iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115280

Ensembl Protein ID

ENSSSCP00000009065.2

UniProt Accession

F1S4P0; F1S4P0_PIG

Genbank Protein ID

ENSSSCP00000009065

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

CU570644

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000008499.2	ENSSSCT00000009301.2	ENSSSCP00000009065.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-29	100.5	567	599
UBD/Beta-Prp	2.20e-45	155.4	563	777

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           gHtd v++la+   +  +l+s+s Dgt+++W+++
   Q: 567  GHTDAVWGLAYsaaH-QRLLSCSADGTLRLWNTT 599
           8**********9853.89**************76 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk......ghedsvlslsfspsgdklvsGshdrtirvwdletgqc 128
             l gh+++v+ + +s   + l+++s D+t+++w+     +  ++       g  +sv ++s++p  +++v+  +  +  ++++et+q 
   Q: 563  GPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFndnqelGIPASVDLVSSDP--SHMVASFSKGYTSIFNMETQQR 649
           5689******************************8887766666661444444444555566666..8888888899************ PP
   S: 129  lee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqt 211
           + +        ++ +  +n v +hp+  + ++++ Dr ++++d +tgkl++ +   h ++v+sl++d+ng +l+sgs+d +++lw+l++
   Q: 650  ILTlesnldSTTNSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVA-HLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLES 737
           **9999977555555667888899*99**************************98.********************************* PP
   S: 212  gecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           ++c++++++h+    + + +v+f+p + +++s+++D   +
   Q: 738  KTCIQEFTAHRkkfeESIHDVAFHPSKCYIASAGADALAK 777
           ***********999999******************97655 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MDEQAGPGVF FSNNHPGASG AKGLGPLAEA AAAGDGAAAA GAARAQYSLP GILHFLQHEW 60
ARFEVERAQW EVERAELQAQ IAFLQGERKG QENLKKDLVR RIKMLEYALK QERAKYHKLK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCCCGCGA CTACATTTCC CAGCAAGCCC CGCGCCGCCC GCGCACCGCA GTTGACCCAT 60
TTCCCGGCCC GTCCCGAGCT CGGCCGGCCC CCGCGCCCAG GCGGCTGCTC CCTGCTGACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

KEGG

ssc:100524371

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	98.10	0.00e+00	1364.00
IUUC-Apl-003927	Anas platyrhynchos	88.09	0.00e+00	1130.00
IUUC-Aca-004933	Anolis carolinensis	81.15	0.00e+00	1158.00
IUUC-Ani-009405	Aspergillus nidulans	27.20	5.00e-32	132.00
IUUC-Ame-010997	Astyanax mexicanus	73.90	0.00e+00	1078.00
IUUC-Bta-013077	Bos taurus	97.95	0.00e+00	1387.00
IUUC-Cel-018443	Caenorhabditis elegans	48.36	4.00e-101	362.00
IUUC-Cja-018973	Callithrix jacchus	98.59	0.00e+00	1394.00
IUUC-Cfa-020988	Canis familiaris	94.74	0.00e+00	1237.00
IUUC-Cpo-022496	Cavia porcellus	97.56	0.00e+00	1392.00
IUUC-Csa-023829	Chlorocebus sabaeus	97.57	0.00e+00	1383.00
IUUC-Cho-024338	Choloepus hoffmanni	61.07	0.00e+00	772.00
IUUC-Cin-025167	Ciona intestinalis	47.68	1.00e-177	616.00
IUUC-Csv-026143	Ciona savignyi	49.93	0.00e+00	655.00
IUUC-Cgl-026487	Colletotrichum gloeosporioides	39.76	4.00e-18	86.30
IUUC-Dre-028560	Danio rerio	69.25	0.00e+00	976.00
IUUC-Dno-029742	Dasypus novemcinctus	92.18	0.00e+00	1320.00
IUUC-Dor-030721	Dipodomys ordii	89.36	0.00e+00	1261.00
IUUC-Dse-031486	Dothistroma septosporum	26.67	5.00e-35	142.00
IUUC-Dme-032158	Drosophila melanogaster	61.60	5.00e-138	484.00
IUUC-Ete-032770	Echinops telfairi	56.20	0.00e+00	764.00
IUUC-Eca-033760	Equus caballus	97.72	0.00e+00	1287.00
IUUC-Eeu-034953	Erinaceus europaeus	97.14	0.00e+00	754.00
IUUC-Fca-036530	Felis catus	97.58	0.00e+00	1292.00
IUUC-Fal-037353	Ficedula albicollis	81.65	0.00e+00	899.00
IUUC-Fso-038364	Fusarium solani	42.57	5.00e-23	102.00
IUUC-Gmo-039653	Gadus morhua	51.67	0.00e+00	708.00
IUUC-Ggr-039846	Gaeumannomyces graminis	38.83	2.00e-22	100.00
IUUC-Gga-040132	Gallus gallus	88.16	0.00e+00	1146.00
IUUC-Gac-041713	Gasterosteus aculeatus	73.58	0.00e+00	1062.00
IUUC-Ggo-045455	Gorilla gorilla	85.97	0.00e+00	1185.00
IUUC-Hsa-046415	Homo sapiens	98.21	0.00e+00	1389.00
IUUC-Itr-048177	Ictidomys tridecemlineatus	67.39	0.00e+00	644.00
IUUC-Lch-050475	Latimeria chalumnae	81.65	0.00e+00	1187.00
IUUC-Loc-051859	Lepisosteus oculatus	77.85	0.00e+00	1135.00
IUUC-Laf-053537	Loxodonta africana	97.18	0.00e+00	1398.00
IUUC-Mcc-055817	Macaca mulatta	97.32	0.00e+00	1382.00
IUUC-Meu-055946	Macropus eugenii	70.55	0.00e+00	916.00
IUUC-Mor-057148	Magnaporthe oryzae	43.66	2.00e-17	84.70
IUUC-Mpo-057337	Magnaporthe poae	24.80	9.00e-29	122.00
IUUC-Mla-058988	Melampsora laricipopulina	34.86	9.00e-63	235.00
IUUC-Mga-059694	Meleagris gallopavo	88.21	0.00e+00	1123.00
IUUC-Mmr-060768	Microcebus murinus	98.85	0.00e+00	1417.00
IUUC-Mdo-061901	Monodelphis domestica	87.41	0.00e+00	1321.00
IUUC-Mmu-064154	Mus musculus	96.92	0.00e+00	1377.00
IUUC-Mpu-065827	Mustela putorius furo	93.33	0.00e+00	1379.00
IUUC-Mlu-067102	Myotis lucifugus	97.55	0.00e+00	1356.00
IUUC-Ncr-068831	Neurospora crassa	39.60	5.00e-22	99.80
IUUC-Nle-070008	Nomascus leucogenys	98.15	0.00e+00	1295.00
IUUC-Opr-071067	Ochotona princeps	61.47	5.00e-179	620.00
IUUC-Ont-072025	Oreochromis niloticus	73.54	0.00e+00	1054.00
IUUC-Oan-072950	Ornithorhynchus anatinus	92.37	0.00e+00	1175.00
IUUC-Ocu-074316	Oryctolagus cuniculus	97.30	0.00e+00	1278.00
IUUC-Ola-087279	Oryzias latipes	71.57	0.00e+00	1032.00
IUUC-Oga-088284	Otolemur garnettii	98.33	0.00e+00	1394.00
IUUC-Oar-090304	Ovis aries	98.46	0.00e+00	1394.00
IUUC-Ptr-091052	Pan troglodytes	98.33	0.00e+00	1390.00
IUUC-Pan-092270	Papio anubis	91.94	0.00e+00	1342.00
IUUC-Psi-093907	Pelodiscus sinensis	88.48	0.00e+00	1051.00
IUUC-Pma-094286	Petromyzon marinus	66.07	0.00e+00	633.00
IUUC-Pno-094905	Phaeosphaeria nodorum	26.58	3.00e-31	130.00
IUUC-Pfo-097042	Poecilia formosa	72.82	0.00e+00	1137.00
IUUC-Pab-098110	Pongo abelii	98.33	0.00e+00	1390.00
IUUC-Pca-100266	Procavia capensis	85.97	0.00e+00	999.00
IUUC-Pva-102824	Pteropus vampyrus	95.64	0.00e+00	1359.00
IUUC-Pgr-103483	Puccinia graminis	36.99	3.00e-56	213.00
IUUC-Ptt-103828	Puccinia triticina	36.75	3.00e-46	180.00
IUUC-Rno-105638	Rattus norvegicus	97.18	0.00e+00	1385.00
IUUC-Sha-107004	Sarcophilus harrisii	88.97	0.00e+00	1133.00
IUUC-Sre-115115	Sporisorium reilianum	33.85	2.00e-63	237.00
IUUC-Tgu-116759	Taeniopygia guttata	88.64	0.00e+00	1147.00
IUUC-Tru-117944	Takifugu rubripes	73.42	0.00e+00	1059.00
IUUC-Tsy-119405	Tarsius syrichta	86.47	0.00e+00	1082.00
IUUC-Tni-120571	Tetraodon nigroviridis	72.98	0.00e+00	1066.00
IUUC-Tme-126990	Tuber melanosporum	25.91	8.00e-35	142.00
IUUC-Tbe-127691	Tupaia belangeri	56.84	3.00e-150	525.00
IUUC-Ttr-128600	Tursiops truncatus	61.84	0.00e+00	844.00
IUUC-Uma-129659	Ustilago maydis	34.70	8.00e-64	238.00
IUUC-Vpa-130294	Vicugna pacos	97.72	0.00e+00	1279.00
IUUC-Xtr-132330	Xenopus tropicalis	63.12	0.00e+00	914.00
IUUC-Xma-134233	Xiphophorus maculatus	67.96	0.00e+00	908.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence