iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093628

Ensembl Protein ID

ENSPSIP00000019315.1

UniProt Accession

K7GGA4; K7GGA4_PELSI

Genbank Protein ID

ENSPSIP00000019315

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01122772

Gene Name

SOCS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000017159.1	ENSPSIT00000019405.1	ENSPSIP00000019315.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	63.98	4.00e-73	271.00	IUUC-Hsa-046010

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MVAHSKVAAD NAVAADPRCR LDPPARDHSQ PRGYHGPARS NTVQAQSDTH FRTFRSQADF 60
SSITRASALL DACGFYWGPL SVSAAHEKLK SEPEGTFLLR DSRQKNCFFA ISVKTATGPT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGCGACTG CGGGTGCCAG CCCTAGGAGT GCACCACTGC GCGCGGGGGC CGGGAGCGCG 60
CTGCGCGGGT TGATGGCGCA GCGCTGATCC CCGCGGCCCA GGGCAGAGAA GGTAAGGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028411--SOCS1
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0000932--C:P-body
GO:0019210--F:kinase inhibitor activity
GO:0071230--P:cellular response to amino acid stimulus
GO:0019221--P:cytokine-mediated signaling pathway
GO:0045444--P:fat cell differentiation
GO:0007259--P:JAK-STAT cascade
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0016567--P:protein ubiquitination
GO:0010534--P:regulation of activation of JAK2 kinase activity
GO:0050707--P:regulation of cytokine secretion
GO:0060334--P:regulation of interferon-gamma-mediated signaling pathway

KEGG

pss:102443510

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001204	Ailuropoda melanoleuca	68.75	7.00e-63	232.00
IUUC-Apl-003313	Anas platyrhynchos	88.89	3.00e-103	366.00
IUUC-Aca-005109	Anolis carolinensis	68.99	1.00e-64	238.00
IUUC-Aly-006468	Arabidopsis lyrata	31.08	1.20e+00	27.70
IUUC-Ame-011550	Astyanax mexicanus	57.41	1.00e-54	205.00
IUUC-Bta-013411	Bos taurus	74.53	6.00e-73	266.00
IUUC-Cja-019595	Callithrix jacchus	75.16	2.00e-73	267.00
IUUC-Cfa-020563	Canis familiaris	73.91	2.00e-72	264.00
IUUC-Cpo-021374	Cavia porcellus	74.53	6.00e-73	266.00
IUUC-Csa-023333	Chlorocebus sabaeus	75.78	5.00e-74	270.00
IUUC-Dre-028507	Danio rerio	53.01	3.00e-47	181.00
IUUC-Dno-029406	Dasypus novemcinctus	75.78	4.00e-73	266.00
IUUC-Ete-032399	Echinops telfairi	73.91	7.00e-72	262.00
IUUC-Eca-033519	Equus caballus	73.12	4.00e-69	253.00
IUUC-Fal-036726	Ficedula albicollis	86.96	4.00e-94	336.00
IUUC-Gmo-039667	Gadus morhua	45.13	3.00e-24	104.00
IUUC-Gga-040970	Gallus gallus	87.44	5.00e-100	356.00
IUUC-Gac-041838	Gasterosteus aculeatus	44.25	1.00e-35	142.00
IUUC-Ggo-045569	Gorilla gorilla	75.62	1.00e-73	268.00
IUUC-Hsa-046010	Homo sapiens	75.16	2.00e-73	267.00
IUUC-Itr-047995	Ictidomys tridecemlineatus	75.16	3.00e-73	267.00
IUUC-Lch-050219	Latimeria chalumnae	70.19	9.00e-67	245.00
IUUC-Loc-052494	Lepisosteus oculatus	57.49	1.00e-64	238.00
IUUC-Laf-054219	Loxodonta africana	73.53	3.00e-57	213.00
IUUC-Mcc-054830	Macaca mulatta	75.78	5.00e-74	270.00
IUUC-Meu-056565	Macropus eugenii	76.53	1.00e-84	305.00
IUUC-Mga-060153	Meleagris gallopavo	86.96	1.00e-92	331.00
IUUC-Mmr-061365	Microcebus murinus	75.16	3.00e-73	267.00
IUUC-Mdo-062824	Monodelphis domestica	75.58	4.00e-84	303.00
IUUC-Mmu-064120	Mus musculus	72.67	1.00e-71	262.00
IUUC-Mpu-066839	Mustela putorius furo	75.16	2.00e-73	268.00
IUUC-Mlu-067829	Myotis lucifugus	73.29	8.00e-72	262.00
IUUC-Nle-069592	Nomascus leucogenys	73.29	1.00e-70	258.00
IUUC-Ont-072173	Oreochromis niloticus	48.12	4.00e-38	150.00
IUUC-Oan-073586	Ornithorhynchus anatinus	49.53	1.00e-24	105.00
IUUC-Ocu-073996	Oryctolagus cuniculus	73.91	2.00e-72	264.00
IUUC-Ola-087158	Oryzias latipes	50.00	2.00e-40	158.00
IUUC-Oga-088076	Otolemur garnettii	74.85	2.00e-73	268.00
IUUC-Ptr-091241	Pan troglodytes	75.16	2.00e-73	268.00
IUUC-Pan-091836	Papio anubis	76.25	4.00e-74	270.00
IUUC-Pfo-097501	Poecilia formosa	45.91	1.00e-36	145.00
IUUC-Pab-098170	Pongo abelii	75.16	2.00e-73	267.00
IUUC-Pop-100072	Populus trichocarpa	37.21	1.80e-02	33.10
IUUC-Pva-102796	Pteropus vampyrus	74.53	8.00e-73	266.00
IUUC-Rno-105319	Rattus norvegicus	72.67	1.00e-71	262.00
IUUC-Sha-107201	Sarcophilus harrisii	84.42	7.00e-77	278.00
IUUC-Ssc-116004	Sus scrofa	75.16	2.00e-73	267.00
IUUC-Tgu-116836	Taeniopygia guttata	86.47	1.00e-99	355.00
IUUC-Tru-118090	Takifugu rubripes	45.62	1.00e-36	145.00
IUUC-Tni-120719	Tetraodon nigroviridis	44.12	5.00e-32	130.00
IUUC-Vpa-130235	Vicugna pacos	75.16	2.00e-73	267.00
IUUC-Xtr-132610	Xenopus tropicalis	68.25	5.00e-75	273.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence