iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037219

Ensembl Protein ID

ENSFALP00000012946.1

UniProt Accession

U3KD42; U3KD42_FICAL

Genbank Protein ID

ENSFALP00000012946

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01020832

Gene Name

EML5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000012371.1	ENSFALT00000012998.1	ENSFALP00000012946.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-59	195.3	770	808
UBD/Beta-Prp	1.60e-124	414.7	725	941

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgvll 36
           H+ +v++++f  d ++l+s +  d++ti +WD+++g +l
   Q: 770  HQYGVCAVDFsADgKRLASVGidDNHTIVLWDWKKGEKL 808
           8899*******666*******866699******999875 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           h++ i c++++p k+++atg  +rd++i +wd++t k l+ l   h+ +v av+fs dgk l++++ D  +ti +wd ++g+ +++++g
   Q: 725  HDDDILCLAIHPLKDYVATGqvGRDSSIHIWDTETIKPLSVLkGYHQYGVCAVDFSADGKRLASVGIDdnHTIVLWDWKKGEKLSAVRG 813
           4555566************96669******************5559******************9999999****************** PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqclee..........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
            +d++  ++++p+  dkl++ +  +  + w   +                   g++++ +c+v+  ++ + +sG+  + v +W  +  +
   Q: 814  SKDKIFVVKINPYMpDKLITVG-IKHMKFWRRAEP----GggligrkgciGALGRTDTMMCAVYGWTEEMAFSGTSTGDVCIW--RDVF 895
           ************9956666655.999999954332....123446788876789999**************************..889* PP
   S: 171  llrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
           l++t +  h+++v s+   +  k +v+g++dg v lwd   ++c++t+ 
   Q: 896  LIKTVKA-HDGPVFSMHALE--KGFVTGGKDGVVALWDDTFERCLKTYA 941
           *****98.********9888..67**********************996 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

GGGGGGGGHL RLEWVYGYRG HQCRNNLYYT AAKEIVYFVA GVGVVYSPRE HRQKFYLGHQ 60
DDIISLALHP ERVLVATGQV GKEPYICVWD SYTVQTVSVL KDVHTHGIAC LAFDLDGQRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG 60
GGGGGGGGGG GGGGGGGGGG GGGGGGGGGG GGCCACCTGC GGCTGGAGTG GGTCTACGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002225	Ailuropoda melanoleuca	91.22	0.00e+00	3669.00
IUUC-Apl-003360	Anas platyrhynchos	98.74	0.00e+00	3779.00
IUUC-Ame-011681	Astyanax mexicanus	87.69	0.00e+00	3587.00
IUUC-Bta-012838	Bos taurus	91.03	0.00e+00	3700.00
IUUC-Cja-019068	Callithrix jacchus	90.88	0.00e+00	3678.00
IUUC-Cfa-020531	Canis familiaris	91.76	0.00e+00	3740.00
IUUC-Cpo-022304	Cavia porcellus	88.83	0.00e+00	3497.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	33.97	1.00e-99	359.00
IUUC-Csa-023621	Chlorocebus sabaeus	90.78	0.00e+00	3383.00
IUUC-Cho-024944	Choloepus hoffmanni	72.23	0.00e+00	1424.00
IUUC-Dre-028772	Danio rerio	87.30	0.00e+00	3581.00
IUUC-Dno-030063	Dasypus novemcinctus	90.29	0.00e+00	3646.00
IUUC-Dor-030980	Dipodomys ordii	81.31	0.00e+00	1519.00
IUUC-Ete-032554	Echinops telfairi	90.20	0.00e+00	1024.00
IUUC-Eca-033909	Equus caballus	90.87	0.00e+00	3420.00
IUUC-Eeu-035180	Erinaceus europaeus	75.27	0.00e+00	1408.00
IUUC-Gmo-039146	Gadus morhua	83.17	0.00e+00	3384.00
IUUC-Gga-041095	Gallus gallus	98.53	0.00e+00	2800.00
IUUC-Gac-041341	Gasterosteus aculeatus	85.87	0.00e+00	3471.00
IUUC-Hsa-045997	Homo sapiens	91.18	0.00e+00	3687.00
IUUC-Lch-050306	Latimeria chalumnae	87.44	0.00e+00	3267.00
IUUC-Loc-052215	Lepisosteus oculatus	88.07	0.00e+00	3631.00
IUUC-Laf-054044	Loxodonta africana	89.92	0.00e+00	3655.00
IUUC-Mcc-054733	Macaca mulatta	91.13	0.00e+00	3681.00
IUUC-Meu-055977	Macropus eugenii	90.35	0.00e+00	1046.00
IUUC-Mga-059666	Meleagris gallopavo	96.61	0.00e+00	3702.00
IUUC-Mmr-060995	Microcebus murinus	91.27	0.00e+00	3682.00
IUUC-Mdo-062482	Monodelphis domestica	92.34	0.00e+00	3745.00
IUUC-Mmu-063533	Mus musculus	90.07	0.00e+00	3631.00
IUUC-Mpu-066704	Mustela putorius furo	91.08	0.00e+00	3695.00
IUUC-Mlu-067592	Myotis lucifugus	90.68	0.00e+00	3660.00
IUUC-Nle-069911	Nomascus leucogenys	91.22	0.00e+00	3689.00
IUUC-Ont-071966	Oreochromis niloticus	87.40	0.00e+00	3586.00
IUUC-Ola-086738	Oryzias latipes	86.56	0.00e+00	3524.00
IUUC-Oga-088436	Otolemur garnettii	89.90	0.00e+00	3627.00
IUUC-Oar-090153	Ovis aries	91.48	0.00e+00	3603.00
IUUC-Ptr-091008	Pan troglodytes	90.88	0.00e+00	3663.00
IUUC-Pan-092404	Papio anubis	91.50	0.00e+00	3690.00
IUUC-Psi-093417	Pelodiscus sinensis	95.10	0.00e+00	3675.00
IUUC-Pfo-096073	Poecilia formosa	87.53	0.00e+00	3590.00
IUUC-Pab-097900	Pongo abelii	90.62	0.00e+00	3665.00
IUUC-Pca-100107	Procavia capensis	76.16	0.00e+00	2413.00
IUUC-Pva-102880	Pteropus vampyrus	87.49	0.00e+00	3380.00
IUUC-Rno-106084	Rattus norvegicus	90.57	0.00e+00	3686.00
IUUC-Sha-106974	Sarcophilus harrisii	92.48	0.00e+00	3742.00
IUUC-Sar-113401	Sorex araneus	80.46	0.00e+00	1751.00
IUUC-Ssc-116057	Sus scrofa	90.75	0.00e+00	3622.00
IUUC-Tru-118444	Takifugu rubripes	86.51	0.00e+00	3503.00
IUUC-Tsy-118941	Tarsius syrichta	80.17	0.00e+00	2726.00
IUUC-Tni-120683	Tetraodon nigroviridis	85.86	0.00e+00	3365.00
IUUC-Tbe-127467	Tupaia belangeri	83.91	0.00e+00	1773.00
IUUC-Ttr-129138	Tursiops truncatus	87.48	0.00e+00	3394.00
IUUC-Vpa-130083	Vicugna pacos	86.01	0.00e+00	3307.00
IUUC-Xtr-131835	Xenopus tropicalis	90.54	0.00e+00	3699.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence