iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020293

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03013008

Gene Name

UBE2D3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000024756.2	ENSCAFT00000038232.2	ENSCAFP00000033920.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.90e-50	170.0	2	128
UBD/UBC-like/UBD_UBC	7.00e-77	256.5	1	133

Active Site

Position(s)	Description	Evidence
76	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 7    kelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspa 95
           ++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+f +dYPfkPPkv ++t+i+hPn+++nG++Cl+il+  ++Wspa
   Q: 2    SDLARDPPAQCSAGPVWD-DMFHWQATIIGPNDSPYQGGVFFLTIHFLTDYPFKPPKVALTTRIYHPNINSNGSICLDILR--SQWSPA 87
           6899**************.9************************************************************9..****** PP
   S: 96   lsvesvllsiqsllaepnpesplneeaaellkknreeykkk 136
           l++++vllsi+sll++pnp++pl  e+a+++k++r +y+++
   Q: 88   LTISKVLLSICSLLCDPNPDDPLVPEIARIYKTERDKYNRI 128
           **************************************986 PP

UBD/UBC-like/UBD_UBC

   S: 6    lkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaalt 94
           l+dl+rd++aq+sa++v dd+f+++ati+gp+dspy+ggvfflti++ tdypfkppkva++t+iyhpninsngsicldilrsqws+alt
   Q: 1    LSDLARDPPAQCSAGPVWDDMFHWQATIIGPNDSPYQGGVFFLTIHFLTDYPFKPPKVALTTRIYHPNINSNGSICLDILRSQWSPALT 89
           68*************************************************************************************** PP
   S: 95   lskvllslcslladaepddplvaeiariyktdkekykriarewt 138
           +skvlls+csll+d++pddplv+eiariykt+++ky+ri++ewt
   Q: 90   ISKVLLSICSLLCDPNPDDPLVPEIARIYKTERDKYNRISQEWT 133
           *******************************************8 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

LSDLARDPPA QCSAGPVWDD MFHWQATIIG PNDSPYQGGV FFLTIHFLTD YPFKPPKVAL 60
TTRIYHPNIN SNGSICLDIL RSQWSPALTI SKVLLSICSL LCDPNPDDPL VPEIARIYKT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTAGTGATT TGGCCCGTGA CCCTCCAGCA CAATGTTCTG CAGGTCCTGT TTGGGATGAT 60
ATGTTTCATT GGCAAGCCAC AATTATAGGA CCTAATGACA GCCCATATCA AGGTGGTGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence