iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000055721.1	ENSRNOT00000086014.1	ENSRNOP00000068929.1
ENSRNOG00000055721.1	ENSRNOT00000086308.1	ENSRNOP00000071530.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.90e-06	27.7	277	318

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e +   d +++l C+H+fh++C+  w         + +CP C+
   Q: 277  CAVCIELYkpNDVVRILTCNHIFHKTCVDPW------LLEHRTCPMCK 318
           ****998877777******************......9999******6 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MGPPPGIGVY CRGGCGAARL LAWCFLLALS PHAPGSRGAE AVWTAYLNVS WRVPHPGVNR 60
TVWELSEEGV YGQDSPLEPV SGVLVPPDGP GALNACNPHT NFTVPTVWGS TVQVSWLALI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCGGGAGGT GAGATCAGTT ACCTGCCTGC AACTGAAATT TCAACCTTCT GTTTAGAAGG 60
GACATGAGTG GACAATGGTG ACTGATAGTT GGAAGTATCT GCAGACATCT TAAGTTTTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0005794--C:Golgi apparatus
GO:0016021--C:integral component of membrane
GO:0005770--C:late endosome
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042036--P:negative regulation of cytokine biosynthetic process
GO:0031647--P:regulation of protein stability

KEGG

rno:315911

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000408	Aegilops tauschii	50.00	7.00e-13	67.00
IUUC-Aml-001674	Ailuropoda melanoleuca	95.82	0.00e+00	828.00
IUUC-Apl-003776	Anas platyrhynchos	67.22	6.00e-108	383.00
IUUC-Aca-004318	Anolis carolinensis	69.88	4.00e-119	421.00
IUUC-Afu-009087	Aspergillus fumigatus	32.33	4.00e-13	68.20
IUUC-Ame-011286	Astyanax mexicanus	46.40	5.00e-85	307.00
IUUC-Bta-013454	Bos taurus	93.97	0.00e+00	813.00
IUUC-Cja-019864	Callithrix jacchus	96.26	0.00e+00	830.00
IUUC-Cfa-020185	Canis familiaris	95.13	0.00e+00	818.00
IUUC-Csa-023224	Chlorocebus sabaeus	95.79	0.00e+00	800.00
IUUC-Cho-024710	Choloepus hoffmanni	79.54	4.00e-146	510.00
IUUC-Cne-026951	Cryptococcus neoformans	34.69	7.00e-11	61.60
IUUC-Dre-028249	Danio rerio	53.28	2.00e-89	322.00
IUUC-Dno-029216	Dasypus novemcinctus	94.83	5.00e-136	476.00
IUUC-Dor-030487	Dipodomys ordii	83.01	0.00e+00	668.00
IUUC-Dse-031357	Dothistroma septosporum	45.21	2.00e-12	67.00
IUUC-Ete-032376	Echinops telfairi	95.31	2.00e-137	481.00
IUUC-Eca-034264	Equus caballus	95.82	0.00e+00	828.00
IUUC-Eeu-034606	Erinaceus europaeus	91.73	9.00e-128	449.00
IUUC-Fca-036503	Felis catus	95.36	0.00e+00	821.00
IUUC-Fal-036671	Ficedula albicollis	60.59	2.00e-112	399.00
IUUC-Gmo-039483	Gadus morhua	47.65	1.00e-80	293.00
IUUC-Gga-040248	Gallus gallus	67.77	5.00e-134	470.00
IUUC-Hsa-046745	Homo sapiens	95.33	0.00e+00	822.00
IUUC-Itr-048362	Ictidomys tridecemlineatus	96.50	0.00e+00	837.00
IUUC-Lch-050549	Latimeria chalumnae	57.57	2.00e-121	429.00
IUUC-Loc-051929	Lepisosteus oculatus	56.51	3.00e-96	345.00
IUUC-Laf-054197	Loxodonta africana	93.97	0.00e+00	787.00
IUUC-Mcc-055146	Macaca mulatta	96.26	0.00e+00	805.00
IUUC-Meu-056649	Macropus eugenii	76.47	6.00e-165	573.00
IUUC-Mga-059520	Meleagris gallopavo	67.49	4.00e-134	471.00
IUUC-Mmr-061502	Microcebus murinus	95.56	0.00e+00	802.00
IUUC-Mdo-062875	Monodelphis domestica	67.11	6.00e-125	440.00
IUUC-Mmu-064235	Mus musculus	98.36	0.00e+00	846.00
IUUC-Mpu-066452	Mustela putorius furo	91.21	1.00e-170	592.00
IUUC-Mlu-067189	Myotis lucifugus	93.50	0.00e+00	791.00
IUUC-Nle-070026	Nomascus leucogenys	96.03	0.00e+00	805.00
IUUC-Opr-070435	Ochotona princeps	71.43	2.00e-95	342.00
IUUC-Oan-073238	Ornithorhynchus anatinus	77.35	2.00e-118	418.00
IUUC-Ocu-074960	Oryctolagus cuniculus	95.79	0.00e+00	796.00
IUUC-Ola-086348	Oryzias latipes	47.74	5.00e-78	284.00
IUUC-Oga-088543	Otolemur garnettii	92.99	0.00e+00	806.00
IUUC-Oar-089599	Ovis aries	93.97	0.00e+00	813.00
IUUC-Ptr-091576	Pan troglodytes	92.16	1.00e-168	585.00
IUUC-Pan-091690	Papio anubis	96.04	0.00e+00	800.00
IUUC-Psi-093642	Pelodiscus sinensis	77.90	1.00e-106	379.00
IUUC-Pfo-096270	Poecilia formosa	46.28	2.00e-77	282.00
IUUC-Pab-097965	Pongo abelii	95.56	0.00e+00	799.00
IUUC-Pva-102991	Pteropus vampyrus	84.50	1.00e-175	608.00
IUUC-Sha-107293	Sarcophilus harrisii	77.48	1.00e-156	545.00
IUUC-Ssl-108451	Sclerotinia sclerotiorum	54.00	1.00e-12	67.80
IUUC-Sar-113682	Sorex araneus	95.86	6.00e-144	503.00
IUUC-Ssc-115583	Sus scrofa	94.90	0.00e+00	815.00
IUUC-Tgu-117406	Taeniopygia guttata	58.71	5.00e-82	296.00
IUUC-Tru-118147	Takifugu rubripes	46.41	4.00e-74	271.00
IUUC-Tsy-118918	Tarsius syrichta	94.63	0.00e+00	769.00
IUUC-Tni-120865	Tetraodon nigroviridis	46.47	3.00e-69	255.00
IUUC-Ttr-128640	Tursiops truncatus	95.36	0.00e+00	791.00
IUUC-Vpa-130536	Vicugna pacos	87.04	0.00e+00	726.00
IUUC-Xma-133114	Xiphophorus maculatus	48.14	1.00e-78	286.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence