iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003708

Ensembl Protein ID

ENSAPLP00000013317.1

UniProt Accession

U3J1E0; U3J1E0_ANAPL

Genbank Protein ID

ENSAPLP00000013317

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01106540

Gene Name

TBL1XR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000013445.1	ENSAPLT00000014067.1	ENSAPLP00000013317.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-53	176.6	326	364
UBD/Beta-Prp	3.90e-66	223.0	290	492

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHt++v+++++ ++ +ll+s+sdD t+k+W+++++ +++
   Q: 326  GHTNEVNAIKWdPTgNLLASCSDDMTLKIWSMKQDSCVH 364
           8***********778********************9986 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsls 101
             +v++ ++++ +a+ s+d +i v ++ +   +++++gh++ev+a+k++p+g++l+++s+D+t+k+w++++ +cvh l++h++++++++
   Q: 290  ALDVDW-QSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDSCVHDLQAHNKEIYTIK 377
           444555.6667777777777777777777777777777777777777777777777777777777777777777777777777777777 PP
   S: 102  fsp........sg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           +sp        +    l+s+s d+t+r+wd++ g c++ tl++h++ v +v+++pdg++l+sGs D++v +W+ +tg l++  +g  t+
   Q: 378  WSPtgpgtnnpNAnLMLASASFDSTVRLWDVDRGICIH-TLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG--TG 463
           77755555443222457777777777777777777777.7777777777777777777777777777777777777777777776..77 PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlq 210
            +  + ++  g  + + + dg+v + dl+
   Q: 464  GIFEVCWNAAGDKVGASASDGSVCVLDLR 492
           77777777777777777777777666665 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

FSHSAFTFGI ESHISQSNIN GALVPPAALI SIIQKGLQYV EAEVSINEDG TLFDGRPIES 60
LSLIDAVMPD VVQTRQQAYR DKLAQQQAAA AAAAAATNQQ GSAKNGENTA NGEENGAHTI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCATCACCC TTTTGTGGCA AGAGACACCT GAAAGGAAAA CTTCCTCATA TCAATGCACT 60
GCCAATGGTA AGTACCTTCT TAACTGACTA ATGGTGGTGT GGTTCCTTCC TGCAAATGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0005876--C:spindle microtubule
GO:0017053--C:transcriptional repressor complex
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0060613--P:fat pad development
GO:0016042--P:lipid catabolic process
GO:0035264--P:multicellular organism growth
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0030814--P:regulation of cAMP metabolic process
GO:0090207--P:regulation of triglyceride metabolic process
GO:0002021--P:response to dietary excess
GO:0050872--P:white fat cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000916	Aegilops tauschii	60.71	4.00e-55	206.00
IUUC-Aml-001717	Ailuropoda melanoleuca	95.14	0.00e+00	913.00
IUUC-Atr-002514	Amborella trichopoda	65.38	6.00e-145	507.00
IUUC-Aca-004611	Anolis carolinensis	98.99	0.00e+00	925.00
IUUC-Aly-005622	Arabidopsis lyrata	58.40	6.00e-120	424.00
IUUC-Ath-007137	Arabidopsis thaliana	59.50	2.00e-121	429.00
IUUC-Ago-007869	Ashbya gossypii	27.98	6.00e-32	131.00
IUUC-Ame-011601	Astyanax mexicanus	89.45	0.00e+00	865.00
IUUC-Bta-012418	Bos taurus	98.99	0.00e+00	946.00
IUUC-Bdi-014315	Brachypodium distachyon	60.42	1.00e-134	473.00
IUUC-Bol-016277	Brassica oleracea	56.99	2.00e-126	445.00
IUUC-Bra-016944	Brassica rapa	60.28	8.00e-126	443.00
IUUC-Cja-018832	Callithrix jacchus	98.79	0.00e+00	916.00
IUUC-Cfa-020029	Canis familiaris	94.94	0.00e+00	912.00
IUUC-Cpo-022080	Cavia porcellus	93.93	0.00e+00	884.00
IUUC-Csa-024075	Chlorocebus sabaeus	95.55	0.00e+00	912.00
IUUC-Dre-028075	Danio rerio	96.15	0.00e+00	894.00
IUUC-Dno-029196	Dasypus novemcinctus	99.39	0.00e+00	926.00
IUUC-Dor-030732	Dipodomys ordii	98.90	0.00e+00	729.00
IUUC-Eeu-034952	Erinaceus europaeus	88.16	0.00e+00	783.00
IUUC-Fca-035734	Felis catus	98.79	0.00e+00	924.00
IUUC-Fal-037185	Ficedula albicollis	99.59	0.00e+00	929.00
IUUC-Gmo-038870	Gadus morhua	90.06	0.00e+00	891.00
IUUC-Gga-041161	Gallus gallus	99.80	0.00e+00	932.00
IUUC-Gac-041844	Gasterosteus aculeatus	91.92	0.00e+00	916.00
IUUC-Ggo-044882	Gorilla gorilla	95.55	0.00e+00	912.00
IUUC-Hsa-046488	Homo sapiens	95.55	0.00e+00	912.00
IUUC-Itr-047958	Ictidomys tridecemlineatus	99.45	0.00e+00	736.00
IUUC-Lch-050672	Latimeria chalumnae	95.76	0.00e+00	930.00
IUUC-Lpe-051084	Leersia perrieri	62.64	2.00e-136	478.00
IUUC-Loc-052030	Lepisosteus oculatus	94.98	0.00e+00	922.00
IUUC-Laf-054280	Loxodonta africana	98.58	0.00e+00	946.00
IUUC-Mcc-055203	Macaca mulatta	95.55	0.00e+00	912.00
IUUC-Meu-056563	Macropus eugenii	98.74	3.00e-135	474.00
IUUC-Mtr-058624	Medicago truncatula	60.44	1.00e-128	452.00
IUUC-Mga-059660	Meleagris gallopavo	99.80	0.00e+00	932.00
IUUC-Mmr-060925	Microcebus murinus	98.38	0.00e+00	912.00
IUUC-Mdo-062078	Monodelphis domestica	98.59	0.00e+00	922.00
IUUC-Mmu-063603	Mus musculus	98.79	0.00e+00	921.00
IUUC-Mac-065508	Musa acuminata	61.80	3.00e-93	335.00
IUUC-Mpu-066741	Mustela putorius furo	94.94	0.00e+00	912.00
IUUC-Mlu-068152	Myotis lucifugus	99.19	0.00e+00	919.00
IUUC-Nle-069229	Nomascus leucogenys	95.55	0.00e+00	912.00
IUUC-Opr-070277	Ochotona princeps	87.89	0.00e+00	776.00
IUUC-Ont-072623	Oreochromis niloticus	91.92	0.00e+00	916.00
IUUC-Ocu-074280	Oryctolagus cuniculus	97.22	0.00e+00	913.00
IUUC-Obr-076718	Oryza brachyantha	62.91	6.00e-137	480.00
IUUC-Olo-080427	Oryza longistaminata	63.32	5.00e-132	464.00
IUUC-Ola-087365	Oryzias latipes	94.95	0.00e+00	912.00
IUUC-Oga-088357	Otolemur garnettii	94.93	0.00e+00	865.00
IUUC-Oar-089214	Ovis aries	99.19	0.00e+00	950.00
IUUC-Ptr-091532	Pan troglodytes	95.55	0.00e+00	912.00
IUUC-Pan-091927	Papio anubis	95.55	0.00e+00	912.00
IUUC-Psi-093941	Pelodiscus sinensis	92.11	0.00e+00	897.00
IUUC-Ppa-095868	Physcomitrella patens	66.57	9.00e-140	489.00
IUUC-Pfo-096158	Poecilia formosa	91.72	0.00e+00	916.00
IUUC-Pab-098705	Pongo abelii	95.55	0.00e+00	912.00
IUUC-Pop-098989	Populus trichocarpa	61.54	7.00e-128	450.00
IUUC-Pca-100256	Procavia capensis	97.96	0.00e+00	902.00
IUUC-Ppe-101572	Prunus persica	63.69	6.00e-128	450.00
IUUC-Pva-102616	Pteropus vampyrus	98.77	0.00e+00	905.00
IUUC-Rno-105411	Rattus norvegicus	98.99	0.00e+00	924.00
IUUC-Sha-106636	Sarcophilus harrisii	98.18	0.00e+00	915.00
IUUC-Smo-109301	Selaginella moellendorffii	63.49	1.00e-142	499.00
IUUC-Sit-110710	Setaria italica	63.71	2.00e-142	498.00
IUUC-Sar-112971	Sorex araneus	86.33	0.00e+00	830.00
IUUC-Sbi-114420	Sorghum bicolor	63.19	3.00e-142	498.00
IUUC-Sre-115175	Sporisorium reilianum	36.84	6.00e-58	218.00
IUUC-Ssc-115695	Sus scrofa	99.39	0.00e+00	926.00
IUUC-Tgu-117009	Taeniopygia guttata	99.79	0.00e+00	914.00
IUUC-Tru-118581	Takifugu rubripes	95.15	0.00e+00	918.00
IUUC-Tsy-119424	Tarsius syrichta	81.11	0.00e+00	692.00
IUUC-Tni-119986	Tetraodon nigroviridis	95.35	0.00e+00	920.00
IUUC-Tca-121739	Theobroma cacao	56.87	7.00e-125	440.00
IUUC-Tae-125368	Triticum aestivum	61.62	9.00e-136	476.00
IUUC-Tur-126856	Triticum urartu	60.61	7.00e-62	231.00
IUUC-Tme-127126	Tuber melanosporum	38.71	1.00e-58	220.00
IUUC-Tbe-127665	Tupaia belangeri	82.52	0.00e+00	786.00
IUUC-Vpa-130768	Vicugna pacos	95.09	0.00e+00	898.00
IUUC-Vvi-131193	Vitis vinifera	60.16	2.00e-128	452.00
IUUC-Xtr-132842	Xenopus tropicalis	92.08	0.00e+00	872.00
IUUC-Xma-134020	Xiphophorus maculatus	91.72	0.00e+00	916.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence