iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021944

Ensembl Protein ID

ENSCPOP00000006686.2

UniProt Accession

H0VA21; H0VA21_CAVPO

Genbank Protein ID

ENSCPOP00000006686

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02007422

Gene Name

SLX4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000007413.3	ENSCPOT00000007485.2	ENSCPOP00000006686.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/UBZ	6.80e-09	35.8	120	145

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/UBZ

   S: 2    lvCPvCqkm...vdqtdfeeHlDeCl 24
           ++C++Cqk    +++t++e+H+++Cl
   Q: 120  FFCQICQKNlsaMNVTRREQHVNRCL 145
           89***********************8 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

PIPEINASNG DSQSSLSCSM TTAVPSPSKP RTAELVLQRM QQFKRADPER LRHAQDCSLE 60
ATLEENDPQS LQEEMVAGNG NGLGLPATDS DAAVALVLQQ EFGREGTSVQ DENLEEKGLF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAATACCAG AAATTGAACC ACTGGGTATT GAACCCAGTG CCTTCACATT GAGCTATAAT 60
CACCCTTGTG CCCTGCTCAC TGTGTTGTGC AGGCCAAGCT TGAACTTGTG ATCCTCTTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR018574--Structure-sp_endonuc_su_Slx4

PROSITE

PS50097--BTB

Pfam

PF00651--BTB
PF09494--Slx4

SMART

SM00225--BTB

Gene Ontology

GO:0030054--C:cell junction
GO:0005829--C:cytosol
GO:0070522--C:ERCC4-ERCC1 complex
GO:0048476--C:Holliday junction resolvase complex
GO:0000790--C:nuclear chromatin
GO:0000784--C:nuclear chromosome, telomeric region
GO:0005654--C:nucleoplasm
GO:0033557--C:Slx1-Slx4 complex
GO:0048257--F:3'-flap endonuclease activity
GO:0017108--F:5'-flap endonuclease activity
GO:0008821--F:crossover junction endodeoxyribonuclease activity
GO:0008047--F:enzyme activator activity
GO:0010792--P:DNA double-strand break processing involved in repair via single-strand annealing
GO:0006260--P:DNA replication
GO:0000724--P:double-strand break repair via homologous recombination
GO:1904357--P:negative regulation of telomere maintenance via telomere lengthening
GO:0006289--P:nucleotide-excision repair
GO:1904431--P:positive regulation of t-circle formation
GO:0072429--P:response to intra-S DNA damage checkpoint signaling
GO:0090656--P:t-circle formation
GO:0061820--P:telomeric D-loop disassembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001225	Ailuropoda melanoleuca	56.58	0.00e+00	1294.00
IUUC-Apl-003261	Anas platyrhynchos	37.34	0.00e+00	701.00
IUUC-Aca-004455	Anolis carolinensis	59.42	1.00e-18	83.60
IUUC-Acl-008026	Aspergillus clavatus	25.00	2.80e-01	31.20
IUUC-Ame-010993	Astyanax mexicanus	39.29	4.00e-12	64.30
IUUC-Bta-013472	Bos taurus	52.48	0.00e+00	1099.00
IUUC-Cel-018663	Caenorhabditis elegans	36.36	1.30e-02	35.00
IUUC-Cja-019406	Callithrix jacchus	56.61	0.00e+00	1315.00
IUUC-Cfa-020129	Canis familiaris	54.84	0.00e+00	1154.00
IUUC-Csa-023941	Chlorocebus sabaeus	52.12	5.00e-167	581.00
IUUC-Cho-024847	Choloepus hoffmanni	69.08	6.00e-120	426.00
IUUC-Cin-025405	Ciona intestinalis	25.41	1.00e-09	57.40
IUUC-Csv-025916	Ciona savignyi	35.59	3.00e-07	48.50
IUUC-Dre-027764	Danio rerio	35.30	1.00e-71	265.00
IUUC-Dno-030083	Dasypus novemcinctus	51.99	0.00e+00	1104.00
IUUC-Dor-031129	Dipodomys ordii	58.33	0.00e+00	773.00
IUUC-Ete-032536	Echinops telfairi	41.43	5.00e-104	373.00
IUUC-Eca-033407	Equus caballus	58.03	0.00e+00	1200.00
IUUC-Eeu-034473	Erinaceus europaeus	38.23	7.00e-39	156.00
IUUC-Fca-035730	Felis catus	55.99	0.00e+00	1320.00
IUUC-Fal-036850	Ficedula albicollis	45.09	3.00e-134	474.00
IUUC-Gmo-038677	Gadus morhua	41.26	3.00e-31	130.00
IUUC-Gga-041088	Gallus gallus	45.21	3.00e-136	480.00
IUUC-Gac-041824	Gasterosteus aculeatus	39.47	4.00e-25	107.00
IUUC-Ggo-045642	Gorilla gorilla	57.67	0.00e+00	1231.00
IUUC-Hsa-047035	Homo sapiens	58.40	0.00e+00	1354.00
IUUC-Itr-049010	Ictidomys tridecemlineatus	61.26	0.00e+00	1465.00
IUUC-Lch-050364	Latimeria chalumnae	36.98	5.00e-76	280.00
IUUC-Loc-052423	Lepisosteus oculatus	37.93	2.00e-41	165.00
IUUC-Laf-053910	Loxodonta africana	53.58	0.00e+00	1229.00
IUUC-Mcc-055883	Macaca mulatta	58.16	0.00e+00	1392.00
IUUC-Meu-056224	Macropus eugenii	51.10	9.00e-85	308.00
IUUC-Mga-059880	Meleagris gallopavo	45.69	3.00e-139	489.00
IUUC-Mvi-060510	Microbotryum violaceum	34.55	9.00e-03	36.20
IUUC-Mmr-061715	Microcebus murinus	59.74	0.00e+00	1482.00
IUUC-Mdo-062426	Monodelphis domestica	42.51	0.00e+00	891.00
IUUC-Mmu-063947	Mus musculus	58.34	0.00e+00	1426.00
IUUC-Mpu-066184	Mustela putorius furo	64.06	0.00e+00	828.00
IUUC-Mlu-067533	Myotis lucifugus	57.74	0.00e+00	1319.00
IUUC-Nle-069204	Nomascus leucogenys	56.74	0.00e+00	1330.00
IUUC-Opr-070377	Ochotona princeps	63.09	0.00e+00	762.00
IUUC-Ont-072551	Oreochromis niloticus	33.73	4.00e-60	227.00
IUUC-Oan-073350	Ornithorhynchus anatinus	53.47	3.00e-101	362.00
IUUC-Ocu-074915	Oryctolagus cuniculus	50.67	0.00e+00	811.00
IUUC-Ola-087360	Oryzias latipes	46.76	3.00e-34	138.00
IUUC-Oga-089106	Otolemur garnettii	57.16	0.00e+00	1197.00
IUUC-Oar-089289	Ovis aries	51.60	0.00e+00	732.00
IUUC-Ptr-091469	Pan troglodytes	58.30	0.00e+00	1334.00
IUUC-Pan-091841	Papio anubis	56.13	0.00e+00	1092.00
IUUC-Psi-093842	Pelodiscus sinensis	45.61	3.00e-131	463.00
IUUC-Pma-094732	Petromyzon marinus	54.93	3.00e-10	58.20
IUUC-Pfo-097299	Poecilia formosa	37.17	1.00e-32	136.00
IUUC-Pab-098271	Pongo abelii	58.19	0.00e+00	1340.00
IUUC-Pca-100721	Procavia capensis	48.61	0.00e+00	719.00
IUUC-Pva-102276	Pteropus vampyrus	56.88	0.00e+00	1430.00
IUUC-Rno-105619	Rattus norvegicus	56.59	0.00e+00	1366.00
IUUC-Sha-106722	Sarcophilus harrisii	43.85	0.00e+00	698.00
IUUC-Sar-113673	Sorex araneus	57.26	9.00e-60	226.00
IUUC-Ssc-115383	Sus scrofa	62.42	0.00e+00	713.00
IUUC-Tgu-117243	Taeniopygia guttata	49.49	3.00e-94	338.00
IUUC-Tru-118092	Takifugu rubripes	42.86	8.00e-34	137.00
IUUC-Tsy-119362	Tarsius syrichta	50.96	4.00e-140	493.00
IUUC-Tni-120380	Tetraodon nigroviridis	66.67	1.00e-20	92.80
IUUC-Tbe-127404	Tupaia belangeri	43.81	3.00e-170	593.00
IUUC-Ttr-128317	Tursiops truncatus	55.82	0.00e+00	1221.00
IUUC-Uma-129640	Ustilago maydis	32.81	4.00e-04	38.90
IUUC-Xtr-132533	Xenopus tropicalis	40.24	1.00e-98	355.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence