iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000015488.1	ENSSHAT00000018392.1	ENSSHAP00000018242.1
ENSSHAG00000015488.1	ENSSHAT00000018393.1	ENSSHAP00000018243.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.00e-11	45.0	1116	1163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           + C+vC+++ged+ +l+ C++C+++fH  Cl ++   e p+ e w Cp C+
   Q: 1116 ARCKVCRKKGEDD-KLILCDECNKAFHLFCLRPA-LYEIPDGE-WQCPACQ 1163
           57*********98.6*******************.*******8.******7 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

EYEARLERYS ERIWTCKSTG SSQLTHKEAW EEEQEVAELL KEEFPAWYEK LVLEMVHHNT 60
ISLEKLVDSA WLEIMTKYAV GEECDFEVGK EKMLKVKIVA QDHQKKDPVI KEDEGRKDSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAGTATGAG GCCCGCTTGG AAAGATACAG TGAACGGATT TGGACGTGTA AGAGCACTGG 60
AAGCAGCCAG CTGACACACA AGGAGGCCTG GGAGGAAGAG CAGGAAGTGG CTGAGCTGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011989--ARM-like
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR018501--DDT_dom
IPR028942--WHIM1_dom
IPR028941--WHIM2_dom
IPR013136--WSTF_Acf1_Cbp146
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50827--DDT
PS51136--WAC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF10537--WAC_Acf1_DNA_bd
PF15612--WHIM1
PF15613--WSD

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00571--DDT
SM00249--PHD

Gene Ontology

GO:0000793--C:condensed chromosome
GO:0016604--C:nuclear body
GO:0043596--C:nuclear replication fork
GO:0005721--C:pericentric heterochromatin
GO:0003682--F:chromatin binding
GO:0035173--F:histone kinase activity
GO:0004713--F:protein tyrosine kinase activity
GO:0071884--F:vitamin D receptor activator activity
GO:0008270--F:zinc ion binding
GO:0006333--P:chromatin assembly or disassembly
GO:0048096--P:chromatin-mediated maintenance of transcription
GO:0006302--P:double-strand break repair
GO:0003007--P:heart morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002113	Ailuropoda melanoleuca	84.68	0.00e+00	2120.00
IUUC-Apl-003454	Anas platyrhynchos	77.90	0.00e+00	2059.00
IUUC-Ame-011469	Astyanax mexicanus	60.83	0.00e+00	1172.00
IUUC-Bta-012408	Bos taurus	84.33	0.00e+00	2114.00
IUUC-Cja-019194	Callithrix jacchus	82.95	0.00e+00	2092.00
IUUC-Cfa-021083	Canis familiaris	84.23	0.00e+00	2119.00
IUUC-Cpo-021422	Cavia porcellus	82.82	0.00e+00	2046.00
IUUC-Csa-023848	Chlorocebus sabaeus	84.61	0.00e+00	2144.00
IUUC-Dre-027895	Danio rerio	59.98	0.00e+00	1185.00
IUUC-Dno-029686	Dasypus novemcinctus	83.22	0.00e+00	2095.00
IUUC-Dor-030625	Dipodomys ordii	75.34	0.00e+00	1135.00
IUUC-Ete-032702	Echinops telfairi	86.59	0.00e+00	936.00
IUUC-Eca-033647	Equus caballus	84.61	0.00e+00	2168.00
IUUC-Eeu-034626	Erinaceus europaeus	80.56	0.00e+00	1830.00
IUUC-Fca-036092	Felis catus	86.84	0.00e+00	1889.00
IUUC-Fal-037127	Ficedula albicollis	77.50	0.00e+00	2023.00
IUUC-Gmo-039455	Gadus morhua	56.86	0.00e+00	1320.00
IUUC-Gga-041120	Gallus gallus	77.97	0.00e+00	1956.00
IUUC-Gac-041873	Gasterosteus aculeatus	56.81	0.00e+00	1359.00
IUUC-Ggo-045317	Gorilla gorilla	84.75	0.00e+00	2153.00
IUUC-Hsa-046773	Homo sapiens	84.68	0.00e+00	2135.00
IUUC-Itr-049026	Ictidomys tridecemlineatus	82.95	0.00e+00	2109.00
IUUC-Lch-050271	Latimeria chalumnae	69.44	0.00e+00	1586.00
IUUC-Loc-052699	Lepisosteus oculatus	65.33	0.00e+00	1029.00
IUUC-Mcc-055171	Macaca mulatta	84.54	0.00e+00	2141.00
IUUC-Meu-055990	Macropus eugenii	91.92	0.00e+00	2143.00
IUUC-Mga-059913	Meleagris gallopavo	77.97	0.00e+00	1921.00
IUUC-Mmr-061681	Microcebus murinus	84.47	0.00e+00	2119.00
IUUC-Mdo-062486	Monodelphis domestica	93.24	0.00e+00	2272.00
IUUC-Mmu-063460	Mus musculus	81.40	0.00e+00	1932.00
IUUC-Mpu-066324	Mustela putorius furo	84.56	0.00e+00	1108.00
IUUC-Mlu-067334	Myotis lucifugus	83.59	0.00e+00	2144.00
IUUC-Nle-069983	Nomascus leucogenys	84.75	0.00e+00	2165.00
IUUC-Opr-070678	Ochotona princeps	74.62	0.00e+00	689.00
IUUC-Ont-071565	Oreochromis niloticus	61.59	0.00e+00	976.00
IUUC-Ocu-074779	Oryctolagus cuniculus	84.40	0.00e+00	2105.00
IUUC-Ola-086746	Oryzias latipes	58.19	0.00e+00	1240.00
IUUC-Oga-088475	Otolemur garnettii	80.63	0.00e+00	2028.00
IUUC-Oar-090191	Ovis aries	82.62	0.00e+00	2073.00
IUUC-Ptr-090963	Pan troglodytes	84.55	0.00e+00	2111.00
IUUC-Pan-091819	Papio anubis	85.34	0.00e+00	1752.00
IUUC-Psi-093967	Pelodiscus sinensis	79.20	0.00e+00	1893.00
IUUC-Pfo-096939	Poecilia formosa	58.86	0.00e+00	1009.00
IUUC-Pab-098679	Pongo abelii	84.69	0.00e+00	1990.00
IUUC-Pop-099061	Populus trichocarpa	62.07	8.00e-09	54.30
IUUC-Pva-102969	Pteropus vampyrus	84.88	0.00e+00	1951.00
IUUC-Rno-104927	Rattus norvegicus	81.86	0.00e+00	1949.00
IUUC-Ssc-116243	Sus scrofa	84.40	0.00e+00	2122.00
IUUC-Tgu-117073	Taeniopygia guttata	77.77	0.00e+00	1809.00
IUUC-Tru-118265	Takifugu rubripes	57.39	0.00e+00	1281.00
IUUC-Ttr-128885	Tursiops truncatus	83.77	0.00e+00	1853.00
IUUC-Vvi-131714	Vitis vinifera	47.92	3.00e-12	65.90
IUUC-Xtr-131812	Xenopus tropicalis	65.81	0.00e+00	1325.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence