iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093096

Ensembl Protein ID

ENSPSIP00000004136.1

UniProt Accession

K7F7X6; K7F7X6_PELSI

Genbank Protein ID

ENSPSIP00000004136

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01197043

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000003898.1	ENSPSIT00000004159.1	ENSPSIP00000004136.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-28	96.6	410	445
UBD/Beta-Prp	3.00e-41	141.6	313	487

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtg 33
           gHt+++t+l++  +  ++lvs+++Dgt +vWD+ + 
   Q: 410  GHTAKITSLSWspHHeGRLVSACYDGTAQVWDVLKE 445
           8***********733699**************8665 PP

UBD/Beta-Prp

   S: 14   tcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk.......ilvtgseDrtikvwdls............t 83
           t + ++pd+++la g +dg+i+++++ + kll ++++h + ++a++++++         ++++gs  ++i+v +l+             
   Q: 313  TEISWKPDGKFLALGNEDGSIEIFQAPNLKLLCTIQQHHKLINAIRWHHEHGtqpelsyMIASGSINAVIYVHNLKsiiespsktpvtI 401
           678899*******************************************988999***9**************9999999999999988 PP
   S: 84   gkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlkt 168
            ++++tl gh+++++sls+sp    +lvs+  d t++vwd+ +++ l    +gh+g   cv+++p + + + +G++D +v  W  + 
   Q: 402  TEPFRTLVGHTAKITSLSWSPhHEGRLVSACYDGTAQVWDVLKEEPLC-NYRGHRGRLLCVQWSPVDpDSVYTGADDFCVHKWLTSK 487
           899******************555***********************9.9*******************************997644 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MQEAALMKGC YLASGSKDQT IRIWSCARGR GVMTLKLPTL KRRSGGIDPA IKERIWLTVH 60
WPCGHPTEIV SSCFGGELLL WDLSQSGKRK WTLLGSSSEG QNHTRIVFNL CSVQALGREL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATACGATCT CAGCATTGCA TTGGTCATCC CACGTGAAAG ATTTGGTGGT GTCCGGTGAT 60
GAGAAAGGGA TAGTCATTTG TTATTGGTAT AACAGAAACG ACAGCCAGCA GTTCTTCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	63.79	0.00e+00	1590.00
IUUC-Apl-003586	Anas platyrhynchos	73.99	0.00e+00	1929.00
IUUC-Aca-004956	Anolis carolinensis	67.51	0.00e+00	1737.00
IUUC-Ame-010753	Astyanax mexicanus	68.97	0.00e+00	780.00
IUUC-Bta-012315	Bos taurus	64.98	0.00e+00	1619.00
IUUC-Cja-019334	Callithrix jacchus	63.46	0.00e+00	1602.00
IUUC-Cfa-021254	Canis familiaris	64.50	0.00e+00	1640.00
IUUC-Cpo-021984	Cavia porcellus	62.26	0.00e+00	1523.00
IUUC-Csa-023650	Chlorocebus sabaeus	64.40	0.00e+00	1592.00
IUUC-Cho-024860	Choloepus hoffmanni	60.08	0.00e+00	1447.00
IUUC-Cin-025778	Ciona intestinalis	44.69	3.00e-119	422.00
IUUC-Csv-026313	Ciona savignyi	43.05	3.00e-122	432.00
IUUC-Dre-028096	Danio rerio	55.60	0.00e+00	1209.00
IUUC-Dno-029799	Dasypus novemcinctus	69.48	0.00e+00	1431.00
IUUC-Dor-030885	Dipodomys ordii	57.83	1.00e-128	454.00
IUUC-Ete-032918	Echinops telfairi	61.88	0.00e+00	1517.00
IUUC-Eca-034144	Equus caballus	64.95	0.00e+00	1615.00
IUUC-Eeu-034843	Erinaceus europaeus	62.71	0.00e+00	1420.00
IUUC-Fca-035948	Felis catus	64.99	0.00e+00	1597.00
IUUC-Fal-037303	Ficedula albicollis	72.96	0.00e+00	1857.00
IUUC-Gmo-039591	Gadus morhua	59.92	0.00e+00	649.00
IUUC-Gga-040570	Gallus gallus	74.03	0.00e+00	1938.00
IUUC-Gac-042646	Gasterosteus aculeatus	54.03	0.00e+00	1119.00
IUUC-Ggo-045605	Gorilla gorilla	64.01	0.00e+00	1181.00
IUUC-Hsa-046122	Homo sapiens	64.37	0.00e+00	1594.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	69.17	0.00e+00	1444.00
IUUC-Lch-050489	Latimeria chalumnae	58.70	0.00e+00	680.00
IUUC-Loc-052259	Lepisosteus oculatus	67.68	0.00e+00	726.00
IUUC-Laf-053338	Loxodonta africana	64.88	0.00e+00	1612.00
IUUC-Mcc-055442	Macaca mulatta	64.32	0.00e+00	1597.00
IUUC-Meu-056245	Macropus eugenii	61.60	0.00e+00	730.00
IUUC-Mga-060202	Meleagris gallopavo	71.49	0.00e+00	1839.00
IUUC-Mmr-061730	Microcebus murinus	64.09	0.00e+00	1594.00
IUUC-Mdo-062880	Monodelphis domestica	69.17	0.00e+00	1758.00
IUUC-Mmu-063930	Mus musculus	63.27	0.00e+00	1529.00
IUUC-Mpu-066605	Mustela putorius furo	64.22	0.00e+00	1608.00
IUUC-Mlu-067765	Myotis lucifugus	64.30	0.00e+00	1644.00
IUUC-Nle-069183	Nomascus leucogenys	64.12	0.00e+00	1553.00
IUUC-Opr-070659	Ochotona princeps	53.72	0.00e+00	799.00
IUUC-Ont-072356	Oreochromis niloticus	67.54	0.00e+00	771.00
IUUC-Oan-073056	Ornithorhynchus anatinus	67.64	0.00e+00	1707.00
IUUC-Ocu-073881	Oryctolagus cuniculus	64.67	0.00e+00	1670.00
IUUC-Olu-087648	Ostreococcus lucimarinus	26.00	2.00e-31	131.00
IUUC-Oga-088343	Otolemur garnettii	65.54	0.00e+00	1628.00
IUUC-Oar-089257	Ovis aries	65.62	0.00e+00	1644.00
IUUC-Ptr-090497	Pan troglodytes	64.07	0.00e+00	1590.00
IUUC-Pan-092638	Papio anubis	64.48	0.00e+00	1585.00
IUUC-Pma-094571	Petromyzon marinus	39.34	5.00e-76	278.00
IUUC-Pfo-096742	Poecilia formosa	48.79	0.00e+00	1179.00
IUUC-Pab-098153	Pongo abelii	64.01	0.00e+00	1600.00
IUUC-Pca-100957	Procavia capensis	62.40	0.00e+00	1471.00
IUUC-Pva-102439	Pteropus vampyrus	65.14	0.00e+00	1648.00
IUUC-Rno-105891	Rattus norvegicus	62.90	0.00e+00	1506.00
IUUC-Sha-107181	Sarcophilus harrisii	69.11	0.00e+00	1728.00
IUUC-Ssc-115413	Sus scrofa	64.15	0.00e+00	1621.00
IUUC-Tgu-117082	Taeniopygia guttata	72.41	0.00e+00	1809.00
IUUC-Tru-118491	Takifugu rubripes	66.67	0.00e+00	726.00
IUUC-Tsy-119629	Tarsius syrichta	75.11	9.00e-106	378.00
IUUC-Tni-120240	Tetraodon nigroviridis	66.33	0.00e+00	738.00
IUUC-Tbe-127673	Tupaia belangeri	56.20	0.00e+00	1297.00
IUUC-Ttr-128562	Tursiops truncatus	60.73	0.00e+00	1502.00
IUUC-Vpa-130596	Vicugna pacos	68.05	0.00e+00	1180.00
IUUC-Xtr-132469	Xenopus tropicalis	57.67	0.00e+00	1421.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence