iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026090

UUCD1 version

UUC-CiS-00381

Ensembl Protein ID

ENSCSAVP00000017634.1

UniProt Accession

H2ZJ68; H2ZJ68_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000010382.1	ENSCSAVT00000017826.1	ENSCSAVP00000017634.1
ENSCSAVG00000010382.1	ENSCSAVT00000017827.1	ENSCSAVP00000017635.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.10e-87	293.1	452	792

Active Site

Position(s)	Description	Evidence
760	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpd....lglflysen.dketlqpnpdsglknpehlklFeflGrllgkalqdg 85
           s++ +++ v+f+gE gld+gG++re+++ll+k +++++     g+f+  ++  ++ + pnp+s l    + k+Fef+G+++gk+l ++
   Q: 452  SEWCRQFVVKFKGETGLDWGGLNREWIHLLCKIFFQSKevggCGIFRSMNDdPQSLVLPNPSSTL----KPKYFEFAGKIVGKCLLES 535
           67888999******************************99999***8888835666678888875....68****************9 PP
   S: 86   .......rlldlplsksfyklllgkklsledleevdpelyks.lkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
                  r + +++++sf+ +l+g + ++ ++e+ dp+ly s +k+i+en   d+++++l+++ ++ +++    k++eL+p+G+n+ V
   Q: 536  aiggeysRQVTARFARSFLAQLIGLPATFAHFESDDPDLYMSkVKYILEN---DVTDAELTFSEEQFTSHGALKKVVELVPNGANVAV 620
           9999999***********************************9*****99...9***9999988888888999999************ PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspai.qwFwev 252
           tneNk +Y ++v++yrl e+ik ++e f +G+ +++p +lls+F+e+elel++cG+++i+ ed+k ++  +gg++ + +++  wFw++
   Q: 621  TNENKIKYLNRVAQYRLSESIKAELEMFIKGLASLVPDQLLSVFDENELELVLCGSSHISPEDFKLHCVINGGTNGSFQKVlSWFWSI 708
           ***************************************************************************99665449***** PP
   S: 253  leefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           +++f+++e +++LqF+Tg+s+lP  Gf++l+pr f i++ + ++  lP ++TCfn L+LP+Y+s+++l+++L + i+e+ +gF+l
   Q: 709  ISSFTQDELARLLQFTTGCSQLPSDGFKALEPR-FRISNiEYKTGGLPMAHTCFNELCLPNYDSYDELHKMLKISITEGiTGFGL 792
           *******************************99.6666669999***************************************97 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

MVLFVVIAIV SGICILNWFR KVVYRVEQTA EGNLFKYIRG NYLDLSKCVV CWGWNEPIDV 60
GETLSFHIEF FYSNGSHYPV CESDDIKVLI STHQRDDIPH VKEYSGRKYC KENVVSVSFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGTTGTAGC ATTTGCAAGC GTTACAGCCA TGTTAGCATT AGCTATGTAG TTCGCACGAG 60
TTTCATTTCC GCCTTTTTAT AACTTCCAAC GATTTATCCG GTTTCTAGTG GTGACAAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR017868--Filamin/ABP280_repeat-like
IPR001298--Filamin/ABP280_rpt
IPR000569--HECT_dom
IPR013783--Ig-like_fold
IPR014756--Ig_E-set

PROSITE

PS50194--FILAMIN_REPEAT
PS50237--HECT

Pfam

PF00630--Filamin
PF00632--HECT

SMART

SM00119--HECTc
SM00557--IG_FLMN

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001308	Ailuropoda melanoleuca	40.00	2.00e-170	591.00
IUUC-Apl-004071	Anas platyrhynchos	40.12	3.00e-168	583.00
IUUC-Aca-005218	Anolis carolinensis	40.91	2.00e-172	597.00
IUUC-Ame-011871	Astyanax mexicanus	41.78	0.00e+00	625.00
IUUC-Bta-012978	Bos taurus	40.55	2.00e-171	594.00
IUUC-Cja-019081	Callithrix jacchus	40.25	6.00e-171	592.00
IUUC-Cfa-020736	Canis familiaris	39.43	5.00e-163	566.00
IUUC-Cpo-021581	Cavia porcellus	40.12	4.00e-170	590.00
IUUC-Cho-024751	Choloepus hoffmanni	40.22	7.00e-168	582.00
IUUC-Cin-025773	Ciona intestinalis	73.48	0.00e+00	973.00
IUUC-Dre-027788	Danio rerio	41.51	3.00e-179	620.00
IUUC-Dno-030022	Dasypus novemcinctus	40.37	9.00e-172	595.00
IUUC-Dme-031577	Drosophila melanogaster	41.40	3.00e-175	607.00
IUUC-Ete-032402	Echinops telfairi	37.87	1.00e-161	562.00
IUUC-Eca-033908	Equus caballus	40.25	6.00e-171	592.00
IUUC-Eeu-034869	Erinaceus europaeus	50.21	2.00e-132	464.00
IUUC-Fca-036023	Felis catus	40.12	6.00e-171	592.00
IUUC-Fal-037477	Ficedula albicollis	40.12	7.00e-171	592.00
IUUC-Gmo-039197	Gadus morhua	41.29	6.00e-176	609.00
IUUC-Gga-040704	Gallus gallus	40.37	1.00e-169	588.00
IUUC-Gac-041511	Gasterosteus aculeatus	41.04	2.00e-178	617.00
IUUC-Ggo-044527	Gorilla gorilla	39.21	8.00e-161	559.00
IUUC-Hsa-046082	Homo sapiens	40.25	3.00e-171	593.00
IUUC-Itr-048168	Ictidomys tridecemlineatus	40.00	4.00e-170	590.00
IUUC-Lch-049772	Latimeria chalumnae	40.25	9.00e-162	562.00
IUUC-Loc-052541	Lepisosteus oculatus	41.58	2.00e-177	614.00
IUUC-Laf-053852	Loxodonta africana	40.00	3.00e-170	590.00
IUUC-Meu-056247	Macropus eugenii	27.62	2.00e-53	202.00
IUUC-Mga-060161	Meleagris gallopavo	40.64	4.00e-168	583.00
IUUC-Mmr-061447	Microcebus murinus	40.00	2.00e-169	587.00
IUUC-Mdo-062110	Monodelphis domestica	39.88	1.00e-166	578.00
IUUC-Mmu-064349	Mus musculus	38.88	5.00e-171	593.00
IUUC-Mpu-065824	Mustela putorius furo	40.00	1.00e-170	591.00
IUUC-Mlu-067729	Myotis lucifugus	40.12	2.00e-170	591.00
IUUC-Nle-069721	Nomascus leucogenys	40.25	3.00e-171	593.00
IUUC-Opr-070189	Ochotona princeps	40.32	2.00e-169	587.00
IUUC-Ont-072122	Oreochromis niloticus	41.08	2.00e-178	617.00
IUUC-Oan-072700	Ornithorhynchus anatinus	49.04	4.00e-132	463.00
IUUC-Ocu-074057	Oryctolagus cuniculus	40.25	2.00e-170	590.00
IUUC-Ola-087492	Oryzias latipes	41.81	4.00e-180	623.00
IUUC-Oga-088084	Otolemur garnettii	40.17	3.00e-170	590.00
IUUC-Oar-090354	Ovis aries	40.00	3.00e-167	580.00
IUUC-Ptr-091456	Pan troglodytes	40.25	6.00e-171	592.00
IUUC-Pan-092596	Papio anubis	39.83	1.00e-168	585.00
IUUC-Psi-092942	Pelodiscus sinensis	40.87	5.00e-171	593.00
IUUC-Pma-094662	Petromyzon marinus	42.60	5.00e-136	476.00
IUUC-Pfo-096838	Poecilia formosa	41.16	3.00e-175	607.00
IUUC-Pab-097849	Pongo abelii	40.12	1.00e-170	592.00
IUUC-Pca-100498	Procavia capensis	30.04	3.00e-56	211.00
IUUC-Pva-102599	Pteropus vampyrus	40.25	3.00e-170	590.00
IUUC-Rno-105776	Rattus norvegicus	38.76	1.00e-170	591.00
IUUC-Sha-106699	Sarcophilus harrisii	39.50	3.00e-167	580.00
IUUC-Sar-113621	Sorex araneus	39.88	4.00e-168	583.00
IUUC-Ssc-115742	Sus scrofa	40.32	2.00e-171	594.00
IUUC-Tgu-116490	Taeniopygia guttata	39.88	3.00e-170	590.00
IUUC-Tru-117679	Takifugu rubripes	41.41	1.00e-176	611.00
IUUC-Tsy-119607	Tarsius syrichta	42.19	5.00e-134	469.00
IUUC-Tni-120376	Tetraodon nigroviridis	41.31	6.00e-174	602.00
IUUC-Tbe-127348	Tupaia belangeri	44.21	3.00e-73	267.00
IUUC-Ttr-128786	Tursiops truncatus	51.16	2.00e-128	451.00
IUUC-Vpa-130180	Vicugna pacos	36.31	1.00e-114	405.00
IUUC-Xtr-132631	Xenopus tropicalis	40.41	1.00e-170	592.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence