iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oin-079997

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin carboxyl-terminal hydrolase 26; Deubiquitinating enzyme 26; Ubiquitin thioesterase 26; Ubiquitin-specific-processing protease 26

Genbank Nucleotide ID

CM000128

Gene Name

UBP26; OsI_010107

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
BGIOSGA012029	BGIOSGA012029-TA	BGIOSGA012029-PA

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.90e-68	230.8	107	445

Active Site

Position(s)	Description	Evidence
115	Nucleophile	ECO:0000255\|PROSITE-ProRule:PRU10092, ECO:0000255\|PROSITE-ProRule:PRU10093}
359	Proton acceptor	ECO:0000255\|PROSITE-ProRule:PRU10092, ECO:0000255\|PROSITE-ProRule:PRU10093}

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqE 94
           Gl+Nlg+tCY NS+LQcL++ +++r  +++ ++  l+         ++l++l++lf++l +sk   ++   ++k+l+      ++  qqD++E
   Q: 107  GLTNLGATCYANSILQCLYMNTSFRLGIFSLEPDILKM-------HPVLDQLARLFAQLHSSKMAFIDSAPFIKTLEL-----DNGVQQDSHE 187
           9*****************************88887765.......48*****************************95.....5567****** PP
   S: 95   flaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs...sreepfldlslpvpgkeetkk 184
           fl+ +l+ le +l                       + +k    ++++++lF+g++++ ++c +c++ s   s+ e+f++l+l+++g +    
   Q: 188  FLTLFLSLLEGSL-----------------------SHSKVPGARTIVQHLFRGSVSHVTRCSSCGRDSeasSKMEDFYELELNIKGLN---- 253
           *************.......................457889999********************988766699***************.... PP
   S: 185  eslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkk 277
            +l+++L+++ ++e l+gen+y+ce+c+k+++a++ +kl++lP+v  ++LkR+ f  ++  ++ki++ ++fp +Ld+ + +++p++    +++
   Q: 254  -NLEQSLDDYLSTEALDGENQYFCESCQKRVDATRCIKLRSLPPVVNFQLKRYVFLPKTTTKKKISSAFSFPGQLDMGKRLSNPSS----SYT 341
           .9*******************************************************************************99886....69* PP
   S: 278  YeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetg......................................... 327
           Y L+a+++H+G  ++sGHYva+vk+e+++ W++fdD++V+++  + + e+ g                                         
   Q: 342  YGLSAILIHKGsAANSGHYVAHVKDESNGqWWEFDDEHVSKLGLHPFGEKPGkssnktdqkpqgsstadsvtnddnnscheaaftstmeemfs 434
           *************************65555***********9988888866688889999********************************* PP
   S: 328  .staYvlfYkr 337
            ++aY+l+Ykr
   Q: 435  sTDAYMLMYKR 445
           *********97 PP

Organism

Oryza indica

Functional Description
(View)

Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Deubiquitinates H2BK143ub1 of histone H2B (By similarity).

Protein Sequence
(Fasta)

MSRPNTRNKS KRPRADDCES PSAVFKKIHS TGAITKGDIK QLYMVWKPVC HGCHGNSKDS 60
PNCFCGLIPA ANGVRKSGLW QRTNEIIRAL GPNPSTDLRD STETPAGLTN LGATCYANSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCAGGC CAAACACACG AAATAAGAGC AAGAGGCCGC GGGCTGATGA CTGCGAGAGC 60
CCGTCTGCTG TTTTCAAGTA TGTCTGCATT GCCTTGTTGC CTTGGCCAAA GCTGTGGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0539--Nucleus
KW-0645--Protease
KW-1185--Reference proteome
KW-0677--Repeat
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR033841--USP48
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005730--C:nucleolus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0048316--P:seed development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000130	Aegilops tauschii	79.20	0.00e+00	1655.00
IUUC-Aml-001357	Ailuropoda melanoleuca	31.83	1.00e-86	313.00
IUUC-Atr-002976	Amborella trichopoda	57.20	0.00e+00	1175.00
IUUC-Apl-003773	Anas platyrhynchos	34.51	2.00e-87	317.00
IUUC-Aca-004466	Anolis carolinensis	36.06	1.00e-88	319.00
IUUC-Aly-006249	Arabidopsis lyrata	54.62	0.00e+00	1133.00
IUUC-Ath-006700	Arabidopsis thaliana	55.82	0.00e+00	1176.00
IUUC-Ame-011554	Astyanax mexicanus	33.65	3.00e-88	319.00
IUUC-Bta-012573	Bos taurus	33.95	6.00e-89	321.00
IUUC-Bdi-014149	Brachypodium distachyon	80.72	0.00e+00	1718.00
IUUC-Bol-016289	Brassica oleracea	55.28	0.00e+00	1128.00
IUUC-Bra-017494	Brassica rapa	54.00	0.00e+00	1093.00
IUUC-Cja-019991	Callithrix jacchus	32.03	9.00e-89	321.00
IUUC-Cfa-020294	Canis familiaris	32.19	2.00e-89	323.00
IUUC-Cpo-021706	Cavia porcellus	31.77	1.00e-84	307.00
IUUC-Cre-022636	Chlamydomonas reinhardtii	43.88	7.00e-69	256.00
IUUC-Csa-023931	Chlorocebus sabaeus	32.35	4.00e-90	325.00
IUUC-Cho-024566	Choloepus hoffmanni	27.74	2.00e-31	130.00
IUUC-Cin-025307	Ciona intestinalis	37.05	4.00e-42	164.00
IUUC-Csv-026006	Ciona savignyi	26.96	5.00e-64	239.00
IUUC-Cne-027065	Cryptococcus neoformans	27.39	5.00e-56	212.00
IUUC-Dre-027624	Danio rerio	33.28	3.00e-89	322.00
IUUC-Dno-029633	Dasypus novemcinctus	33.21	1.00e-79	290.00
IUUC-Dor-030809	Dipodomys ordii	37.78	5.00e-52	199.00
IUUC-Dme-032102	Drosophila melanogaster	28.06	4.00e-34	141.00
IUUC-Ete-032818	Echinops telfairi	31.85	2.00e-73	270.00
IUUC-Eca-033692	Equus caballus	32.61	7.00e-89	321.00
IUUC-Eeu-035185	Erinaceus europaeus	32.65	1.00e-35	144.00
IUUC-Fca-035676	Felis catus	32.61	5.00e-90	325.00
IUUC-Fal-036913	Ficedula albicollis	34.80	2.00e-88	320.00
IUUC-Gmo-038532	Gadus morhua	30.74	1.00e-85	310.00
IUUC-Gga-041041	Gallus gallus	33.67	1.00e-87	317.00
IUUC-Gac-042570	Gasterosteus aculeatus	34.34	3.00e-87	316.00
IUUC-Gma-043910	Glycine max	57.53	0.00e+00	1172.00
IUUC-Ggo-045367	Gorilla gorilla	32.40	4.00e-82	299.00
IUUC-Hsa-046019	Homo sapiens	32.19	2.00e-89	323.00
IUUC-Hvu-047303	Hordeum vulgare	81.00	0.00e+00	828.00
IUUC-Itr-048319	Ictidomys tridecemlineatus	32.04	7.00e-89	321.00
IUUC-Lch-049989	Latimeria chalumnae	25.89	2.00e-91	330.00
IUUC-Lpe-051612	Leersia perrieri	91.21	0.00e+00	1929.00
IUUC-Loc-052756	Lepisosteus oculatus	34.64	8.00e-88	318.00
IUUC-Laf-054043	Loxodonta africana	31.88	2.00e-88	320.00
IUUC-Mcc-054986	Macaca mulatta	32.23	1.00e-89	323.00
IUUC-Meu-056228	Macropus eugenii	39.60	7.00e-64	238.00
IUUC-Mtr-058762	Medicago truncatula	58.20	0.00e+00	1185.00
IUUC-Mga-059896	Meleagris gallopavo	34.32	7.00e-86	311.00
IUUC-Mvi-060269	Microbotryum violaceum	39.55	1.00e-56	215.00
IUUC-Mmr-060887	Microcebus murinus	32.04	4.00e-88	319.00
IUUC-Mdo-062506	Monodelphis domestica	33.39	2.00e-88	320.00
IUUC-Mmu-063642	Mus musculus	31.92	2.00e-88	320.00
IUUC-Mac-064896	Musa acuminata	67.19	0.00e+00	1405.00
IUUC-Mpu-066194	Mustela putorius furo	32.76	8.00e-89	321.00
IUUC-Mlu-067233	Myotis lucifugus	31.69	1.00e-86	314.00
IUUC-Nle-069052	Nomascus leucogenys	32.23	1.00e-89	323.00
IUUC-Opr-070890	Ochotona princeps	31.52	1.00e-83	304.00
IUUC-Ont-071450	Oreochromis niloticus	31.31	5.00e-90	325.00
IUUC-Ocu-073796	Oryctolagus cuniculus	33.66	2.00e-79	290.00
IUUC-Oba-075563	Oryza barthii	99.91	0.00e+00	2144.00
IUUC-Obr-076394	Oryza brachyantha	91.87	0.00e+00	1968.00
IUUC-Ogl-077339	Oryza glaberrima	99.68	4.00e-176	609.00
IUUC-Ogu-079007	Oryza glumaepatula	98.52	0.00e+00	2103.00
IUUC-Olo-080364	Oryza longistaminata	97.91	0.00e+00	2130.00
IUUC-Ome-081165	Oryza meridionalis	97.59	0.00e+00	2080.00
IUUC-Oni-083026	Oryza nivara	99.91	0.00e+00	2146.00
IUUC-Opu-083284	Oryza punctata	94.45	0.00e+00	2013.00
IUUC-Oru-084797	Oryza rufipogon	99.91	0.00e+00	2146.00
IUUC-Osa-086221	Oryza sativa	99.68	4.00e-176	609.00
IUUC-Ola-086568	Oryzias latipes	27.60	2.00e-92	333.00
IUUC-Oga-088687	Otolemur garnettii	32.08	1.00e-88	320.00
IUUC-Oar-090345	Ovis aries	33.92	1.00e-86	313.00
IUUC-Ptr-090734	Pan troglodytes	32.35	4.00e-90	325.00
IUUC-Pan-091704	Papio anubis	31.56	7.00e-86	311.00
IUUC-Psi-092937	Pelodiscus sinensis	29.38	1.00e-77	284.00
IUUC-Ppa-095808	Physcomitrella patens	45.65	0.00e+00	859.00
IUUC-Pab-098129	Pongo abelii	32.35	4.00e-90	325.00
IUUC-Pop-099738	Populus trichocarpa	58.47	0.00e+00	1185.00
IUUC-Pca-100647	Procavia capensis	37.85	2.00e-52	200.00
IUUC-Ppe-102091	Prunus persica	60.33	0.00e+00	1259.00
IUUC-Pva-102719	Pteropus vampyrus	31.88	2.00e-87	316.00
IUUC-Rno-105363	Rattus norvegicus	32.04	8.00e-89	321.00
IUUC-Sha-107620	Sarcophilus harrisii	34.38	3.00e-86	313.00
IUUC-Smo-109487	Selaginella moellendorffii	45.54	0.00e+00	830.00
IUUC-Sit-110683	Setaria italica	81.01	0.00e+00	1651.00
IUUC-Sly-111377	Solanum lycopersicum	58.23	0.00e+00	1163.00
IUUC-Stu-111969	Solanum tuberosum	60.36	0.00e+00	670.00
IUUC-Sar-113099	Sorex araneus	34.25	6.00e-80	291.00
IUUC-Sbi-113833	Sorghum bicolor	87.42	1.00e-140	491.00
IUUC-Tgu-117519	Taeniopygia guttata	33.04	5.00e-78	285.00
IUUC-Tru-117651	Takifugu rubripes	30.34	3.00e-87	316.00
IUUC-Tsy-119201	Tarsius syrichta	30.53	5.00e-74	272.00
IUUC-Tni-120840	Tetraodon nigroviridis	30.85	8.00e-92	331.00
IUUC-Tca-121674	Theobroma cacao	60.44	0.00e+00	1271.00
IUUC-Tae-125814	Triticum aestivum	80.54	0.00e+00	1670.00
IUUC-Tur-126599	Triticum urartu	79.29	0.00e+00	1653.00
IUUC-Tbe-127782	Tupaia belangeri	35.34	2.00e-33	137.00
IUUC-Ttr-128312	Tursiops truncatus	31.42	5.00e-85	308.00
IUUC-Vpa-130348	Vicugna pacos	31.83	2.00e-83	303.00
IUUC-Vvi-131353	Vitis vinifera	59.86	0.00e+00	1279.00
IUUC-Xtr-132172	Xenopus tropicalis	30.38	5.00e-59	222.00
IUUC-Xma-133263	Xiphophorus maculatus	30.57	3.00e-80	293.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence