iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062887

UUCD1 version

UUC-MoD-01143

Ensembl Protein ID

ENSMODP00000001843.2

UniProt Accession

F7F488; F7F488_MONDO

Protein Name

Uncharacterized protein

Gene Name

USP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000001514.2	ENSMODT00000001883.2	ENSMODP00000001843.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.50e-88	296.2	94	796

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle......kkkeklneenpkepkg...........ellkslqklfeel........w... 61
           +Gl+NlgNtCY+NS+LQ+L+++p ++  +++      kkke l++e +++ ++           el++slq+l+ ++        +   
   Q: 94   VGLNNLGNTCYLNSILQVLYFCPGFKTGVKHlfnvitKKKEILKDETNQKVEKgngkddnlasyELICSLQSLIISVeqlqanflLnpe 182
           6******************************9999984444444444433333566666778889********9999655555541455 PP
   S: 62   .kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.................... 129
            ++++ a++pr+ll++l++++++++gy q+DaqE+l+++l +++e+++  k+++ +++ +e +++ s                      
   Q: 183  kYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEELKNMPGELEEKPSPRegseinapdddgvassadgk 271
           588888*****************************************665555555554444444333367788899999********* PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 272  dkiskgngkrksdsevgnpkkkskltkeqtsseenqrqtrskrkatgdtarsesspeatpkcategdparptqkksrlklnwlkpttkq 360
           ***************************************************************************************** PP
   S: 130  .................................................................aeekkkkknkslisdlFqgqlksq 153
                                                                            +++  ++   +l+++lFqgql  +
   Q: 361  psilskfcslgkitthsgpkghsreaddgdheedfkceprsylkdesgepappgrsmedketqalRNKGMEQVCFELVEKLFQGQLVLR 449
           *******************************************************99877655444444444444************** PP
   S: 154  ikclecdnvssreepfldlslpvpgkeetkke..............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPe 228
           ++clec++ ++r+e+f+d+s+pv+++e +k e              sl++++++f++ e++ ge+ky+ce+c++++eae++l ++k+Pe
   Q: 450  TRCLECESLTERREDFQDISVPVQEEEFSKVEesseispepktelkSLKWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPE 538
           ***************************998889******************************************************** PP
   S: 229  vLilhLkRf.....sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.......... 301
           v+++hLk+f     +f+++++  +kin+ + +pl+L+l+++ t+p+     +++Y L+avv+HsG ++ssGHY+a vk           
   Q: 539  VITIHLKCFaatglEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPT-----NDSYGLFAVVMHSGiTISSGHYTASVKVtdlhsleldt 622
           ********************************************99.....678*********************************** PP
   S: 302  ......................................................................................... 301
                                                                                                    
   Q: 623  ehfmvdqtdemgkpdplgeeeakalaedyddevafrvsgssqaskvlnkknveavgllggqkskpdyefynshkaanpekvvgaaaesr 711
           ***************************************************************************************** PP
   S: 302  ...........................................ekgkWllfdDskVtevkeeevleetg......staYvlfYkr 337
                                                       +gkWllfdDs+V++++e+++l++ +      st+Y+lfYk+
   Q: 712  nsessstagaqeldrdkepsghmdahangpenkasyvlqslkeYEGKWLLFDDSEVKVTEEKDFLNSLSpatsstSTPYLLFYKK 796
           **********9999999999999999999988888888877766899*******************888**************97 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MPGVLPSESH GLLAARGSPK KSRLSLKFFQ KKETKRALDF TGDVQDDEDR GPPEAGGAGG 60
AAAPEVDQVV PATGVAQPSP LGTCDKRETL LPFVGLNNLG NTCYLNSILQ VLYFCPGFKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCAGCCGG TGACGGGGAA AGATGCCCGG GGTCCTGCCC AGTGAGAGCC ACGGGCTGCT 60
GGCGGCCAGG GGGAGCCCCA AGAAGAGCCG CCTATCTCTC AAGTTCTTCC AGAAGAAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033815--USP1
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0006282--P:regulation of DNA repair
GO:0009411--P:response to UV
GO:0001501--P:skeletal system development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mdo:100031700

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001939	Ailuropoda melanoleuca	73.45	0.00e+00	1099.00
IUUC-Apl-004204	Anas platyrhynchos	70.72	0.00e+00	922.00
IUUC-Aca-004637	Anolis carolinensis	62.45	0.00e+00	875.00
IUUC-Ame-011718	Astyanax mexicanus	48.12	0.00e+00	633.00
IUUC-Bta-012552	Bos taurus	72.67	0.00e+00	1080.00
IUUC-Cja-019588	Callithrix jacchus	73.11	0.00e+00	1096.00
IUUC-Cfa-020211	Canis familiaris	73.42	0.00e+00	1096.00
IUUC-Cpo-021551	Cavia porcellus	71.84	0.00e+00	1058.00
IUUC-Csa-024186	Chlorocebus sabaeus	73.30	0.00e+00	1108.00
IUUC-Cho-024739	Choloepus hoffmanni	62.60	3.00e-152	531.00
IUUC-Dre-028184	Danio rerio	50.18	1.00e-180	626.00
IUUC-Dno-029669	Dasypus novemcinctus	71.98	0.00e+00	1089.00
IUUC-Dor-030168	Dipodomys ordii	68.86	0.00e+00	959.00
IUUC-Dme-031732	Drosophila melanogaster	30.39	1.00e-18	89.00
IUUC-Ete-032825	Echinops telfairi	68.90	0.00e+00	727.00
IUUC-Eca-033595	Equus caballus	74.15	0.00e+00	1035.00
IUUC-Eeu-034877	Erinaceus europaeus	70.40	2.00e-123	436.00
IUUC-Fca-035381	Felis catus	72.19	0.00e+00	760.00
IUUC-Fal-037592	Ficedula albicollis	68.27	0.00e+00	932.00
IUUC-Gmo-039680	Gadus morhua	45.60	1.00e-157	550.00
IUUC-Gga-041196	Gallus gallus	68.42	0.00e+00	993.00
IUUC-Gac-042292	Gasterosteus aculeatus	48.83	1.00e-141	497.00
IUUC-Ggo-044671	Gorilla gorilla	73.98	0.00e+00	1113.00
IUUC-Hsa-047020	Homo sapiens	73.85	0.00e+00	1111.00
IUUC-Itr-048800	Ictidomys tridecemlineatus	66.25	0.00e+00	962.00
IUUC-Lch-050543	Latimeria chalumnae	57.76	0.00e+00	692.00
IUUC-Loc-052338	Lepisosteus oculatus	51.60	0.00e+00	705.00
IUUC-Laf-053707	Loxodonta africana	73.06	0.00e+00	1086.00
IUUC-Mcc-055885	Macaca mulatta	73.55	0.00e+00	1112.00
IUUC-Meu-056573	Macropus eugenii	81.98	0.00e+00	1051.00
IUUC-Mga-059346	Meleagris gallopavo	69.91	0.00e+00	962.00
IUUC-Mmr-061612	Microcebus murinus	72.42	0.00e+00	1063.00
IUUC-Mmu-064044	Mus musculus	72.28	0.00e+00	1097.00
IUUC-Mpu-066847	Mustela putorius furo	73.17	0.00e+00	1102.00
IUUC-Mlu-067684	Myotis lucifugus	72.80	0.00e+00	1092.00
IUUC-Nle-070057	Nomascus leucogenys	73.98	0.00e+00	1113.00
IUUC-Opr-070463	Ochotona princeps	73.18	0.00e+00	797.00
IUUC-Ont-071975	Oreochromis niloticus	52.28	4.00e-141	495.00
IUUC-Oan-073062	Ornithorhynchus anatinus	64.29	1.00e-29	122.00
IUUC-Ocu-074840	Oryctolagus cuniculus	73.11	0.00e+00	1080.00
IUUC-Ola-087088	Oryzias latipes	46.76	2.00e-172	599.00
IUUC-Oga-088472	Otolemur garnettii	72.93	0.00e+00	1073.00
IUUC-Oar-089498	Ovis aries	72.60	0.00e+00	1088.00
IUUC-Ptr-091395	Pan troglodytes	73.85	0.00e+00	1112.00
IUUC-Pan-092462	Papio anubis	73.42	0.00e+00	1112.00
IUUC-Psi-093583	Pelodiscus sinensis	70.50	0.00e+00	886.00
IUUC-Pma-094644	Petromyzon marinus	34.96	2.00e-25	108.00
IUUC-Pfo-096314	Poecilia formosa	46.93	7.00e-167	580.00
IUUC-Pab-098568	Pongo abelii	73.73	0.00e+00	1111.00
IUUC-Pca-100948	Procavia capensis	64.93	3.00e-144	505.00
IUUC-Pva-102853	Pteropus vampyrus	73.32	0.00e+00	1103.00
IUUC-Rno-105573	Rattus norvegicus	73.20	0.00e+00	1088.00
IUUC-Sha-107495	Sarcophilus harrisii	82.44	0.00e+00	1030.00
IUUC-Sar-113545	Sorex araneus	61.57	0.00e+00	834.00
IUUC-Ssc-115962	Sus scrofa	73.67	0.00e+00	1098.00
IUUC-Tgu-116731	Taeniopygia guttata	69.06	0.00e+00	950.00
IUUC-Tru-117893	Takifugu rubripes	46.45	2.00e-158	553.00
IUUC-Tsy-119644	Tarsius syrichta	81.09	2.00e-140	493.00
IUUC-Tni-119819	Tetraodon nigroviridis	46.55	3.00e-166	578.00
IUUC-Tbe-127272	Tupaia belangeri	70.47	0.00e+00	956.00
IUUC-Ttr-128404	Tursiops truncatus	71.82	0.00e+00	1073.00
IUUC-Vpa-130205	Vicugna pacos	72.99	0.00e+00	1089.00
IUUC-Xtr-132613	Xenopus tropicalis	53.07	0.00e+00	733.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence