iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-066999

Ensembl Protein ID

ENSMLUP00000001536.2

UniProt Accession

G1NW53; G1NW53_MYOLU

Genbank Protein ID

ENSMLUP00000001536

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02010396

Gene Name

KLHL15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000001675.2	ENSMLUT00000001672.2	ENSMLUP00000001536.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	9.20e-18	64.4	4	68

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lv+++ +f+ahk+ La++S++F+ +f+ +++e++ ++++++k++ ++ f+++l+F+Y g++++
   Q: 4    DVTLVIDDHQFHAHKALLATQSDYFRIMFTADMRERD-QDKIHLKGLTATGFSHVLQFMYYGTIEL 68
           9***********************************9.************************9876 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

LLLDVTLVID DHQFHAHKAL LATQSDYFRI MFTADMRERD QDKIHLKGLT ATGFSHVLQF 60
MYYGTIELSM NTVHEILQAA MYVQLIEVVK FCCSFLLAKI CLENCAEIMR LLDDFGVNIE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCTGCTTG ATGTCACTCT GGTTATTGAC GACCATCAGT TCCATGCCCA TAAAGCACTT 60
TTGGCCACCC AGAGTGACTA CTTCAGAATT ATGTTTACTG CAGACATGCG GGAGCGTGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030597--KLHL15
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005634--C:nucleus
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0071630--P:ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001418	Ailuropoda melanoleuca	94.32	0.00e+00	975.00
IUUC-Apl-003970	Anas platyrhynchos	90.66	0.00e+00	946.00
IUUC-Aca-005217	Anolis carolinensis	90.11	0.00e+00	938.00
IUUC-Ame-011065	Astyanax mexicanus	83.15	0.00e+00	914.00
IUUC-Bta-012443	Bos taurus	94.32	0.00e+00	974.00
IUUC-Cja-019831	Callithrix jacchus	94.51	0.00e+00	977.00
IUUC-Cfa-020941	Canis familiaris	94.51	0.00e+00	977.00
IUUC-Cpo-021730	Cavia porcellus	95.05	0.00e+00	979.00
IUUC-Csa-023247	Chlorocebus sabaeus	94.32	0.00e+00	976.00
IUUC-Dre-028474	Danio rerio	82.42	0.00e+00	915.00
IUUC-Dno-029411	Dasypus novemcinctus	93.41	0.00e+00	968.00
IUUC-Dor-030576	Dipodomys ordii	94.69	0.00e+00	977.00
IUUC-Ete-032327	Echinops telfairi	91.76	0.00e+00	945.00
IUUC-Eca-033477	Equus caballus	94.69	0.00e+00	976.00
IUUC-Fca-035546	Felis catus	94.69	0.00e+00	977.00
IUUC-Fal-037370	Ficedula albicollis	90.66	0.00e+00	946.00
IUUC-Gmo-038961	Gadus morhua	79.89	0.00e+00	838.00
IUUC-Gga-041049	Gallus gallus	90.48	0.00e+00	944.00
IUUC-Gac-042003	Gasterosteus aculeatus	77.08	0.00e+00	840.00
IUUC-Ggo-044451	Gorilla gorilla	94.32	0.00e+00	976.00
IUUC-Hsa-045874	Homo sapiens	94.32	0.00e+00	976.00
IUUC-Itr-048357	Ictidomys tridecemlineatus	94.87	0.00e+00	979.00
IUUC-Lch-049603	Latimeria chalumnae	89.47	5.00e-112	396.00
IUUC-Loc-052300	Lepisosteus oculatus	87.00	0.00e+00	949.00
IUUC-Laf-054459	Loxodonta africana	93.41	0.00e+00	968.00
IUUC-Mcc-054846	Macaca mulatta	94.32	0.00e+00	976.00
IUUC-Meu-056797	Macropus eugenii	97.58	6.00e-105	374.00
IUUC-Mga-059446	Meleagris gallopavo	90.66	0.00e+00	946.00
IUUC-Mmr-061125	Microcebus murinus	94.14	0.00e+00	974.00
IUUC-Mdo-062947	Monodelphis domestica	89.96	0.00e+00	917.00
IUUC-Mmu-063708	Mus musculus	94.51	0.00e+00	977.00
IUUC-Mpu-066447	Mustela putorius furo	94.51	0.00e+00	978.00
IUUC-Nle-069918	Nomascus leucogenys	94.32	0.00e+00	976.00
IUUC-Ont-071446	Oreochromis niloticus	80.67	0.00e+00	850.00
IUUC-Oan-072872	Ornithorhynchus anatinus	85.71	0.00e+00	938.00
IUUC-Ocu-073969	Oryctolagus cuniculus	92.87	0.00e+00	794.00
IUUC-Ola-087557	Oryzias latipes	79.39	9.00e-144	502.00
IUUC-Oga-088567	Otolemur garnettii	94.32	0.00e+00	976.00
IUUC-Oar-089882	Ovis aries	94.14	0.00e+00	974.00
IUUC-Ptr-091229	Pan troglodytes	94.32	0.00e+00	977.00
IUUC-Pan-091977	Papio anubis	94.32	0.00e+00	976.00
IUUC-Psi-093496	Pelodiscus sinensis	89.93	2.00e-131	462.00
IUUC-Pfo-096759	Poecilia formosa	79.17	0.00e+00	843.00
IUUC-Pab-098480	Pongo abelii	94.32	0.00e+00	976.00
IUUC-Rno-105500	Rattus norvegicus	94.51	0.00e+00	977.00
IUUC-Sha-106521	Sarcophilus harrisii	89.96	0.00e+00	917.00
IUUC-Ssc-116372	Sus scrofa	94.69	0.00e+00	977.00
IUUC-Tgu-116481	Taeniopygia guttata	90.66	0.00e+00	946.00
IUUC-Tru-118542	Takifugu rubripes	77.44	0.00e+00	833.00
IUUC-Tsy-118848	Tarsius syrichta	87.92	8.00e-102	364.00
IUUC-Tni-119989	Tetraodon nigroviridis	78.60	0.00e+00	808.00
IUUC-Tbe-127485	Tupaia belangeri	94.69	0.00e+00	979.00
IUUC-Ttr-129214	Tursiops truncatus	93.96	0.00e+00	970.00
IUUC-Vpa-130261	Vicugna pacos	94.31	0.00e+00	972.00
IUUC-Xtr-132092	Xenopus tropicalis	86.43	0.00e+00	882.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence