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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063757
UUCD1 version UUC-MuM-00933
Ensembl Protein ID ENSMUSP00000034529.7
UniProt Accession G3X914; G3X914_MOUSE
Genbank Protein ID EDL25800.1
Protein Name Cullin 5; Cullin-5
Genbank Nucleotide ID AC158384
Gene Name Cul5; mCG_5637
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000032030.16 ENSMUST00000034529.13 ENSMUSP00000034529.7
ENSMUSG00000032030.16 ENSMUST00000133872.1 ENSMUSP00000121734.1
ENSMUSG00000032030.16 ENSMUST00000166367.7 ENSMUSP00000133144.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarmiRNAMapRAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
CPLMPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/Cullin 6.00e-228 759.6 97 747
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/Cullin
   S: 2    lreavkkilrqesv.kkeyeelytavynlclsk..vgaklYkklkevleefikqvkkkveesedeq.lLktynreWekfreqlkvlrki 86
           ++ +v k+lrqesv k+++ +l+++v+++cl++  ++ k++++lke++ efikq++++v +++d++ lLk+y++eW+kf++q+++l+k+
   Q: 97   MHPIVLKLLRQESVtKQQWFDLFSDVHAVCLWDdkGSSKIHQALKEDILEFIKQAQARVLSHQDDTaLLKAYIVEWRKFFTQCDILPKP 185
           6789****************************9999***************************************************** PP
   S: 87   fayldrtyvkk...skkv......sevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveLslnk...lai 163
           f++l+ t  +k   +  +      s vrkL+ld+w+++i+++ik+rl+++++kl++aeR gea+d++l+ gv+es+v+L++n    l+i
   Q: 186  FCQLEVTLLGKqssN--KksnmedSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPedkLQI 272
           **********96541..246667899*******************************************************99999*** PP
   S: 164  ykesFEakfleatqefykaesaeflqenevdeYlkkvearlneeeeraaryleestetk....Llevvekeliakhlesllaelvallr 248
           y+++FE+++l++t++fy++++ ++lq+n+v++Y+k+++a+l+eee+ra ryle+++e++    L+e+++++l++++ e++lae++ +++
   Q: 273  YRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNsveaLMECCVNALVTSFKETILAECQGMIK 361
           *********************************************************999999************************** PP
   S: 249  dkktedlsrmykLlsrvlngleellkeleshikeqgkaalt..aeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafet 335
           +++te+l++m++L+++v+ng+e++lk+le+hi ++g+a+++  ae++++d++kyVe+ll+l+n+++klv+eaF++d++Fl+a+dka+++
   Q: 362  RNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVaaAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKA 450
           ****************************************99999******************************************** PP
   S: 336  fvnknsvlka................akspEllAryiDqlLrks..skglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLls 406
           +vn+++++k+                +k+pEllA+y+D+lLrk+  sk+lt+ee+ea+l++vllv+ky+++kdvF++y+k hL++RL++
   Q: 451  VVNDATIFKLelplkqkgvglktqpeSKCPELLANYCDMLLRKTplSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLIL 539
           ***************************************************************************************** PP
   S: 407  gksasseaEesviekLkeec.gaeftskLerMfqdlkvSedlnrqFk.eekenteesesvelsvlvLsagaWptasetekvsLPaelek 493
           ++sa+se+Ee+++e+L+e++ +a++++kL+rMfqd+kvSedln++Fk ++k+n+ + +++++++++L+agaW+++se++ vsLP+ele+
   Q: 540  DISADSEIEENMVEWLREVGmPADYVNKLARMFQDIKVSEDLNQAFKeMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELED 628
           ***********************************************5688888899******************************** PP
   S: 494  tiekfeefYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnns..ekvsveelkkatelpeeeLrrtlqsLvs.sk 579
           +i+++eefY+++hsgRkL+W+h ++++ +++++++g+y+l+V+tfQ+avL+a+n++  ek+s+e+lk atelp++eLrrtl+sLv+ +k
   Q: 629  LIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRprEKISFENLKLATELPDAELRRTLWSLVAfPK 717
           *******************************************************999****************************999 PP
   S: 580  ..kqvlkkepeske...ieeedlfsvNqef 604
             +qvl ++p+ ++   ++e++lfsvNq+f
   Q: 718  lkRQVLLYDPQVNSpkdFTEGTLFSVNQDF 747
           999********977778***********99 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MRSLAWAGRG DHVAGKPEEA RLPGTSSALT ARRSGVPRIP RRGLRGPAGN PGLSRRPGPE 60
RRQVSPRLAR VQVENMATSN LLKNKGSLQF EDKWDFMHPI VLKLLRQESV TKQQWFDLFS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063757|E3,Cullin|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TAATAAAGAC TTGCCTTACA ATGGCTGGGC CAATGGAGAG AGGGCAGGAC CTGGAGAATT 60
GCAAGGGCTA GATAACCAGA CTAGAGGAAG AGAGGAAGGA CTGGATATAA GAACAGCAAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063757|E3,Cullin|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8
SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8
Gene Ontology

GO:0031466--C:Cul5-RING ubiquitin ligase complex
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002082 Ailuropoda melanoleuca 97.31 0.00e+00 1532.00
IUUC-Apl-003564 Anas platyrhynchos 98.06 0.00e+00 1533.00
IUUC-Aca-004319 Anolis carolinensis 97.82 0.00e+00 1546.00
IUUC-Ame-011742 Astyanax mexicanus 95.39 0.00e+00 1509.00
IUUC-Bta-012515 Bos taurus 98.42 0.00e+00 1507.00
IUUC-Cel-018522 Caenorhabditis elegans 51.35 0.00e+00 754.00
IUUC-Cja-018785 Callithrix jacchus 98.33 0.00e+00 1550.00
IUUC-Cfa-020932 Canis familiaris 98.29 0.00e+00 1505.00
IUUC-Cpo-022317 Cavia porcellus 98.21 0.00e+00 1549.00
IUUC-Csa-023949 Chlorocebus sabaeus 98.46 0.00e+00 1552.00
IUUC-Cho-024570 Choloepus hoffmanni 96.74 2.00e-124 439.00
IUUC-Cin-025540 Ciona intestinalis 72.21 1.00e-149 522.00
IUUC-Csv-025978 Ciona savignyi 64.54 0.00e+00 996.00
IUUC-Dre-027958 Danio rerio 95.51 0.00e+00 1526.00
IUUC-Dno-029195 Dasypus novemcinctus 98.20 0.00e+00 1541.00
IUUC-Dor-030573 Dipodomys ordii 86.67 2.00e-172 598.00
IUUC-Dme-032083 Drosophila melanogaster 67.68 0.00e+00 915.00
IUUC-Ete-032428 Echinops telfairi 81.67 0.00e+00 1222.00
IUUC-Eca-033232 Equus caballus 98.33 0.00e+00 1550.00
IUUC-Eeu-035348 Erinaceus europaeus 98.71 0.00e+00 749.00
IUUC-Fca-035401 Felis catus 97.81 0.00e+00 1513.00
IUUC-Fal-037514 Ficedula albicollis 94.11 0.00e+00 1532.00
IUUC-Gmo-038577 Gadus morhua 92.98 0.00e+00 1477.00
IUUC-Gga-041096 Gallus gallus 97.81 0.00e+00 1533.00
IUUC-Gac-042108 Gasterosteus aculeatus 93.87 0.00e+00 1490.00
IUUC-Ggo-045313 Gorilla gorilla 97.95 0.00e+00 1544.00
IUUC-Hsa-045974 Homo sapiens 98.46 0.00e+00 1552.00
IUUC-Itr-049009 Ictidomys tridecemlineatus 94.28 0.00e+00 1618.00
IUUC-Lch-050615 Latimeria chalumnae 97.50 0.00e+00 1495.00
IUUC-Loc-051807 Lepisosteus oculatus 96.79 0.00e+00 1528.00
IUUC-Laf-053601 Loxodonta africana 98.32 0.00e+00 1539.00
IUUC-Mcc-055260 Macaca mulatta 93.02 0.00e+00 1582.00
IUUC-Meu-056632 Macropus eugenii 98.13 0.00e+00 944.00
IUUC-Mga-059658 Meleagris gallopavo 97.81 0.00e+00 1532.00
IUUC-Mmr-061424 Microcebus murinus 88.19 0.00e+00 1337.00
IUUC-Mdo-061836 Monodelphis domestica 98.08 0.00e+00 1547.00
IUUC-Mpu-065823 Mustela putorius furo 98.21 0.00e+00 1550.00
IUUC-Mlu-066969 Myotis lucifugus 98.19 0.00e+00 1534.00
IUUC-Nle-069943 Nomascus leucogenys 98.46 0.00e+00 1552.00
IUUC-Opr-070820 Ochotona princeps 98.62 0.00e+00 856.00
IUUC-Ont-071599 Oreochromis niloticus 95.51 0.00e+00 1515.00
IUUC-Oan-072743 Ornithorhynchus anatinus 98.02 0.00e+00 1504.00
IUUC-Ocu-074586 Oryctolagus cuniculus 98.46 0.00e+00 1552.00
IUUC-Ola-087526 Oryzias latipes 95.26 0.00e+00 1514.00
IUUC-Oga-088425 Otolemur garnettii 93.81 0.00e+00 1499.00
IUUC-Oar-089785 Ovis aries 98.46 0.00e+00 1552.00
IUUC-Ptr-091242 Pan troglodytes 98.46 0.00e+00 1552.00
IUUC-Pan-092246 Papio anubis 98.46 0.00e+00 1552.00
IUUC-Psi-094081 Pelodiscus sinensis 98.06 0.00e+00 1538.00
IUUC-Pma-094735 Petromyzon marinus 81.57 0.00e+00 741.00
IUUC-Pfo-097305 Poecilia formosa 94.88 0.00e+00 1504.00
IUUC-Pab-098248 Pongo abelii 92.31 0.00e+00 1430.00
IUUC-Pca-100756 Procavia capensis 87.31 0.00e+00 868.00
IUUC-Pva-102990 Pteropus vampyrus 84.59 0.00e+00 903.00
IUUC-Rno-105887 Rattus norvegicus 99.06 0.00e+00 1714.00
IUUC-Sha-107016 Sarcophilus harrisii 98.08 0.00e+00 1547.00
IUUC-Sar-113558 Sorex araneus 92.62 0.00e+00 1466.00
IUUC-Ssc-115414 Sus scrofa 98.46 0.00e+00 1552.00
IUUC-Tgu-116801 Taeniopygia guttata 97.05 0.00e+00 1524.00
IUUC-Tru-117565 Takifugu rubripes 94.74 0.00e+00 1508.00
IUUC-Tsy-119292 Tarsius syrichta 93.20 0.00e+00 1364.00
IUUC-Tni-120471 Tetraodon nigroviridis 94.88 0.00e+00 1505.00
IUUC-Tbe-127838 Tupaia belangeri 92.95 0.00e+00 1485.00
IUUC-Ttr-128345 Tursiops truncatus 98.08 0.00e+00 1546.00
IUUC-Vpa-130191 Vicugna pacos 89.40 0.00e+00 841.00
IUUC-Xtr-132810 Xenopus tropicalis 97.31 0.00e+00 1537.00
Created Date 25-Jun-2017

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