iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059579

UUCD1 version

UUC-MeG-00106

Ensembl Protein ID

ENSMGAP00000001662.2

UniProt Accession

G1MTD7; G1MTD7_MELGA

Protein Name

Uncharacterized protein

Gene Name

SPOP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000002099.2	ENSMGAT00000002326.2	ENSMGAP00000001662.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.50e-33	112.9	200	266
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.20e-08	31.7	299	326

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +D++l+v+g+ef+ahk++Laa+S+vF+a+f++e+eesk k++vei+dv+pevf+++++F+Ytgk+++ 
   Q: 200  TDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESK-KNRVEINDVEPEVFKEMMCFIYTGKAPNL 266
           7*************************************.*************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfil 28
           +eN+++il +Adl+++++Lk +a+dfi+
   Q: 299  VENAAEILILADLHSADQLKTQAVDFIN 326
           79*************************7 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MSRVPSPPPP AEMSSGPVAE SWCYTQIKVV KFSYMWTINN FSFCREEMGE VIKSSTFSSG 60
ANDKLKWCLR VNPKGLDEES KDYLSLYLLL VSCPKSEVRA KFKFSILNAK GEETKAMESQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAAGGG TGCCAAGTCC TCCTCCTCCG GCAGAAATGT CGAGTGGACC CGTGGCAGAA 60
AGCTGGTGCT ACACTCAGGT GAGATTGCGC TGTGTTGGGC TGTTCTCGAG GCTGCCCAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR002083--MATH/TRAF_dom
IPR011333--SKP1/BTB/POZ
IPR034089--SPOP_C
IPR008974--TRAF-like

PROSITE

PS50097--BTB
PS50144--MATH

Pfam

PF00651--BTB
PF00917--MATH

SMART

SM00225--BTB
SM00061--MATH

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016607--C:nuclear speck
GO:0042593--P:glucose homeostasis
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:1902237--P:positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:2000676--P:positive regulation of type B pancreatic cell apoptotic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002307	Ailuropoda melanoleuca	95.17	0.00e+00	702.00
IUUC-Apl-003488	Anas platyrhynchos	95.41	0.00e+00	702.00
IUUC-Aca-005010	Anolis carolinensis	95.15	0.00e+00	700.00
IUUC-Aly-005426	Arabidopsis lyrata	31.56	2.00e-39	156.00
IUUC-Aor-009945	Aspergillus oryzae	38.46	2.00e-04	36.60
IUUC-Bta-012931	Bos taurus	95.15	0.00e+00	701.00
IUUC-Cel-018671	Caenorhabditis elegans	62.94	2.00e-132	464.00
IUUC-Cja-019981	Callithrix jacchus	94.91	0.00e+00	696.00
IUUC-Cfa-020115	Canis familiaris	95.15	0.00e+00	701.00
IUUC-Cpo-021366	Cavia porcellus	94.66	0.00e+00	694.00
IUUC-Cre-022954	Chlamydomonas reinhardtii	30.99	2.00e-06	48.10
IUUC-Cgl-026729	Colletotrichum gloeosporioides	30.30	6.00e-06	44.70
IUUC-Dre-027603	Danio rerio	93.11	0.00e+00	685.00
IUUC-Dno-029006	Dasypus novemcinctus	89.42	0.00e+00	632.00
IUUC-Dor-030503	Dipodomys ordii	95.10	0.00e+00	693.00
IUUC-Ete-032328	Echinops telfairi	94.26	0.00e+00	640.00
IUUC-Eca-033238	Equus caballus	95.15	0.00e+00	701.00
IUUC-Eeu-034739	Erinaceus europaeus	79.85	4.00e-172	596.00
IUUC-Fca-035435	Felis catus	95.15	0.00e+00	701.00
IUUC-Gmo-038600	Gadus morhua	91.84	0.00e+00	680.00
IUUC-Ggr-039811	Gaeumannomyces graminis	32.88	4.00e-08	52.00
IUUC-Gga-040441	Gallus gallus	95.41	0.00e+00	702.00
IUUC-Gac-041911	Gasterosteus aculeatus	92.60	0.00e+00	684.00
IUUC-Hsa-045835	Homo sapiens	95.15	0.00e+00	701.00
IUUC-Itr-048058	Ictidomys tridecemlineatus	93.02	0.00e+00	667.00
IUUC-Lch-050241	Latimeria chalumnae	94.39	0.00e+00	697.00
IUUC-Loc-052374	Lepisosteus oculatus	94.64	0.00e+00	697.00
IUUC-Laf-054192	Loxodonta africana	94.91	0.00e+00	696.00
IUUC-Mcc-055322	Macaca mulatta	95.15	0.00e+00	701.00
IUUC-Meu-056330	Macropus eugenii	88.78	0.00e+00	649.00
IUUC-Mor-057237	Magnaporthe oryzae	29.41	8.00e-08	50.40
IUUC-Mpo-057466	Magnaporthe poae	28.36	6.00e-08	50.40
IUUC-Mmr-061309	Microcebus murinus	95.15	0.00e+00	701.00
IUUC-Mmu-064227	Mus musculus	95.15	0.00e+00	701.00
IUUC-Mpu-065693	Mustela putorius furo	95.15	0.00e+00	701.00
IUUC-Mlu-067827	Myotis lucifugus	94.66	0.00e+00	695.00
IUUC-Nle-069393	Nomascus leucogenys	95.15	0.00e+00	701.00
IUUC-Opr-070490	Ochotona princeps	93.37	0.00e+00	686.00
IUUC-Ont-071726	Oreochromis niloticus	92.86	0.00e+00	687.00
IUUC-Ocu-074932	Oryctolagus cuniculus	95.15	0.00e+00	701.00
IUUC-Obr-076031	Oryza brachyantha	26.73	9.00e-30	124.00
IUUC-Olo-080833	Oryza longistaminata	31.94	6.00e-37	147.00
IUUC-Opu-083303	Oryza punctata	31.27	8.00e-28	118.00
IUUC-Ola-086989	Oryzias latipes	92.62	0.00e+00	682.00
IUUC-Olu-087691	Ostreococcus lucimarinus	30.46	4.00e-33	134.00
IUUC-Oga-089107	Otolemur garnettii	95.15	0.00e+00	701.00
IUUC-Oar-089943	Ovis aries	94.91	0.00e+00	696.00
IUUC-Ptr-091201	Pan troglodytes	95.15	0.00e+00	701.00
IUUC-Pan-092504	Papio anubis	95.15	0.00e+00	701.00
IUUC-Psi-093063	Pelodiscus sinensis	95.41	0.00e+00	702.00
IUUC-Ppa-095322	Physcomitrella patens	32.19	2.00e-40	159.00
IUUC-Pfo-096411	Poecilia formosa	92.86	0.00e+00	687.00
IUUC-Pab-098640	Pongo abelii	95.15	0.00e+00	701.00
IUUC-Pop-099477	Populus trichocarpa	32.40	2.00e-40	158.00
IUUC-Pca-100243	Procavia capensis	99.49	2.00e-108	384.00
IUUC-Pva-102296	Pteropus vampyrus	88.52	0.00e+00	635.00
IUUC-Pyt-104526	Pyrenophora triticirepentis	23.53	8.00e-07	47.40
IUUC-Rno-105399	Rattus norvegicus	95.15	0.00e+00	701.00
IUUC-Sha-106700	Sarcophilus harrisii	95.15	0.00e+00	700.00
IUUC-Spo-108262	Schizosaccharomyces pombe	36.84	7.90e-02	32.30
IUUC-Ssl-108548	Sclerotinia sclerotiorum	28.77	1.00e-06	47.00
IUUC-Smo-108684	Selaginella moellendorffii	31.52	6.00e-31	127.00
IUUC-Sit-110036	Setaria italica	32.39	5.00e-39	154.00
IUUC-Sly-110931	Solanum lycopersicum	29.33	2.00e-40	159.00
IUUC-Stu-112216	Solanum tuberosum	29.87	3.00e-40	158.00
IUUC-Sar-113489	Sorex araneus	95.15	0.00e+00	701.00
IUUC-Tru-117832	Takifugu rubripes	92.09	0.00e+00	681.00
IUUC-Tsy-118969	Tarsius syrichta	90.31	0.00e+00	657.00
IUUC-Tni-120221	Tetraodon nigroviridis	92.09	0.00e+00	681.00
IUUC-Tbe-127298	Tupaia belangeri	94.90	0.00e+00	689.00
IUUC-Ttr-128952	Tursiops truncatus	94.90	0.00e+00	700.00
IUUC-Vpa-130735	Vicugna pacos	89.54	0.00e+00	634.00
IUUC-Vvi-131448	Vitis vinifera	31.03	3.00e-41	162.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence