iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073152

UUCD1 version

UUC-OrA-00765

Ensembl Protein ID

ENSOANP00000002869.2

UniProt Accession

F7CYB0; F7CYB0_ORNAN

Protein Name

Uncharacterized protein

Gene Name

UBE2A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000001807.2	ENSOANT00000002870.2	ENSOANP00000002869.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.30e-40	136.4	17	109

Active Site

Position(s)	Description	Evidence
55	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 44   ggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesvllsiqsllaepnpesplneeaaellkknree 132
            g+Fkl+ief+e+YP kPP+v+f++k+fhPnvy++G++Cl+il+  ++Wsp+++v+s+l+siqsll+epnp+sp+n++aa+l+++n++e
   Q: 17   SGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQ--NRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKRE 103
           689****************************************9..******************************************* PP
   S: 133  ykkkvr 138
           y+k+v+
   Q: 104  YEKRVS 109
           ***996 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

PEGTPFEDGK LAGKGASGTF KLTIEFTEEY PNKPPTVRFV SKMFHPNVYA DGSICLDILQ 60
NRWSPTYDVS SILTSIQSLL DEPNPNSPAN SQAAQLYQEN KREYEKRVSA IVEQSWRDC 119

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGAGGGGA CCCCATTTGA AGACGGTAAG TTGGCCGGGA AGGGGGCGTG TATGTGTGTG 60
TGTTGGCGGG AGGAGGGGGG GGGGGGCTTT CTCCATGTCC TCGGGTTGTT GATGATGATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0001741--C:XY body
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006281--P:DNA repair
GO:0033522--P:histone H2A ubiquitination
GO:0016574--P:histone ubiquitination
GO:0060135--P:maternal process involved in female pregnancy
GO:0008284--P:positive regulation of cell proliferation
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000296	Aegilops tauschii	78.79	3.00e-46	176.00
IUUC-Cho-025061	Choloepus hoffmanni	89.92	1.00e-58	216.00
IUUC-Mga-059738	Meleagris gallopavo	100.00	4.00e-58	214.00
IUUC-Olo-080729	Oryza longistaminata	78.79	4.00e-46	176.00
IUUC-Ome-081958	Oryza meridionalis	75.47	2.00e-46	178.00
IUUC-Sar-113410	Sorex araneus	90.91	3.00e-59	219.00
IUUC-Tsy-119605	Tarsius syrichta	92.44	9.00e-61	224.00
IUUC-Tae-124497	Triticum aestivum	79.00	2.00e-46	177.00
IUUC-Tbe-128142	Tupaia belangeri	90.08	4.00e-59	218.00
IUUC-Vpa-130366	Vicugna pacos	100.00	2.00e-57	213.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence