iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Acl-008333

Ensembl Protein ID

CADACLAP00008027

UniProt Accession

A1CTV1; A1CTV1_ASPCL

Genbank Protein ID

EAW06738.1

Protein Name

NEDD8-activating enzyme E1 regulatory subunit

Genbank Nucleotide ID

DS027060

Gene Name

ACLA_084330

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADACLAG00008218	CADACLAT00008218	CADACLAP00008027

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	1.30e-59	201.4	19	547

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagg............lGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaeal 81
           YDRQ+rlw + +q++l++++vll++ +g            +G+E lKnLvl G+g +t+vD + v++ +l+ +F++++e+ gk +Ae +++ l
   Q: 19   YDRQLRLWAASGQQALEESRVLLINSDGpwgnqstgasgvVGVEALKNLVLPGIGGFTIVDPAVVTKPDLGVNFFLEEESLGKFRAEETCRLL 111
           ************************97665555555556669**************************************************** PP
   S: 82   kelnpdvnveaheesiteleeeiv.FfkkfdvVvla.ldnrearrkvnrlclnarvpliesgtlGllGqvrviik.gltecyscsd....dpp 167
           +elnpdv++++ ++ i e  ++++ F++++++V+++  ++r++  +v +   ++++p + + + G+++  +  ++ ++++ + ++d    +++
   Q: 112  RELNPDVEGSFRSKTIAEVLQQEPdFLTQHKLVLVTgPMKRSSLETVCKTAKALNIPVLYTHSVGFYSVFSLQLPaEFPIVETHPDpestQDL 204
           **********************99*********876267888888888888888****************999994577777777799999** PP
   S: 168  qktiPfctlket..........pnaaehtiewavlfnklleeeageeevlekldseekeegkdkvkselks....edeenfeeaieiavkafa 246
           ++ +P+++l+            +  ++ +++++ l+ ++le+++ +++++++++++ek+e++++v++++++      een++ea+++++k+++
   Q: 205  RLLNPWPELAAAagsignlesmEDHQHGHVPYVLLLLHYLEKWKRAHDGNAPSNYKEKSEFRELVRASARTntpeGGEENYDEAVAAVLKSLN 297
           **********996666666555559**********************************************44444578************** PP
   S: 247  kttins.ikqllksfecdivtkskspfwv................................................................ 274
           +++  + i+++++s +c+++++++++fwv                                                                
   Q: 298  PFSLRGpIREIFESGQCKNLQQDSADFWViasavhefyqthqvlplpgslpdmkaqsadyvslqniykskarqdveeviatvrrleaqlgprl 390
           ********************************************************************************************* PP
   S: 275  .........sfcsnaealq...........vpekvekdeevvkasap.......lylllralerfekkkgrkpgelsfekddds...avdlvt 337
                     fc+na+ ++           + ++ +  +  +++s++        ++l r++ + ++ +     e s++ d      + +++ 
   Q: 391  aaipekeieIFCKNAAHIKvihgrdiphveEAHTLKTITNSLSSSESlipifiaCQVLDRVVTQIQEGNVA---ETSLDADILWdtqIHQVIG 480
           *******************7777776665544666666666666666999444444444455555554444...4555555433225777777 PP
   S: 338  aaanlraeslgiep.kldddlikeiagniipaiattnavvgGlaaqEviKvvsgkfeplknfflfda 403
           ++++      g  + +   ++++e+ +++ ++++ ++a  gGl+aqE++Kv++ +++pl+n+ +fd+
   Q: 481  DLSSNNPGAVGEGArERILEATQELRRTEGGELHNISALTGGLVAQEALKVMTRQYVPLDNTCIFDG 547
           777655555555554455567899*****************************************97 PP

Organism

Aspergillus clavatus

Functional Description
(View)

Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.

Protein Sequence
(Fasta)

MTDAFPSALV GPSSKERKYD RQLRLWAASG QQALEESRVL LINSDGPWGN QSTGASGVVG 60
VEALKNLVLP GIGGFTIVDP AVVTKPDLGV NFFLEEESLG KFRAEETCRL LRELNPDVEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTGATG CTTTCCCCAG TGCCCTGGTA GGGCCATCCT CCAAAGAAAG AAAGTATGAT 60
CGCCAGCTGC GCTTGTGGGC GGCTAGCGGA CAGCAAGCTC TGGAAGAGTC CCGGGTCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR030667--APP-BP1
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF00899--ThiF

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

KEGG

act:ACLA_084330

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000764	Aegilops tauschii	33.33	4.00e-76	276.00
IUUC-Aml-002333	Ailuropoda melanoleuca	34.41	8.00e-87	312.00
IUUC-Atr-002644	Amborella trichopoda	31.68	2.00e-66	244.00
IUUC-Apl-003446	Anas platyrhynchos	33.21	2.00e-76	278.00
IUUC-Aca-004450	Anolis carolinensis	32.86	1.00e-82	298.00
IUUC-Aly-006187	Arabidopsis lyrata	33.94	1.00e-77	281.00
IUUC-Ath-007600	Arabidopsis thaliana	34.06	2.00e-77	281.00
IUUC-Ago-007900	Ashbya gossypii	26.74	5.00e-35	140.00
IUUC-Afl-008529	Aspergillus flavus	76.88	0.00e+00	857.00
IUUC-Afu-009071	Aspergillus fumigatus	83.69	0.00e+00	947.00
IUUC-Ani-009443	Aspergillus nidulans	72.76	0.00e+00	788.00
IUUC-Ang-009669	Aspergillus niger	75.31	0.00e+00	873.00
IUUC-Aor-009914	Aspergillus oryzae	75.84	0.00e+00	845.00
IUUC-Ate-010450	Aspergillus terreus	75.09	0.00e+00	851.00
IUUC-Ame-011183	Astyanax mexicanus	34.30	3.00e-89	320.00
IUUC-Bgr-012111	Blumeria graminis	44.60	1.00e-121	428.00
IUUC-Bta-012583	Bos taurus	34.53	6.00e-88	316.00
IUUC-Bci-013892	Botrytis cinerea	47.39	4.00e-137	479.00
IUUC-Bdi-014592	Brachypodium distachyon	33.64	1.00e-74	272.00
IUUC-Bol-016401	Brassica oleracea	32.60	1.00e-77	282.00
IUUC-Bra-017506	Brassica rapa	32.60	1.00e-74	271.00
IUUC-Cel-018456	Caenorhabditis elegans	30.42	3.00e-57	214.00
IUUC-Cja-020007	Callithrix jacchus	33.99	8.00e-86	309.00
IUUC-Cfa-020324	Canis familiaris	34.17	1.00e-87	315.00
IUUC-Cpo-022248	Cavia porcellus	31.75	4.00e-46	177.00
IUUC-Csa-023149	Chlorocebus sabaeus	31.23	5.00e-64	236.00
IUUC-Cho-024537	Choloepus hoffmanni	28.30	1.00e-49	189.00
IUUC-Cin-025763	Ciona intestinalis	35.45	4.00e-85	306.00
IUUC-Csv-026113	Ciona savignyi	34.35	3.00e-86	310.00
IUUC-Cgl-026428	Colletotrichum gloeosporioides	42.22	4.00e-119	419.00
IUUC-Cne-026884	Cryptococcus neoformans	28.67	3.00e-61	227.00
IUUC-Cme-027210	Cyanidioschyzon merolae	27.35	8.00e-14	70.10
IUUC-Dre-028140	Danio rerio	34.65	4.00e-87	313.00
IUUC-Dno-030033	Dasypus novemcinctus	35.90	5.00e-78	283.00
IUUC-Dor-030513	Dipodomys ordii	50.43	9.00e-24	102.00
IUUC-Dse-031536	Dothistroma septosporum	45.36	4.00e-136	476.00
IUUC-Dme-031683	Drosophila melanogaster	33.16	3.00e-77	280.00
IUUC-Ete-032420	Echinops telfairi	30.50	2.00e-67	248.00
IUUC-Eca-033992	Equus caballus	31.52	6.00e-62	229.00
IUUC-Eeu-034713	Erinaceus europaeus	52.78	1.00e-25	109.00
IUUC-Fca-036548	Felis catus	34.17	6.00e-87	313.00
IUUC-Fal-037600	Ficedula albicollis	32.66	7.00e-76	276.00
IUUC-Fox-038037	Fusarium oxysporum	44.54	1.00e-130	458.00
IUUC-Fso-038387	Fusarium solani	44.09	2.00e-131	460.00
IUUC-Gmo-038562	Gadus morhua	33.93	8.00e-88	315.00
IUUC-Ggr-040005	Gaeumannomyces graminis	45.33	4.00e-136	476.00
IUUC-Gga-041129	Gallus gallus	34.65	2.00e-82	297.00
IUUC-Gac-042558	Gasterosteus aculeatus	33.10	3.00e-83	300.00
IUUC-Gma-043610	Glycine max	33.64	3.00e-73	267.00
IUUC-Ggo-045611	Gorilla gorilla	34.86	6.00e-87	313.00
IUUC-Hsa-046563	Homo sapiens	34.87	2.00e-88	318.00
IUUC-Hvu-047790	Hordeum vulgare	30.73	3.00e-45	174.00
IUUC-Itr-048066	Ictidomys tridecemlineatus	34.70	4.00e-87	313.00
IUUC-Kpa-049309	Komagataella pastoris	31.68	2.00e-71	261.00
IUUC-Lch-050038	Latimeria chalumnae	34.57	1.00e-81	295.00
IUUC-Lpe-051535	Leersia perrieri	30.29	5.00e-56	210.00
IUUC-Loc-051917	Lepisosteus oculatus	31.90	2.00e-75	275.00
IUUC-Lma-053112	Leptosphaeria maculans	50.00	2.00e-158	550.00
IUUC-Laf-053690	Loxodonta africana	34.35	4.00e-88	317.00
IUUC-Mcc-055117	Macaca mulatta	33.57	1.00e-82	298.00
IUUC-Meu-056761	Macropus eugenii	27.74	3.00e-56	211.00
IUUC-Mor-057230	Magnaporthe oryzae	44.97	6.00e-135	472.00
IUUC-Mpo-057514	Magnaporthe poae	46.42	2.00e-127	447.00
IUUC-Mtr-058551	Medicago truncatula	32.69	8.00e-67	246.00
IUUC-Mla-059183	Melampsora laricipopulina	32.86	5.00e-82	296.00
IUUC-Mga-060144	Meleagris gallopavo	33.63	3.00e-78	284.00
IUUC-Mvi-060221	Microbotryum violaceum	36.67	6.00e-67	246.00
IUUC-Mmr-061325	Microcebus murinus	34.16	2.00e-83	301.00
IUUC-Mdo-062532	Monodelphis domestica	35.00	6.00e-88	316.00
IUUC-Mmu-063956	Mus musculus	34.53	5.00e-88	316.00
IUUC-Mac-064521	Musa acuminata	32.74	2.00e-74	271.00
IUUC-Mpu-066716	Mustela putorius furo	34.10	1.00e-77	281.00
IUUC-Mlu-067459	Myotis lucifugus	34.47	7.00e-89	319.00
IUUC-Nfi-068245	Neosartorya fischeri	83.33	0.00e+00	945.00
IUUC-Ncr-068910	Neurospora crassa	46.27	2.00e-142	497.00
IUUC-Nle-070034	Nomascus leucogenys	32.78	3.00e-78	284.00
IUUC-Opr-070552	Ochotona princeps	33.55	3.00e-65	241.00
IUUC-Ont-071426	Oreochromis niloticus	35.50	1.00e-91	328.00
IUUC-Oan-073389	Ornithorhynchus anatinus	31.30	2.00e-56	211.00
IUUC-Ocu-074911	Oryctolagus cuniculus	34.17	8.00e-87	312.00
IUUC-Oba-075437	Oryza barthii	32.24	8.00e-64	236.00
IUUC-Obr-076684	Oryza brachyantha	31.33	9.00e-58	216.00
IUUC-Ogl-077170	Oryza glaberrima	32.24	8.00e-64	236.00
IUUC-Ogu-078844	Oryza glumaepatula	31.80	4.00e-57	213.00
IUUC-Oin-079105	Oryza indica	32.24	5.00e-64	236.00
IUUC-Olo-080943	Oryza longistaminata	30.65	5.00e-51	193.00
IUUC-Oni-082891	Oryza nivara	31.15	4.00e-58	217.00
IUUC-Opu-083457	Oryza punctata	32.24	5.00e-63	233.00
IUUC-Oru-084960	Oryza rufipogon	30.65	4.00e-51	193.00
IUUC-Osa-085358	Oryza sativa	32.24	1.00e-63	235.00
IUUC-Ola-086420	Oryzias latipes	31.40	8.00e-52	195.00
IUUC-Olu-087625	Ostreococcus lucimarinus	24.22	4.00e-37	147.00
IUUC-Oga-088810	Otolemur garnettii	34.53	9.00e-89	318.00
IUUC-Oar-089196	Ovis aries	34.16	1.00e-85	308.00
IUUC-Ptr-090617	Pan troglodytes	34.69	2.00e-87	314.00
IUUC-Pan-092761	Papio anubis	34.70	4.00e-88	317.00
IUUC-Psi-093191	Pelodiscus sinensis	33.33	3.00e-80	290.00
IUUC-Pma-094380	Petromyzon marinus	37.72	5.00e-79	286.00
IUUC-Pno-095084	Phaeosphaeria nodorum	46.99	2.00e-135	475.00
IUUC-Ppa-095875	Physcomitrella patens	31.27	2.00e-68	251.00
IUUC-Pfo-096467	Poecilia formosa	35.47	2.00e-90	324.00
IUUC-Pab-098255	Pongo abelii	36.12	2.00e-77	281.00
IUUC-Pop-099871	Populus trichocarpa	32.79	1.00e-75	275.00
IUUC-Pca-100807	Procavia capensis	36.46	3.00e-27	114.00
IUUC-Ppe-101280	Prunus persica	32.91	1.00e-76	278.00
IUUC-Pva-102333	Pteropus vampyrus	33.51	4.00e-79	286.00
IUUC-Pgr-103401	Puccinia graminis	29.73	4.00e-66	244.00
IUUC-Ptt-103889	Puccinia triticina	29.69	5.00e-65	240.00
IUUC-Pte-104355	Pyrenophora teres	50.96	5.00e-159	552.00
IUUC-Pyt-104545	Pyrenophora triticirepentis	50.79	9.00e-158	548.00
IUUC-Rno-105810	Rattus norvegicus	34.17	2.00e-87	314.00
IUUC-Sce-106397	Saccharomyces cerevisiae	24.29	3.00e-29	120.00
IUUC-Sha-106770	Sarcophilus harrisii	39.66	1.00e-51	194.00
IUUC-Sja-107926	Schizosaccharomyces japonicus	31.38	6.00e-78	282.00
IUUC-Spo-108276	Schizosaccharomyces pombe	32.42	6.00e-79	286.00
IUUC-Ssl-108387	Sclerotinia sclerotiorum	47.54	1.00e-137	481.00
IUUC-Smo-109296	Selaginella moellendorffii	32.79	1.00e-74	271.00
IUUC-Sit-110157	Setaria italica	33.39	7.00e-78	282.00
IUUC-Sly-111105	Solanum lycopersicum	31.57	9.00e-75	272.00
IUUC-Stu-112469	Solanum tuberosum	32.04	1.00e-75	275.00
IUUC-Sar-113083	Sorex araneus	24.77	1.00e-44	172.00
IUUC-Sbi-113813	Sorghum bicolor	33.15	1.00e-75	275.00
IUUC-Sre-115058	Sporisorium reilianum	37.86	2.00e-68	251.00
IUUC-Tgu-116772	Taeniopygia guttata	33.63	3.00e-77	280.00
IUUC-Tru-118686	Takifugu rubripes	34.48	4.00e-90	323.00
IUUC-Tsy-119111	Tarsius syrichta	35.84	7.00e-42	163.00
IUUC-Tni-120231	Tetraodon nigroviridis	30.40	5.00e-72	263.00
IUUC-Tca-121491	Theobroma cacao	32.12	1.00e-70	259.00
IUUC-Tre-122103	Trichoderma reesei	46.50	8.00e-136	475.00
IUUC-Tvi-122672	Trichoderma virens	45.17	3.00e-134	470.00
IUUC-Tae-125684	Triticum aestivum	33.33	1.00e-76	278.00
IUUC-Tur-126487	Triticum urartu	32.55	6.00e-72	263.00
IUUC-Tme-127097	Tuber melanosporum	38.45	2.00e-96	344.00
IUUC-Ttr-128465	Tursiops truncatus	31.84	6.00e-73	266.00
IUUC-Uma-129645	Ustilago maydis	38.33	5.00e-71	260.00
IUUC-Vda-129989	Verticillium dahliae	39.86	4.00e-102	363.00
IUUC-Vpa-130529	Vicugna pacos	32.38	1.00e-75	275.00
IUUC-Vvi-131059	Vitis vinifera	31.51	3.00e-71	261.00
IUUC-Xtr-132002	Xenopus tropicalis	36.58	8.00e-94	335.00
IUUC-Xma-133930	Xiphophorus maculatus	35.78	4.00e-90	323.00
IUUC-Yli-134505	Yarrowia lipolytica	34.18	5.00e-83	299.00
IUUC-Zma-135619	Zea mays	32.97	1.00e-72	265.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence