iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062880

UUCD1 version

UUC-MoD-00636

Ensembl Protein ID

ENSMODP00000010693.2

UniProt Accession

F7BTY5; F7BTY5_MONDO

Protein Name

Uncharacterized protein

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000008598.3	ENSMODT00000010905.3	ENSMODP00000010693.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-39	131.9	630	665
UBD/Beta-Prp	1.20e-66	225.0	50	259

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtg 33
           gHt+++t+la+   +d++lvs+++Dgt +vWD+ + 
   Q: 630  GHTAKITSLAWsphHDGRLVSACYDGTAQVWDVLRE 665
           8***********8766****************8665 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqc 128
           +l +l gh++ v+  +fs++     + +++s+D+t+k+wd+ t++ v   + h++++ +l++sp  +d ++sG++  ++ ++ ++++  
   Q: 50   VLGELVGHTERVSGFTFSHHVGqtnFCASSSDDGTVKIWDVYTRTVVTEHTLHQNTISALHWSPkVKDLIISGDEKGIVICY-WNNRND 137
           47899*************9866677***************************************555**************7.666666 PP
   S: 129  leetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls...........fdsng............ 192
           ++  + ++ +++ c++ +p   +l++ G +D++v + d+ + g++l++l+g h+d ++s++           +   +            
   Q: 138  SQ-HFFPEPRTIFCITCSPHHeDLVAMGYKDGMVVVIDIsRKGDILHRLRG-HDDEIHSIAwcpllgedcltI---Rpeensdeheipn 221
           66.6788888899998888888*****************999********9.*********766666666662...0444667778888 PP
   S: 193  ............kelvsgsldgtvklwdlqtgecvrtl 218
                        +l++gs+d+t+++w++++g+ v+tl
   Q: 222  gkvvqqtpvtkdCYLATGSKDQTIRIWSCSRGRGVMTL 259
           8888889999999*******************999987 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MGPETRMLTP SPNWYCSRSS DAGPGGLFGF AARNSVYLLQ IGLGQSPFHV LGELVGHTER 60
VSGFTFSHHV GQTNFCASSS DDGTVKIWDV YTRTVVTEHT LHQNTISALH WSPKVKDLII 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTTCCCAG GATCAGGAGA ACGCGTTCTC TGCGGCATGG CCCTCTGTGC GAACCGTAGG 60
AGAAGGGGCA AGCGGGGGAC ATGAGGGGGG CGGGGCCGGA GGAGTTTGCT CTCTTTTCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

KEGG

mdo:100029821

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	73.76	0.00e+00	2189.00
IUUC-Apl-003586	Anas platyrhynchos	65.89	0.00e+00	1773.00
IUUC-Aca-004956	Anolis carolinensis	64.92	0.00e+00	1957.00
IUUC-Ame-010753	Astyanax mexicanus	63.76	0.00e+00	1022.00
IUUC-Bta-012315	Bos taurus	73.68	0.00e+00	2202.00
IUUC-Cja-019334	Callithrix jacchus	73.07	0.00e+00	2209.00
IUUC-Cfa-021254	Canis familiaris	74.62	0.00e+00	2258.00
IUUC-Cpo-021984	Cavia porcellus	69.33	0.00e+00	2018.00
IUUC-Csa-023650	Chlorocebus sabaeus	73.59	0.00e+00	2182.00
IUUC-Cho-024860	Choloepus hoffmanni	70.12	0.00e+00	2062.00
IUUC-Cin-025778	Ciona intestinalis	38.24	0.00e+00	681.00
IUUC-Csv-026313	Ciona savignyi	41.71	8.00e-168	583.00
IUUC-Dre-028096	Danio rerio	65.88	0.00e+00	1038.00
IUUC-Dno-029799	Dasypus novemcinctus	77.27	0.00e+00	1954.00
IUUC-Dor-030885	Dipodomys ordii	76.39	1.00e-142	501.00
IUUC-Ete-032918	Echinops telfairi	69.11	0.00e+00	2063.00
IUUC-Eca-034144	Equus caballus	73.05	0.00e+00	2165.00
IUUC-Eeu-034843	Erinaceus europaeus	68.62	0.00e+00	1545.00
IUUC-Fca-035948	Felis catus	73.84	0.00e+00	2204.00
IUUC-Fal-037303	Ficedula albicollis	64.01	0.00e+00	1897.00
IUUC-Gmo-039591	Gadus morhua	53.79	0.00e+00	844.00
IUUC-Gga-040570	Gallus gallus	64.49	0.00e+00	1746.00
IUUC-Gac-042646	Gasterosteus aculeatus	52.39	0.00e+00	1347.00
IUUC-Ggo-045605	Gorilla gorilla	69.94	0.00e+00	1589.00
IUUC-Hsa-046122	Homo sapiens	73.93	0.00e+00	2185.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	77.79	0.00e+00	1978.00
IUUC-Lch-050489	Latimeria chalumnae	51.38	0.00e+00	914.00
IUUC-Loc-052259	Lepisosteus oculatus	64.22	0.00e+00	1015.00
IUUC-Laf-053338	Loxodonta africana	74.25	0.00e+00	2222.00
IUUC-Mcc-055442	Macaca mulatta	73.79	0.00e+00	2185.00
IUUC-Meu-056245	Macropus eugenii	80.67	0.00e+00	1036.00
IUUC-Mga-060202	Meleagris gallopavo	64.70	0.00e+00	1813.00
IUUC-Mmr-061730	Microcebus murinus	73.28	0.00e+00	2184.00
IUUC-Mmu-063930	Mus musculus	70.95	0.00e+00	2054.00
IUUC-Mpu-066605	Mustela putorius furo	73.87	0.00e+00	2227.00
IUUC-Mlu-067765	Myotis lucifugus	73.32	0.00e+00	2228.00
IUUC-Nle-069183	Nomascus leucogenys	73.88	0.00e+00	2151.00
IUUC-Opr-070659	Ochotona princeps	62.56	0.00e+00	962.00
IUUC-Ont-072356	Oreochromis niloticus	62.12	0.00e+00	1011.00
IUUC-Oan-073056	Ornithorhynchus anatinus	76.72	0.00e+00	2187.00
IUUC-Ocu-073881	Oryctolagus cuniculus	73.67	0.00e+00	2253.00
IUUC-Ola-087120	Oryzias latipes	57.35	2.00e-67	248.00
IUUC-Olu-087648	Ostreococcus lucimarinus	26.70	2.00e-30	127.00
IUUC-Oga-088343	Otolemur garnettii	73.73	0.00e+00	2193.00
IUUC-Oar-089257	Ovis aries	73.73	0.00e+00	2224.00
IUUC-Ptr-090497	Pan troglodytes	73.87	0.00e+00	2178.00
IUUC-Pan-092638	Papio anubis	73.61	0.00e+00	2175.00
IUUC-Psi-093096	Pelodiscus sinensis	69.33	0.00e+00	1782.00
IUUC-Pma-094571	Petromyzon marinus	40.46	8.00e-82	297.00
IUUC-Pfo-096348	Poecilia formosa	62.39	0.00e+00	979.00
IUUC-Pab-098153	Pongo abelii	73.41	0.00e+00	2213.00
IUUC-Pca-100957	Procavia capensis	68.52	0.00e+00	2021.00
IUUC-Pva-102439	Pteropus vampyrus	74.17	0.00e+00	2239.00
IUUC-Rno-105891	Rattus norvegicus	70.87	0.00e+00	2038.00
IUUC-Sha-107181	Sarcophilus harrisii	92.55	0.00e+00	2644.00
IUUC-Ssc-115413	Sus scrofa	73.24	0.00e+00	2231.00
IUUC-Tgu-117082	Taeniopygia guttata	64.07	0.00e+00	1843.00
IUUC-Tru-118491	Takifugu rubripes	60.64	0.00e+00	970.00
IUUC-Tsy-119629	Tarsius syrichta	82.70	2.00e-148	521.00
IUUC-Tni-120240	Tetraodon nigroviridis	61.33	0.00e+00	964.00
IUUC-Tbe-127673	Tupaia belangeri	64.39	0.00e+00	1798.00
IUUC-Ttr-128562	Tursiops truncatus	70.87	0.00e+00	2128.00
IUUC-Vpa-130596	Vicugna pacos	73.88	0.00e+00	1630.00
IUUC-Xtr-132469	Xenopus tropicalis	57.36	0.00e+00	1696.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence