iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052342

Ensembl Protein ID

ENSLOCP00000015930.1

UniProt Accession

W5N5M1; W5N5M1_LEPOC

Genbank Protein ID

ENSLOCP00000015930

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

AHAT01001948

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000012930.1	ENSLOCT00000015960.1	ENSLOCP00000015930.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	4.10e-59	200.7	2	227

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 4    qvkewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffak 92
            ++ew ++e +P++++++++++gv + +++ ++ + + e l+++++p ++++llF++++++e++r +q t  +l  + ++i  +++f+k
   Q: 2    TAMEWKPMEINPEMLNKVLSKLGVGDSWRFVDVLGFEDEPLASVPKPSCAVMLLFPLTPQHETFREKQST--ELAEKAKEI-PSVYFIK 87
           568**************************************************************88855..777777775.69***** PP
   S: 93   qvigNsCatyAllsvllncedkl.ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhf 180
           q+i NsC+t +ll++++n++dkl +  G+ l+ ++++t ++s+e++a++l+++q+++ +h+ +a +++++ +e          k +fhf
   Q: 88   QTIVNSCGTVGLLHAVANNKDKLeFKSGSALKSFLDKTASMSAEDRAKELEKSQAIHTAHDEVAAEGQCRVEED---------KVNFHF 167
           *********************************************************************99954.........589*** PP
   S: 181  vsyvningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesdeirfnllaivad 244
           ++++n++g+lyeldg++ +P+d+g++k++  + d++k +r+f+er    e++e+rf+++a++++
   Q: 168  ITFINVDGHLYELDGRMSVPVDHGATKDDSFIMDAAKICRQFVER----EKGEVRFSAVALCKA 227
           *********************************************....9***********987 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

STAMEWKPME INPEMLNKVL SKLGVGDSWR FVDVLGFEDE PLASVPKPSC AVMLLFPLTP 60
QHETFREKQS TELAEKAKEI PSVYFIKQTI VNSCGTVGLL HAVANNKDKL EFKSGSALKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCTCTCGC AGGCGCTGCA CAGCTCTTTC GAACTGGCAA GCTCCCCCGT GGGTATTTGC 60
TAGCAACTTC CAGACGAATC ATGCGACCTG GACTGTGCTA TTATTTCCAG TCTCCACAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR030297--UCHL1

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0016874--F:ligase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001376	Ailuropoda melanoleuca	58.69	3.00e-78	284.00
IUUC-Apl-003693	Anas platyrhynchos	60.18	1.00e-77	281.00
IUUC-Aca-004716	Anolis carolinensis	64.60	7.00e-89	319.00
IUUC-Ame-011806	Astyanax mexicanus	72.32	2.00e-95	341.00
IUUC-Bta-013521	Bos taurus	59.22	5.00e-80	290.00
IUUC-Cja-018752	Callithrix jacchus	69.60	2.00e-82	298.00
IUUC-Cfa-020442	Canis familiaris	69.60	9.00e-83	299.00
IUUC-Cpo-021723	Cavia porcellus	69.82	2.00e-65	241.00
IUUC-Csa-023626	Chlorocebus sabaeus	69.91	2.00e-83	301.00
IUUC-Cho-024548	Choloepus hoffmanni	60.91	2.00e-26	112.00
IUUC-Dre-027854	Danio rerio	70.54	6.00e-94	336.00
IUUC-Dno-029325	Dasypus novemcinctus	69.47	3.00e-83	301.00
IUUC-Dor-030114	Dipodomys ordii	69.91	2.00e-92	331.00
IUUC-Ete-033092	Echinops telfairi	56.64	5.00e-67	246.00
IUUC-Eeu-034493	Erinaceus europaeus	68.14	2.00e-80	291.00
IUUC-Fal-036693	Ficedula albicollis	66.98	2.00e-84	305.00
IUUC-Gmo-038848	Gadus morhua	70.89	6.00e-91	326.00
IUUC-Gga-041078	Gallus gallus	66.37	1.00e-90	325.00
IUUC-Gac-042064	Gasterosteus aculeatus	69.68	3.00e-93	333.00
IUUC-Ggo-044827	Gorilla gorilla	70.35	4.00e-84	303.00
IUUC-Hsa-045820	Homo sapiens	70.35	4.00e-84	303.00
IUUC-Itr-048496	Ictidomys tridecemlineatus	69.03	8.00e-83	299.00
IUUC-Lch-050121	Latimeria chalumnae	69.96	7.00e-91	326.00
IUUC-Laf-053916	Loxodonta africana	69.43	4.00e-83	300.00
IUUC-Mcc-054838	Macaca mulatta	69.91	2.00e-83	301.00
IUUC-Meu-056478	Macropus eugenii	69.03	3.00e-91	327.00
IUUC-Mga-059878	Meleagris gallopavo	64.38	4.00e-83	300.00
IUUC-Mdo-062544	Monodelphis domestica	66.81	2.00e-80	291.00
IUUC-Mmu-063300	Mus musculus	70.35	5.00e-93	333.00
IUUC-Mpu-066128	Mustela putorius furo	67.82	2.00e-70	258.00
IUUC-Mlu-067778	Myotis lucifugus	69.78	6.00e-92	329.00
IUUC-Nle-069686	Nomascus leucogenys	69.91	8.00e-84	302.00
IUUC-Opr-070535	Ochotona princeps	58.41	3.00e-69	254.00
IUUC-Ont-071510	Oreochromis niloticus	69.51	1.00e-93	335.00
IUUC-Ocu-074590	Oryctolagus cuniculus	69.91	8.00e-84	302.00
IUUC-Ola-087552	Oryzias latipes	63.76	4.00e-84	303.00
IUUC-Oga-089013	Otolemur garnettii	59.22	8.00e-80	289.00
IUUC-Oar-089861	Ovis aries	59.22	4.00e-80	290.00
IUUC-Ptr-091536	Pan troglodytes	68.58	2.00e-81	295.00
IUUC-Pan-092909	Papio anubis	69.91	2.00e-83	301.00
IUUC-Psi-093818	Pelodiscus sinensis	68.58	3.00e-91	327.00
IUUC-Pfo-097335	Poecilia formosa	62.83	1.00e-84	305.00
IUUC-Pab-098048	Pongo abelii	70.35	4.00e-84	303.00
IUUC-Pca-100818	Procavia capensis	53.57	2.00e-47	181.00
IUUC-Pva-102954	Pteropus vampyrus	69.47	1.00e-80	291.00
IUUC-Pyt-104587	Pyrenophora triticirepentis	37.32	5.00e-31	127.00
IUUC-Rno-105966	Rattus norvegicus	70.35	5.00e-93	333.00
IUUC-Spo-108322	Schizosaccharomyces pombe	30.84	1.00e-25	109.00
IUUC-Sar-113190	Sorex araneus	52.63	7.00e-23	98.60
IUUC-Ssc-115908	Sus scrofa	58.77	4.00e-71	260.00
IUUC-Tgu-117465	Taeniopygia guttata	63.38	2.00e-78	284.00
IUUC-Tru-118565	Takifugu rubripes	63.84	3.00e-80	291.00
IUUC-Tsy-119561	Tarsius syrichta	56.19	3.00e-66	244.00
IUUC-Tbe-128048	Tupaia belangeri	67.86	9.00e-64	235.00
IUUC-Ttr-128494	Tursiops truncatus	67.56	2.00e-79	288.00
IUUC-Vda-129850	Verticillium dahliae	33.33	9.00e-29	120.00
IUUC-Xtr-132286	Xenopus tropicalis	67.11	3.00e-87	314.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence