iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000003311.3	ENSMMUT00000068583.1	ENSMMUP00000059134.1
ENSMMUG00000003311.3	ENSMMUT00000004682.3	ENSMMUP00000004415.2
ENSMMUG00000003311.3	ENSMMUT00000070097.1	ENSMMUP00000056031.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-16	61.4	124	160

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H d v+ ++  s+ t  vsGs D  ikvWDl ++v+l
   Q: 124  HDDIVSTVCVlSSgTQAVSGSKDFCIKVWDLAQQVVL 160
           89999999977555*****************999876 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MRKETPPPLV PPAAREWNLP PNAPACMERQ LEAARYRSDG ALLLGASSLS GRCWAGSLWL 60
FKDPCAAPNE GFCSAGVQTE AGVADLTWVG ERGILVASDS GAVELWELDE NETLIVSKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGGCGACA GCCGGAAAGC AGGATGGAGC CGCAGAAGCA ATTCTCGCGA GAAGTAGACT 60
TGCCGTAGCC TCGGGAGAGG GGCGGAGGCT CAGAGGCACA CCACGTGGGG TTTGCTATCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

KEGG

mcc:677686

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	92.13	5.00e-180	623.00
IUUC-Apl-003921	Anas platyrhynchos	63.68	8.00e-67	246.00
IUUC-Aca-004870	Anolis carolinensis	70.97	2.00e-120	424.00
IUUC-Ame-011872	Astyanax mexicanus	46.67	1.00e-37	149.00
IUUC-Bta-013325	Bos taurus	93.27	0.00e+00	633.00
IUUC-Cja-019059	Callithrix jacchus	98.25	0.00e+00	655.00
IUUC-Cfa-021036	Canis familiaris	92.10	2.00e-158	551.00
IUUC-Cpo-022369	Cavia porcellus	91.52	1.00e-179	621.00
IUUC-Csa-023585	Chlorocebus sabaeus	100.00	0.00e+00	670.00
IUUC-Cho-024470	Choloepus hoffmanni	83.82	8.00e-116	409.00
IUUC-Dno-029867	Dasypus novemcinctus	89.47	2.00e-178	618.00
IUUC-Dor-030834	Dipodomys ordii	65.31	3.00e-115	407.00
IUUC-Ete-032245	Echinops telfairi	83.85	5.00e-141	493.00
IUUC-Eca-033360	Equus caballus	92.11	8.00e-175	605.00
IUUC-Eeu-035353	Erinaceus europaeus	90.35	2.00e-177	615.00
IUUC-Fca-036277	Felis catus	93.86	0.00e+00	634.00
IUUC-Fal-037383	Ficedula albicollis	67.44	2.00e-102	365.00
IUUC-Gmo-038575	Gadus morhua	54.65	6.00e-100	357.00
IUUC-Gga-040658	Gallus gallus	70.25	2.00e-129	455.00
IUUC-Gac-041463	Gasterosteus aculeatus	52.04	9.00e-85	306.00
IUUC-Ggo-045120	Gorilla gorilla	97.95	0.00e+00	657.00
IUUC-Hsa-046247	Homo sapiens	98.25	0.00e+00	659.00
IUUC-Itr-048292	Ictidomys tridecemlineatus	95.32	0.00e+00	630.00
IUUC-Lch-049741	Latimeria chalumnae	65.51	2.00e-112	398.00
IUUC-Loc-052695	Lepisosteus oculatus	59.58	7.00e-107	380.00
IUUC-Laf-054535	Loxodonta africana	89.66	6.00e-177	613.00
IUUC-Meu-056053	Macropus eugenii	76.09	2.00e-138	484.00
IUUC-Mga-059672	Meleagris gallopavo	65.46	6.00e-72	263.00
IUUC-Mmr-060963	Microcebus murinus	94.44	0.00e+00	642.00
IUUC-Mdo-062694	Monodelphis domestica	73.47	1.00e-132	465.00
IUUC-Mmu-064031	Mus musculus	90.35	4.00e-177	613.00
IUUC-Mpu-066408	Mustela putorius furo	93.27	0.00e+00	633.00
IUUC-Mlu-068184	Myotis lucifugus	90.67	9.00e-177	612.00
IUUC-Nle-069251	Nomascus leucogenys	99.12	0.00e+00	664.00
IUUC-Opr-071156	Ochotona princeps	84.80	1.00e-164	572.00
IUUC-Ont-072683	Oreochromis niloticus	57.32	3.00e-97	348.00
IUUC-Oan-073042	Ornithorhynchus anatinus	75.87	6.00e-127	446.00
IUUC-Ocu-074843	Oryctolagus cuniculus	94.17	4.00e-178	616.00
IUUC-Ola-086929	Oryzias latipes	53.54	5.00e-89	320.00
IUUC-Oga-088237	Otolemur garnettii	93.27	0.00e+00	631.00
IUUC-Oar-089312	Ovis aries	93.04	5.00e-167	579.00
IUUC-Ptr-091625	Pan troglodytes	98.25	0.00e+00	658.00
IUUC-Pan-091902	Papio anubis	95.06	0.00e+00	630.00
IUUC-Psi-094035	Pelodiscus sinensis	71.53	3.00e-126	444.00
IUUC-Pma-094565	Petromyzon marinus	62.92	2.00e-56	211.00
IUUC-Pfo-097070	Poecilia formosa	54.49	3.00e-92	331.00
IUUC-Pab-098007	Pongo abelii	98.83	0.00e+00	662.00
IUUC-Pca-100513	Procavia capensis	74.44	4.00e-104	370.00
IUUC-Pva-102821	Pteropus vampyrus	87.72	3.00e-167	580.00
IUUC-Rno-105836	Rattus norvegicus	89.66	6.00e-179	619.00
IUUC-Sha-106847	Sarcophilus harrisii	70.61	6.00e-89	320.00
IUUC-Sar-113451	Sorex araneus	84.84	9.00e-168	582.00
IUUC-Ssc-115978	Sus scrofa	92.11	1.00e-175	608.00
IUUC-Tgu-116745	Taeniopygia guttata	69.74	2.00e-95	341.00
IUUC-Tru-117945	Takifugu rubripes	53.11	2.00e-81	295.00
IUUC-Tsy-119059	Tarsius syrichta	90.40	5.00e-92	329.00
IUUC-Tni-120414	Tetraodon nigroviridis	54.29	7.00e-94	337.00
IUUC-Tbe-127559	Tupaia belangeri	95.91	0.00e+00	649.00
IUUC-Ttr-128505	Tursiops truncatus	90.94	3.00e-176	610.00
IUUC-Vpa-130350	Vicugna pacos	94.51	4.00e-101	360.00
IUUC-Xtr-132939	Xenopus tropicalis	62.15	4.00e-114	404.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence