00e-56	209.00
IUUC-Obr-076392	Oryza brachyantha	38.37	6.00e-58	216.00
IUUC-Ogl-077271	Oryza glaberrima	37.46	4.00e-56	209.00
IUUC-Ogu-078493	Oryza glumaepatula	37.76	4.00e-57	213.00
IUUC-Oin-080084	Oryza indica	37.76	4.00e-57	213.00
IUUC-Olo-080803	Oryza longistaminata	37.76	4.00e-57	213.00
IUUC-Ome-081146	Oryza meridionalis	37.76	8.00e-57	212.00
IUUC-Oni-082146	Oryza nivara	37.76	4.00e-57	213.00
IUUC-Opu-083633	Oryza punctata	37.76	2.00e-56	211.00
IUUC-Oru-084789	Oryza rufipogon	37.76	4.00e-57	213.00
IUUC-Osa-086196	Oryza sativa	37.76	4.00e-57	213.00
IUUC-Ola-087126	Oryzias latipes	38.80	2.00e-58	217.00
IUUC-Olu-087665	Ostreococcus lucimarinus	42.71	2.00e-57	213.00
IUUC-Oga-089140	Otolemur garnettii	36.05	2.00e-53	201.00
IUUC-Oar-090296	Ovis aries	38.36	2.00e-56	211.00
IUUC-Ptr-090566	Pan troglodytes	39.12	1.00e-58	218.00
IUUC-Pan-092052	Papio anubis	39.17	6.00e-58	216.00
IUUC-Psi-093723	Pelodiscus sinensis	38.51	3.00e-52	196.00
IUUC-Pma-094568	Petromyzon marinus	44.63	3.00e-49	186.00
IUUC-Pno-095120	Phaeosphaeria nodorum	61.35	3.00e-102	363.00
IUUC-Ppa-095761	Physcomitrella patens	38.90	8.00e-55	205.00
IUUC-Pfo-096210	Poecilia formosa	38.80	3.00e-58	216.00
IUUC-Pab-098463	Pongo abelii	39.24	1.00e-58	218.00
IUUC-Pop-099109	Populus trichocarpa	40.00	1.00e-55	208.00
IUUC-Pca-100108	Procavia capensis	43.32	2.00e-52	197.00
IUUC-Ppe-101176	Prunus persica	40.00	4.00e-54	202.00
IUUC-Pva-102629	Pteropus vampyrus	44.08	3.00e-53	199.00
IUUC-Pgr-103419	Puccinia graminis	37.57	2.00e-50	190.00
IUUC-Pte-104207	Pyrenophora teres	60.22	2.00e-54	202.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	61.35	4.00e-107	379.00
IUUC-Rno-105579	Rattus norvegicus	36.96	1.00e-50	191.00
IUUC-Sha-106894	Sarcophilus harrisii	37.77	2.00e-46	177.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	45.23	2.00e-76	276.00
IUUC-Spo-108371	Schizosaccharomyces pombe	51.36	7.00e-81	291.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	66.11	2.00e-107	379.00
IUUC-Smo-109396	Selaginella moellendorffii	39.27	1.00e-52	197.00
IUUC-Sit-110630	Setaria italica	45.42	9.00e-58	215.00
IUUC-Sly-110972	Solanum lycopersicum	38.17	3.00e-50	189.00
IUUC-Stu-112185	Solanum tuberosum	39.10	3.00e-58	216.00
IUUC-Sar-113294	Sorex araneus	33.14	2.00e-45	174.00
IUUC-Sbi-113951	Sorghum bicolor	46.56	6.00e-58	216.00
IUUC-Ssc-115501	Sus scrofa	37.70	1.00e-53	201.00
IUUC-Tgu-117152	Taeniopygia guttata	38.51	3.00e-51	193.00
IUUC-Tru-118388	Takifugu rubripes	38.68	3.00e-57	213.00
IUUC-Tsy-119109	Tarsius syrichta	38.92	2.00e-58	217.00
IUUC-Tni-120048	Tetraodon nigroviridis	38.68	1.00e-57	214.00
IUUC-Tca-121750	Theobroma cacao	39.47	2.00e-58	217.00
IUUC-Tre-122130	Trichoderma reesei	68.06	9.00e-119	417.00
IUUC-Tvi-122284	Trichoderma virens	70.92	9.00e-115	404.00
IUUC-Tae-124082	Triticum aestivum	39.27	4.00e-58	216.00
IUUC-Tur-126366	Triticum urartu	38.82	6.00e-39	153.00
IUUC-Tme-127187	Tuber melanosporum	61.47	9.00e-115	404.00
IUUC-Tbe-127705	Tupaia belangeri	38.22	1.00e-34	138.00
IUUC-Ttr-128867	Tursiops truncatus	39.20	5.00e-43	166.00
IUUC-Vda-129912	Verticillium dahliae	62.89	5.00e-104	369.00
IUUC-Vpa-130552	Vicugna pacos	43.95	3.00e-48	183.00
IUUC-Vvi-130881	Vitis vinifera	39.10	5.00e-53	199.00
IUUC-Xtr-131934	Xenopus tropicalis	36.79	3.00e-54	203.00
IUUC-Xma-133312	Xiphophorus maculatus	38.80	3.00e-58	216.00
IUUC-Yli-134487	Yarrowia lipolytica	43.65	1.00e-70	258.00
IUUC-Zma-135639	Zea mays	39.46	7.00e-48	182.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence