iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036338

Ensembl Protein ID

ENSFCAP00000006777.3

UniProt Accession

M3W7H6; M3W7H6_FELCA

Genbank Protein ID

ENSFCAP00000006777

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02052979

Gene Name

MED16

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000007309.3	ENSFCAT00000007311.3	ENSFCAP00000006777.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.90e-06	27.1	69	101

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           H++ +tcl++  s+ +l+s+  Dg+ik+W++ +
   Q: 69   HSEAITCLEWdqSGSRLLSADADGQIKCWSMAD 101
           99********965599*************9765 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MDLAYVCEWE RWPKSTHCPS VPLACAWSCR NLIAFTTDLR NDDQADLTRM IHILDTEHPW 60
DVHSVNSEHS EAITCLEWDQ SGSRLLSADA DGQIKCWSMA DHLANSWESS VGSLVEGDPI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCAGGAGC TGGTGACTGT CCTCGGGGTG TGACCTGTGG CCTGTGGGCA CAATGGATCT 60
GGCTTACGTC TGCGAGTGGG AGAGATGGCC CAAGAGTACC CACTGTCCGT CGGTGCCTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR021665--Mediator_Med16
IPR011041--Quinoprot_gluc/sorb_DH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF11635--Med16

SMART

SM00320--WD40

Gene Ontology

GO:0016592--C:mediator complex
GO:0016020--C:membrane
GO:0003824--F:catalytic activity
GO:0004872--F:receptor activity
GO:0030375--F:thyroid hormone receptor coactivator activity
GO:0003713--F:transcription coactivator activity
GO:0030521--P:androgen receptor signaling pathway
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006367--P:transcription initiation from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011407	Astyanax mexicanus	73.58	3.00e-177	615.00
IUUC-Bta-012729	Bos taurus	90.29	0.00e+00	795.00
IUUC-Cja-019000	Callithrix jacchus	95.14	7.00e-95	339.00
IUUC-Cfa-020876	Canis familiaris	98.65	0.00e+00	863.00
IUUC-Cpo-021655	Cavia porcellus	94.13	0.00e+00	831.00
IUUC-Dre-027473	Danio rerio	76.51	0.00e+00	714.00
IUUC-Dno-029564	Dasypus novemcinctus	92.78	0.00e+00	820.00
IUUC-Eca-033914	Equus caballus	96.39	0.00e+00	850.00
IUUC-Fal-037249	Ficedula albicollis	87.13	0.00e+00	816.00
IUUC-Gmo-039447	Gadus morhua	72.82	2.00e-168	585.00
IUUC-Gga-041100	Gallus gallus	88.00	0.00e+00	728.00
IUUC-Gac-042603	Gasterosteus aculeatus	72.03	8.00e-160	557.00
IUUC-Ggo-044794	Gorilla gorilla	95.70	0.00e+00	842.00
IUUC-Hsa-045722	Homo sapiens	95.92	0.00e+00	841.00
IUUC-Itr-048948	Ictidomys tridecemlineatus	95.03	0.00e+00	839.00
IUUC-Loc-052871	Lepisosteus oculatus	80.22	0.00e+00	729.00
IUUC-Mcc-055201	Macaca mulatta	95.70	0.00e+00	840.00
IUUC-Mga-059807	Meleagris gallopavo	81.98	0.00e+00	732.00
IUUC-Mmr-060781	Microcebus murinus	95.94	0.00e+00	842.00
IUUC-Mpu-066388	Mustela putorius furo	98.19	0.00e+00	858.00
IUUC-Ont-072316	Oreochromis niloticus	79.01	0.00e+00	699.00
IUUC-Ola-086721	Oryzias latipes	76.13	0.00e+00	659.00
IUUC-Oga-088875	Otolemur garnettii	95.71	0.00e+00	844.00
IUUC-Oar-090444	Ovis aries	93.00	0.00e+00	827.00
IUUC-Ptr-091117	Pan troglodytes	96.10	0.00e+00	827.00
IUUC-Pan-091807	Papio anubis	95.93	0.00e+00	841.00
IUUC-Pfo-097356	Poecilia formosa	78.56	0.00e+00	673.00
IUUC-Pab-097953	Pongo abelii	95.38	0.00e+00	806.00
IUUC-Pca-100896	Procavia capensis	94.58	0.00e+00	829.00
IUUC-Rno-105038	Rattus norvegicus	94.58	0.00e+00	825.00
IUUC-Tgu-116750	Taeniopygia guttata	86.23	0.00e+00	806.00
IUUC-Tru-118405	Takifugu rubripes	77.13	0.00e+00	698.00
IUUC-Tni-120217	Tetraodon nigroviridis	76.68	0.00e+00	697.00
IUUC-Ttr-129222	Tursiops truncatus	94.13	0.00e+00	835.00
IUUC-Xtr-132084	Xenopus tropicalis	81.94	0.00e+00	710.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence