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Tag Content
iUUCD ID IUUC-Olu-087811
Ensembl Protein ID ABO98232
UniProt Accession A4S3L3; A4S3L3_OSTLU
Genbank Protein ID ABO98232.1
Protein Name Presenilin
Genbank Nucleotide ID CP000590
Gene Name OSTLU_46801
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
OSTLU_46801 ABO98232 ABO98232
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/CUE 31.50 5.00e-37 151.00 IUUC-Cel-018553
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Ostreococcus lucimarinus
Functional Description
(View)

Functional Description


     Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
 Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
Protein Sequence
(Fasta)
MASSIGAVVV PVAIAMALCV WLVTLLRGDA TEDAEATSGG VISAVYTEKS GDSEYVKFTG 60
SVENAAVFVG FITAMTFALF LLFKYRMGKV IWAYMGFSGL LIFGVLGGNI LMRVLQKLDI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Olu-087811|UBD,CUE|Ostreococcus lucimarinus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGGCCGACGT TCGGCGCCAT GGCGTCATCC ATAGGCGCTG TGGTCGTCCC CGTCGCGATC 60
GCGATGGCGC TCTGCGTGTG GTTGGTGACG CTGTTGCGCG GTGACGCCAC CGAAGACGCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Olu-087811|UBD,CUE|Ostreococcus lucimarinus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP
Pfam

PF01080--Presenilin
PRINTS

PR01072--PRESENILIN
SMART

SM00730--PSN
Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0004190--F:aspartic-type endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing
KEGG olu:OSTLU_46801
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000686 Aegilops tauschii 42.72 8.00e-23 100.00
IUUC-Aml-001648 Ailuropoda melanoleuca 36.67 1.00e-37 148.00
IUUC-Atr-003039 Amborella trichopoda 40.55 1.00e-39 154.00
IUUC-Apl-003727 Anas platyrhynchos 35.46 3.00e-34 136.00
IUUC-Aca-004582 Anolis carolinensis 34.00 4.00e-35 140.00
IUUC-Aly-005455 Arabidopsis lyrata 41.20 2.00e-37 147.00
IUUC-Ath-006730 Arabidopsis thaliana 41.67 2.00e-38 150.00
IUUC-Afu-009010 Aspergillus fumigatus 40.74 6.30e+00 23.90
IUUC-Ame-010686 Astyanax mexicanus 36.17 1.00e-34 138.00
IUUC-Bta-013097 Bos taurus 35.48 6.00e-36 142.00
IUUC-Bdi-014196 Brachypodium distachyon 45.26 4.00e-27 113.00
IUUC-Bol-015841 Brassica oleracea 40.28 1.00e-31 128.00
IUUC-Bra-017580 Brassica rapa 46.86 1.00e-30 124.00
IUUC-Cel-018553 Caenorhabditis elegans 31.50 1.00e-34 138.00
IUUC-Cja-019994 Callithrix jacchus 35.46 5.00e-38 149.00
IUUC-Cfa-020074 Canis familiaris 36.69 2.00e-39 154.00
IUUC-Cpo-022237 Cavia porcellus 35.20 6.00e-39 152.00
IUUC-Cre-022747 Chlamydomonas reinhardtii 42.55 6.00e-47 179.00
IUUC-Csa-023537 Chlorocebus sabaeus 36.97 9.00e-39 152.00
IUUC-Cho-024735 Choloepus hoffmanni 37.59 3.00e-34 137.00
IUUC-Cin-025780 Ciona intestinalis 34.69 5.00e-44 169.00
IUUC-Csv-025967 Ciona savignyi 35.56 3.00e-33 133.00
IUUC-Dre-028526 Danio rerio 38.28 2.00e-38 150.00
IUUC-Dno-029758 Dasypus novemcinctus 36.69 2.00e-37 147.00
IUUC-Dor-031127 Dipodomys ordii 38.15 2.00e-36 144.00
IUUC-Dme-031929 Drosophila melanogaster 34.91 3.00e-31 127.00
IUUC-Ete-033081 Echinops telfairi 30.30 2.00e-12 64.70
IUUC-Eca-034387 Equus caballus 38.18 2.00e-35 140.00
IUUC-Eeu-035134 Erinaceus europaeus 37.37 2.00e-35 140.00
IUUC-Fca-036243 Felis catus 36.97 3.00e-40 157.00
IUUC-Fal-036600 Ficedula albicollis 35.85 2.00e-35 140.00
IUUC-Gmo-039665 Gadus morhua 33.68 8.00e-33 132.00
IUUC-Gga-040993 Gallus gallus 34.44 7.00e-36 142.00
IUUC-Gac-042511 Gasterosteus aculeatus 35.71 9.00e-38 148.00
IUUC-Gma-043822 Glycine max 42.33 1.00e-35 141.00
IUUC-Ggo-045338 Gorilla gorilla 38.18 3.00e-35 140.00
IUUC-Hsa-046822 Homo sapiens 36.97 9.00e-39 152.00
IUUC-Hvu-047141 Hordeum vulgare 41.78 2.00e-24 104.00
IUUC-Itr-048731 Ictidomys tridecemlineatus 38.18 2.00e-35 140.00
IUUC-Lch-049638 Latimeria chalumnae 35.71 2.00e-31 127.00
IUUC-Lpe-051132 Leersia perrieri 46.72 1.00e-25 108.00
IUUC-Loc-052427 Lepisosteus oculatus 36.81 7.00e-38 149.00
IUUC-Laf-053758 Loxodonta africana 37.28 3.00e-37 147.00
IUUC-Mcc-055682 Macaca mulatta 36.97 9.00e-39 152.00
IUUC-Meu-056004 Macropus eugenii 33.76 3.00e-27 114.00
IUUC-Mtr-058392 Medicago truncatula 31.44 6.00e-31 125.00
IUUC-Mga-059466 Meleagris gallopavo 34.10 2.00e-35 140.00
IUUC-Mmr-060890 Microcebus murinus 37.82 4.00e-35 140.00
IUUC-Mdo-062122 Monodelphis domestica 36.19 3.00e-36 143.00
IUUC-Mmu-063823 Mus musculus 38.73 3.00e-36 143.00
IUUC-Mac-064858 Musa acuminata 47.24 1.00e-23 100.00
IUUC-Mpu-065927 Mustela putorius furo 36.97 2.00e-39 154.00
IUUC-Mlu-067079 Myotis lucifugus 34.52 4.00e-43 166.00
IUUC-Nle-070180 Nomascus leucogenys 36.97 9.00e-39 152.00
IUUC-Opr-070344 Ochotona princeps 37.09 2.00e-35 140.00
IUUC-Ont-071867 Oreochromis niloticus 38.14 9.00e-40 155.00
IUUC-Oan-072783 Ornithorhynchus anatinus 36.20 5.00e-32 129.00
IUUC-Ocu-074527 Oryctolagus cuniculus 37.88 3.00e-39 153.00
IUUC-Oba-075256 Oryza barthii 50.00 2.00e-25 107.00
IUUC-Obr-076302 Oryza brachyantha 46.72 6.00e-26 109.00
IUUC-Ogl-077097 Oryza glaberrima 47.45 6.00e-26 109.00
IUUC-Ogu-078570 Oryza glumaepatula 47.45 5.00e-26 109.00
IUUC-Oin-079244 Oryza indica 47.45 4.00e-26 110.00
IUUC-Olo-080484 Oryza longistaminata 50.00 2.00e-16 77.40
IUUC-Ome-081814 Oryza meridionalis 47.45 3.00e-26 110.00
IUUC-Oni-082057 Oryza nivara 47.45 4.00e-26 109.00
IUUC-Opu-084176 Oryza punctata 46.72 1.00e-25 108.00
IUUC-Oru-084618 Oryza rufipogon 47.45 4.00e-26 109.00
IUUC-Osa-085602 Oryza sativa 47.45 5.00e-26 109.00
IUUC-Ola-086707 Oryzias latipes 35.05 3.00e-29 119.00
IUUC-Oga-088560 Otolemur garnettii 37.05 3.00e-34 137.00
IUUC-Oar-090348 Ovis aries 36.41 8.00e-40 155.00
IUUC-Ptr-091060 Pan troglodytes 36.97 9.00e-39 152.00
IUUC-Pan-091742 Papio anubis 38.18 2.00e-35 140.00
IUUC-Psi-093505 Pelodiscus sinensis 34.43 3.00e-35 140.00
IUUC-Pma-094612 Petromyzon marinus 35.36 6.00e-33 132.00
IUUC-Ppa-095431 Physcomitrella patens 46.33 6.00e-43 166.00
IUUC-Pfo-097396 Poecilia formosa 32.82 3.00e-36 143.00
IUUC-Pab-098591 Pongo abelii 36.97 1.00e-38 152.00
IUUC-Pop-099661 Populus trichocarpa 39.63 1.00e-54 204.00
IUUC-Pca-101029 Procavia capensis 37.63 2.00e-33 134.00
IUUC-Ppe-101495 Prunus persica 42.15 1.00e-39 155.00
IUUC-Pva-102934 Pteropus vampyrus 35.51 2.00e-36 144.00
IUUC-Rno-106052 Rattus norvegicus 38.73 6.00e-40 155.00
IUUC-Sha-107045 Sarcophilus harrisii 35.93 3.00e-36 143.00
IUUC-Smo-109325 Selaginella moellendorffii 37.31 2.00e-46 177.00
IUUC-Sit-110624 Setaria italica 45.14 8.00e-21 92.40
IUUC-Sly-110865 Solanum lycopersicum 46.77 2.00e-07 45.10
IUUC-Stu-112433 Solanum tuberosum 38.52 4.00e-35 139.00
IUUC-Sar-113169 Sorex araneus 35.49 5.00e-31 126.00
IUUC-Sbi-114305 Sorghum bicolor 45.99 7.00e-21 92.80
IUUC-Ssc-115766 Sus scrofa 37.82 4.00e-39 153.00
IUUC-Tgu-116469 Taeniopygia guttata 36.75 1.00e-34 137.00
IUUC-Tru-117732 Takifugu rubripes 33.59 2.00e-33 134.00
IUUC-Tsy-119624 Tarsius syrichta 33.50 2.00e-35 141.00
IUUC-Tni-119852 Tetraodon nigroviridis 32.07 2.00e-30 124.00
IUUC-Tca-121865 Theobroma cacao 48.57 4.00e-38 149.00
IUUC-Tae-123984 Triticum aestivum 42.72 2.00e-23 100.00
IUUC-Tur-126237 Triticum urartu 45.26 6.00e-21 92.80
IUUC-Tbe-127632 Tupaia belangeri 37.77 3.00e-33 133.00
IUUC-Ttr-129008 Tursiops truncatus 34.84 6.00e-35 139.00
IUUC-Vpa-130625 Vicugna pacos 35.64 8.00e-30 122.00
IUUC-Vvi-131312 Vitis vinifera 46.86 1.00e-36 144.00
IUUC-Xtr-132756 Xenopus tropicalis 37.78 3.00e-38 150.00
IUUC-Xma-133377 Xiphophorus maculatus 32.74 7.00e-36 142.00
Created Date 25-Jun-2017

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