iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088958

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03028575

Gene Name

RNF125

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000001232.2	ENSOGAT00000001234.2	ENSOGAP00000001104.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.30e-08	35.2	37	76
E3 activity/RING/U-box	1.10e-10	41.5	33	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C++Cle + + p+ ++CgHvf+++C+   +      ++++++CP+Cr
   Q: 37   CSVCLEVLHQ-PVRTRCGHVFCRSCIaTSL------KNNKWTCPYCR 76
           ********99.777***********95555......**********8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawc 69
             f C++ le+ ++Pv + +G+++ rs+I+  l++++ tcP +r+ l +e +    + +r+ +++ 
   Q: 33   TSFDCSVCLEVLHQPVRTRCGHVFCRSCIATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMKSEYQ 98
           579******************************99999*********9999999999999999885 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MGSVLSSDSG KSAPASATPR ALERRRDPEL PVTSFDCSVC LEVLHQPVRT RCGHVFCRSC 60
IATSLKNNKW TCPYCRAYLP SEGVPATDVA KRMKSEYQNC AECDTMVCLS DMRAHIRTCQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTCCG TGCTGAGCAG CGATAGTGGC AAATCGGCGC CCGCCTCTGC CACCCCGCGG 60
GCCCTGGAGC GCAGGAGGGA CCCAGAGCTG CCTGTCACGT CTTTCGACTG CTCAGTGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR008598--Di19_Zn_binding_dom
IPR034734--ZF_C2HC_RNF
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51803--ZF_C2HC_RNF
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF05605--zf-Di19

SMART

SM00184--RING

Gene Ontology

GO:0000139--C:Golgi membrane
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001992	Ailuropoda melanoleuca	92.67	3.00e-129	453.00
IUUC-Aca-004839	Anolis carolinensis	62.57	5.00e-67	246.00
IUUC-Bta-012827	Bos taurus	91.81	4.00e-127	446.00
IUUC-Bdi-014205	Brachypodium distachyon	43.08	1.00e-09	54.70
IUUC-Cja-018794	Callithrix jacchus	91.81	4.00e-127	446.00
IUUC-Cfa-021234	Canis familiaris	91.81	8.00e-119	419.00
IUUC-Cpo-022412	Cavia porcellus	80.17	8.00e-107	379.00
IUUC-Csa-023406	Chlorocebus sabaeus	93.53	8.00e-129	452.00
IUUC-Cho-024427	Choloepus hoffmanni	77.40	4.00e-76	276.00
IUUC-Dno-030085	Dasypus novemcinctus	94.40	8.00e-131	459.00
IUUC-Dor-030911	Dipodomys ordii	70.69	1.00e-77	282.00
IUUC-Ete-032469	Echinops telfairi	85.78	4.00e-119	420.00
IUUC-Eca-034352	Equus caballus	95.69	8.00e-132	462.00
IUUC-Eeu-034889	Erinaceus europaeus	79.31	1.00e-103	369.00
IUUC-Fca-036116	Felis catus	93.10	7.00e-122	429.00
IUUC-Hsa-046518	Homo sapiens	93.97	1.00e-129	454.00
IUUC-Itr-048344	Ictidomys tridecemlineatus	96.61	2.00e-101	360.00
IUUC-Laf-053363	Loxodonta africana	92.74	7.00e-128	449.00
IUUC-Meu-056101	Macropus eugenii	78.67	2.00e-96	345.00
IUUC-Mdo-062046	Monodelphis domestica	76.39	1.00e-100	358.00
IUUC-Mmu-063184	Mus musculus	86.43	3.00e-60	223.00
IUUC-Mpu-065708	Mustela putorius furo	91.81	2.00e-127	447.00
IUUC-Mlu-067561	Myotis lucifugus	89.27	2.00e-94	337.00
IUUC-Nle-069665	Nomascus leucogenys	91.59	3.00e-116	410.00
IUUC-Opr-070301	Ochotona princeps	80.17	1.00e-106	378.00
IUUC-Ocu-074562	Oryctolagus cuniculus	92.86	3.00e-67	246.00
IUUC-Oar-089541	Ovis aries	91.53	5.00e-97	345.00
IUUC-Ptr-090989	Pan troglodytes	94.40	1.00e-130	457.00
IUUC-Pan-092372	Papio anubis	92.67	4.00e-128	449.00
IUUC-Pab-098718	Pongo abelii	81.03	6.00e-105	372.00
IUUC-Pca-100453	Procavia capensis	90.95	6.00e-125	439.00
IUUC-Pva-102931	Pteropus vampyrus	94.40	3.00e-121	427.00
IUUC-Rno-105771	Rattus norvegicus	88.21	3.00e-101	360.00
IUUC-Sha-107557	Sarcophilus harrisii	76.39	7.00e-108	382.00
IUUC-Sar-113435	Sorex araneus	92.06	3.00e-67	246.00
IUUC-Ssc-116388	Sus scrofa	93.10	2.00e-129	454.00
IUUC-Tsy-119439	Tarsius syrichta	93.79	3.00e-99	353.00
IUUC-Tbe-127417	Tupaia belangeri	68.63	9.00e-72	262.00
IUUC-Ttr-129212	Tursiops truncatus	93.53	3.00e-130	457.00
IUUC-Vpa-130153	Vicugna pacos	92.67	1.00e-128	451.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence