iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001525

Ensembl Protein ID

ENSAMEP00000010651.1

UniProt Accession

G1LUA3; G1LUA3_AILME

Genbank Protein ID

ENSAMEP00000010651

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01096566

Gene Name

NWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000010118.1	ENSAMET00000011111.1	ENSAMEP00000010651.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.40e-24	84.5	909	943
UBD/Beta-Prp	1.90e-57	194.8	1127	1463

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtcla.f.sdtllvsGsdDgtikvWDlrtg 33
           gHt++v+c++ f  +tl +s+s D+t+++WDl +g
   Q: 909  GHTGEVRCVEvFaKGTLALSASKDHTLRLWDLLSG 943
           8********9778669***************9776 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkl.lrslsgheaevtavkfspdgkilvtgseD.rtikvwdlstgkcvhtlkg 92
           +h++ +    f p+++l++tgsrd+ i+vw+++++ + l  l+g  a+++ + +     + +++s+     kvwdl + +  ++ + 
   Q: 1127 EHEDIVETASFGPENNLIITGSRDALIQVWSLSEQGTlLDILEGVGAPTSLLAWGGA--LVASASQQsSSFKVWDLTDVQKPRACTP 1211
           678888889999*******************98877635555777777777777666..7888887778888888888888888888 PP
   S: 93   hedsvlslsfspsgdklv..sGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.. 175
             d+  ++++s +g ++     ++ + + +wd  +g++    l+  +  v+c++v + +nll++G   ++v ++ l + + +     
   Q: 1212 FLDRTGLTAVSHNGGYVYfpKIGDKNKVTIWDSAEGEEQD-ALDTSS-EVRCLEVAQRANLLFTGLVSGVVLVFPLHSRQDVMCIpp 1296
           8888888888887754432234557888889888888888.444443.489999999999999999999999999955555555554 PP
   S: 176  tgghtdsvyslsfdsng................................................kelvsgsldgtvklwdlqtgec 214
            +   ++v++++++                                                    ++++g ++g++ l+++ +++ 
   Q: 1297 PE-ARKAVNCMALSTGEerlaiaydsivlvldispgdpcpvidgptytfytqlpetiasvavladYRVIYGMTNGDLFLYECANSK- 1381
           33.567777777444444555555556666666667777777777777777777778888888879****************9887. PP
   S: 215  vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvav..lsfgdnvlvlgsedskvniwkl 294
           v  l++h ++v ++++s ++++ vsgs++  + +Wdl+  +   +++++ns    v++  +s++dn++++g +d ++ +w++
   Q: 1382 VFPLEAHGSQVACMQVSHQEQLAVSGSEEALLCLWDLQACKWRFQMNYTNSYCRGVQCvcFSMDDNYVYAGLKDRSIIVWSV 1463
           99************************************************88888888335666****************86 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MDAEREALQS TAFPEVQTFC QKHGLMFEVV DLRWGIQNTE ATDHMTTELC LEELDRCRKT 60
SIGPAFVALL GDQYGPCPVP TLIEEKEWEA LRAQLTSRPR DLELVARRFR RDENAVPPTY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGCAG AACGAGAAGC TCTGCAGAGC ACGGCCTTCC CCGAAGTTCA AACCTTCTGC 60
CAAAAGCACG GGCTCATGTT CGAGGTAATA GCTTCCTCCC TGTCTCGGTG TCCCCTGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR027417--P-loop_NTPase
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003467	Anas platyrhynchos	58.80	2.00e-81	295.00
IUUC-Ame-011400	Astyanax mexicanus	36.35	0.00e+00	983.00
IUUC-Bta-013223	Bos taurus	86.23	0.00e+00	2324.00
IUUC-Cel-018404	Caenorhabditis elegans	28.20	3.00e-109	390.00
IUUC-Cja-018773	Callithrix jacchus	80.92	0.00e+00	1524.00
IUUC-Cfa-020334	Canis familiaris	92.75	0.00e+00	2897.00
IUUC-Cpo-022316	Cavia porcellus	67.07	0.00e+00	1948.00
IUUC-Csa-023631	Chlorocebus sabaeus	83.20	0.00e+00	2565.00
IUUC-Cin-025646	Ciona intestinalis	32.59	9.00e-131	461.00
IUUC-Csv-026191	Ciona savignyi	26.20	9.00e-27	114.00
IUUC-Dre-028241	Danio rerio	36.20	0.00e+00	948.00
IUUC-Dno-029990	Dasypus novemcinctus	78.83	0.00e+00	694.00
IUUC-Dor-030869	Dipodomys ordii	62.25	4.00e-180	625.00
IUUC-Ete-033059	Echinops telfairi	82.82	0.00e+00	838.00
IUUC-Eca-033718	Equus caballus	82.27	0.00e+00	2544.00
IUUC-Fca-035748	Felis catus	90.16	0.00e+00	2611.00
IUUC-Gac-041507	Gasterosteus aculeatus	35.68	0.00e+00	748.00
IUUC-Ggo-044551	Gorilla gorilla	80.04	0.00e+00	2449.00
IUUC-Hsa-046787	Homo sapiens	82.46	0.00e+00	2558.00
IUUC-Itr-048104	Ictidomys tridecemlineatus	64.31	0.00e+00	1820.00
IUUC-Lch-049578	Latimeria chalumnae	47.88	0.00e+00	1437.00
IUUC-Loc-052039	Lepisosteus oculatus	40.94	0.00e+00	1224.00
IUUC-Laf-054240	Loxodonta africana	83.78	0.00e+00	2675.00
IUUC-Mcc-054657	Macaca mulatta	75.73	0.00e+00	2215.00
IUUC-Meu-056591	Macropus eugenii	63.54	0.00e+00	1152.00
IUUC-Mmr-061577	Microcebus murinus	80.18	0.00e+00	2467.00
IUUC-Mdo-062895	Monodelphis domestica	62.61	0.00e+00	1803.00
IUUC-Mmu-063866	Mus musculus	77.57	0.00e+00	2390.00
IUUC-Mpu-066510	Mustela putorius furo	92.14	0.00e+00	2917.00
IUUC-Mlu-067855	Myotis lucifugus	86.26	0.00e+00	2623.00
IUUC-Nle-069557	Nomascus leucogenys	78.19	0.00e+00	2346.00
IUUC-Opr-071196	Ochotona princeps	64.34	0.00e+00	643.00
IUUC-Ont-072070	Oreochromis niloticus	35.92	0.00e+00	820.00
IUUC-Oan-073437	Ornithorhynchus anatinus	58.68	0.00e+00	1291.00
IUUC-Ocu-074941	Oryctolagus cuniculus	81.82	8.00e-52	196.00
IUUC-Ola-086624	Oryzias latipes	33.56	0.00e+00	691.00
IUUC-Oga-088313	Otolemur garnettii	83.95	0.00e+00	2361.00
IUUC-Oar-090123	Ovis aries	86.45	0.00e+00	2688.00
IUUC-Ptr-090552	Pan troglodytes	80.89	0.00e+00	1071.00
IUUC-Psi-093963	Pelodiscus sinensis	54.92	0.00e+00	1641.00
IUUC-Pfo-096197	Poecilia formosa	34.67	0.00e+00	828.00
IUUC-Pab-097755	Pongo abelii	80.36	0.00e+00	907.00
IUUC-Pca-100809	Procavia capensis	78.73	0.00e+00	1219.00
IUUC-Pva-102554	Pteropus vampyrus	84.08	0.00e+00	2316.00
IUUC-Rno-105174	Rattus norvegicus	70.24	0.00e+00	2097.00
IUUC-Sha-107304	Sarcophilus harrisii	62.08	0.00e+00	2004.00
IUUC-Sar-113168	Sorex araneus	66.75	0.00e+00	1401.00
IUUC-Tru-118251	Takifugu rubripes	35.45	0.00e+00	662.00
IUUC-Tsy-119276	Tarsius syrichta	77.54	2.00e-116	414.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence