iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-017760

Ensembl Protein ID

Bra033012.1-P

UniProt Accession

M4EW29; M4EW29_BRARP

Protein Name

Eukaryotic translation initiation factor 3 subunit I

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra033012	Bra033012.1	Bra033012.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-22	80.3	357	394
UBD/Beta-Prp	6.80e-46	157.8	313	542

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH++ v+c++   d  +l++Gs D + k+WD++tg +l
   Q: 357  GHNGAVWCCDVsRDsLRLITGSADQSAKLWDVKTGQQL 394
           8***********77799*****************9876 PP

UBD/Beta-Prp

   S: 48   lsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee............ 131
           ++ghe + t +++++dg++l ++++D+t  +w  ++g+   t++gh+  v+++++s+++ +l++Gs+d+ +++wd++tgq l +            
   Q: 313  MKGHERPLTFLRYNRDGDMLFSCAKDHTPTLWYADNGERHGTFRGHNGAVWCCDVSRDSLRLITGSADQSAKLWDVKTGQQLFSfkfgsparsvdf 408
           388999999999999999999999999999999999999999999999999999999889999999999999999999999988899999999999 PP
   S: 132  ..........................................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl..tgghtdsv 183
                                                       +  ++ +n +v+ p ++ +vsG+ D ++r+Wd +tgkll++   + gh++ +
   Q: 409  algdklavittdpfmertsaihvkriaedpedqvsesvlvleSPN-GRKRINRAVWGPLNQTIVSGGEDAVLRIWDAETGKLLKESdsEVGHKNTI 503
           9999999999999999999999999999999999999**974444.455889999*******************************99667***** PP
   S: 184  yslsfdsngkelvsgsldgtvk..lwdlqtgecvrtlng 220
           +sl+ + +  ++++gsld+t k  lwd++t + ++t+  
   Q: 504  TSLTKSADDSHFITGSLDKTAKacLWDMRTLTLLKTYVS 542
           ********************99779*****999999975 PP

Organism

Brassica rapa

Functional Description
(View)

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

Protein Sequence
(Fasta)

MSSTPDITGI LENTKELDRL RKEQEEVLVE VNKIHKKLRS SPEVVEKPGD TSLSQLKNLF 60
IQAKELSESE VTVSNIRLAQ LDSLLPSGQQ RGKLEVAEGN GLKRKRMKAG SDVTRVPPSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGTCAA CGCCGGACAT AACAGGAATA CTGGAGAACA CGAAGGAACT TGATCGCTTA 60
CGTAAAGAAC AAGAAGAAGT TCTTGTCGAG GTCAATAAGA TACATAAGAA GCTTCGATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0396--Initiation factor
KW-0648--Protein biosynthesis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027525--eIF3i
IPR020472--G-protein_beta_WD-40_rep
IPR010750--SGF29_tudor-like_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS51518--SGF29_C
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07039--DUF1325
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016282--C:eukaryotic 43S preinitiation complex
GO:0033290--C:eukaryotic 48S preinitiation complex
GO:0005852--C:eukaryotic translation initiation factor 3 complex
GO:0003743--F:translation initiation factor activity
GO:0001731--P:formation of translation preinitiation complex
GO:0006446--P:regulation of translational initiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000115	Aegilops tauschii	56.98	5.00e-54	204.00
IUUC-Aml-001321	Ailuropoda melanoleuca	45.90	9.00e-82	296.00
IUUC-Atr-002468	Amborella trichopoda	70.83	1.00e-89	322.00
IUUC-Apl-003841	Anas platyrhynchos	46.50	2.00e-83	301.00
IUUC-Aca-005123	Anolis carolinensis	45.45	2.00e-84	305.00
IUUC-Aly-005473	Arabidopsis lyrata	86.36	4.00e-176	609.00
IUUC-Ath-007094	Arabidopsis thaliana	80.86	4.00e-174	603.00
IUUC-Ago-008000	Ashbya gossypii	43.45	3.00e-73	268.00
IUUC-Acl-008098	Aspergillus clavatus	44.05	1.00e-74	272.00
IUUC-Afl-008494	Aspergillus flavus	44.07	2.00e-77	282.00
IUUC-Afu-009080	Aspergillus fumigatus	42.69	2.00e-73	269.00
IUUC-Ani-009230	Aspergillus nidulans	44.11	4.00e-76	277.00
IUUC-Aor-010114	Aspergillus oryzae	44.07	2.00e-77	282.00
IUUC-Ate-010285	Aspergillus terreus	44.41	2.00e-77	281.00
IUUC-Ame-011534	Astyanax mexicanus	45.02	3.00e-83	301.00
IUUC-Bgr-012121	Blumeria graminis	41.95	2.00e-69	255.00
IUUC-Bta-013143	Bos taurus	46.06	2.00e-82	298.00
IUUC-Bci-013950	Botrytis cinerea	45.15	2.00e-77	282.00
IUUC-Bdi-015019	Brachypodium distachyon	75.76	1.00e-151	528.00
IUUC-Bol-015709	Brassica oleracea	80.97	0.00e+00	1011.00
IUUC-Cja-019741	Callithrix jacchus	46.06	1.00e-82	299.00
IUUC-Cfa-021204	Canis familiaris	45.90	6.00e-82	296.00
IUUC-Cpo-021661	Cavia porcellus	45.59	1.00e-81	295.00
IUUC-Cre-022952	Chlamydomonas reinhardtii	50.91	2.00e-101	361.00
IUUC-Csa-024038	Chlorocebus sabaeus	46.06	1.00e-82	299.00
IUUC-Cin-025597	Ciona intestinalis	45.45	5.00e-82	297.00
IUUC-Cgl-026583	Colletotrichum gloeosporioides	44.85	8.00e-76	276.00
IUUC-Cne-026838	Cryptococcus neoformans	40.48	1.00e-74	272.00
IUUC-Dre-028567	Danio rerio	44.85	1.00e-84	306.00
IUUC-Dno-029171	Dasypus novemcinctus	45.90	2.00e-81	295.00
IUUC-Dse-031191	Dothistroma septosporum	45.24	8.00e-78	283.00
IUUC-Dme-031879	Drosophila melanogaster	46.32	7.00e-87	313.00
IUUC-Ete-032336	Echinops telfairi	39.37	2.00e-38	151.00
IUUC-Eca-033259	Equus caballus	45.90	8.00e-82	296.00
IUUC-Eeu-035153	Erinaceus europaeus	41.01	2.00e-21	95.90
IUUC-Fca-036489	Felis catus	45.90	8.00e-82	296.00
IUUC-Fal-037485	Ficedula albicollis	46.20	3.00e-83	301.00
IUUC-Fox-037860	Fusarium oxysporum	44.11	4.00e-74	271.00
IUUC-Fso-038188	Fusarium solani	44.11	9.00e-74	270.00
IUUC-Gmo-039311	Gadus morhua	44.68	2.00e-82	298.00
IUUC-Ggr-040045	Gaeumannomyces graminis	43.47	3.00e-74	271.00
IUUC-Gga-040645	Gallus gallus	45.56	5.00e-82	297.00
IUUC-Gac-042086	Gasterosteus aculeatus	44.55	7.00e-82	296.00
IUUC-Gma-043246	Glycine max	83.64	5.00e-169	586.00
IUUC-Ggo-045578	Gorilla gorilla	46.06	1.00e-82	299.00
IUUC-Hsa-046734	Homo sapiens	46.06	1.00e-82	299.00
IUUC-Hvu-047553	Hordeum vulgare	75.76	2.00e-151	528.00
IUUC-Itr-048467	Ictidomys tridecemlineatus	45.90	1.00e-81	296.00
IUUC-Kpa-049325	Komagataella pastoris	43.77	2.00e-78	285.00
IUUC-Lch-049620	Latimeria chalumnae	45.57	3.00e-75	275.00
IUUC-Lpe-051338	Leersia perrieri	73.97	2.00e-141	494.00
IUUC-Loc-052094	Lepisosteus oculatus	40.30	5.00e-69	254.00
IUUC-Lma-053047	Leptosphaeria maculans	47.11	2.00e-81	295.00
IUUC-Laf-053801	Loxodonta africana	45.82	3.00e-79	288.00
IUUC-Mcc-055498	Macaca mulatta	40.61	2.00e-63	235.00
IUUC-Meu-056729	Macropus eugenii	42.30	8.00e-73	266.00
IUUC-Mor-057025	Magnaporthe oryzae	43.03	1.00e-71	263.00
IUUC-Mpo-057511	Magnaporthe poae	45.15	4.00e-75	274.00
IUUC-Mtr-058051	Medicago truncatula	83.33	3.00e-169	587.00
IUUC-Mla-059061	Melampsora laricipopulina	43.43	8.00e-75	273.00
IUUC-Mga-059229	Meleagris gallopavo	45.92	5.00e-81	293.00
IUUC-Mmr-060764	Microcebus murinus	46.06	7.00e-83	300.00
IUUC-Mdo-062088	Monodelphis domestica	45.76	2.00e-82	298.00
IUUC-Mmu-064304	Mus musculus	45.76	2.00e-82	298.00
IUUC-Mac-065520	Musa acuminata	77.54	2.00e-155	541.00
IUUC-Mpu-066340	Mustela putorius furo	45.90	8.00e-82	296.00
IUUC-Mlu-067111	Myotis lucifugus	45.90	6.00e-82	296.00
IUUC-Nfi-068478	Neosartorya fischeri	42.69	3.00e-74	271.00
IUUC-Ncr-068820	Neurospora crassa	43.94	2.00e-73	268.00
IUUC-Nle-069903	Nomascus leucogenys	45.90	4.00e-82	297.00
IUUC-Opr-070221	Ochotona princeps	44.85	5.00e-80	290.00
IUUC-Ont-071765	Oreochromis niloticus	45.15	7.00e-85	306.00
IUUC-Oan-073660	Ornithorhynchus anatinus	44.75	9.00e-70	256.00
IUUC-Ocu-074039	Oryctolagus cuniculus	45.90	6.00e-82	296.00
IUUC-Oba-075395	Oryza barthii	71.21	2.00e-138	484.00
IUUC-Obr-076334	Oryza brachyantha	74.24	4.00e-145	506.00
IUUC-Ogl-077751	Oryza glaberrima	77.88	4.00e-156	543.00
IUUC-Ogu-078207	Oryza glumaepatula	76.29	2.00e-152	531.00
IUUC-Oin-079878	Oryza indica	76.67	4.00e-153	533.00
IUUC-Olo-080677	Oryza longistaminata	64.58	2.00e-141	495.00
IUUC-Oni-082411	Oryza nivara	68.48	1.00e-130	458.00
IUUC-Opu-083136	Oryza punctata	77.58	1.00e-155	541.00
IUUC-Oru-084916	Oryza rufipogon	74.93	2.00e-151	528.00
IUUC-Osa-085776	Oryza sativa	77.88	4.00e-156	543.00
IUUC-Ola-087053	Oryzias latipes	44.85	8.00e-83	300.00
IUUC-Olu-087602	Ostreococcus lucimarinus	60.79	8.00e-117	412.00
IUUC-Oga-088154	Otolemur garnettii	46.20	1.00e-82	299.00
IUUC-Oar-089915	Ovis aries	45.90	1.00e-81	296.00
IUUC-Ptr-091124	Pan troglodytes	36.89	3.00e-55	208.00
IUUC-Pan-092035	Papio anubis	46.06	1.00e-82	299.00
IUUC-Psi-094096	Pelodiscus sinensis	46.77	4.00e-48	183.00
IUUC-Pno-094988	Phaeosphaeria nodorum	42.55	1.00e-69	256.00
IUUC-Ppa-095536	Physcomitrella patens	71.82	2.00e-145	508.00
IUUC-Pfo-096101	Poecilia formosa	44.85	6.00e-84	303.00
IUUC-Pab-097726	Pongo abelii	46.06	1.00e-82	299.00
IUUC-Pop-099617	Populus trichocarpa	80.91	3.00e-163	566.00
IUUC-Pca-101014	Procavia capensis	46.06	1.00e-82	299.00
IUUC-Ppe-101320	Prunus persica	83.64	2.00e-170	590.00
IUUC-Pva-102789	Pteropus vampyrus	42.42	2.00e-70	259.00
IUUC-Pgr-103479	Puccinia graminis	38.97	9.00e-74	270.00
IUUC-Pte-104278	Pyrenophora teres	46.20	2.00e-77	281.00
IUUC-Pyt-104492	Pyrenophora triticirepentis	46.20	2.00e-77	281.00
IUUC-Rno-105867	Rattus norvegicus	41.99	6.00e-66	243.00
IUUC-Sce-106251	Saccharomyces cerevisiae	40.12	2.00e-70	258.00
IUUC-Sha-107039	Sarcophilus harrisii	45.76	2.00e-82	298.00
IUUC-Sja-107758	Schizosaccharomyces japonicus	43.20	3.00e-79	288.00
IUUC-Spo-108314	Schizosaccharomyces pombe	44.07	8.00e-83	300.00
IUUC-Ssl-108478	Sclerotinia sclerotiorum	44.55	1.00e-76	279.00
IUUC-Smo-108728	Selaginella moellendorffii	72.04	4.00e-143	500.00
IUUC-Sit-110801	Setaria italica	77.88	2.00e-154	537.00
IUUC-Sly-111326	Solanum lycopersicum	82.12	6.00e-166	575.00
IUUC-Stu-112458	Solanum tuberosum	83.33	7.00e-168	582.00
IUUC-Sbi-114063	Sorghum bicolor	76.06	3.00e-152	530.00
IUUC-Sre-115096	Sporisorium reilianum	41.35	6.00e-69	253.00
IUUC-Ssc-116080	Sus scrofa	46.06	1.00e-82	298.00
IUUC-Tgu-116988	Taeniopygia guttata	46.20	3.00e-83	301.00
IUUC-Tru-118766	Takifugu rubripes	44.85	5.00e-84	303.00
IUUC-Tni-120197	Tetraodon nigroviridis	45.15	2.00e-84	305.00
IUUC-Tca-121316	Theobroma cacao	82.73	8.00e-167	578.00
IUUC-Tre-122097	Trichoderma reesei	44.11	5.00e-74	270.00
IUUC-Tvi-122442	Trichoderma virens	43.50	4.00e-73	267.00
IUUC-Tae-125800	Triticum aestivum	73.49	4.00e-152	530.00
IUUC-Tur-126334	Triticum urartu	66.97	1.00e-126	445.00
IUUC-Tme-127038	Tuber melanosporum	45.02	1.00e-80	292.00
IUUC-Ttr-128659	Tursiops truncatus	42.73	5.00e-62	230.00
IUUC-Uma-129464	Ustilago maydis	41.35	3.00e-69	254.00
IUUC-Vda-129841	Verticillium dahliae	46.06	4.00e-76	277.00
IUUC-Vvi-131076	Vitis vinifera	81.52	1.00e-166	578.00
IUUC-Xtr-132395	Xenopus tropicalis	46.06	2.00e-84	305.00
IUUC-Xma-133383	Xiphophorus maculatus	44.85	9.00e-84	303.00
IUUC-Yli-134586	Yarrowia lipolytica	42.55	8.00e-68	249.00
IUUC-Zma-135904	Zea mays	76.97	1.00e-153	535.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence