iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088936

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03046245

Gene Name

OTUB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000005837.2	ENSOGAT00000005840.2	ENSOGAP00000005222.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/OTU	1.40e-48	164.8	41	230

Active Site

Position(s)	Description	Evidence
48	N/A	{ECO:0000256\|PIRSR:PIRSR013503-1}
51	Nucleophile	{ECO:0000256\|PIRSR:PIRSR013503-1}
224		{ECO:0000256\|PIRSR:PIRSR013503-1}

Domain Profile

DUB/OTU

   S: 2    lilktkgDGnCLlrAvsqs..........................................................llgvfdddslsd 32
           +i+ktkgDGnC++rA++++                                                          ll+vf+d+s+sd
   Q: 41   AIRKTKGDGNCFYRALGYAylesllgkgretlkfkervlqtpndllaagfeehkfrnffnafysvvelvekdgsvssLLKVFNDQSTSD 129
           79*************************************************************************************** PP
   S: 33   alveaLreltseylqkesdffsefieekedekefcqklvepeak.geeihifaLaqiLsrpiivvdvdsleskvggillpllfpeeklk 120
            +v++Lr+lts+++++++dff++fi+e++d+k+fc+++vep+a  +++i+i+aL+q+Ls++++v++vd++++    +l++++fpe++ +
   Q: 130  RIVQFLRLLTSAFIRNRADFFRHFIDEEMDIKDFCTHEVEPMAMeCDHIQITALSQALSIALQVEYVDEMDT----ALNHHVFPEAA-T 213
           **********************************************************************95....***********.* PP
   S: 121  kpivLlYrsgHYdaLva 137
           ++++LlY+++HY++L+a
   Q: 214  PSVYLLYKTSHYNILYA 230
           ***************97 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

QSETSFSLIS EKCDILSILR DHPENRIYQR KIQELSKRFT AIRKTKGDGN CFYRALGYAY 60
LESLLGKGRE TLKFKERVLQ TPNDLLAAGF EEHKFRNFFN AFYSVVELVE KDGSVSSLLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGAGTGAAA CATCTTTCAG CTTAATATCA GAAAAATGTG ACATTCTCTC AATTCTTCGG 60
GATCATCCTG AAAACAGGAT TTACCAAAGG AAAATCCAGG TGGGGCAGAG GGAAAAGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003323--OTU_dom
IPR030299--OTUB2
IPR016615--Otubain
IPR019400--Peptidase_C65_otubain

PROSITE

PS50802--OTU

Pfam

PF10275--Peptidase_C65

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002059	Ailuropoda melanoleuca	95.71	6.00e-133	466.00
IUUC-Bta-012766	Bos taurus	96.14	8.00e-133	465.00
IUUC-Cja-019480	Callithrix jacchus	94.42	9.00e-131	458.00
IUUC-Cfa-021106	Canis familiaris	96.14	1.00e-133	468.00
IUUC-Cpo-022187	Cavia porcellus	94.87	3.00e-132	463.00
IUUC-Csa-023493	Chlorocebus sabaeus	95.73	1.00e-132	464.00
IUUC-Cho-024411	Choloepus hoffmanni	76.59	9.00e-86	308.00
IUUC-Dno-029346	Dasypus novemcinctus	95.69	3.00e-132	464.00
IUUC-Dor-031012	Dipodomys ordii	96.14	1.00e-133	468.00
IUUC-Ete-032266	Echinops telfairi	87.07	2.00e-119	421.00
IUUC-Eca-033356	Equus caballus	96.57	5.00e-133	466.00
IUUC-Eeu-034775	Erinaceus europaeus	96.12	1.00e-132	465.00
IUUC-Fca-035363	Felis catus	95.28	3.00e-132	463.00
IUUC-Ggo-045023	Gorilla gorilla	95.28	1.00e-131	461.00
IUUC-Hsa-046984	Homo sapiens	95.71	4.00e-132	463.00
IUUC-Itr-048012	Ictidomys tridecemlineatus	95.71	9.00e-133	465.00
IUUC-Lch-050514	Latimeria chalumnae	61.78	1.00e-83	302.00
IUUC-Loc-052003	Lepisosteus oculatus	51.10	3.00e-65	241.00
IUUC-Laf-054382	Loxodonta africana	94.85	5.00e-132	462.00
IUUC-Mcc-055516	Macaca mulatta	95.30	2.00e-132	464.00
IUUC-Meu-056038	Macropus eugenii	87.83	6.00e-99	352.00
IUUC-Mmr-060918	Microcebus murinus	97.00	2.00e-134	471.00
IUUC-Mdo-062638	Monodelphis domestica	88.79	2.00e-123	434.00
IUUC-Mmu-063973	Mus musculus	95.30	5.00e-133	467.00
IUUC-Mpu-066013	Mustela putorius furo	96.12	1.00e-132	465.00
IUUC-Mlu-067509	Myotis lucifugus	95.71	3.00e-131	460.00
IUUC-Nle-069673	Nomascus leucogenys	95.71	4.00e-132	463.00
IUUC-Opr-070761	Ochotona princeps	88.48	5.00e-82	296.00
IUUC-Oan-072922	Ornithorhynchus anatinus	82.10	3.00e-112	397.00
IUUC-Ocu-074643	Oryctolagus cuniculus	96.14	2.00e-133	468.00
IUUC-Oni-082026	Oryza nivara	28.32	3.00e-15	76.30
IUUC-Oru-084761	Oryza rufipogon	28.32	3.00e-15	76.30
IUUC-Ola-086603	Oryzias latipes	45.83	6.00e-52	197.00
IUUC-Oar-089460	Ovis aries	96.58	2.00e-133	467.00
IUUC-Ptr-090805	Pan troglodytes	95.28	9.00e-132	462.00
IUUC-Pan-091969	Papio anubis	95.71	4.00e-132	463.00
IUUC-Pab-098476	Pongo abelii	95.30	4.00e-132	463.00
IUUC-Pca-100252	Procavia capensis	93.00	3.00e-53	201.00
IUUC-Pva-102204	Pteropus vampyrus	94.85	2.00e-132	464.00
IUUC-Pgr-103552	Puccinia graminis	75.00	2.50e-02	31.60
IUUC-Rno-105062	Rattus norvegicus	96.14	4.00e-134	469.00
IUUC-Sha-106968	Sarcophilus harrisii	88.70	2.00e-122	431.00
IUUC-Sar-113295	Sorex araneus	95.69	1.00e-130	458.00
IUUC-Ssc-115288	Sus scrofa	95.69	6.00e-132	462.00
IUUC-Tni-120440	Tetraodon nigroviridis	39.83	4.00e-43	167.00
IUUC-Tbe-127717	Tupaia belangeri	94.59	2.00e-78	283.00
IUUC-Ttr-128221	Tursiops truncatus	76.72	5.00e-100	356.00
IUUC-Uma-129443	Ustilago maydis	34.55	8.00e-25	107.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence