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Basic Information Integrated Annotations

Tag Content
UUCD2 ID IUUC-Mmu-063534
UUCD1 version UUC-MuM-00919
Ensembl Protein ID ENSMUSP00000033549.2
UniProt Accession Q9D738; ASB12_MOUSE
Genbank Protein ID BAB26410.1; AAL57359.1
Protein Name Ankyrin repeat and SOCS box protein 12
Genbank Nucleotide ID AK009644; AF403040
Gene Name Asb12
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000031204.3 ENSMUST00000033549.2 ENSMUSP00000033549.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarmiRNAMap
RAID2
Protein-protein Interaction
IIDiRefIndexMentha
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box 88.64 2.00e-153 539.00 IUUC-Hsa-046866
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mus musculus
Functional Description
(View)

Functional Description



     Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Protein Sequence
(Fasta)
MNLMDIAKIF SLLQPEKEEE DTGTGEKQAL NQAVYDNDSC TLDHLLHQER YKRFINSRSG 60
WGIPGTPLRL AASYGHLNCV KVLLEHGADV DSLDVKAQTP LFTAVSHGHL ECVRMLLEAG 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Mmu-063534|E3,SOCS|Mus musculus
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Nucleotide Sequence
(Fasta)
ATGGTCAGTA AGACAAGGGA AGTAAATCTA CTTCCCCGAT TACTATGGGA AGAACATAGC 60
TTCCAACAGG TGAGTAGAGT AGAAACATGT AAAAAACTGA GTTGTAAGCT TGAGTGTAAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mmu-063534|E3,SOCS|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR001496--SOCS_box

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT

Pfam

PF00023--Ank
PF07525--SOCS_box

SMART

SM00248--ANK
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination

KEGG mmu:70392
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001687 Ailuropoda melanoleuca 85.39 1.00e-153 535.00
IUUC-Apl-003316 Anas platyrhynchos 63.64 7.00e-112 396.00
IUUC-Aca-004677 Anolis carolinensis 62.66 6.00e-110 390.00
IUUC-Ame-011686 Astyanax mexicanus 62.21 3.00e-108 384.00
IUUC-Bta-013050 Bos taurus 85.90 2.00e-153 534.00
IUUC-Cfa-020331 Canis familiaris 87.34 1.00e-158 551.00
IUUC-Cpo-021837 Cavia porcellus 85.71 9.00e-155 539.00
IUUC-Csa-023302 Chlorocebus sabaeus 89.61 3.00e-157 547.00
IUUC-Dre-028542 Danio rerio 59.09 2.00e-104 371.00
IUUC-Dno-029108 Dasypus novemcinctus 87.34 5.00e-160 556.00
IUUC-Eca-033539 Equus caballus 85.06 1.00e-148 518.00
IUUC-Fca-035885 Felis catus 87.34 2.00e-150 525.00
IUUC-Fal-036760 Ficedula albicollis 62.99 3.00e-108 384.00
IUUC-Gmo-038774 Gadus morhua 59.61 1.00e-104 372.00
IUUC-Gga-040432 Gallus gallus 66.34 1.00e-120 426.00
IUUC-Gac-042345 Gasterosteus aculeatus 57.47 2.00e-94 338.00
IUUC-Ggo-044738 Gorilla gorilla 89.29 4.00e-157 546.00
IUUC-Hsa-046866 Homo sapiens 88.64 2.00e-155 541.00
IUUC-Itr-048720 Ictidomys tridecemlineatus 87.99 4.00e-162 563.00
IUUC-Lch-050001 Latimeria chalumnae 60.39 2.00e-115 408.00
IUUC-Laf-053954 Loxodonta africana 90.26 3.00e-158 550.00
IUUC-Meu-056024 Macropus eugenii 76.42 2.00e-111 394.00
IUUC-Mga-059306 Meleagris gallopavo 66.99 7.00e-123 433.00
IUUC-Mmr-060921 Microcebus murinus 87.99 7.00e-160 556.00
IUUC-Mdo-062338 Monodelphis domestica 72.40 4.00e-127 447.00
IUUC-Mpu-066393 Mustela putorius furo 87.01 7.00e-158 549.00
IUUC-Mlu-067956 Myotis lucifugus 82.14 4.00e-153 535.00
IUUC-Nle-069144 Nomascus leucogenys 89.61 3.00e-157 547.00
IUUC-Opr-071120 Ochotona princeps 72.08 3.00e-124 437.00
IUUC-Ont-072016 Oreochromis niloticus 61.49 2.00e-102 365.00
IUUC-Ocu-074678 Oryctolagus cuniculus 88.64 5.00e-163 566.00
IUUC-Ola-086912 Oryzias latipes 59.74 1.00e-101 362.00
IUUC-Oga-087915 Otolemur garnettii 88.96 3.00e-156 543.00
IUUC-Ptr-091446 Pan troglodytes 88.96 2.00e-156 545.00
IUUC-Pan-092113 Papio anubis 89.61 2.00e-157 548.00
IUUC-Psi-093998 Pelodiscus sinensis 65.91 2.00e-122 431.00
IUUC-Pfo-097085 Poecilia formosa 59.74 4.00e-107 380.00
IUUC-Pab-098363 Pongo abelii 89.29 5.00e-157 546.00
IUUC-Pca-100842 Procavia capensis 87.34 3.00e-159 554.00
IUUC-Rno-105361 Rattus norvegicus 96.75 6.00e-177 612.00
IUUC-Sar-113567 Sorex araneus 65.26 1.00e-102 366.00
IUUC-Tgu-117142 Taeniopygia guttata 57.78 2.00e-60 224.00
IUUC-Tru-118185 Takifugu rubripes 59.61 4.00e-108 384.00
IUUC-Tni-120054 Tetraodon nigroviridis 59.74 8.00e-104 370.00
IUUC-Ttr-129120 Tursiops truncatus 87.99 2.00e-151 528.00
IUUC-Xtr-131874 Xenopus tropicalis 53.87 1.00e-83 303.00
Created Date 25-Jun-2017

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