iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033595

UUCD1 version

UUC-EqC-01056

Ensembl Protein ID

ENSECAP00000009091.1

UniProt Accession

F6ZGZ9; F6ZGZ9_HORSE

Protein Name

Uncharacterized protein

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000011151.1	ENSECAT00000011612.1	ENSECAP00000009091.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.60e-87	292.0	24	726

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg..........ellkslqklfeel........w.... 61
           +Gl+NlgNtCY+NS+LQ+L+++p +++ +++      +kke+l++e+++ +kg          el++slq+l+ ++        +    
   Q: 24   VGLNNLGNTCYLNSILQVLYFCPGFKSGVKHlfniisRKKEALKDEANQRDKGnckedsltsyELICSLQSLIISVeqlqanflLnpek 112
           6***********************************999999999999888889999999999*********99996555555414555 PP
   S: 62   kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsde.... 129
           ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++                  e                  +    
   Q: 113  YTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLlkeeevknvaelstkveE------------------Kphqk 183
           88888*****************************************44433333333222222111..................13445 PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 184  gersginsvemdsmrhsedhkeklpkgngkrksdtefgnmkkkvkvskehqsleenqrqtrskrkatgdmleippkiipkyisegesar 272
           66777788888888*************************************************************************** PP
   S: 130  ...................................................................................aeekkk 135
                                                                                               +    
   Q: 273  psqkksrvkvnwlkpatkqpsilskfcslgkitthqgskeqskeseyleedlgkgenddttngcglespgndvksinvnevkpINTG-- 359
           **********************************************************************88888877544333333.. PP
   S: 136  kknk.....slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenk 205
                    +l+++lFqgql  +++clec++ ++r+e+f+d+s+pv+++e +k e              +l++++++f++ e++ ge+k
   Q: 360  ---AeqigfELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEesseispepktemkTLRWAISQFASVERIVGEDK 445
           ...256666*****************************************99998********************************** PP
   S: 206  yycekckkkqeaekklklkklPevLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG. 288
           y+ce+c++++eae++l ++k+Pev+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L+avv+HsG 
   Q: 446  YFCENCHHYTEAERSLLFDKMPEVITIHLKCFaasglEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPT-----NDSYGLFAVVMHSGi 529
           *******************************************************************99.....678************ PP
   S: 289  slssGHYvayvkn............................................................................ 301
           ++ssGHY+a vk                                                                             
   Q: 530  TISSGHYTASVKVtdlnsleldkgnfvvdqmceigkpepsneeeargvvenyadedvsirvgantqpskvlnkknveaigllggqkska 618
           ***************************************************************************************** PP
   S: 302  ..................................................................ekgkWllfdDskVtevkeeevle 324
                                                                              +gkWllfdDs+V++++e+++l+
   Q: 619  dyelynkasnpdkgastafaenrssetnssngthesdrnkessdqtginisgfenkisyvvqslkeYEGKWLLFDDSEVKVTEEKDFLN 707
           ******************************9999999999999999999999988888888877766999******************* PP
   S: 325  etg......staYvlfYkr 337
           + +      st+Y+lfYk+
   Q: 708  SLSpstsptSTPYLLFYKK 726
           888**************97 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

DQVVPAAQSS PINCEKRENL LPFVGLNNLG NTCYLNSILQ VLYFCPGFKS GVKHLFNIIS 60
RKKEALKDEA NQRDKGNCKE DSLTSYELIC SLQSLIISVE QLQANFLLNP EKYTDELATQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCAATAGTG ATCAAGTTGT TCCGGCAGCA CAGTCCTCAC CTATAAACTG TGAGAAGAGG 60
GAGAACTTGT TACCATTTGT GGGACTGAAT AATCTCGGCA ATACTTGTTA TCTTAATAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	92.59	0.00e+00	1304.00
IUUC-Apl-004204	Anas platyrhynchos	71.79	0.00e+00	926.00
IUUC-Aca-004637	Anolis carolinensis	64.17	0.00e+00	832.00
IUUC-Ame-011718	Astyanax mexicanus	48.03	3.00e-159	555.00
IUUC-Bta-012552	Bos taurus	90.25	0.00e+00	1278.00
IUUC-Cja-019588	Callithrix jacchus	93.82	0.00e+00	1351.00
IUUC-Cfa-020211	Canis familiaris	93.27	0.00e+00	1324.00
IUUC-Cpo-021551	Cavia porcellus	82.94	0.00e+00	1151.00
IUUC-Csa-024186	Chlorocebus sabaeus	93.68	0.00e+00	1354.00
IUUC-Cho-024739	Choloepus hoffmanni	80.59	0.00e+00	633.00
IUUC-Dre-028184	Danio rerio	48.57	1.00e-169	590.00
IUUC-Dno-029669	Dasypus novemcinctus	89.19	0.00e+00	1273.00
IUUC-Dor-030168	Dipodomys ordii	84.40	0.00e+00	1132.00
IUUC-Dme-031732	Drosophila melanogaster	29.25	1.00e-18	89.40
IUUC-Ete-032825	Echinops telfairi	85.42	0.00e+00	937.00
IUUC-Eeu-034877	Erinaceus europaeus	79.05	1.00e-159	556.00
IUUC-Fca-035381	Felis catus	92.98	0.00e+00	899.00
IUUC-Fal-037592	Ficedula albicollis	68.51	0.00e+00	877.00
IUUC-Gmo-039680	Gadus morhua	45.43	1.00e-150	526.00
IUUC-Gga-041196	Gallus gallus	70.71	0.00e+00	967.00
IUUC-Gac-042292	Gasterosteus aculeatus	58.15	2.00e-84	307.00
IUUC-Ggo-044671	Gorilla gorilla	93.82	0.00e+00	1357.00
IUUC-Hsa-047020	Homo sapiens	93.68	0.00e+00	1352.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	83.52	0.00e+00	1142.00
IUUC-Lch-050543	Latimeria chalumnae	57.69	0.00e+00	691.00
IUUC-Loc-052338	Lepisosteus oculatus	51.24	0.00e+00	650.00
IUUC-Laf-053707	Loxodonta africana	90.03	0.00e+00	1300.00
IUUC-Mcc-055885	Macaca mulatta	93.82	0.00e+00	1357.00
IUUC-Meu-056573	Macropus eugenii	72.44	0.00e+00	920.00
IUUC-Mga-059346	Meleagris gallopavo	72.20	0.00e+00	978.00
IUUC-Mmr-061612	Microcebus murinus	92.03	0.00e+00	1276.00
IUUC-Mdo-062887	Monodelphis domestica	74.15	0.00e+00	987.00
IUUC-Mmu-064044	Mus musculus	85.87	0.00e+00	1229.00
IUUC-Mpu-066847	Mustela putorius furo	93.68	0.00e+00	1323.00
IUUC-Mlu-067684	Myotis lucifugus	91.08	0.00e+00	1315.00
IUUC-Nle-070057	Nomascus leucogenys	93.54	0.00e+00	1355.00
IUUC-Opr-070463	Ochotona princeps	82.14	0.00e+00	1125.00
IUUC-Ont-071975	Oreochromis niloticus	51.05	5.00e-139	488.00
IUUC-Ocu-074840	Oryctolagus cuniculus	91.35	0.00e+00	1295.00
IUUC-Ola-087088	Oryzias latipes	46.17	9.00e-160	557.00
IUUC-Oga-088472	Otolemur garnettii	91.21	0.00e+00	1296.00
IUUC-Oar-089498	Ovis aries	90.25	0.00e+00	1282.00
IUUC-Ptr-091395	Pan troglodytes	93.96	0.00e+00	1355.00
IUUC-Pan-092462	Papio anubis	93.96	0.00e+00	1358.00
IUUC-Psi-093583	Pelodiscus sinensis	70.88	0.00e+00	895.00
IUUC-Pma-094644	Petromyzon marinus	41.18	7.00e-25	107.00
IUUC-Pfo-096314	Poecilia formosa	44.98	5.00e-154	538.00
IUUC-Pab-098568	Pongo abelii	94.51	0.00e+00	1365.00
IUUC-Pca-100948	Procavia capensis	80.00	0.00e+00	1121.00
IUUC-Pva-102853	Pteropus vampyrus	92.03	0.00e+00	1312.00
IUUC-Rno-105573	Rattus norvegicus	86.13	0.00e+00	1218.00
IUUC-Sha-107495	Sarcophilus harrisii	71.73	0.00e+00	881.00
IUUC-Sar-113545	Sorex araneus	76.54	0.00e+00	1023.00
IUUC-Ssc-115962	Sus scrofa	92.60	0.00e+00	1327.00
IUUC-Tgu-116731	Taeniopygia guttata	69.25	0.00e+00	896.00
IUUC-Tru-117893	Takifugu rubripes	46.11	7.00e-144	504.00
IUUC-Tsy-119644	Tarsius syrichta	82.28	0.00e+00	1127.00
IUUC-Tni-119819	Tetraodon nigroviridis	44.21	1.00e-153	536.00
IUUC-Tbe-127272	Tupaia belangeri	87.38	0.00e+00	1235.00
IUUC-Ttr-128404	Tursiops truncatus	92.17	0.00e+00	1319.00
IUUC-Vpa-130205	Vicugna pacos	91.76	0.00e+00	1310.00
IUUC-Xtr-132613	Xenopus tropicalis	55.87	0.00e+00	703.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence