iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072765

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Genbank Nucleotide ID

AAPN01430350

Gene Name

DCUN1D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000014290.2	ENSOANT00000022525.2	ENSOANP00000022521.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	6.70e-83	277.6	88	277

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 3    kkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkde 91
            +++eelf+rYkd++ed+i++eg+e+fc+dl+vdp++++vLvlawk++aat+c+f+r+ef++g+ a+++dsi+++++++++l +e+k+e
   Q: 88   GQRMEELFRRYKDEREDAILEEGMERFCNDLCVDPTEFKVLVLAWKFQAATMCKFTRKEFFEGCRAISADSIDGICARFPSLLNEAKQE 176
           689************************************************************************************** PP
   S: 92   qkfkdiYrfafnfakd..kgqksldldtaialwkLllaerefklldawlkfLeee..kkksiskDtWnllLefskviakdlsnYdeega 176
           ++fkd+Yrf+f+f++d  +gq+sl++++aialwkL+++++ +++ld+wl+fL+e+  + k+is+DtWn++L+f++vi +dlsnY+e++a
   Q: 177  DRFKDLYRFTFQFGLDseEGQRSLHREIAIALWKLVFTQNSPPILDQWLNFLSENpsGVKGISRDTWNMFLNFTQVIGPDLSNYSEDEA 265
           **************998899**********************************98899****************************** PP
   S: 177  WPvliDefveyl 188
           WP+l+D+fve++
   Q: 266  WPSLFDTFVEWE 277
           ***********7 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MGQCVTKCKN PSSTLGSKNG DRDPGSKSHS KRSAGPRDDH SPAGGKSAGD ILVNGTKKAE 60
AATESGRLPT SSGEAGKEPG QSAQESSGQR MEELFRRYKD EREDAILEEG MERFCNDLCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCTTGTCC CGTGTGGGGC TCACAGGCTC TATCCCCATT TTACAGGTGA GGAAACTGAG 60
ACCCCGAGAA GCCGAGTGAG TTGCCCAAGT TTGCACGGCA GACAAGTGGC GGAGCCGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0005737--C:cytoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0030308--P:negative regulation of cell growth
GO:0043065--P:positive regulation of apoptotic process
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation
GO:0010332--P:response to gamma radiation
GO:0009314--P:response to radiation
GO:0010225--P:response to UV-C

KEGG

oaa:100076976

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001689	Ailuropoda melanoleuca	85.20	2.00e-148	517.00
IUUC-Apl-003497	Anas platyrhynchos	84.21	2.00e-143	500.00
IUUC-Aca-004961	Anolis carolinensis	85.14	9.00e-143	498.00
IUUC-Aor-009902	Aspergillus oryzae	34.38	2.00e-11	60.50
IUUC-Ame-011413	Astyanax mexicanus	67.39	6.00e-103	366.00
IUUC-Bta-013338	Bos taurus	83.88	1.00e-146	511.00
IUUC-Cja-019458	Callithrix jacchus	83.55	3.00e-146	509.00
IUUC-Cfa-020160	Canis familiaris	84.87	8.00e-148	515.00
IUUC-Cpo-021835	Cavia porcellus	82.89	7.00e-136	475.00
IUUC-Csa-023328	Chlorocebus sabaeus	83.88	8.00e-147	511.00
IUUC-Cho-024888	Choloepus hoffmanni	87.32	7.00e-146	508.00
IUUC-Cin-025134	Ciona intestinalis	57.53	5.00e-61	227.00
IUUC-Csv-025904	Ciona savignyi	52.85	1.00e-33	133.00
IUUC-Dre-027780	Danio rerio	64.52	9.00e-98	348.00
IUUC-Dno-028866	Dasypus novemcinctus	87.68	2.00e-145	507.00
IUUC-Dor-030387	Dipodomys ordii	83.55	4.00e-144	503.00
IUUC-Dme-032081	Drosophila melanogaster	46.73	1.00e-49	189.00
IUUC-Eca-033857	Equus caballus	84.21	6.00e-148	515.00
IUUC-Eeu-034825	Erinaceus europaeus	77.96	8.00e-131	458.00
IUUC-Fca-036130	Felis catus	84.54	1.00e-147	514.00
IUUC-Fal-037296	Ficedula albicollis	83.88	1.00e-142	498.00
IUUC-Gmo-039626	Gadus morhua	64.44	3.00e-96	343.00
IUUC-Gga-040741	Gallus gallus	84.21	1.00e-141	494.00
IUUC-Gac-042271	Gasterosteus aculeatus	64.26	2.00e-94	338.00
IUUC-Ggo-044727	Gorilla gorilla	83.88	8.00e-147	511.00
IUUC-Hsa-046288	Homo sapiens	83.55	3.00e-146	510.00
IUUC-Itr-049054	Ictidomys tridecemlineatus	83.55	4.00e-146	509.00
IUUC-Lch-050289	Latimeria chalumnae	77.23	1.00e-126	444.00
IUUC-Loc-052455	Lepisosteus oculatus	70.50	2.00e-105	374.00
IUUC-Laf-054369	Loxodonta africana	82.57	2.00e-138	484.00
IUUC-Mcc-055413	Macaca mulatta	68.35	5.00e-101	359.00
IUUC-Meu-056535	Macropus eugenii	85.53	3.00e-143	500.00
IUUC-Mga-059290	Meleagris gallopavo	84.21	1.00e-142	498.00
IUUC-Mmr-060689	Microcebus murinus	83.55	4.00e-146	509.00
IUUC-Mdo-062128	Monodelphis domestica	85.86	4.00e-144	503.00
IUUC-Mmu-064396	Mus musculus	83.88	3.00e-147	513.00
IUUC-Mpu-065926	Mustela putorius furo	85.20	2.00e-148	517.00
IUUC-Mlu-067044	Myotis lucifugus	84.21	1.00e-147	514.00
IUUC-Nle-069346	Nomascus leucogenys	83.88	8.00e-147	511.00
IUUC-Opr-070682	Ochotona princeps	83.55	6.00e-136	476.00
IUUC-Ont-071772	Oreochromis niloticus	68.10	1.00e-99	355.00
IUUC-Ocu-074272	Oryctolagus cuniculus	82.48	2.00e-109	387.00
IUUC-Ola-087561	Oryzias latipes	68.46	3.00e-101	360.00
IUUC-Oga-088440	Otolemur garnettii	70.44	8.00e-112	395.00
IUUC-Oar-089403	Ovis aries	84.54	6.00e-148	515.00
IUUC-Ptr-091384	Pan troglodytes	83.88	8.00e-147	511.00
IUUC-Pan-092650	Papio anubis	83.88	8.00e-147	511.00
IUUC-Psi-093806	Pelodiscus sinensis	82.89	1.00e-134	471.00
IUUC-Pma-094196	Petromyzon marinus	65.42	1.00e-82	299.00
IUUC-Pfo-096584	Poecilia formosa	69.64	4.00e-105	373.00
IUUC-Pab-098605	Pongo abelii	83.88	8.00e-147	511.00
IUUC-Pca-100933	Procavia capensis	68.75	5.00e-99	353.00
IUUC-Pva-102172	Pteropus vampyrus	87.32	5.00e-145	506.00
IUUC-Rno-105406	Rattus norvegicus	84.21	3.00e-147	513.00
IUUC-Sha-106531	Sarcophilus harrisii	84.87	5.00e-144	502.00
IUUC-Sar-113051	Sorex araneus	67.76	9.00e-103	365.00
IUUC-Ssc-115555	Sus scrofa	83.88	5.00e-147	512.00
IUUC-Tgu-117178	Taeniopygia guttata	83.88	5.00e-143	499.00
IUUC-Tru-117876	Takifugu rubripes	67.75	9.00e-101	358.00
IUUC-Tsy-118790	Tarsius syrichta	85.23	6.00e-122	429.00
IUUC-Tni-119673	Tetraodon nigroviridis	68.48	5.00e-101	360.00
IUUC-Tbe-127429	Tupaia belangeri	84.54	1.00e-147	514.00
IUUC-Ttr-128467	Tursiops truncatus	84.54	5.00e-148	516.00
IUUC-Vpa-130376	Vicugna pacos	60.73	4.00e-86	310.00
IUUC-Xtr-132134	Xenopus tropicalis	76.07	2.00e-122	431.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence