iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073788

UUCD1 version

UUC-OrC-01060

Ensembl Protein ID

ENSOCUP00000026504.1

UniProt Accession

U3KMP5; U3KMP5_RABIT

Protein Name

Uncharacterized protein

Gene Name

USP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000007926.3	ENSOCUT00000007928.2	ENSOCUP00000006850.2
ENSOCUG00000007926.3	ENSOCUT00000033457.1	ENSOCUP00000026504.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.30e-61	207.9	429	784

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l++   +   ++ +++ +++++++s+ +l++e++      k ++              a++p+
   Q: 429  GLINKGNWCYINATLQALVACPPMYHLMKF-LPLYSKA-QRPCTSTPMIDSFVRLMNEFTnmpvppKPRQAlgdkivrdirpgaAFEPT 515
           9***************************99.4444444.35799***************7666654333337777888888888***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsde..........aee 132
            +++ l  +++++s + +q+Da+E+l f+l++l+ee+                    ++ p ++e+ee+ + +++e          +  
   Q: 516  YIYRLLTVIKSSLSeKGRQEDAEEYLGFILNGLHEEMLGlkkllaahgeqlaipngPRSRPGTQEQEEEGEGSEEEweqvgprnktSVT 604
           *9999999999966599********************3355589999999999998555555555555544444444455554333333 PP
   S: 133  kkkkknk......slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkq 215
                 +      ++i+ +F+g+++ +++ ++  ++s + +pf++l+l++++++ +   ++qd+Les +++e+++g    y++k k+++
   Q: 605  ------RqadfvqTPITCIFGGHIR-SVVYQQSSKESATLQPFFTLQLDIQSDKIR---TVQDALESLVARESVQG----YTTKSKQEV 679
           ......1444666***********9.688999999*******************99...****************8....99999**** PP
   S: 216  eaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLiavvvHsG.slssGHYvayvk 300
           e +++++l+klP+vL+lhLkRf ++++++++ k+ k++++p  L++s+ + sp  k+k+   +++Y+L+avv+H+G s+ +GHY+++v 
   Q: 680  EISRRVTLEKLPPVLVLHLKRFVYEKTGGCQ-KLIKNIDYPVDLEISKELLSPGVKNKNfkcHRTYRLFAVVYHHGnSATGGHYTTDVF 767
           ************************9998886.****************999988777777879************************** PP
   S: 301  nekgk.WllfdDskVte 316
           +   + Wl++dD++V+ 
   Q: 768  QIGLNgWLRIDDQSVRI 784
           *87777********976 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MLLMHAVSSS QEHGVQLSVC GWVEGRRDSS RASLLSGHAP GPALPAVLEQ LPPYGGAVLC 60
DGRAAEEPPD GQDYQRIEFG VNEVIEPSAA LPRAPGCGVS STLNPQAPEF ILGCPASSKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCTTTT TTGTTTTTCA GTATATTTTT GGAGACTTTA GTCCTGATGA ATTCAATCAG 60
TTCTTTGTGA CTCCTCGCTC TTCCGTTGAG GTAAGATAAA GCTGTTGCAG TGAGTGAAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	30.48	8.00e-38	152.00
IUUC-Aml-001584	Ailuropoda melanoleuca	79.97	0.00e+00	1101.00
IUUC-Atr-002927	Amborella trichopoda	35.16	4.00e-52	199.00
IUUC-Apl-003988	Anas platyrhynchos	73.59	0.00e+00	1005.00
IUUC-Aca-004461	Anolis carolinensis	89.61	4.00e-147	513.00
IUUC-Aly-006038	Arabidopsis lyrata	34.15	6.00e-47	181.00
IUUC-Ath-007328	Arabidopsis thaliana	34.15	7.00e-47	181.00
IUUC-Ago-007717	Ashbya gossypii	27.46	4.00e-32	133.00
IUUC-Acl-008188	Aspergillus clavatus	35.91	6.00e-58	219.00
IUUC-Afl-008456	Aspergillus flavus	38.65	4.00e-44	171.00
IUUC-Afu-009067	Aspergillus fumigatus	35.73	3.00e-60	226.00
IUUC-Ani-009483	Aspergillus nidulans	32.02	7.00e-58	218.00
IUUC-Ang-009639	Aspergillus niger	37.03	6.00e-57	215.00
IUUC-Aor-010040	Aspergillus oryzae	34.41	5.00e-56	213.00
IUUC-Ate-010310	Aspergillus terreus	35.27	1.00e-58	221.00
IUUC-Ame-011012	Astyanax mexicanus	70.73	1.00e-158	553.00
IUUC-Bgr-012311	Blumeria graminis	34.59	1.00e-39	158.00
IUUC-Bta-013299	Bos taurus	78.92	0.00e+00	1062.00
IUUC-Bci-013783	Botrytis cinerea	37.33	2.00e-54	207.00
IUUC-Bdi-015039	Brachypodium distachyon	31.58	5.00e-43	169.00
IUUC-Bol-015806	Brassica oleracea	35.68	8.00e-54	204.00
IUUC-Bra-017076	Brassica rapa	35.95	5.00e-54	205.00
IUUC-Cja-018715	Callithrix jacchus	80.03	0.00e+00	1127.00
IUUC-Cfa-020194	Canis familiaris	80.38	0.00e+00	1119.00
IUUC-Cpo-022272	Cavia porcellus	70.68	0.00e+00	909.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	33.71	1.00e-30	127.00
IUUC-Csa-023310	Chlorocebus sabaeus	80.16	0.00e+00	1130.00
IUUC-Cho-024966	Choloepus hoffmanni	75.14	0.00e+00	763.00
IUUC-Cin-025616	Ciona intestinalis	47.09	4.00e-92	332.00
IUUC-Csv-026043	Ciona savignyi	44.84	1.00e-86	313.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	35.14	8.00e-45	175.00
IUUC-Cne-026962	Cryptococcus neoformans	34.65	1.00e-49	192.00
IUUC-Cme-027113	Cyanidioschyzon merolae	30.92	2.00e-32	133.00
IUUC-Dno-029489	Dasypus novemcinctus	79.60	0.00e+00	1151.00
IUUC-Dor-031068	Dipodomys ordii	69.38	7.00e-128	451.00
IUUC-Dse-031553	Dothistroma septosporum	38.17	2.00e-53	204.00
IUUC-Dme-031759	Drosophila melanogaster	41.07	7.00e-73	269.00
IUUC-Ete-032549	Echinops telfairi	73.24	0.00e+00	818.00
IUUC-Eca-033380	Equus caballus	79.57	0.00e+00	1122.00
IUUC-Eeu-034818	Erinaceus europaeus	76.49	0.00e+00	1077.00
IUUC-Fca-035535	Felis catus	78.13	0.00e+00	1014.00
IUUC-Fal-036627	Ficedula albicollis	72.18	0.00e+00	977.00
IUUC-Fox-037904	Fusarium oxysporum	37.05	7.00e-51	195.00
IUUC-Fso-038170	Fusarium solani	33.72	3.00e-49	190.00
IUUC-Gmo-039499	Gadus morhua	67.12	3.00e-176	612.00
IUUC-Ggr-040042	Gaeumannomyces graminis	35.73	1.00e-58	221.00
IUUC-Gga-040571	Gallus gallus	73.69	0.00e+00	1003.00
IUUC-Gac-041345	Gasterosteus aculeatus	73.74	4.00e-178	618.00
IUUC-Gma-044407	Glycine max	35.71	3.00e-52	199.00
IUUC-Ggo-044652	Gorilla gorilla	80.78	0.00e+00	1149.00
IUUC-Hsa-045864	Homo sapiens	81.05	0.00e+00	1155.00
IUUC-Hvu-047071	Hordeum vulgare	33.42	3.00e-46	179.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	85.51	0.00e+00	915.00
IUUC-Kpa-049132	Komagataella pastoris	31.12	8.00e-42	164.00
IUUC-Lch-050040	Latimeria chalumnae	68.45	0.00e+00	870.00
IUUC-Loc-052449	Lepisosteus oculatus	71.40	0.00e+00	655.00
IUUC-Lma-053248	Leptosphaeria maculans	36.22	6.00e-55	209.00
IUUC-Laf-054121	Loxodonta africana	79.57	0.00e+00	1127.00
IUUC-Mcc-055514	Macaca mulatta	80.56	0.00e+00	1137.00
IUUC-Meu-056873	Macropus eugenii	66.14	0.00e+00	749.00
IUUC-Mor-057243	Magnaporthe oryzae	34.82	1.00e-55	211.00
IUUC-Mpo-057439	Magnaporthe poae	35.73	2.00e-58	220.00
IUUC-Mtr-058457	Medicago truncatula	34.62	3.00e-49	189.00
IUUC-Mla-058929	Melampsora laricipopulina	30.89	1.00e-50	194.00
IUUC-Mga-060157	Meleagris gallopavo	71.88	0.00e+00	997.00
IUUC-Mvi-060442	Microbotryum violaceum	35.32	4.00e-55	210.00
IUUC-Mmr-061062	Microcebus murinus	80.43	0.00e+00	1152.00
IUUC-Mdo-062798	Monodelphis domestica	74.53	0.00e+00	1045.00
IUUC-Mmu-064050	Mus musculus	74.46	0.00e+00	1050.00
IUUC-Mac-065202	Musa acuminata	34.69	1.00e-45	176.00
IUUC-Mpu-066554	Mustela putorius furo	79.52	0.00e+00	1086.00
IUUC-Mlu-068003	Myotis lucifugus	78.36	0.00e+00	1082.00
IUUC-Nfi-068612	Neosartorya fischeri	36.14	6.00e-59	222.00
IUUC-Ncr-068878	Neurospora crassa	35.31	1.00e-48	188.00
IUUC-Nle-069661	Nomascus leucogenys	80.83	0.00e+00	1139.00
IUUC-Opr-070944	Ochotona princeps	83.74	7.00e-174	603.00
IUUC-Ont-071266	Oreochromis niloticus	54.86	0.00e+00	709.00
IUUC-Oan-073442	Ornithorhynchus anatinus	74.86	0.00e+00	1016.00
IUUC-Oba-075085	Oryza barthii	34.13	3.00e-31	128.00
IUUC-Obr-076663	Oryza brachyantha	33.06	2.00e-39	157.00
IUUC-Ogl-076937	Oryza glaberrima	30.47	6.00e-43	168.00
IUUC-Ogu-078909	Oryza glumaepatula	30.65	5.00e-41	162.00
IUUC-Oin-079617	Oryza indica	31.33	2.00e-44	174.00
IUUC-Olo-081043	Oryza longistaminata	25.83	3.00e-20	93.20
IUUC-Oni-082914	Oryza nivara	30.65	4.00e-41	162.00
IUUC-Oru-084878	Oryza rufipogon	30.65	4.00e-41	162.00
IUUC-Osa-085822	Oryza sativa	31.33	7.00e-45	174.00
IUUC-Ola-086931	Oryzias latipes	54.68	0.00e+00	686.00
IUUC-Oga-088443	Otolemur garnettii	80.51	0.00e+00	1154.00
IUUC-Oar-089325	Ovis aries	76.73	0.00e+00	993.00
IUUC-Ptr-091584	Pan troglodytes	77.82	0.00e+00	1068.00
IUUC-Pan-092551	Papio anubis	78.42	0.00e+00	1099.00
IUUC-Psi-093366	Pelodiscus sinensis	69.64	0.00e+00	656.00
IUUC-Pno-095136	Phaeosphaeria nodorum	34.33	8.00e-49	188.00
IUUC-Ppa-095574	Physcomitrella patens	35.42	1.00e-52	201.00
IUUC-Pfo-097462	Poecilia formosa	76.82	0.00e+00	645.00
IUUC-Pab-098547	Pongo abelii	80.78	0.00e+00	1135.00
IUUC-Pop-099529	Populus trichocarpa	37.36	2.00e-54	206.00
IUUC-Pca-101066	Procavia capensis	72.02	0.00e+00	958.00
IUUC-Ppe-102110	Prunus persica	37.33	2.00e-53	203.00
IUUC-Pva-103015	Pteropus vampyrus	73.73	0.00e+00	1018.00
IUUC-Ptt-103998	Puccinia triticina	31.76	2.00e-49	190.00
IUUC-Pte-104417	Pyrenophora teres	33.94	2.00e-51	197.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	34.88	6.00e-52	199.00
IUUC-Rno-105533	Rattus norvegicus	75.44	0.00e+00	1061.00
IUUC-Sce-106160	Saccharomyces cerevisiae	27.27	1.00e-30	128.00
IUUC-Sha-106590	Sarcophilus harrisii	74.80	0.00e+00	1046.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	36.74	2.00e-51	196.00
IUUC-Spo-108353	Schizosaccharomyces pombe	37.70	6.00e-59	221.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	37.03	2.00e-53	204.00
IUUC-Smo-108842	Selaginella moellendorffii	36.22	2.00e-30	125.00
IUUC-Sit-110781	Setaria italica	31.33	8.00e-48	185.00
IUUC-Sly-111797	Solanum lycopersicum	35.62	1.00e-52	201.00
IUUC-Stu-112188	Solanum tuberosum	36.41	8.00e-53	201.00
IUUC-Sbi-114862	Sorghum bicolor	32.04	2.00e-40	160.00
IUUC-Sre-115162	Sporisorium reilianum	46.24	3.00e-42	166.00
IUUC-Ssc-115505	Sus scrofa	90.81	7.00e-143	499.00
IUUC-Tgu-116535	Taeniopygia guttata	71.77	0.00e+00	980.00
IUUC-Tru-117542	Takifugu rubripes	75.63	0.00e+00	647.00
IUUC-Tni-120200	Tetraodon nigroviridis	54.86	0.00e+00	699.00
IUUC-Tca-121548	Theobroma cacao	35.03	9.00e-41	161.00
IUUC-Tre-122124	Trichoderma reesei	34.53	3.00e-56	213.00
IUUC-Tvi-122457	Trichoderma virens	34.59	3.00e-50	193.00
IUUC-Tae-125646	Triticum aestivum	33.88	4.00e-48	186.00
IUUC-Tme-127180	Tuber melanosporum	41.05	7.00e-68	251.00
IUUC-Tbe-127530	Tupaia belangeri	70.17	0.00e+00	892.00
IUUC-Ttr-128549	Tursiops truncatus	70.72	0.00e+00	963.00
IUUC-Uma-129381	Ustilago maydis	45.16	5.00e-42	166.00
IUUC-Vda-129889	Verticillium dahliae	32.79	2.00e-50	194.00
IUUC-Vpa-130100	Vicugna pacos	73.90	0.00e+00	998.00
IUUC-Vvi-131366	Vitis vinifera	36.12	1.00e-56	213.00
IUUC-Xtr-132048	Xenopus tropicalis	74.12	0.00e+00	791.00
IUUC-Xma-133593	Xiphophorus maculatus	76.14	0.00e+00	648.00
IUUC-Yli-134338	Yarrowia lipolytica	30.31	1.00e-27	118.00
IUUC-Zma-135255	Zea mays	31.01	2.00e-48	188.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence