iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Meu-056342

Ensembl Protein ID

ENSMEUP00000014314.1

UniProt Accession

C0KHA0; C0KHA0_MACEU

Genbank Protein ID

ACM88651.1

Protein Name

Breast and ovarian cancer susceptibility 1

Genbank Nucleotide ID

FJ603179

Gene Name

BRCA1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMEUG00000015661.1	ENSMEUT00000015721.1	ENSMEUP00000014314.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	38.29	3.00e-126	452.00	IUUC-Hsa-046086

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Macropus eugenii

Protein Sequence
(Fasta)

MDLSTVNIEE VKKVIIGMQK ILECPICLEV IKEPVSTSCD HICXXXXXXX XXXXXXXXXX 60
XXXXXXXXXX SLRESTRFNQ LVEGLLKTIR AFELDTGFQF SDSQDFSKWK KRTAEPLKKE 120

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Nucleotide Sequence
(Fasta)

ATGGATTTAT CTACAGTCAA TATTGAAGAA GTAAAGAAGG TCATCATTGG CATGCAGAAA 60
ATCTTAGAAT GTCCTATCTG GTAAGTTTGT AGGCCAGTCA TCATTTATTT GTGACCCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Interpro

IPR011364--BRCA1
IPR031099--BRCA1-associated
IPR025994--BRCA1_serine_dom

Pfam

PF12820--BRCT_assoc

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002388	Ailuropoda melanoleuca	38.31	5.00e-136	479.00
IUUC-Apl-003252	Anas platyrhynchos	51.23	2.00e-43	172.00
IUUC-Aca-004526	Anolis carolinensis	51.25	6.00e-42	165.00
IUUC-Ame-011720	Astyanax mexicanus	39.24	1.00e-23	105.00
IUUC-Bta-013433	Bos taurus	37.02	2.00e-124	440.00
IUUC-Cja-019149	Callithrix jacchus	38.53	8.00e-124	438.00
IUUC-Cfa-020322	Canis familiaris	37.12	5.00e-129	456.00
IUUC-Cpo-021583	Cavia porcellus	51.23	6.00e-43	170.00
IUUC-Csa-024227	Chlorocebus sabaeus	56.46	9.00e-41	161.00
IUUC-Cho-024530	Choloepus hoffmanni	42.36	7.00e-60	226.00
IUUC-Dno-029247	Dasypus novemcinctus	40.57	1.00e-131	464.00
IUUC-Ete-032472	Echinops telfairi	36.45	3.00e-78	287.00
IUUC-Eca-033446	Equus caballus	39.70	3.00e-142	500.00
IUUC-Eeu-034858	Erinaceus europaeus	37.80	9.00e-52	199.00
IUUC-Fca-035991	Felis catus	38.10	4.00e-130	459.00
IUUC-Fal-036803	Ficedula albicollis	49.08	2.00e-42	168.00
IUUC-Gmo-038782	Gadus morhua	37.89	1.00e-21	98.60
IUUC-Gga-040969	Gallus gallus	50.61	2.00e-43	171.00
IUUC-Gac-042296	Gasterosteus aculeatus	40.00	2.00e-21	98.60
IUUC-Ggo-044740	Gorilla gorilla	39.03	1.00e-126	448.00
IUUC-Hsa-046086	Homo sapiens	38.29	1.00e-125	444.00
IUUC-Itr-048512	Ictidomys tridecemlineatus	37.85	2.00e-127	450.00
IUUC-Lch-049789	Latimeria chalumnae	46.39	2.00e-37	152.00
IUUC-Loc-051952	Lepisosteus oculatus	46.01	5.00e-35	143.00
IUUC-Lma-053020	Leptosphaeria maculans	34.88	7.60e-01	26.20
IUUC-Laf-053648	Loxodonta africana	39.48	9.00e-129	455.00
IUUC-Mcc-055210	Macaca mulatta	38.29	2.00e-133	470.00
IUUC-Mga-060163	Meleagris gallopavo	49.38	4.00e-42	167.00
IUUC-Mmr-061402	Microcebus murinus	58.44	2.00e-11	63.90
IUUC-Mdo-062209	Monodelphis domestica	66.46	0.00e+00	1080.00
IUUC-Mmu-064003	Mus musculus	33.95	3.00e-76	281.00
IUUC-Mpu-065825	Mustela putorius furo	58.18	4.00e-52	199.00
IUUC-Mlu-068176	Myotis lucifugus	39.12	9.00e-131	461.00
IUUC-Nle-069178	Nomascus leucogenys	39.39	1.00e-132	468.00
IUUC-Opr-070574	Ochotona princeps	33.97	1.00e-97	351.00
IUUC-Ont-072380	Oreochromis niloticus	41.61	2.00e-25	111.00
IUUC-Oan-073243	Ornithorhynchus anatinus	44.71	4.00e-13	66.60
IUUC-Ocu-074424	Oryctolagus cuniculus	37.39	3.00e-112	400.00
IUUC-Ola-086863	Oryzias latipes	41.72	2.00e-23	104.00
IUUC-Oar-089938	Ovis aries	36.92	1.00e-125	444.00
IUUC-Ptr-090960	Pan troglodytes	38.90	2.00e-133	470.00
IUUC-Pan-092609	Papio anubis	39.42	1.00e-136	481.00
IUUC-Psi-093889	Pelodiscus sinensis	30.89	1.00e-32	135.00
IUUC-Pfo-096328	Poecilia formosa	42.94	2.00e-26	114.00
IUUC-Pab-097982	Pongo abelii	39.60	1.00e-131	464.00
IUUC-Pca-100698	Procavia capensis	54.17	6.00e-49	189.00
IUUC-Pva-102631	Pteropus vampyrus	39.96	1.00e-63	239.00
IUUC-Rno-105879	Rattus norvegicus	32.67	9.00e-74	272.00
IUUC-Sha-106701	Sarcophilus harrisii	62.95	0.00e+00	991.00
IUUC-Sar-113047	Sorex araneus	37.72	2.00e-84	307.00
IUUC-Ssc-115846	Sus scrofa	38.63	3.00e-129	456.00
IUUC-Tgu-116785	Taeniopygia guttata	49.08	5.00e-42	167.00
IUUC-Tru-117895	Takifugu rubripes	39.75	2.00e-24	108.00
IUUC-Tsy-118885	Tarsius syrichta	40.59	1.00e-53	205.00
IUUC-Tni-119654	Tetraodon nigroviridis	40.37	2.00e-23	104.00
IUUC-Tbe-127421	Tupaia belangeri	37.59	1.00e-49	192.00
IUUC-Ttr-128685	Tursiops truncatus	38.70	1.00e-131	464.00
IUUC-Vpa-130216	Vicugna pacos	41.15	9.00e-98	352.00
IUUC-Xtr-132398	Xenopus tropicalis	42.94	7.00e-27	116.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence