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Tag Content
iUUCD ID IUUC-Mpu-066024
Ensembl Protein ID ENSMPUP00000017158.1
UniProt Accession M3Z0P6; M3Z0P6_MUSPF
Genbank Protein ID ENSMPUP00000017158
Protein Name Uncharacterized protein
Genbank Nucleotide ID AEYP01046566
Gene Name PML
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMPUG00000017266.1 ENSMPUT00000017412.1 ENSMPUP00000017158.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 73.89 0.00e+00 1161.00 IUUC-Hsa-045861
E3 activity/RING/RING 62.53 0.00e+00 925.00 IUUC-Mmu-063118
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mustela putorius furo
Protein Sequence
(Fasta)
MQQEPAPARS PGPQQDPALL HTPTMPLPES VPEGHQPSPS PAEQALEEEF QFLRCQACQV 60
EAKRPKLLSC LHTLCSGCLE ASNLQCPICQ LPGPLGADSM VLDNVFFESL QRRLSVYRQI 120
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Protein Fasta Sequence



>IUUC-Mpu-066024|E3,RING|Mustela putorius furo
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Nucleotide Sequence
(Fasta)
CTCCTCACTG TCTTCATATC TGCTCACCAG TTCTCCCCCT TCCCTCCCTG CTCCTCTGCC 60
TCAGACTCAC CAACCTACCT CTCTAGCTAT CACCCAAGGC ACCGTCCTAT TCCCCTCAGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mpu-066024|E3,RING|Mustela putorius furo
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR021978--DUF3583
IPR012337--RNaseH-like_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12126--DUF3583
PF00643--zf-B_box

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0042406--C:extrinsic component of endoplasmic reticulum membrane
GO:0000784--C:nuclear chromosome, telomeric region
GO:0016363--C:nuclear matrix
GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0007050--P:cell cycle arrest
GO:0045165--P:cell fate commitment
GO:0071353--P:cellular response to interleukin-4
GO:0090398--P:cellular senescence
GO:0032922--P:circadian regulation of gene expression
GO:0007182--P:common-partner SMAD protein phosphorylation
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0032469--P:endoplasmic reticulum calcium ion homeostasis
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0097191--P:extrinsic apoptotic signaling pathway
GO:0010761--P:fibroblast migration
GO:0045087--P:innate immune response
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0051457--P:maintenance of protein location in nucleus
GO:0030099--P:myeloid cell differentiation
GO:0016525--P:negative regulation of angiogenesis
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0050713--P:negative regulation of interleukin-1 beta secretion
GO:2000059--P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1902187--P:negative regulation of viral release from host cell
GO:0030578--P:PML body organization
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0048146--P:positive regulation of fibroblast proliferation
GO:0045345--P:positive regulation of MHC class I biosynthetic process
GO:0032206--P:positive regulation of telomere maintenance
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006461--P:protein complex assembly
GO:0010522--P:regulation of calcium ion transport into cytosol
GO:0030155--P:regulation of cell adhesion
GO:2000779--P:regulation of double-strand break repair
GO:0001932--P:regulation of protein phosphorylation
GO:0010332--P:response to gamma radiation
GO:0001666--P:response to hypoxia
GO:0009411--P:response to UV
GO:0048384--P:retinoic acid receptor signaling pathway
GO:0007184--P:SMAD protein import into nucleus
GO:0007179--P:transforming growth factor beta receptor signaling pathway

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001901 Ailuropoda melanoleuca 80.93 0.00e+00 1224.00
IUUC-Bta-012427 Bos taurus 69.17 0.00e+00 1087.00
IUUC-Cja-019029 Callithrix jacchus 73.16 0.00e+00 1119.00
IUUC-Cfa-021127 Canis familiaris 74.85 0.00e+00 1136.00
IUUC-Cpo-022553 Cavia porcellus 64.70 0.00e+00 929.00
IUUC-Csa-023187 Chlorocebus sabaeus 70.91 0.00e+00 754.00
IUUC-Cho-024937 Choloepus hoffmanni 64.78 2.00e-90 327.00
IUUC-Dno-029326 Dasypus novemcinctus 70.24 0.00e+00 1030.00
IUUC-Dor-030808 Dipodomys ordii 58.17 0.00e+00 650.00
IUUC-Ete-032746 Echinops telfairi 53.53 7.00e-164 571.00
IUUC-Eca-033234 Equus caballus 73.92 0.00e+00 1086.00
IUUC-Fca-035648 Felis catus 79.20 0.00e+00 1231.00
IUUC-Ggo-044927 Gorilla gorilla 73.67 0.00e+00 1152.00
IUUC-Hsa-045861 Homo sapiens 73.89 0.00e+00 1157.00
IUUC-Itr-047861 Ictidomys tridecemlineatus 71.64 0.00e+00 1135.00
IUUC-Loc-052276 Lepisosteus oculatus 36.23 5.00e-52 199.00
IUUC-Laf-054059 Loxodonta africana 69.63 0.00e+00 1055.00
IUUC-Meu-056495 Macropus eugenii 52.87 2.00e-98 353.00
IUUC-Mga-059224 Meleagris gallopavo 44.49 9.00e-43 168.00
IUUC-Mmr-061507 Microcebus murinus 68.95 0.00e+00 1027.00
IUUC-Mdo-062196 Monodelphis domestica 45.21 4.00e-175 608.00
IUUC-Mmu-063118 Mus musculus 62.53 0.00e+00 962.00
IUUC-Mlu-066980 Myotis lucifugus 69.77 0.00e+00 1041.00
IUUC-Nle-069779 Nomascus leucogenys 72.99 0.00e+00 1103.00
IUUC-Ocu-074016 Oryctolagus cuniculus 60.93 0.00e+00 941.00
IUUC-Oga-089085 Otolemur garnettii 63.80 0.00e+00 967.00
IUUC-Oar-089980 Ovis aries 67.61 0.00e+00 1031.00
IUUC-Ptr-091681 Pan troglodytes 73.61 0.00e+00 1149.00
IUUC-Pan-091965 Papio anubis 71.28 0.00e+00 1073.00
IUUC-Psi-093577 Pelodiscus sinensis 35.98 6.00e-105 375.00
IUUC-Pab-098215 Pongo abelii 70.05 2.00e-159 556.00
IUUC-Pca-100883 Procavia capensis 66.67 0.00e+00 756.00
IUUC-Pva-102465 Pteropus vampyrus 70.87 0.00e+00 768.00
IUUC-Rno-105120 Rattus norvegicus 61.89 0.00e+00 996.00
IUUC-Sar-113320 Sorex araneus 58.28 4.00e-82 299.00
IUUC-Ssc-116042 Sus scrofa 71.88 0.00e+00 1128.00
IUUC-Tbe-127880 Tupaia belangeri 66.12 1.00e-131 463.00
Created Date 25-Jun-2017

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