iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067765

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02018632

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000016836.2	ENSMLUT00000016846.2	ENSMLUP00000015354.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-43	144.8	636	667
UBD/Beta-Prp	1.20e-66	224.9	57	265

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWD 29
           gHt+++t+la+   +d++lvs+s+Dgt +vWD
   Q: 636  GHTAKITSLAWsphHDGRLVSASYDGTAQVWD 667
           8***********8766**************** PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcl 129
           + +l gh++ v+  +fs++     + +t+s+D+t+k+wd++t   v     h++++ +l++sp  +d +vsG++  ++ ++ l+ +   
   Q: 57   IGELVGHTERVSGFTFSHHPGqynLCATSSDDGTVKIWDVETKAVVAEHALHQHTISALHWSPrVKDLIVSGDEKGVVFCYWLNRNDSQ 145
           7899**************965677***************************************666**************966666666 PP
   S: 130  eetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvysls...........fdsng............. 192
           +  l ++ +++ c++ +p   +l++ G +D++v + d+ k g+++++l+g h+d ++s++           +                 
   Q: 146  H--LFIEPRTIFCLTCSPHHeDLVAIGYKDGIVVIIDIsKKGEVIHRLRG-HDDEIHSIAwcplpgedclpI---Nqeenseepelpng 228
           5..899999999999999999*****************999********9.*********666666666552...04556788888999 PP
   S: 193  ...........kelvsgsldgtvklwdlqtgecvrtl 218
                       +l++gs+d+t+++w++++g+ v+tl
   Q: 229  kviaqtpvtkgCYLATGSKDQTIRIWSCSRGRGVMTL 265
           99999999999********************999987 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MGQEPRTLPP SPNWYCARCS DAVPGGLFGF AARTSVFLVR VGPGAGAIPG TPPFRVIGEL 60
VGHTERVSGF TFSHHPGQYN LCATSSDDGT VKIWDVETKA VVAEHALHQH TISALHWSPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCCAGG AGCCGCGCAC GCTGCCGCCC TCCCCCAACT GGTACTGCGC CCGCTGCAGC 60
GATGCGGTCC CCGGGGGCCT CTTCGGGTTC GCGGCGCGGA CCTCCGTCTT CCTTGTCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	90.25	0.00e+00	2665.00
IUUC-Apl-003586	Anas platyrhynchos	62.07	0.00e+00	1629.00
IUUC-Aca-004956	Anolis carolinensis	62.43	0.00e+00	1866.00
IUUC-Ame-010753	Astyanax mexicanus	63.76	0.00e+00	1014.00
IUUC-Bta-012315	Bos taurus	88.54	0.00e+00	2640.00
IUUC-Cja-019334	Callithrix jacchus	87.41	0.00e+00	2635.00
IUUC-Cfa-021254	Canis familiaris	89.97	0.00e+00	2718.00
IUUC-Cpo-021984	Cavia porcellus	80.62	0.00e+00	2318.00
IUUC-Csa-023650	Chlorocebus sabaeus	87.55	0.00e+00	2616.00
IUUC-Cho-024860	Choloepus hoffmanni	82.09	0.00e+00	2398.00
IUUC-Cin-025778	Ciona intestinalis	41.97	2.00e-162	566.00
IUUC-Csv-026313	Ciona savignyi	41.40	6.00e-168	584.00
IUUC-Dre-028096	Danio rerio	50.86	0.00e+00	1433.00
IUUC-Dno-029799	Dasypus novemcinctus	87.46	0.00e+00	2212.00
IUUC-Dor-030885	Dipodomys ordii	75.29	0.00e+00	1086.00
IUUC-Ete-032918	Echinops telfairi	80.67	0.00e+00	2395.00
IUUC-Eca-034144	Equus caballus	88.82	0.00e+00	2569.00
IUUC-Eeu-034843	Erinaceus europaeus	78.08	0.00e+00	1770.00
IUUC-Fca-035948	Felis catus	90.19	0.00e+00	2657.00
IUUC-Fal-037303	Ficedula albicollis	61.25	0.00e+00	1789.00
IUUC-Gmo-039591	Gadus morhua	53.43	0.00e+00	849.00
IUUC-Gga-040570	Gallus gallus	62.28	0.00e+00	1621.00
IUUC-Gac-042646	Gasterosteus aculeatus	48.48	0.00e+00	1352.00
IUUC-Ggo-045605	Gorilla gorilla	80.07	0.00e+00	1813.00
IUUC-Hsa-046122	Homo sapiens	88.31	0.00e+00	2622.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	89.45	0.00e+00	2268.00
IUUC-Lch-050489	Latimeria chalumnae	57.23	0.00e+00	637.00
IUUC-Loc-052259	Lepisosteus oculatus	51.14	0.00e+00	1420.00
IUUC-Laf-053338	Loxodonta africana	86.75	0.00e+00	2592.00
IUUC-Mcc-055442	Macaca mulatta	87.55	0.00e+00	2614.00
IUUC-Meu-056245	Macropus eugenii	82.55	0.00e+00	863.00
IUUC-Mga-060202	Meleagris gallopavo	62.58	0.00e+00	1693.00
IUUC-Mmr-061730	Microcebus murinus	88.05	0.00e+00	2609.00
IUUC-Mdo-062880	Monodelphis domestica	73.26	0.00e+00	2179.00
IUUC-Mmu-063930	Mus musculus	80.75	0.00e+00	2328.00
IUUC-Mpu-066605	Mustela putorius furo	90.12	0.00e+00	2677.00
IUUC-Nle-069183	Nomascus leucogenys	87.85	0.00e+00	2592.00
IUUC-Opr-070659	Ochotona princeps	74.33	0.00e+00	1160.00
IUUC-Ont-072356	Oreochromis niloticus	62.31	0.00e+00	1014.00
IUUC-Oan-073056	Ornithorhynchus anatinus	70.04	0.00e+00	1974.00
IUUC-Ocu-073881	Oryctolagus cuniculus	85.53	0.00e+00	2617.00
IUUC-Ola-087120	Oryzias latipes	57.00	2.00e-66	244.00
IUUC-Olu-087648	Ostreococcus lucimarinus	25.62	2.00e-33	138.00
IUUC-Oga-088343	Otolemur garnettii	87.92	0.00e+00	2622.00
IUUC-Oar-089257	Ovis aries	88.93	0.00e+00	2666.00
IUUC-Ptr-090497	Pan troglodytes	88.31	0.00e+00	2597.00
IUUC-Pan-092638	Papio anubis	87.29	0.00e+00	2612.00
IUUC-Psi-093096	Pelodiscus sinensis	64.30	0.00e+00	1616.00
IUUC-Pma-094571	Petromyzon marinus	43.40	7.00e-85	307.00
IUUC-Pfo-096348	Poecilia formosa	61.59	0.00e+00	973.00
IUUC-Pab-098153	Pongo abelii	88.18	0.00e+00	2650.00
IUUC-Pca-100957	Procavia capensis	80.34	0.00e+00	2367.00
IUUC-Pva-102439	Pteropus vampyrus	92.08	0.00e+00	2738.00
IUUC-Rno-105891	Rattus norvegicus	81.93	0.00e+00	2321.00
IUUC-Sha-107181	Sarcophilus harrisii	72.69	0.00e+00	2058.00
IUUC-Ssc-115413	Sus scrofa	89.78	0.00e+00	2713.00
IUUC-Tgu-117082	Taeniopygia guttata	62.57	0.00e+00	1762.00
IUUC-Tru-118491	Takifugu rubripes	59.80	0.00e+00	958.00
IUUC-Tsy-119629	Tarsius syrichta	94.81	4.00e-169	589.00
IUUC-Tni-120240	Tetraodon nigroviridis	60.14	0.00e+00	956.00
IUUC-Tbe-127673	Tupaia belangeri	76.06	0.00e+00	2106.00
IUUC-Ttr-128562	Tursiops truncatus	86.67	0.00e+00	2588.00
IUUC-Vpa-130596	Vicugna pacos	84.02	0.00e+00	1857.00
IUUC-Xtr-132469	Xenopus tropicalis	56.08	0.00e+00	1600.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence