iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033344

UUCD1 version

UUC-EqC-00345

Ensembl Protein ID

ENSECAP00000020398.1

UniProt Accession

F6VSB5; F6VSB5_HORSE

Protein Name

Uncharacterized protein

Gene Name

WDR59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000022834.1	ENSECAT00000024547.1	ENSECAP00000020398.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.20e-20	70.3	190	224

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd..tllvsGsdDgtikvWDlrtg 33
           H +++++l++ +d  ++l+++s D+++k WD+r+ 
   Q: 190  HLSKIHGLDWhPDseHILATSSQDNSVKFWDYRQP 224
           99*********6665778*************9876 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAARWSSENV VVEFRDSQAT AMSVDCLGQH AVLSGRRFLY IVNLDAPFEG HRKISRQSKW 60
DIGAVQWNPH DSFAHYFAAS SNQRIDLYKW KDGSGEVGTT LQGHTRVISD LDWAVFEPDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTGGGTGTC GGGGGTGGGA AGGTGCCGTC TTAGGGCCCG GGCGGCGGGG CGCGGCAGAT 60
GGCAGCGCGA TGGAGCAGCG AGAACGTGGT AGTGGAGTTC CGCGACTCCC AGGTGAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50908--RWD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00591--RWD
SM00320--WD40

Gene Ontology

GO:0061700--C:GATOR2 complex
GO:0034198--P:cellular response to amino acid starvation
GO:0032008--P:positive regulation of TOR signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002149	Ailuropoda melanoleuca	97.64	0.00e+00	1934.00
IUUC-Apl-004021	Anas platyrhynchos	89.47	0.00e+00	1705.00
IUUC-Aca-004977	Anolis carolinensis	85.01	0.00e+00	1715.00
IUUC-Ago-007961	Ashbya gossypii	29.48	2.00e-57	218.00
IUUC-Acl-008161	Aspergillus clavatus	29.21	9.00e-56	212.00
IUUC-Afl-008686	Aspergillus flavus	28.07	7.00e-58	219.00
IUUC-Afu-008932	Aspergillus fumigatus	34.57	4.00e-52	200.00
IUUC-Ani-009493	Aspergillus nidulans	34.35	4.00e-54	207.00
IUUC-Ang-009876	Aspergillus niger	28.71	7.00e-58	219.00
IUUC-Aor-009926	Aspergillus oryzae	28.07	7.00e-58	219.00
IUUC-Ate-010274	Aspergillus terreus	27.55	2.00e-55	211.00
IUUC-Ame-011297	Astyanax mexicanus	70.53	0.00e+00	1413.00
IUUC-Bgr-012173	Blumeria graminis	31.48	3.00e-44	174.00
IUUC-Bta-013261	Bos taurus	97.95	0.00e+00	1945.00
IUUC-Bci-013971	Botrytis cinerea	32.84	1.00e-46	182.00
IUUC-Cja-019167	Callithrix jacchus	96.51	0.00e+00	1919.00
IUUC-Cfa-020287	Canis familiaris	97.02	0.00e+00	1920.00
IUUC-Cpo-022510	Cavia porcellus	94.28	0.00e+00	1820.00
IUUC-Csa-023474	Chlorocebus sabaeus	96.07	0.00e+00	1949.00
IUUC-Cho-024634	Choloepus hoffmanni	93.14	0.00e+00	788.00
IUUC-Cin-025642	Ciona intestinalis	33.17	2.00e-134	473.00
IUUC-Csv-025848	Ciona savignyi	45.15	4.00e-55	207.00
IUUC-Cgl-026531	Colletotrichum gloeosporioides	32.80	1.00e-44	175.00
IUUC-Cne-027088	Cryptococcus neoformans	31.80	1.00e-43	172.00
IUUC-Dre-028753	Danio rerio	71.81	0.00e+00	1400.00
IUUC-Dno-029733	Dasypus novemcinctus	95.58	0.00e+00	1888.00
IUUC-Dor-030781	Dipodomys ordii	97.65	0.00e+00	988.00
IUUC-Dme-031803	Drosophila melanogaster	34.21	3.00e-148	519.00
IUUC-Ete-032622	Echinops telfairi	87.89	0.00e+00	1706.00
IUUC-Eeu-034523	Erinaceus europaeus	87.24	0.00e+00	1662.00
IUUC-Fca-035650	Felis catus	98.05	0.00e+00	1944.00
IUUC-Fal-037404	Ficedula albicollis	89.24	0.00e+00	1740.00
IUUC-Fox-037955	Fusarium oxysporum	31.66	4.00e-43	170.00
IUUC-Fso-038289	Fusarium solani	33.23	6.00e-47	183.00
IUUC-Gmo-038547	Gadus morhua	67.77	0.00e+00	1389.00
IUUC-Ggr-039858	Gaeumannomyces graminis	36.46	4.00e-43	171.00
IUUC-Gga-041030	Gallus gallus	89.22	0.00e+00	1749.00
IUUC-Gac-042581	Gasterosteus aculeatus	71.43	0.00e+00	1440.00
IUUC-Ggo-044641	Gorilla gorilla	97.64	0.00e+00	1943.00
IUUC-Hsa-046134	Homo sapiens	97.84	0.00e+00	1943.00
IUUC-Itr-048551	Ictidomys tridecemlineatus	96.75	0.00e+00	753.00
IUUC-Kpa-049091	Komagataella pastoris	32.63	9.00e-46	179.00
IUUC-Lch-050288	Latimeria chalumnae	75.15	0.00e+00	1473.00
IUUC-Loc-052802	Lepisosteus oculatus	74.02	0.00e+00	1495.00
IUUC-Lma-053296	Leptosphaeria maculans	32.70	1.00e-48	189.00
IUUC-Laf-053997	Loxodonta africana	95.97	0.00e+00	1959.00
IUUC-Mcc-055855	Macaca mulatta	97.95	0.00e+00	1931.00
IUUC-Meu-056898	Macropus eugenii	95.96	0.00e+00	739.00
IUUC-Mor-056913	Magnaporthe oryzae	34.98	1.00e-42	169.00
IUUC-Mpo-057612	Magnaporthe poae	36.46	1.00e-43	172.00
IUUC-Mla-059097	Melampsora laricipopulina	31.90	4.00e-47	183.00
IUUC-Mga-059218	Meleagris gallopavo	89.24	0.00e+00	1716.00
IUUC-Mvi-060251	Microbotryum violaceum	31.29	1.00e-46	182.00
IUUC-Mmr-061093	Microcebus murinus	94.25	0.00e+00	1856.00
IUUC-Mdo-062757	Monodelphis domestica	93.29	0.00e+00	1830.00
IUUC-Mmu-063839	Mus musculus	94.36	0.00e+00	1927.00
IUUC-Mpu-065977	Mustela putorius furo	97.64	0.00e+00	1933.00
IUUC-Mlu-067460	Myotis lucifugus	95.88	0.00e+00	1927.00
IUUC-Nfi-068250	Neosartorya fischeri	34.57	3.00e-52	201.00
IUUC-Ncr-068710	Neurospora crassa	32.45	2.00e-45	178.00
IUUC-Nle-070011	Nomascus leucogenys	97.74	0.00e+00	1938.00
IUUC-Opr-070731	Ochotona princeps	90.55	0.00e+00	1759.00
IUUC-Ont-072165	Oreochromis niloticus	70.74	0.00e+00	1429.00
IUUC-Oan-072887	Ornithorhynchus anatinus	91.78	0.00e+00	1855.00
IUUC-Ocu-073926	Oryctolagus cuniculus	95.20	0.00e+00	1766.00
IUUC-Ola-087111	Oryzias latipes	67.37	0.00e+00	1357.00
IUUC-Oga-088850	Otolemur garnettii	97.64	0.00e+00	1932.00
IUUC-Oar-090291	Ovis aries	97.74	0.00e+00	1940.00
IUUC-Ptr-091044	Pan troglodytes	97.54	0.00e+00	1932.00
IUUC-Pan-092374	Papio anubis	95.87	0.00e+00	1945.00
IUUC-Psi-093170	Pelodiscus sinensis	55.60	0.00e+00	967.00
IUUC-Pma-094544	Petromyzon marinus	65.85	7.00e-171	593.00
IUUC-Pno-095068	Phaeosphaeria nodorum	30.56	1.00e-44	175.00
IUUC-Pfo-096480	Poecilia formosa	68.21	0.00e+00	1335.00
IUUC-Pab-098134	Pongo abelii	96.39	0.00e+00	1895.00
IUUC-Pca-100763	Procavia capensis	75.87	0.00e+00	1004.00
IUUC-Pva-102544	Pteropus vampyrus	96.61	0.00e+00	1926.00
IUUC-Pgr-103257	Puccinia graminis	32.33	5.00e-50	193.00
IUUC-Ptt-103942	Puccinia triticina	31.55	1.00e-45	178.00
IUUC-Pte-104065	Pyrenophora teres	32.20	4.00e-46	181.00
IUUC-Rno-105468	Rattus norvegicus	92.38	0.00e+00	1751.00
IUUC-Sce-106356	Saccharomyces cerevisiae	28.71	8.00e-59	222.00
IUUC-Sha-106662	Sarcophilus harrisii	95.10	0.00e+00	1850.00
IUUC-Sja-107973	Schizosaccharomyces japonicus	28.12	1.00e-72	268.00
IUUC-Spo-108265	Schizosaccharomyces pombe	33.44	3.00e-49	191.00
IUUC-Ssl-108662	Sclerotinia sclerotiorum	33.43	8.00e-46	179.00
IUUC-Sar-113525	Sorex araneus	93.89	0.00e+00	1084.00
IUUC-Sre-115163	Sporisorium reilianum	37.05	2.00e-40	161.00
IUUC-Ssc-115381	Sus scrofa	96.87	0.00e+00	1054.00
IUUC-Tgu-116525	Taeniopygia guttata	85.85	0.00e+00	1676.00
IUUC-Tru-118432	Takifugu rubripes	69.54	0.00e+00	1420.00
IUUC-Tsy-119306	Tarsius syrichta	80.15	0.00e+00	1243.00
IUUC-Tni-120757	Tetraodon nigroviridis	69.17	0.00e+00	1383.00
IUUC-Tre-122187	Trichoderma reesei	35.03	5.00e-48	187.00
IUUC-Tvi-122367	Trichoderma virens	35.35	1.00e-47	185.00
IUUC-Tme-126986	Tuber melanosporum	25.62	7.00e-65	242.00
IUUC-Tbe-127800	Tupaia belangeri	82.06	0.00e+00	1375.00
IUUC-Ttr-129154	Tursiops truncatus	89.23	0.00e+00	1713.00
IUUC-Uma-129366	Ustilago maydis	35.97	1.00e-39	159.00
IUUC-Vda-129827	Verticillium dahliae	33.86	1.00e-47	185.00
IUUC-Vpa-130493	Vicugna pacos	98.12	0.00e+00	1897.00
IUUC-Xtr-131941	Xenopus tropicalis	81.54	0.00e+00	1600.00
IUUC-Xma-133903	Xiphophorus maculatus	69.51	0.00e+00	1406.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence