iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025134

UUCD1 version

UUC-CiI-00304

Ensembl Protein ID

ENSCINP00000015600.3

UniProt Accession

F6X5W4; F6X5W4_CIOIN

Protein Name

Defective in cullin neddylation protein

Gene Name

LOC100186269

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000007607.3	ENSCINT00000015600.3	ENSCINP00000015600.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/DCUN1	52.24	9.00e-59	225.00	IUUC-Hsa-046288

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ciona intestinalis

Functional Description
(View)

Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Protein Sequence
(Fasta)

MGNKCPACLC GADRASEVKC GGSKKKRKTK KSESVLPTDL HSSGAQKNLT GETGNRSQRP 60
DCLSLPTQQN NTKETKFPDF SLHGVQKSSP PSSSTTPIQS SKDHPYDPAN VEMLFRMYKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATAACTTA GACTTTATAT TCATATTGTA ATGTATTGAA TCCAACATGG GCAACAAGTG 60
TCCAGCGTGC TTATGTGGTG CAGATCGTGC AAGTGAGGTG AAGTGTGGTG GAAGTAAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation
GO:0009314--P:response to radiation

KEGG

cin:100186269

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001689	Ailuropoda melanoleuca	44.27	1.00e-60	225.00
IUUC-Apl-003497	Anas platyrhynchos	58.56	7.00e-61	226.00
IUUC-Aca-004961	Anolis carolinensis	48.15	1.00e-62	231.00
IUUC-Afu-009005	Aspergillus fumigatus	30.05	4.00e-16	76.30
IUUC-Ame-011413	Astyanax mexicanus	55.91	8.00e-60	222.00
IUUC-Bta-013338	Bos taurus	48.90	2.00e-60	224.00
IUUC-Cja-019458	Callithrix jacchus	55.91	2.00e-60	224.00
IUUC-Cfa-020160	Canis familiaris	48.90	1.00e-60	224.00
IUUC-Cpo-021835	Cavia porcellus	55.61	3.00e-60	223.00
IUUC-Csa-023328	Chlorocebus sabaeus	55.91	2.00e-60	224.00
IUUC-Cho-024888	Choloepus hoffmanni	49.12	2.00e-60	224.00
IUUC-Csv-025904	Ciona savignyi	74.79	1.00e-52	196.00
IUUC-Dre-027780	Danio rerio	54.30	5.00e-57	213.00
IUUC-Dno-028866	Dasypus novemcinctus	49.55	1.00e-60	225.00
IUUC-Dor-030387	Dipodomys ordii	57.07	3.00e-60	223.00
IUUC-Dme-032081	Drosophila melanogaster	44.73	4.00e-49	187.00
IUUC-Eca-033857	Equus caballus	45.45	7.00e-61	225.00
IUUC-Eeu-034825	Erinaceus europaeus	41.67	2.00e-46	177.00
IUUC-Fca-036130	Felis catus	55.91	2.00e-60	224.00
IUUC-Fal-037296	Ficedula albicollis	57.46	7.00e-60	222.00
IUUC-Gmo-039626	Gadus morhua	55.85	6.00e-60	222.00
IUUC-Gga-040741	Gallus gallus	58.01	2.00e-60	224.00
IUUC-Gac-042271	Gasterosteus aculeatus	58.89	1.00e-59	221.00
IUUC-Ggo-044727	Gorilla gorilla	55.91	2.00e-60	224.00
IUUC-Hsa-046288	Homo sapiens	55.91	1.00e-60	224.00
IUUC-Itr-049054	Ictidomys tridecemlineatus	55.61	2.00e-60	224.00
IUUC-Kpa-049127	Komagataella pastoris	36.02	2.00e-24	104.00
IUUC-Lch-050289	Latimeria chalumnae	52.88	1.00e-61	228.00
IUUC-Loc-052455	Lepisosteus oculatus	51.79	2.00e-55	207.00
IUUC-Laf-054369	Loxodonta africana	48.46	1.00e-59	221.00
IUUC-Mcc-055413	Macaca mulatta	42.70	2.00e-38	150.00
IUUC-Meu-056535	Macropus eugenii	48.97	1.00e-62	231.00
IUUC-Mga-059290	Meleagris gallopavo	58.01	1.00e-60	224.00
IUUC-Mmr-060689	Microcebus murinus	55.91	1.00e-60	224.00
IUUC-Mdo-062128	Monodelphis domestica	50.66	1.00e-60	225.00
IUUC-Mmu-064396	Mus musculus	55.61	1.00e-60	225.00
IUUC-Mpu-065926	Mustela putorius furo	44.27	1.00e-60	225.00
IUUC-Mlu-067044	Myotis lucifugus	49.12	4.00e-61	226.00
IUUC-Nfi-068610	Neosartorya fischeri	29.63	2.00e-16	77.40
IUUC-Nle-069346	Nomascus leucogenys	55.91	2.00e-60	224.00
IUUC-Opr-070682	Ochotona princeps	55.91	4.00e-60	223.00
IUUC-Ont-071772	Oreochromis niloticus	58.15	5.00e-60	223.00
IUUC-Oan-072765	Ornithorhynchus anatinus	58.15	3.00e-61	226.00
IUUC-Ocu-074272	Oryctolagus cuniculus	54.40	1.00e-59	221.00
IUUC-Ola-087561	Oryzias latipes	59.36	9.00e-63	232.00
IUUC-Oga-088440	Otolemur garnettii	51.61	1.00e-52	198.00
IUUC-Oar-089403	Ovis aries	48.90	1.00e-60	225.00
IUUC-Ptr-091384	Pan troglodytes	55.91	2.00e-60	224.00
IUUC-Pan-092650	Papio anubis	55.91	2.00e-60	224.00
IUUC-Psi-093806	Pelodiscus sinensis	58.15	5.00e-61	226.00
IUUC-Pma-094196	Petromyzon marinus	51.78	8.00e-63	232.00
IUUC-Pfo-096584	Poecilia formosa	57.98	5.00e-62	229.00
IUUC-Pab-098605	Pongo abelii	55.91	2.00e-60	224.00
IUUC-Pva-102172	Pteropus vampyrus	48.25	1.00e-59	221.00
IUUC-Ptt-103979	Puccinia triticina	28.12	3.00e-04	38.10
IUUC-Rno-105406	Rattus norvegicus	55.61	1.00e-60	225.00
IUUC-Sha-106531	Sarcophilus harrisii	48.97	1.00e-62	231.00
IUUC-Sar-113051	Sorex araneus	49.48	4.00e-50	189.00
IUUC-Ssc-115555	Sus scrofa	48.90	1.00e-60	225.00
IUUC-Tgu-117178	Taeniopygia guttata	57.46	7.00e-60	222.00
IUUC-Tru-117876	Takifugu rubripes	57.22	2.00e-62	230.00
IUUC-Tsy-118790	Tarsius syrichta	55.43	2.00e-58	217.00
IUUC-Tni-119673	Tetraodon nigroviridis	56.32	6.00e-61	226.00
IUUC-Tbe-127429	Tupaia belangeri	55.91	2.00e-60	224.00
IUUC-Ttr-128467	Tursiops truncatus	48.90	1.00e-60	225.00
IUUC-Xtr-132134	Xenopus tropicalis	50.91	6.00e-61	226.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence