iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013527

Ensembl Protein ID

ENSBTAP00000023731.5

UniProt Accession

E1BIM5; E1BIM5_BOVIN

Genbank Protein ID

ENSBTAP00000023731

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02067751

Gene Name

ARHGEF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000017850.5	ENSBTAT00000023731.5	ENSBTAP00000023731.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.20e-14	52.8	164	218

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            v++ ++++ +n+deL+  kGd+++v     +++gW++g  +l+g+ G fP+n+v++++
   Q: 164  IVKARFNFKQTNEDELSVCKGDIIYVT--RVEEGGWWEG--TLNGRTGWFPSNYVREIK 218
           68999*********************7..999*******..8**************997 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MNPEERVVTW LISLGVLDSP KKTICDPEEF LKSSLKNGVV LCKLINRLRP GSVEKYCLEP 60
QTEADCTNNI NDFLKGCAAL QVEIFDPDDL YAGVNFSKVL NTLLAVNKAT EDQLSERPCG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCATTCAG TCTGCAGTAA TGAATCCAGA AGAGCGTGTC GTGACCTGGC TCATATCCTT 60
GGGAGTATTA GATTCCCCCA AAAAGACCAT CTGTGATCCT GAGGAGTTCT TGAAGTCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

KEGG

bta:533823

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001631	Ailuropoda melanoleuca	86.79	0.00e+00	1167.00
IUUC-Apl-003960	Anas platyrhynchos	75.39	0.00e+00	1129.00
IUUC-Aca-004988	Anolis carolinensis	70.31	0.00e+00	1038.00
IUUC-Ame-011546	Astyanax mexicanus	62.74	0.00e+00	941.00
IUUC-Cja-018935	Callithrix jacchus	94.07	0.00e+00	1380.00
IUUC-Cfa-021269	Canis familiaris	94.59	0.00e+00	1402.00
IUUC-Cpo-021620	Cavia porcellus	88.60	0.00e+00	1303.00
IUUC-Csa-023415	Chlorocebus sabaeus	94.46	0.00e+00	1387.00
IUUC-Dre-028580	Danio rerio	62.88	0.00e+00	958.00
IUUC-Dno-029201	Dasypus novemcinctus	89.63	0.00e+00	1362.00
IUUC-Dor-030868	Dipodomys ordii	75.26	0.00e+00	1021.00
IUUC-Eca-033500	Equus caballus	95.10	0.00e+00	1399.00
IUUC-Eeu-035269	Erinaceus europaeus	84.20	4.00e-169	588.00
IUUC-Fca-035683	Felis catus	94.20	0.00e+00	1375.00
IUUC-Fal-037611	Ficedula albicollis	74.87	0.00e+00	1120.00
IUUC-Gmo-038980	Gadus morhua	61.12	0.00e+00	910.00
IUUC-Gga-040940	Gallus gallus	73.62	0.00e+00	1115.00
IUUC-Gac-042203	Gasterosteus aculeatus	59.52	0.00e+00	928.00
IUUC-Ggo-044755	Gorilla gorilla	94.85	0.00e+00	1390.00
IUUC-Hsa-046210	Homo sapiens	94.59	0.00e+00	1387.00
IUUC-Lch-049517	Latimeria chalumnae	69.71	0.00e+00	1045.00
IUUC-Loc-052393	Lepisosteus oculatus	65.01	0.00e+00	1018.00
IUUC-Laf-054196	Loxodonta africana	91.48	0.00e+00	1328.00
IUUC-Mcc-055716	Macaca mulatta	94.46	0.00e+00	1387.00
IUUC-Meu-056285	Macropus eugenii	73.38	0.00e+00	682.00
IUUC-Mtr-058576	Medicago truncatula	45.45	5.00e-12	65.10
IUUC-Mga-060029	Meleagris gallopavo	75.26	0.00e+00	1134.00
IUUC-Mmr-060803	Microcebus murinus	93.56	0.00e+00	1376.00
IUUC-Mdo-062654	Monodelphis domestica	80.21	0.00e+00	1219.00
IUUC-Mmu-063479	Mus musculus	90.84	0.00e+00	1320.00
IUUC-Mpu-066065	Mustela putorius furo	94.20	0.00e+00	1370.00
IUUC-Mlu-068222	Myotis lucifugus	93.05	0.00e+00	1356.00
IUUC-Nle-069379	Nomascus leucogenys	94.85	0.00e+00	1390.00
IUUC-Opr-070687	Ochotona princeps	73.32	0.00e+00	813.00
IUUC-Oan-073067	Ornithorhynchus anatinus	80.67	0.00e+00	1226.00
IUUC-Ocu-074852	Oryctolagus cuniculus	93.56	0.00e+00	1368.00
IUUC-Oga-089048	Otolemur garnettii	87.50	0.00e+00	1183.00
IUUC-Oar-089339	Ovis aries	99.23	0.00e+00	1476.00
IUUC-Pan-092666	Papio anubis	92.16	0.00e+00	1337.00
IUUC-Psi-093116	Pelodiscus sinensis	75.68	0.00e+00	1162.00
IUUC-Pfo-097394	Poecilia formosa	61.88	0.00e+00	918.00
IUUC-Pab-098567	Pongo abelii	95.10	0.00e+00	1393.00
IUUC-Pca-100997	Procavia capensis	79.64	0.00e+00	1112.00
IUUC-Pva-102500	Pteropus vampyrus	92.40	0.00e+00	1334.00
IUUC-Rno-104974	Rattus norvegicus	91.23	0.00e+00	1297.00
IUUC-Sly-111123	Solanum lycopersicum	35.80	1.00e-09	57.40
IUUC-Stu-112434	Solanum tuberosum	44.23	1.00e-09	57.40
IUUC-Sar-113420	Sorex araneus	87.76	0.00e+00	1275.00
IUUC-Ssc-115679	Sus scrofa	96.68	0.00e+00	1249.00
IUUC-Tgu-117069	Taeniopygia guttata	74.48	0.00e+00	1114.00
IUUC-Tru-118488	Takifugu rubripes	56.34	0.00e+00	813.00
IUUC-Tsy-119243	Tarsius syrichta	85.90	0.00e+00	948.00
IUUC-Tni-120584	Tetraodon nigroviridis	59.82	0.00e+00	905.00
IUUC-Tbe-127994	Tupaia belangeri	78.22	0.00e+00	1125.00
IUUC-Ttr-128839	Tursiops truncatus	95.23	0.00e+00	1377.00
IUUC-Vpa-130144	Vicugna pacos	87.30	0.00e+00	1224.00
IUUC-Xtr-132624	Xenopus tropicalis	70.30	0.00e+00	1071.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence